Submicron-bubble-enhanced focused ultrasound for blood-brain barrier disruption and improved CNS drug delivery

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Fan, Ching Hsiang ^a   Liu, Hao Li ^b   Ting, Chien Yu ^a   Lee, Ya Hsuan ^a   Huang, Chih Ying ^b   Yan Jung, Ma ^b   Wei, Kuo Chen ^c   Yen, Tzu Chen ^c   Yeh, Chih Kuang ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CARMUSTINE; ALKYLATING AGENT; CONTRAST MEDIUM;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DAMAGE; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG SAFETY; ERYTHROCYTE; EXTRAVASATION; FOCUSED ULTRASOUND; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; IN VIVO STUDY; INERTIAL CAVITATION; MALE; MICROBUBBLE; NONHUMAN; OSCILLATION; PHYSICAL PHENOMENA; RAT; SUBMICRON BUBBLE; SUSCEPTIBILITY WEIGHTED IMAGING; ULTRASOUND; ANIMAL; BRAIN; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; REPRODUCIBILITY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BLOOD-BRAIN BARRIER; BRAIN; CARMUSTINE; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; MAGNETIC RESONANCE IMAGING; MALE; MICROBUBBLES; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SONICATION; ULTRASONICS;

EID: 84900423799     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096327     Document Type: Article

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