Glatiramer acetate reverses cognitive deficits from cranial-irradiated rat by inducing hippocampal neurogenesis

Journal of Neuroimmunology

Volumn 271, Issue 1-2, 2014, Pages 1-7

  He, Fen ^a,b   Zou, Jun Tao ^c   Zhou, Qiong Fang ^b   Niu, Dao Li ^b   Jia, Wei Hua ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cognitive deficit; Cranial irradiation; Glatiramer; Hippocampus

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GAMMA INTERFERON; GLATIRAMER; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; HIPPOCAMPUS; IMMUNE RESPONSE; IMMUNOMODULATION; MALE; MICROGLIA; MORRIS WATER MAZE TEST; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKULL IRRADIATION; TH1 CELL; TH2 CELL; TRANSCRIPTION REGULATION;

COGNITIVE DEFICIT; CRANIAL IRRADIATION; GLATIRAMER; HIPPOCAMPUS;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CALCIUM-BINDING PROTEINS; COGNITION DISORDERS; CRANIAL IRRADIATION; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOSUPPRESSIVE AGENTS; MALE; MAZE LEARNING; MICROFILAMENT PROTEINS; NERVE TISSUE PROTEINS; NEUROGENESIS; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84900486528     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2014.03.015     Document Type: Article

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