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Volumn 16, Issue 3, 2014, Pages 265-278.e13

CTHRC1 acts as a prognostic factor and promotes invasiveness of gastrointestinal stromal tumors by activating Wnt/PCP-Rho signaling

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COLLAGEN TRIPLE HELIX REPEAT CONTAINING 1; IMATINIB; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; CTHRC1 PROTEIN, HUMAN; ONCOPROTEIN; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RAC1 PROTEIN; RAC1 PROTEIN, HUMAN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, HUMAN; SCLEROPROTEIN; WNT PROTEIN; WNT5A PROTEIN, HUMAN;

EID: 84900449416     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1016/j.neo.2014.03.001     Document Type: Article
Times cited : (85)

References (50)
  • 2
    • 84885793903 scopus 로고    scopus 로고
    • Expression and clinicopathological significance of CD9 in gastrointestinal stromal tumor
    • Yang H, Shen C, Zhang B, Chen H, Chen Z, and Chen J (2013). Expression and clinicopathological significance of CD9 in gastrointestinal stromal tumor. J Korean Med Sci 28, 1443-1448.
    • (2013) J Korean Med Sci , vol.28 , pp. 1443-1448
    • Yang, H.1    Shen, C.2    Zhang, B.3    Chen, H.4    Chen, Z.5    Chen, J.6
  • 3
    • 84882953092 scopus 로고    scopus 로고
    • Smooth muscles and stem cells of embryonic guts express KIT, PDGFRRA, CD34 and many other stem cell antigens: Suggestion that GIST arise from smooth muscles and gut stem cells
    • Terada T (2013). Smooth muscles and stem cells of embryonic guts express KIT, PDGFRRA, CD34 and many other stem cell antigens: suggestion that GIST arise from smooth muscles and gut stem cells. Int J Clin Exp Pathol 6, 1038-1045.
    • (2013) Int J Clin Exp Pathol , vol.6 , pp. 1038-1045
    • Terada, T.1
  • 6
    • 84877850694 scopus 로고    scopus 로고
    • SKP2 high expression, KIT exon 11 deletions, and gastrointestinal bleeding as predictors of poor prognosis in primary gastrointestinal stromal tumors
    • Lv A, Li Z, Tian X, Guan X, Zhao M, Dong B, and Hao C (2013). SKP2 high expression, KIT exon 11 deletions, and gastrointestinal bleeding as predictors of poor prognosis in primary gastrointestinal stromal tumors. PLoS One 8, e62951.
    • (2013) PLoS One , vol.8
    • Lv, A.1    Li, Z.2    Tian, X.3    Guan, X.4    Zhao, M.5    Dong, B.6    Hao, C.7
  • 7
    • 84893524660 scopus 로고    scopus 로고
    • Gene expression network analysis of ETV1 reveals KCTD10 as a novel prognostic biomarker in gastrointestinal stromal tumor
    • Kubota D, Yoshida A, Tsuda H, Suehara Y, Okubo T, Saito T, Orita H, Sato K, Taguchi T, and Yao T, et al (2013). Gene expression network analysis of ETV1 reveals KCTD10 as a novel prognostic biomarker in gastrointestinal stromal tumor. PLoS One 8, e73896.
    • (2013) PLoS One , vol.8
    • Kubota, D.1    Yoshida, A.2    Tsuda, H.3    Suehara, Y.4    Okubo, T.5    Saito, T.6    Orita, H.7    Sato, K.8    Taguchi, T.9    Yao, T.10
  • 8
    • 25144443610 scopus 로고    scopus 로고
    • Pathophysiology, diagnosis, and treatment of gastrointestinal stromal tumors
    • Shinomura Y, Kinoshita K, Tsutsui S, and Hirota S (2005). Pathophysiology, diagnosis, and treatment of gastrointestinal stromal tumors. J Gastroenterol 40, 775-780.
    • (2005) J Gastroenterol , vol.40 , pp. 775-780
    • Shinomura, Y.1    Kinoshita, K.2    Tsutsui, S.3    Hirota, S.4
  • 10
    • 84872892692 scopus 로고    scopus 로고
    • Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): An international, multicentre, randomised, placebo-controlled, phase 3 trial
    • Demetri GD, Reichardt P, Kang YK, Blay JY, Rutkowski P, Gelderblom H, Hohenberger P, Leahy M, von Mehren M, and Joensuu H, et al (2013). Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet 381, 295-302.
    • (2013) Lancet , vol.381 , pp. 295-302
    • Demetri, G.D.1    Reichardt, P.2    Kang, Y.K.3    Blay, J.Y.4    Rutkowski, P.5    Gelderblom, H.6    Hohenberger, P.7    Leahy, M.8    von Mehren, M.9    Joensuu, H.10
  • 11
    • 0035142836 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis
    • Miettinen M and Lasota J (2001). Gastrointestinal stromal tumors-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 438, 1-12.
    • (2001) Virchows Arch , vol.438 , pp. 1-12
    • Miettinen, M.1    Lasota, J.2
  • 13
    • 84880763495 scopus 로고    scopus 로고
    • Overexpression of CTHRC1 in Hepatocellular Carcinoma Promotes Tumor Invasion and Predicts Poor Prognosis
    • Chen YL, Wang TH, Hsu HC, Yuan RH, and Jeng YM (2013). Overexpression of CTHRC1 in Hepatocellular Carcinoma Promotes Tumor Invasion and Predicts Poor Prognosis. PloS One 8, e70324.
    • (2013) PloS One , vol.8
    • Chen, Y.L.1    Wang, T.H.2    Hsu, H.C.3    Yuan, R.H.4    Jeng, Y.M.5
  • 14
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: A dynamic niche in cancer progression
    • Lu P, Weaver VM, and Werb Z (2012). The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol 196, 395-406.
    • (2012) J Cell Biol , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 16
    • 13444272946 scopus 로고    scopus 로고
    • Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration
    • Pyagay P, Heroult M, Wang Q, Lehnert W, Belden J, Liaw L, Friesel RE, and Lindner V (2005). Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration. Circ Res 96, 261-268.
    • (2005) Circ Res , vol.96 , pp. 261-268
    • Pyagay, P.1    Heroult, M.2    Wang, Q.3    Lehnert, W.4    Belden, J.5    Liaw, L.6    Friesel, R.E.7    Lindner, V.8
  • 17
    • 46049083566 scopus 로고    scopus 로고
    • Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex
    • Yamamoto S, Nishimura O, Misaki K, Nishita M, Minami Y, Yonemura S, Tarui H, and Sasaki H (2008). Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev Cell 15, 23-36.
    • (2008) Dev Cell , vol.15 , pp. 23-36
    • Yamamoto, S.1    Nishimura, O.2    Misaki, K.3    Nishita, M.4    Minami, Y.5    Yonemura, S.6    Tarui, H.7    Sasaki, H.8
  • 18
    • 84874768331 scopus 로고    scopus 로고
    • Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells
    • Park EH, Kim S, Jo JY, Kim SJ, Hwang Y, Kim JM, Song SY, Lee DK, and Koh SS (2013). Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells. Carcinogenesis 34, 694-702.
    • (2013) Carcinogenesis , vol.34 , pp. 694-702
    • Park, E.H.1    Kim, S.2    Jo, J.Y.3    Kim, S.J.4    Hwang, Y.5    Kim, J.M.6    Song, S.Y.7    Lee, D.K.8    Koh, S.S.9
  • 19
    • 84863326886 scopus 로고    scopus 로고
    • CTHRC1 is upregulated by promoter demethylation and transforming growth factor-beta1 and may be associated with metastasis in human gastric cancer
    • Wang P, Wang YC, Chen XY, Shen ZY, Cao H, Zhang YJ, Yu J, Zhu JD, Lu YY, and Fang JY (2012). CTHRC1 is upregulated by promoter demethylation and transforming growth factor-beta1 and may be associated with metastasis in human gastric cancer. Cancer Sci 103, 1327-1333.
    • (2012) Cancer Sci , vol.103 , pp. 1327-1333
    • Wang, P.1    Wang, Y.C.2    Chen, X.Y.3    Shen, Z.Y.4    Cao, H.5    Zhang, Y.J.6    Yu, J.7    Zhu, J.D.8    Lu, Y.Y.9    Fang, J.Y.10
  • 20
    • 84880641254 scopus 로고    scopus 로고
    • CTHRC1 is associated with peritoneal carcinomatosis in colorectal cancer: A new predictor for prognosis
    • Tan F, Liu F, Liu H, Hu Y, Liu D, and Li G (2013). CTHRC1 is associated with peritoneal carcinomatosis in colorectal cancer: a new predictor for prognosis. Med Oncol 30, 473.
    • (2013) Med Oncol , vol.30 , pp. 473
    • Tan, F.1    Liu, F.2    Liu, H.3    Hu, Y.4    Liu, D.5    Li, G.6
  • 21
    • 50649085726 scopus 로고    scopus 로고
    • Risk stratification of patients diagnosed with gastrointestinal stromal tumor
    • Joensuu H (2008). Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum Pathol 39, 1411-1419.
    • (2008) Hum Pathol , vol.39 , pp. 1411-1419
    • Joensuu, H.1
  • 22
    • 80052963619 scopus 로고    scopus 로고
    • Validation of the Joensuu risk criteria for primary resectable gastrointestinal stromal tumour - the impact of tumour rupture on patient outcomes
    • Rutkowski P, Bylina E, Wozniak A, Nowecki ZI, Osuch C, Matlok M, Switaj T, Michej W, Wronski M, and Gluszek S, et al (2011). Validation of the Joensuu risk criteria for primary resectable gastrointestinal stromal tumour - the impact of tumour rupture on patient outcomes. Eur J Surg Oncol 37, 890-896.
    • (2011) Eur J Surg Oncol , vol.37 , pp. 890-896
    • Rutkowski, P.1    Bylina, E.2    Wozniak, A.3    Nowecki, Z.I.4    Osuch, C.5    Matlok, M.6    Switaj, T.7    Michej, W.8    Wronski, M.9    Gluszek, S.10
  • 24
    • 60349097313 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors (GISTs): A review
    • Steigen SE and Eide TJ (2009). Gastrointestinal stromal tumors (GISTs): a review. APMIS 117, 73-86.
    • (2009) APMIS , vol.117 , pp. 73-86
    • Steigen, S.E.1    Eide, T.J.2
  • 25
    • 0033772093 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Current diagnosis, biologic behavior, and management
    • Pidhorecky I, Cheney RT, Kraybill WG, and Gibbs JF (2000). Gastrointestinal stromal tumors: current diagnosis, biologic behavior, and management. Ann Surg Oncol 7, 705-712.
    • (2000) Ann Surg Oncol , vol.7 , pp. 705-712
    • Pidhorecky, I.1    Cheney, R.T.2    Kraybill, W.G.3    Gibbs, J.F.4
  • 26
    • 84885048347 scopus 로고    scopus 로고
    • GSTT1 copy number gain and ZNF overexpression are predictors of poor response to imatinib in gastrointestinal stromal tumors
    • Lee EJ, Kang G, Kang SW, Jang KT, Lee J, Park JO, Park CK, Sohn TS, Kim S, and Kim KM (2013). GSTT1 copy number gain and ZNF overexpression are predictors of poor response to imatinib in gastrointestinal stromal tumors. PLoS One 8, e77219.
    • (2013) PLoS One , vol.8
    • Lee, E.J.1    Kang, G.2    Kang, S.W.3    Jang, K.T.4    Lee, J.5    Park, J.O.6    Park, C.K.7    Sohn, T.S.8    Kim, S.9    Kim, K.M.10
  • 29
    • 84880169315 scopus 로고    scopus 로고
    • Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling
    • Miao CG, Yang YY, He X, Li XF, Huang C, Huang Y, Zhang L, Lv XW, Jin Y, and Li J (2013). Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling. Cell Signal 25, 2069-2078.
    • (2013) Cell Signal , vol.25 , pp. 2069-2078
    • Miao, C.G.1    Yang, Y.Y.2    He, X.3    Li, X.F.4    Huang, C.5    Huang, Y.6    Zhang, L.7    Lv, X.W.8    Jin, Y.9    Li, J.10
  • 31
    • 84859715721 scopus 로고    scopus 로고
    • Tumor microenvironment: A main actor in the metastasis process
    • Spano D and Zollo M (2012). Tumor microenvironment: a main actor in the metastasis process. Clin Exp Metastasis 29, 381-395.
    • (2012) Clin Exp Metastasis , vol.29 , pp. 381-395
    • Spano, D.1    Zollo, M.2
  • 32
    • 84870252814 scopus 로고    scopus 로고
    • The complex world of WNT receptor signalling
    • Niehrs C (2012). The complex world of WNT receptor signalling. Nat Rev Mol Cell Biol 13, 767-779.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 767-779
    • Niehrs, C.1
  • 33
    • 84885183994 scopus 로고    scopus 로고
    • Investigation of 3-aryl-pyrimido [5,4-e] [1,2,4]triazine-5,7-diones as small molecule antagonists of beta-catenin/TCF transcription
    • Zeller J, Turbiak AJ, Powelson IA, Lee S, Sun D, Showalter HD, and Fearon ER (2013). Investigation of 3-aryl-pyrimido [5,4-e] [1,2,4]triazine-5,7-diones as small molecule antagonists of beta-catenin/TCF transcription. Bioorg Med Chem Lett 23, 5814-5820.
    • (2013) Bioorg Med Chem Lett , vol.23 , pp. 5814-5820
    • Zeller, J.1    Turbiak, A.J.2    Powelson, I.A.3    Lee, S.4    Sun, D.5    Showalter, H.D.6    Fearon, E.R.7
  • 36
    • 78651070815 scopus 로고    scopus 로고
    • The Wnt5a/Ror2 noncanonical signaling pathway inhibits canonical Wnt signaling in K562 cells
    • Yuan Y, Niu CC, Deng G, Li ZQ, Pan J, Zhao C, Yang ZL, and Si WK (2011). The Wnt5a/Ror2 noncanonical signaling pathway inhibits canonical Wnt signaling in K562 cells. Int J Mol Med 27, 63-69.
    • (2011) Int J Mol Med , vol.27 , pp. 63-69
    • Yuan, Y.1    Niu, C.C.2    Deng, G.3    Li, Z.Q.4    Pan, J.5    Zhao, C.6    Yang, Z.L.7    Si, W.K.8
  • 37
    • 65349158233 scopus 로고    scopus 로고
    • Roles of noncanonical Wnt/PCP pathway genes in neuronal migration and neurulation in zebrafish
    • Wada H and Okamoto H (2009). Roles of noncanonical Wnt/PCP pathway genes in neuronal migration and neurulation in zebrafish. Zebrafish 6, 3-8.
    • (2009) Zebrafish , vol.6 , pp. 3-8
    • Wada, H.1    Okamoto, H.2
  • 38
    • 84868665485 scopus 로고    scopus 로고
    • Wnt regulation of planar cell polarity (PCP)
    • Gao B (2012). Wnt regulation of planar cell polarity (PCP). Curr Top Dev Biol 101, 263-295.
    • (2012) Curr Top Dev Biol , vol.101 , pp. 263-295
    • Gao, B.1
  • 39
    • 84867198093 scopus 로고    scopus 로고
    • Wnt5a potentiates TGF-beta signaling to promote colonic crypt regeneration after tissue injury
    • Miyoshi H, Ajima R, Luo CT, Yamaguchi TP, and Stappenbeck TS (2012). Wnt5a potentiates TGF-beta signaling to promote colonic crypt regeneration after tissue injury. Science 338, 108-113.
    • (2012) Science , vol.338 , pp. 108-113
    • Miyoshi, H.1    Ajima, R.2    Luo, C.T.3    Yamaguchi, T.P.4    Stappenbeck, T.S.5
  • 40
    • 33644698339 scopus 로고    scopus 로고
    • WNT/PCP signaling pathway and human cancer (review)
    • Katoh M (2005). WNT/PCP signaling pathway and human cancer (review). Oncol Rep 14, 1583-1588.
    • (2005) Oncol Rep , vol.14 , pp. 1583-1588
    • Katoh, M.1
  • 41
    • 79960839001 scopus 로고    scopus 로고
    • Roles of the small GTPases RhoA and Rac1 in cell behavior
    • Otey C, Goicoechea S, and Garcia-Mata R (2009). Roles of the small GTPases RhoA and Rac1 in cell behavior. F1000 Biol Rep 1, 4.
    • (2009) F1000 Biol Rep , vol.1 , pp. 4
    • Otey, C.1    Goicoechea, S.2    Garcia-Mata, R.3
  • 43
    • 3242699514 scopus 로고    scopus 로고
    • Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer
    • Kamai T, Yamanishi T, Shirataki H, Takagi K, Asami H, Ito Y, and Yoshida K (2004). Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer. Clin Cancer Res 10, 4799-4805.
    • (2004) Clin Cancer Res , vol.10 , pp. 4799-4805
    • Kamai, T.1    Yamanishi, T.2    Shirataki, H.3    Takagi, K.4    Asami, H.5    Ito, Y.6    Yoshida, K.7
  • 44
    • 84861325758 scopus 로고    scopus 로고
    • Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA
    • Deakin NO, Ballestrem C, and Turner CE (2012). Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA. PLoS One 7, e37990.
    • (2012) PLoS One , vol.e37990 , pp. 7
    • Deakin, N.O.1    Ballestrem, C.2    Turner, C.E.3
  • 45
    • 81055130119 scopus 로고    scopus 로고
    • Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia
    • Chauhan BK, Lou M, Zheng Y, and Lang RA (2011). Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc Natl Acad Sci U S A 108, 18289-18294.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 18289-18294
    • Chauhan, B.K.1    Lou, M.2    Zheng, Y.3    Lang, R.A.4
  • 46
    • 0029015774 scopus 로고
    • The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
    • Hill CS, Wynne J, and Treisman R (1995). The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81, 1159-1170.
    • (1995) Cell , vol.81 , pp. 1159-1170
    • Hill, C.S.1    Wynne, J.2    Treisman, R.3
  • 48
    • 78649729521 scopus 로고    scopus 로고
    • The role of ubiquitylation and degradation in RhoGTPase signalling
    • Nethe M and Hordijk PL (2010). The role of ubiquitylation and degradation in RhoGTPase signalling. J Cell Sci 123, 4011-4018.
    • (2010) J Cell Sci , vol.123 , pp. 4011-4018
    • Nethe, M.1    Hordijk, P.L.2


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