High-throughput sequencing for the identification of NOTCH1 mutations in early stage chronic lymphocytic leukaemia: Biological and clinical implications

British Journal of Haematology

Volumn 165, Issue 5, 2014, Pages 629-639

  Lionetti, Marta ^a,b   Fabris, Sonia ^a,b   Cutrona, Giovanna ^c   Agnelli, Luca ^a,b   Ciardullo, Carmela ^d   Matis, Serena ^c   Ciceri, Gabriella ^a,b   Colombo, Monica ^c   Maura, Francesco ^a,b   Mosca, Laura ^a,b   Gentile, Massimo ^e   Recchia, Anna G ^e   Ilariucci, Fiorella ^f   Musolino, Caterina ^g   Molica, Stefano ^h   Di Raimondo, Francesco ⁱ   Cortelezzi, Agostino ^a,b   Rossi, Davide ^d   Gaidano, Gianluca ^d   Morabito, Fortunato ^e   Ferrarini, Manlio ^c   Neri, Antonino ^a,b   more..

^a UNIVERSITY OF MILAN   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d Amedeo Avogadro University   (Italy)

^e Direzione Scientifica IRCCS San Martino IST ^*  (Italy)

^f Division of Haematology   (Italy)

^g UNIVERSITY OF MESSINA   (Italy)

^h PUGLIESE CIACCIO HOSPITAL   (Italy)

ⁱ UNIVERSITY OF CATANIA   (Italy)

Author keywords

Chronic lymphocytic leukaemia; Monoclonal B cell lymphocytosis; Next generation sequencing; NOTCH1; Prognosis

Indexed keywords

NOTCH1 RECEPTOR; NOTCH1 PROTEIN, HUMAN; TUMOR MARKER; TUMOR PROTEIN;

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; EARLY CANCER; FEMALE; GENE DELETION; GENE IDENTIFICATION; GENE MUTATION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IGHV GENE; MAJOR CLINICAL STUDY; MALE; MONOCLONAL B CELL LYMPHOCYTOSIS; MULTICENTER STUDY; MUTATOR GENE; NOTCH1 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; SENSITIVITY ANALYSIS; TUMOR GENE; B LYMPHOCYTE; CLINICAL TRIAL; GENE FREQUENCY; GENETICS; KAPLAN MEIER METHOD; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LYMPHOCYTOSIS; MIDDLE AGED; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROCEDURES; PROGNOSIS;

ADULT; AGED; B-LYMPHOCYTES; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; KAPLAN-MEIER ESTIMATE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LYMPHOCYTOSIS; MALE; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; NEOPLASM STAGING; POLYMERASE CHAIN REACTION; PROGNOSIS; RECEPTOR, NOTCH1; TUMOR MARKERS, BIOLOGICAL;

EID: 84900487705     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12800     Document Type: Article

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