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Volumn 165, Issue 5, 2014, Pages 585-599

Antithrombotic treatment for pregnancy complications: Which path for the journey to precision medicine?

Author keywords

Antithrombotic treatment; Pregnancy

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; COMPLEMENT COMPONENT C5A; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; THROMBOMODULIN; FIBRINOLYTIC AGENT;

EID: 84900518217     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12813     Document Type: Review
Times cited : (41)

References (117)
  • 1
    • 79958045457 scopus 로고    scopus 로고
    • The association between antiphospholipid antibodies and placenta mediated complications: a systematic review and meta-analysis
    • Abou-Nassar, K., Carrier, M., Ramsay, T. & Rodger, M.A. (2011) The association between antiphospholipid antibodies and placenta mediated complications: a systematic review and meta-analysis. Thrombosis Research, 128, 77-85.
    • (2011) Thrombosis Research , vol.128 , pp. 77-85
    • Abou-Nassar, K.1    Carrier, M.2    Ramsay, T.3    Rodger, M.A.4
  • 2
    • 6344244577 scopus 로고    scopus 로고
    • Tissue factor and tissue factor pathway inhibitor levels in trophoblast cells: implications for placental hemostasis
    • Aharon, A., Brenner, B., Katz, T., Miyagi, Y. & Lanir, N. (2004) Tissue factor and tissue factor pathway inhibitor levels in trophoblast cells: implications for placental hemostasis. Thrombosis and Haemostasis, 92, 776-786.
    • (2004) Thrombosis and Haemostasis , vol.92 , pp. 776-786
    • Aharon, A.1    Brenner, B.2    Katz, T.3    Miyagi, Y.4    Lanir, N.5
  • 3
    • 28444450102 scopus 로고    scopus 로고
    • Placental TFPI is decreased in gestational vascular complications and can be restored by maternal enoxaparin treatment
    • Aharon, A., Lanir, N., Drugan, A. & Brenner, B. (2005) Placental TFPI is decreased in gestational vascular complications and can be restored by maternal enoxaparin treatment. Journal of Thrombosis and Haemostasis, 3, 2355-2357.
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , pp. 2355-2357
    • Aharon, A.1    Lanir, N.2    Drugan, A.3    Brenner, B.4
  • 4
    • 65849366758 scopus 로고    scopus 로고
    • Microparticles bearing tissue factor and tissue factor pathway inhibitor in gestational vascular complications
    • Aharon, A., Katzenell, S., Tamari, T. & Brenner, B. (2009) Microparticles bearing tissue factor and tissue factor pathway inhibitor in gestational vascular complications. Journal of Thrombosis and Haemostasis, 7, 1047-1050.
    • (2009) Journal of Thrombosis and Haemostasis , vol.7 , pp. 1047-1050
    • Aharon, A.1    Katzenell, S.2    Tamari, T.3    Brenner, B.4
  • 5
    • 33751253494 scopus 로고    scopus 로고
    • Maternal-fetal conditions necessitating a medical intervention resulting in preterm birth
    • Ananth, C.V. & Vintzileos, A.M. (2006) Maternal-fetal conditions necessitating a medical intervention resulting in preterm birth. American Journal of Obstetrics and Gynecology, 195, 1557-1563.
    • (2006) American Journal of Obstetrics and Gynecology , vol.195 , pp. 1557-1563
    • Ananth, C.V.1    Vintzileos, A.M.2
  • 6
    • 33644669545 scopus 로고    scopus 로고
    • Late sporadic miscarriage is associated with abnormalities in spiral artery transformation and trophoblast invasion
    • Ball, E., Bulmer, J.N., Ayis, S., Lyall, F. & Robson, S.C. (2006) Late sporadic miscarriage is associated with abnormalities in spiral artery transformation and trophoblast invasion. Journal of Pathology, 208, 535-542.
    • (2006) Journal of Pathology , vol.208 , pp. 535-542
    • Ball, E.1    Bulmer, J.N.2    Ayis, S.3    Lyall, F.4    Robson, S.C.5
  • 7
    • 84856809942 scopus 로고    scopus 로고
    • VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    • Bates, S.M., Greer, I.A., Middeldorp, S., Veenstra, D.L., Prabulos, A.M. & Vandvik, P.O. (2012) VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest, 141(Suppl. 2), e691S-e736S.
    • (2012) Chest , vol.141 , Issue.SUPPL. 2
    • Bates, S.M.1    Greer, I.A.2    Middeldorp, S.3    Veenstra, D.L.4    Prabulos, A.M.5    Vandvik, P.O.6
  • 10
    • 0034100593 scopus 로고    scopus 로고
    • Gestational outcome in thrombophilic women with recurrent pregnancy loss treated by enoxaparin
    • Brenner, B., Hoffman, R., Blumenfeld, Z., Weiner, Z. & Younis, J.S. (2000) Gestational outcome in thrombophilic women with recurrent pregnancy loss treated by enoxaparin. Thrombosis and Haemostasis, 83, 693-697.
    • (2000) Thrombosis and Haemostasis , vol.83 , pp. 693-697
    • Brenner, B.1    Hoffman, R.2    Blumenfeld, Z.3    Weiner, Z.4    Younis, J.S.5
  • 11
    • 20844443510 scopus 로고    scopus 로고
    • Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study
    • Brenner, B., Hoffman, R., Carp, H., Dulitsky, M. & Younis, J. (2005a) Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study. Journal of Thrombosis and Haemostasis, 3, 227-229.
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , pp. 227-229
    • Brenner, B.1    Hoffman, R.2    Carp, H.3    Dulitsky, M.4    Younis, J.5
  • 12
    • 24944525788 scopus 로고    scopus 로고
    • Effects of enoxaparin on late pregnancy complications and neonatal outcome in women with recurrent pregnancy loss and thrombophilia: results from the Live-Enox study
    • Brenner, B., Bar, J., Ellis, M., Yarom, I., Yohai, D. & Samueloff, A. (2005b) Effects of enoxaparin on late pregnancy complications and neonatal outcome in women with recurrent pregnancy loss and thrombophilia: results from the Live-Enox study. Fertility and Sterility, 84, 770-773.
    • (2005) Fertility and Sterility , vol.84 , pp. 770-773
    • Brenner, B.1    Bar, J.2    Ellis, M.3    Yarom, I.4    Yohai, D.5    Samueloff, A.6
  • 14
    • 0141503825 scopus 로고    scopus 로고
    • Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia
    • Carp, H., Dolitzky, M. & Inbal, A. (2003) Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia. Journal of Thrombosis and Haemostasis, 1, 433-438.
    • (2003) Journal of Thrombosis and Haemostasis , vol.1 , pp. 433-438
    • Carp, H.1    Dolitzky, M.2    Inbal, A.3
  • 16
    • 84870888658 scopus 로고    scopus 로고
    • Mechanisms of implantation: strategies for successful pregnancy
    • Cha, J., Sun, X. & Dey, S.K. (2012) Mechanisms of implantation: strategies for successful pregnancy. Nature Medicine, 18, 1754-1767.
    • (2012) Nature Medicine , vol.18 , pp. 1754-1767
    • Cha, J.1    Sun, X.2    Dey, S.K.3
  • 18
    • 77951714717 scopus 로고    scopus 로고
    • SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage
    • Scottish Pregnancy Intervention Study (SPIN) collaborators. .
    • Clark, P., Walker, I.D., Langhorne, P., Crichton, L., Thomson, A., Greaves, M., Whyte, S., Greer, I.A. & Scottish Pregnancy Intervention Study (SPIN) collaborators. (2010) SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage. Blood, 115, 4162-4167.
    • (2010) Blood , vol.115 , pp. 4162-4167
    • Clark, P.1    Walker, I.D.2    Langhorne, P.3    Crichton, L.4    Thomson, A.5    Greaves, M.6    Whyte, S.7    Greer, I.A.8
  • 19
    • 84855297285 scopus 로고    scopus 로고
    • Effect of Low Molecular Weight Heparins (LMWHs) on antiphospholipid Antibodies (aPL)-mediated inhibition of endometrial angiogenesis
    • D'Ippolito, S., Marana, R., Di Nicuolo, F., Castellani, R., Veglia, M., Stinson, J., Scambia, G. & Di Simone, N. (2012) Effect of Low Molecular Weight Heparins (LMWHs) on antiphospholipid Antibodies (aPL)-mediated inhibition of endometrial angiogenesis. PLoS ONE, 7, e29660.
    • (2012) PLoS ONE , vol.7
    • D'Ippolito, S.1    Marana, R.2    Di Nicuolo, F.3    Castellani, R.4    Veglia, M.5    Stinson, J.6    Scambia, G.7    Di Simone, N.8
  • 20
    • 84891656268 scopus 로고    scopus 로고
    • Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction
    • Art. No.: CD006780. DOI: 10.1002/14651858.CD006780.pub3
    • Dodd, J.M., McLeod, A., Windrim, R.C. & Kingdom, J. (2013) Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction. The Cochrane Database of Systematic Reviews, (7), Art. No.: CD006780. DOI: 10.1002/14651858.CD006780.pub3
    • (2013) The Cochrane Database of Systematic Reviews , Issue.7
    • Dodd, J.M.1    McLeod, A.2    Windrim, R.C.3    Kingdom, J.4
  • 21
    • 80855165750 scopus 로고    scopus 로고
    • Heparin promotes soluble VEGF receptor expression in human placental villi to impair endothelial VEGF signaling
    • Drewlo, S., Levytska, K., Sobel, M., Baczyk, D., Lye, S.J. & Kingdom, J.C. (2011) Heparin promotes soluble VEGF receptor expression in human placental villi to impair endothelial VEGF signaling. Journal of Thrombosis and Haemostasis, 9, 2486-2497.
    • (2011) Journal of Thrombosis and Haemostasis , vol.9 , pp. 2486-2497
    • Drewlo, S.1    Levytska, K.2    Sobel, M.3    Baczyk, D.4    Lye, S.J.5    Kingdom, J.C.6
  • 22
    • 34249034723 scopus 로고    scopus 로고
    • Antiplatelet agents for preventing pre-eclampsia and its complications
    • Art. No.: CD004659. DOI: 10.1002/14651858.CD004659.pub2
    • Duley, L., Henderson-Smart, D.J., Meher, S. & King, J.F. (2007) Antiplatelet agents for preventing pre-eclampsia and its complications. The Cochrane Database of Systematic Reviews, (2), Art. No.: CD004659. DOI: 10.1002/14651858.CD004659.pub2
    • (2007) The Cochrane Database of Systematic Reviews , Issue.2
    • Duley, L.1    Henderson-Smart, D.J.2    Meher, S.3    King, J.F.4
  • 23
    • 0034253540 scopus 로고    scopus 로고
    • Expression of tissue factor pathway inhibitor in human fetal and placental tissues
    • Edstrom, C.S., Calhoun, D.A. & Christensen, R.D. (2000) Expression of tissue factor pathway inhibitor in human fetal and placental tissues. Early Human Development, 59, 77-84.
    • (2000) Early Human Development , vol.59 , pp. 77-84
    • Edstrom, C.S.1    Calhoun, D.A.2    Christensen, R.D.3
  • 24
    • 84921705962 scopus 로고    scopus 로고
    • Prevention of recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulant
    • Art. No.: CD002859. DOI: 10.1002/14651858.CD002859.pub2
    • Empson, M., Lassere, M., Craig, J. & Scott, J. (2005) Prevention of recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulant. The Cochrane Database of Systematic Reviews, (2), Art. No.: CD002859. DOI: 10.1002/14651858.CD002859.pub2
    • (2005) The Cochrane Database of Systematic Reviews , Issue.2
    • Empson, M.1    Lassere, M.2    Craig, J.3    Scott, J.4
  • 25
    • 0036711316 scopus 로고    scopus 로고
    • Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment
    • Farquharson, R.G., Quenby, S. & Greaves, M. (2002) Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment. Obstetrics and Gynecology, 100, 408-413.
    • (2002) Obstetrics and Gynecology , vol.100 , pp. 408-413
    • Farquharson, R.G.1    Quenby, S.2    Greaves, M.3
  • 26
    • 84900484953 scopus 로고    scopus 로고
    • The evidence of the HAPPY trial is severely limited by the criteria and the methodology of recruitment. Blood. e-Letter, June 1, url
    • Ferrazzi, E. & Gris, J.C. (2012) The evidence of the HAPPY trial is severely limited by the criteria and the methodology of recruitment. Blood. e-Letter, June 1, http://bloodjournal.hematologylibrary.org/letters?first-index=21&hits=10.
    • (2012)
    • Ferrazzi, E.1    Gris, J.C.2
  • 27
    • 4344608887 scopus 로고    scopus 로고
    • The placental problem: linking abnormal cytotrophoblast differentiation to the maternal symptoms of preeclampsia
    • Fisher, S.J. (2004) The placental problem: linking abnormal cytotrophoblast differentiation to the maternal symptoms of preeclampsia. Reproductive Biology and Endocrinology, 2, 53.
    • (2004) Reproductive Biology and Endocrinology , vol.2 , pp. 53
    • Fisher, S.J.1
  • 29
    • 34247574200 scopus 로고    scopus 로고
    • Systemic inflammatory priming in normal pregnancy and preeclampsia: the role of circulating syncytiotrophoblast microparticles
    • Germain, S.J., Sacks, G.P., Sooranna, S.R., Sargent, I.L. & Redman, C.W. (2007) Systemic inflammatory priming in normal pregnancy and preeclampsia: the role of circulating syncytiotrophoblast microparticles. Journal of Immunology, 178, 5949-5956.
    • (2007) Journal of Immunology , vol.178 , pp. 5949-5956
    • Germain, S.J.1    Sacks, G.P.2    Sooranna, S.R.3    Sargent, I.L.4    Redman, C.W.5
  • 31
    • 33644695013 scopus 로고    scopus 로고
    • The role of aspirin versus aspirin and heparin in cases of recurrent abortions with raised anticardiolipin antibodies
    • Goel, N., Tuli, A. & Choudhry, R. (2006) The role of aspirin versus aspirin and heparin in cases of recurrent abortions with raised anticardiolipin antibodies. Medical Science Monitor, 12, CR132-CR136.
    • (2006) Medical Science Monitor , vol.12
    • Goel, N.1    Tuli, A.2    Choudhry, R.3
  • 32
    • 27944467137 scopus 로고    scopus 로고
    • Excess syncytiotrophoblast microparticle shedding is a feature of early-onset pre-eclampsia, but not normotensive intrauterine growth restriction
    • Goswami, D., Tannetta, D.S., Magee, L.A., Fuchisawa, A., Redman, C.W., Sargent, I.L. & von Dadelszen, P. (2006) Excess syncytiotrophoblast microparticle shedding is a feature of early-onset pre-eclampsia, but not normotensive intrauterine growth restriction. Placenta, 27, 56-61.
    • (2006) Placenta , vol.27 , pp. 56-61
    • Goswami, D.1    Tannetta, D.S.2    Magee, L.A.3    Fuchisawa, A.4    Redman, C.W.5    Sargent, I.L.6    von Dadelszen, P.7
  • 33
    • 59449099388 scopus 로고    scopus 로고
    • Low molecular weight heparin for pregnancy complications?
    • Greer, I.A. (2009) Low molecular weight heparin for pregnancy complications? Thrombosis Research, 123(Suppl. 3), S22-S25.
    • (2009) Thrombosis Research , vol.123 , Issue.SUPPL. 3
    • Greer, I.A.1
  • 34
    • 22144466236 scopus 로고    scopus 로고
    • Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy
    • Greer, I.A. & Nelson-Piercy, C. (2005) Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy. Blood, 106, 401-407.
    • (2005) Blood , vol.106 , pp. 401-407
    • Greer, I.A.1    Nelson-Piercy, C.2
  • 35
    • 65549130403 scopus 로고    scopus 로고
    • Thrombophilia and pregnancy loss: cause or association
    • Gris, J.C. (2009) Thrombophilia and pregnancy loss: cause or association. Thrombosis Research, 123(Suppl. 2), S105-S110.
    • (2009) Thrombosis Research , vol.123 , Issue.SUPPL. 2
    • Gris, J.C.1
  • 36
    • 0005517354 scopus 로고    scopus 로고
    • Case-control study of the frequency of thrombophilic disorders in couples with late fetal loss and no thrombotic antecedent-the Nimes Obstetricians and Haematologists Study5 (NOHA5)
    • Gris, J.C., Quéré, I., Monpeyroux, F., Mercier, E., Ripart-Neveu, S., Tailland, M.L., Hoffet, M., Berlan, J., Daurès, J.P. & Marès, P. (1999) Case-control study of the frequency of thrombophilic disorders in couples with late fetal loss and no thrombotic antecedent-the Nimes Obstetricians and Haematologists Study5 (NOHA5). Thrombosis and Haemostasis, 81, 891-899.
    • (1999) Thrombosis and Haemostasis , vol.81 , pp. 891-899
    • Gris, J.C.1    Quéré, I.2    Monpeyroux, F.3    Mercier, E.4    Ripart-Neveu, S.5    Tailland, M.L.6    Hoffet, M.7    Berlan, J.8    Daurès, J.P.9    Marès, P.10
  • 39
    • 82555195546 scopus 로고    scopus 로고
    • Addition of enoxaparin to aspirin for the secondary prevention of placental vascular complications in women with severe pre-eclampsia. The pilot randomised controlled NOH-PE trial
    • Gris, J.C., Chauleur, C., Molinari, N., Mares, P., Fabbro-Peray, P., Quéré, I., Lefrant, J.Y., Haddad, B. & Dauzat, M. (2011) Addition of enoxaparin to aspirin for the secondary prevention of placental vascular complications in women with severe pre-eclampsia. The pilot randomised controlled NOH-PE trial. Thrombosis and Haemostasis, 106, 1053-1061.
    • (2011) Thrombosis and Haemostasis , vol.106 , pp. 1053-1061
    • Gris, J.C.1    Chauleur, C.2    Molinari, N.3    Mares, P.4    Fabbro-Peray, P.5    Quéré, I.6    Lefrant, J.Y.7    Haddad, B.8    Dauzat, M.9
  • 40
    • 0037044806 scopus 로고    scopus 로고
    • Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality
    • Gu, J.M., Crawley, J.T., Ferrell, G., Zhang, F., Li, W., Esmon, N.L. & Esmon, C.T. (2002) Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality. Journal of Biological Chemistry, 277, 43335-43343.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 43335-43343
    • Gu, J.M.1    Crawley, J.T.2    Ferrell, G.3    Zhang, F.4    Li, W.5    Esmon, N.L.6    Esmon, C.T.7
  • 42
    • 0346992324 scopus 로고    scopus 로고
    • The contribution of placental oxidative stress to early pregnancy failure
    • Hempstock, J., Jauniaux, E., Greenwold, N. & Burton, G.J. (2003) The contribution of placental oxidative stress to early pregnancy failure. Human Pathology, 34, 1265-1275.
    • (2003) Human Pathology , vol.34 , pp. 1265-1275
    • Hempstock, J.1    Jauniaux, E.2    Greenwold, N.3    Burton, G.J.4
  • 45
    • 0026593425 scopus 로고
    • Low molecular weight heparin
    • Hirsh, J. & Levine, M.N. (1992) Low molecular weight heparin. Blood, 79, 1-17.
    • (1992) Blood , vol.79 , pp. 1-17
    • Hirsh, J.1    Levine, M.N.2
  • 46
    • 0032936444 scopus 로고    scopus 로고
    • Expression of tissue type and urokinase type plasminogen activators as well as plasminogen activator inhibitor type-1 and type-2 in human and rhesus monkey placenta
    • Hu, Z.Y., Liu, Y.X., Liu, K., Byrne, S., Ny, T., Feng, Q. & Ockleford, C.D. (1999) Expression of tissue type and urokinase type plasminogen activators as well as plasminogen activator inhibitor type-1 and type-2 in human and rhesus monkey placenta. Journal of Anatomy, 194, 183-195.
    • (1999) Journal of Anatomy , vol.194 , pp. 183-195
    • Hu, Z.Y.1    Liu, Y.X.2    Liu, K.3    Byrne, S.4    Ny, T.5    Feng, Q.6    Ockleford, C.D.7
  • 47
    • 0037408297 scopus 로고    scopus 로고
    • Demonstration of a tissue factor pathway inhibitor 2 messenger RNA synthesis by pure villous cytotrophoblast cells isolated from term human placentas
    • Hube, F., Reverdiau, P., Lochmann, S., Trassard, S., Thibault, G. & Gruel, Y. (2003) Demonstration of a tissue factor pathway inhibitor 2 messenger RNA synthesis by pure villous cytotrophoblast cells isolated from term human placentas. Biology of Reproduction, 68, 1888-1894.
    • (2003) Biology of Reproduction , vol.68 , pp. 1888-1894
    • Hube, F.1    Reverdiau, P.2    Lochmann, S.3    Trassard, S.4    Thibault, G.5    Gruel, Y.6
  • 49
    • 1242271321 scopus 로고    scopus 로고
    • Secretion of tumor necrosis factor-alpha from human placental tissues induced by hypoxia-reoxygenation causes endothelial cell activation in vitro: a potential mediator of the inflammatory response in preeclampsia
    • Hung, T.H., Charnock-Jones, D.S., Skepper, J.N. & Burton, G.J. (2004) Secretion of tumor necrosis factor-alpha from human placental tissues induced by hypoxia-reoxygenation causes endothelial cell activation in vitro: a potential mediator of the inflammatory response in preeclampsia. American Journal of Pathology, 164, 1049-1061.
    • (2004) American Journal of Pathology , vol.164 , pp. 1049-1061
    • Hung, T.H.1    Charnock-Jones, D.S.2    Skepper, J.N.3    Burton, G.J.4
  • 52
    • 84865266022 scopus 로고    scopus 로고
    • Characterization of negatively charged phospholipids and cell origin of microparticles in women with gestational vascular complications
    • Katzenell, S., Shomer, E., Zipori, Y., Zylberfisz, A., Brenner, B. & Aharon, A. (2012) Characterization of negatively charged phospholipids and cell origin of microparticles in women with gestational vascular complications. Thrombosis Research, 130, 479-484.
    • (2012) Thrombosis Research , vol.130 , pp. 479-484
    • Katzenell, S.1    Shomer, E.2    Zipori, Y.3    Zylberfisz, A.4    Brenner, B.5    Aharon, A.6
  • 53
    • 84858283382 scopus 로고    scopus 로고
    • Guidelines on the investigation and management of antiphospholipid syndrome
    • British Committee for Standards in Haematology. .
    • Keeling, D., Mackie, I., Moore, G.W., Greer, I.A., Greaves, M. & British Committee for Standards in Haematology. (2012) Guidelines on the investigation and management of antiphospholipid syndrome. British Journal of Haematology, 157, 47-58.
    • (2012) British Journal of Haematology , vol.157 , pp. 47-58
    • Keeling, D.1    Mackie, I.2    Moore, G.W.3    Greer, I.A.4    Greaves, M.5
  • 55
    • 0029934389 scopus 로고    scopus 로고
    • Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone
    • Kutteh, W.H. (1996) Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone. American Journal of Obstetrics and Gynecology, 174, 1584-1589.
    • (1996) American Journal of Obstetrics and Gynecology , vol.174 , pp. 1584-1589
    • Kutteh, W.H.1
  • 57
    • 80052225210 scopus 로고    scopus 로고
    • Assessment of endometrial receptivity
    • Lessey, B.A. (2011) Assessment of endometrial receptivity. Fertility and Sterility, 96, 522-529.
    • (2011) Fertility and Sterility , vol.96 , pp. 522-529
    • Lessey, B.A.1
  • 58
    • 27144449028 scopus 로고    scopus 로고
    • Extraembryonic expression of EPCR is essential for embryonic viability
    • Li, W., Zheng, X., Gu, J.M., Ferrell, G.L., Brady, M., Esmon, N.L. & Esmon, C.T. (2005) Extraembryonic expression of EPCR is essential for embryonic viability. Blood, 106, 2716-2722.
    • (2005) Blood , vol.106 , pp. 2716-2722
    • Li, W.1    Zheng, X.2    Gu, J.M.3    Ferrell, G.L.4    Brady, M.5    Esmon, N.L.6    Esmon, C.T.7
  • 61
    • 33846627840 scopus 로고    scopus 로고
    • The role of decidualization in regulating endometrial hemostasis during the menstrual cycle, gestation, and in pathological states
    • Lockwood, C.J., Krikun, G., Rahman, M., Caze, R., Buchwalder, L. & Schatz, F. (2007) The role of decidualization in regulating endometrial hemostasis during the menstrual cycle, gestation, and in pathological states. Seminars in Thrombosis and Hemostasis, 33, 111-117.
    • (2007) Seminars in Thrombosis and Hemostasis , vol.33 , pp. 111-117
    • Lockwood, C.J.1    Krikun, G.2    Rahman, M.3    Caze, R.4    Buchwalder, L.5    Schatz, F.6
  • 72
  • 73
    • 54449098367 scopus 로고    scopus 로고
    • The potential role of heparin in assisted conception
    • Nelson, S.M. & Greer, I.A. (2008) The potential role of heparin in assisted conception. Human Reproduction Update, 14, 623-645.
    • (2008) Human Reproduction Update , vol.14 , pp. 623-645
    • Nelson, S.M.1    Greer, I.A.2
  • 76
    • 33646256586 scopus 로고    scopus 로고
    • Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study
    • Nurk, E., Tell, G.S., Refsum, H., Ueland, P.M. & Vollset, S.E. (2006) Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study. Quarterly Journal of Medicine, 99, 289-298.
    • (2006) Quarterly Journal of Medicine , vol.99 , pp. 289-298
    • Nurk, E.1    Tell, G.S.2    Refsum, H.3    Ueland, P.M.4    Vollset, S.E.5
  • 78
    • 33750993762 scopus 로고    scopus 로고
    • Association between antiphospholipid antibodies and recurrent fetal loss in women without autoimmune disease: a metaanalysis
    • Opatrny, L., David, M., Kahn, S.R., Shrier, I. & Rey, E. (2006) Association between antiphospholipid antibodies and recurrent fetal loss in women without autoimmune disease: a metaanalysis. Journal of Rheumatology, 33, 2214-2221.
    • (2006) Journal of Rheumatology , vol.33 , pp. 2214-2221
    • Opatrny, L.1    David, M.2    Kahn, S.R.3    Shrier, I.4    Rey, E.5
  • 84
    • 33747050669 scopus 로고    scopus 로고
    • Recurrent miscarriage
    • Rai, R. & Regan, L. (2006) Recurrent miscarriage. Lancet, 368, 601-611.
    • (2006) Lancet , vol.368 , pp. 601-611
    • Rai, R.1    Regan, L.2
  • 85
    • 0031022366 scopus 로고    scopus 로고
    • Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)
    • Rai, R., Cohen, H., Dave, M. & Regan, L. (1997) Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies). British medical Journal, 314, 253-257.
    • (1997) British medical Journal , vol.314 , pp. 253-257
    • Rai, R.1    Cohen, H.2    Dave, M.3    Regan, L.4
  • 86
    • 0035017316 scopus 로고    scopus 로고
    • Factor V Leiden and acquired activated protein C resistance among 1000 women with recurrent miscarriage
    • Rai, R., Shlebak, A., Cohen, H., Backos, M., Holmes, Z., Marriott, K. & Regan, L. (2001) Factor V Leiden and acquired activated protein C resistance among 1000 women with recurrent miscarriage. Human Reproduction, 16, 961-965.
    • (2001) Human Reproduction , vol.16 , pp. 961-965
    • Rai, R.1    Shlebak, A.2    Cohen, H.3    Backos, M.4    Holmes, Z.5    Marriott, K.6    Regan, L.7
  • 87
    • 34948903311 scopus 로고    scopus 로고
    • Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury
    • Redecha, P., Tilley, R., Tencati, M., Salmon, J.E., Kirchhofer, D., Mackman, N. & Girardi, G. (2007) Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury. Blood, 110, 2423-2431.
    • (2007) Blood , vol.110 , pp. 2423-2431
    • Redecha, P.1    Tilley, R.2    Tencati, M.3    Salmon, J.E.4    Kirchhofer, D.5    Mackman, N.6    Girardi, G.7
  • 88
    • 65449130085 scopus 로고    scopus 로고
    • Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury
    • Redecha, P., van Rooijen, N., Torry, D. & Girardi, G. (2009) Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury. Blood, 113, 4101-4109.
    • (2009) Blood , vol.113 , pp. 4101-4109
    • Redecha, P.1    van Rooijen, N.2    Torry, D.3    Girardi, G.4
  • 93
    • 84860323582 scopus 로고    scopus 로고
    • Early administration of low-dose aspirin for the prevention of preterm and term preeclampsia: a systematic review and meta-analysis
    • Roberge, S., Villa, P., Nicolaides, K., Giguere, Y., Vainio, M., Bakthi, A., Ebrashy, A. & Bujold, E. (2012b) Early administration of low-dose aspirin for the prevention of preterm and term preeclampsia: a systematic review and meta-analysis. Fetal Diagnosis and Therapy, 31, 141-146.
    • (2012) Fetal Diagnosis and Therapy , vol.31 , pp. 141-146
    • Roberge, S.1    Villa, P.2    Nicolaides, K.3    Giguere, Y.4    Vainio, M.5    Bakthi, A.6    Ebrashy, A.7    Bujold, E.8
  • 95
    • 77955027422 scopus 로고    scopus 로고
    • The association of factor V leiden and prothrombin gene mutation and placenta-mediated pregnancy complications: a systematic review and meta-analysis of prospective cohort studies
    • Rodger, M.A., Betancourt, M.T., Clark, P., Lindqvist, P.G., Dizon-Townson, D., Said, J., Seligsohn, U., Carrier, M., Salomon, O. & Greer, I.A. (2010) The association of factor V leiden and prothrombin gene mutation and placenta-mediated pregnancy complications: a systematic review and meta-analysis of prospective cohort studies. PLoS Medicine, 7, e1000292.
    • (2010) PLoS Medicine , vol.7
    • Rodger, M.A.1    Betancourt, M.T.2    Clark, P.3    Lindqvist, P.G.4    Dizon-Townson, D.5    Said, J.6    Seligsohn, U.7    Carrier, M.8    Salomon, O.9    Greer, I.A.10
  • 98
    • 57949106754 scopus 로고    scopus 로고
    • Laboratory classification categories and pregnancy outcome in patients with primary antiphospholipid syndrome prescribed antithrombotic therapy
    • Ruffatti, A., Tonello, M., Cavazzana, A., Bagatella, P. & Pengo, V. (2009) Laboratory classification categories and pregnancy outcome in patients with primary antiphospholipid syndrome prescribed antithrombotic therapy. Thrombosis Research, 123, 482-487.
    • (2009) Thrombosis Research , vol.123 , pp. 482-487
    • Ruffatti, A.1    Tonello, M.2    Cavazzana, A.3    Bagatella, P.4    Pengo, V.5
  • 100
    • 33646462158 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I antibodies are associated with pregnancy loss in women with the lupus anticoagulant
    • Sailer, T., Zoghlami, C., Kurz, C., Rumpold, H., Quehenberger, P. & Pabinger, I. (2006) Anti-beta2-glycoprotein I antibodies are associated with pregnancy loss in women with the lupus anticoagulant. Thrombosis and Haemostasis, 95, 796-801.
    • (2006) Thrombosis and Haemostasis , vol.95 , pp. 796-801
    • Sailer, T.1    Zoghlami, C.2    Kurz, C.3    Rumpold, H.4    Quehenberger, P.5    Pabinger, I.6
  • 101
    • 0038714896 scopus 로고    scopus 로고
    • Activation of complement mediates antiphospholipid antibody-induced pregnancy loss
    • Salmon, J.E., Girardi, G. & Holers, V.M. (2003) Activation of complement mediates antiphospholipid antibody-induced pregnancy loss. Lupus, 12, 535.
    • (2003) Lupus , vol.12 , pp. 535
    • Salmon, J.E.1    Girardi, G.2    Holers, V.M.3
  • 103
    • 27844499722 scopus 로고    scopus 로고
    • Modulation of systemic hemostatic parameters by enoxaparin during gestation in women with thrombophilia and pregnancy loss
    • Sarig, G., Blumenfeld, Z., Leiba, R., Lanir, N. & Brenner, B. (2005) Modulation of systemic hemostatic parameters by enoxaparin during gestation in women with thrombophilia and pregnancy loss. Thrombosis and Haemostasis, 94, 980-985.
    • (2005) Thrombosis and Haemostasis , vol.94 , pp. 980-985
    • Sarig, G.1    Blumenfeld, Z.2    Leiba, R.3    Lanir, N.4    Brenner, B.5
  • 104
    • 33846930928 scopus 로고    scopus 로고
    • Excessive complement activation is associated with placental injury in patients with antiphospholipid antibodies
    • Shamonki, J.M., Salmon, J.E., Hyjek, E. & Baergen, R.N. (2007) Excessive complement activation is associated with placental injury in patients with antiphospholipid antibodies. American Journal of Obstetrics and Gynecology, 196, 167.e1-167.e5.
    • (2007) American Journal of Obstetrics and Gynecology , vol.196
    • Shamonki, J.M.1    Salmon, J.E.2    Hyjek, E.3    Baergen, R.N.4
  • 105
    • 84886417281 scopus 로고    scopus 로고
    • Microvesicles of women with gestational hypertension and preeclampsia affect human trophoblast fate and endothelial function
    • Shomer, E., Katzenell, S., Zipori, Y., Sammour, R.N., Isermann, B., Brenner, B. & Aharon, A. (2013) Microvesicles of women with gestational hypertension and preeclampsia affect human trophoblast fate and endothelial function. Hypertension, 62, 893-898.
    • (2013) Hypertension , vol.62 , pp. 893-898
    • Shomer, E.1    Katzenell, S.2    Zipori, Y.3    Sammour, R.N.4    Isermann, B.5    Brenner, B.6    Aharon, A.7
  • 114
    • 84855360555 scopus 로고    scopus 로고
    • Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia: the FRUIT-RCT
    • de Vries, J.I., van Pampus, M.G., Hague, W.M., Bezemer, P.D. & Joosten, J.H. (2012) Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia: the FRUIT-RCT. Journal of Thrombosis and Haemostasis, 10, 64-72.
    • (2012) Journal of Thrombosis and Haemostasis , vol.10 , pp. 64-72
    • de Vries, J.I.1    van Pampus, M.G.2    Hague, W.M.3    Bezemer, P.D.4    Joosten, J.H.5
  • 115
    • 0036025255 scopus 로고    scopus 로고
    • Increased endothelial thrombomodulin (TM) expression in pregnancies complicated by IUGR
    • Wienhard, J., Bielska, B., Munstedt, K., Lang, U. & Zygmunt, M. (2002) Increased endothelial thrombomodulin (TM) expression in pregnancies complicated by IUGR. Journal of Perinatal Medicine, 30, 322-328.
    • (2002) Journal of Perinatal Medicine , vol.30 , pp. 322-328
    • Wienhard, J.1    Bielska, B.2    Munstedt, K.3    Lang, U.4    Zygmunt, M.5
  • 117
    • 39149085324 scopus 로고    scopus 로고
    • Genetic risk factors for placental abruption: a HuGE review and meta-analysis
    • Zdoukopoulos, N. & Zintzaras, E. (2008) Genetic risk factors for placental abruption: a HuGE review and meta-analysis. Epidemiology, 19, 309-323.
    • (2008) Epidemiology , vol.19 , pp. 309-323
    • Zdoukopoulos, N.1    Zintzaras, E.2


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