Pulsatile exposure to simulated reflux leads to changes in gene expression in a 3D model of oesophageal mucosa

International Journal of Experimental Pathology

Volumn 95, Issue 3, 2014, Pages 216-228

  Green, Nicola H ^a   Nicholls, Zoe ^a   Heath, Paul R ^b   Cooper Knock, Jonathan ^b   Corfe, Bernard M ^a   Macneil, Sheila ^a   Bury, Jonathan P ^c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Acid; Barrett's metaplasia; HNF4alpha; Oesophageal adenocarcinoma; Reflux; Taurochenodeoxycholate; Tissue engineering

Indexed keywords

BILE SALT; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TAUROCHENODEOXYCHOLIC ACID; TRANSCRIPTION FACTOR CDX1; TRANSCRIPTION FACTOR CDX2;

ARTICLE; BARRET METAPLASIA; CELL ACTIVATION; CELL ADHESION; CELL COMPONENT; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE COURSE; EPITHELIUM CELL; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGUS MUCOSA; GASTROESOPHAGEAL REFLUX; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; MICROARRAY ANALYSIS; PH; PRIORITY JOURNAL; WNT SIGNALING PATHWAY;

ACID; BARRETT'S METAPLASIA; HNF4ALPHA; OESOPHAGEAL ADENOCARCINOMA; REFLUX; TAUROCHENODEOXYCHOLATE; TISSUE ENGINEERING;

ADENOCARCINOMA; BARRETT ESOPHAGUS; BILE ACIDS AND SALTS; BILE REFLUX; CELL LINE; CELLS, CULTURED; EPITHELIAL CELLS; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; GASTROESOPHAGEAL REFLUX; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; HYDROGEN-ION CONCENTRATION; MUCOUS MEMBRANE; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN ISOFORMS; TAUROCHENODEOXYCHOLIC ACID; TRANSCRIPTION FACTORS;

EID: 84900514549     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/iep.12083     Document Type: Article

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