Roles for the mitogen-Activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13667-13679

  Shah, Suharsh ^a   King, Elizabeth M ^a   Chandrasekhar, Ambika ^a   Newton, Robert ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; HORMONES; NUCLEIC ACIDS; PHOSPHATASES;

ANTI-INFLAMMATORIES; FEEDBACK INHIBITION; GLUCOCORTICOID RECEPTOR; INFLAMMATORY GENE EXPRESSIONS; INFLAMMATORY GENES; MITOGEN ACTIVATED PROTEIN KINASE; MRNA EXPRESSION; THERAPEUTIC INDEX;

GENE EXPRESSION;

CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; CXCL3 CHEMOKINE; DEXAMETHASONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1;

ARTICLE; CCL2 GENE; CCL20 GENE; CONTROLLED STUDY; CSF2 GENE; CXCL1 GENE; CXCL2 GENE; CXCL3 GENE; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INHIBITION; FEEDBACK SYSTEM; GENE; GENE EXPRESSION; GENE INDUCTION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IL 6 GENE; IL 8 GENE; ISG20 GENE; OLR1 GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; PTGS2 GENE; SIGNAL TRANSDUCTION;

ANTI-INFLAMMATORY; CORTICOSTEROID; EPITHELIAL CELL; GENE REGULATION; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOIDS; INFLAMMATION; MAP KINASES (MAPKS); MAPK PHOSPHATASE 1 (MKP-1); NR3C1;

CELL LINE; CYCLOOXYGENASE 2; CYTOKINES; DEXAMETHASONE; DUAL SPECIFICITY PHOSPHATASE 1; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; INFLAMMATION; MAP KINASE SIGNALING SYSTEM;

EID: 84900433928     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.540799     Document Type: Article

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