메뉴 건너뛰기




Volumn 8, Issue , 2014, Pages 447-457

Inhibition of B7-1 (CD80) by RhuDex® reduces lipopolysaccharide-mediated inflammation in human atherosclerotic lesions

Author keywords

Atherosclerosis; B7; CD86; Costimulation

Indexed keywords

B7 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN INHIBITOR; RHUDEX; THROMBOPLASTIN; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHEMOKINE; CYTOKINE;

EID: 84900417518     PISSN: 11778881     EISSN: None     Source Type: Journal    
DOI: 10.2147/DDDT.S59594     Document Type: Article
Times cited : (15)

References (49)
  • 1
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - an inflammatory disease
    • Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med. 1999; 340(2):115-126.
    • (1999) N Engl J Med , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 2
    • 67650720510 scopus 로고    scopus 로고
    • Immune and infammatory mechanisms of atherosclerosis (*)
    • Galkina E, Ley K. Immune and infammatory mechanisms of atherosclerosis (*). Annu Rev Immunol. 2009;27:165-197.
    • (2009) Annu Rev Immunol , vol.27 , pp. 165-197
    • Galkina, E.1    Ley, K.2
  • 3
    • 0034019601 scopus 로고    scopus 로고
    • Lessons from sudden coronary death: A comprehensive morphological classifcation scheme for atherosclerotic lesions
    • Virmani R, Kolodgie FD, Burke A P, Farb A, Schwartz SM. Lessons from sudden coronary death: a comprehensive morphological classifcation scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 2000;20(5):1262-1275.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , Issue.5 , pp. 1262-1275
    • Virmani, R.1    Kolodgie, F.D.2    Burke, A.P.3    Farb, A.4    Schwartz, S.M.5
  • 4
    • 33846677469 scopus 로고    scopus 로고
    • Functional profle of activated dendritic cells in unstable atherosclerotic plaque
    • Erbel C, Sato K, Meyer FB, et al. Functional profle of activated dendritic cells in unstable atherosclerotic plaque. Basic Res Cardiol. 2007;102(2):123-132.
    • (2007) Basic Res Cardiol , vol.102 , Issue.2 , pp. 123-132
    • Erbel, C.1    Sato, K.2    Meyer, F.B.3
  • 5
    • 2542498855 scopus 로고    scopus 로고
    • Autoimmune and infammatory mechanisms in atherosclerosis
    • Wick G, Knofach M, Xu Q. Autoimmune and infammatory mechanisms in atherosclerosis. Annu Rev Immunol. 2004;22:361-403.
    • (2004) Annu Rev Immunol , vol.22 , pp. 361-403
    • Wick, G.1    Knofach, M.2    Xu, Q.3
  • 7
    • 0027767762 scopus 로고
    • Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation
    • Freeman GJ, Gribben JG, Boussiotis VA, et al. Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science. 1993;262(5135):909-911.
    • (1993) Science , vol.262 , Issue.5135 , pp. 909-911
    • Freeman, G.J.1    Gribben, J.G.2    Boussiotis, V.A.3
  • 8
    • 0028337459 scopus 로고
    • Comparative analysis of B7-1 and B7-2 costimulatory ligands: Expression and function
    • Hathcock KS, Laszlo G, Pucillo C, Linsley P, Hodes RJ. Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J Exp Med. 1994;180(2):631-640.
    • (1994) J Exp Med , vol.180 , Issue.2 , pp. 631-640
    • Hathcock, K.S.1    Laszlo, G.2    Pucillo, C.3    Linsley, P.4    Hodes, R.J.5
  • 9
    • 0032532282 scopus 로고    scopus 로고
    • Positive and negative regulation of human T cell activation mediated by the CTLA-4/CD28 ligand CD80
    • Boulougouris G, McLeod JD, Patel YI, Ellwood CN, Walker LS, Sansom DM. Positive and negative regulation of human T cell activation mediated by the CTLA-4/CD28 ligand CD80. J Immunol. 1998;161(8):3919-3924.
    • (1998) J Immunol , vol.161 , Issue.8 , pp. 3919-3924
    • Boulougouris, G.1    McLeod, J.D.2    Patel, Y.I.3    Ellwood, C.N.4    Walker, L.S.5    Sansom, D.M.6
  • 10
    • 0029949633 scopus 로고    scopus 로고
    • The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation
    • Inobe M, Aoki N, Linsley PS, et al. The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation. J Immunol. 1996;157(2):582-588.
    • (1996) J Immunol , vol.157 , Issue.2 , pp. 582-588
    • Inobe, M.1    Aoki, N.2    Linsley, P.S.3
  • 11
    • 0034665079 scopus 로고    scopus 로고
    • CD152 ligation by CD80 on T cells is required for the induction of unresponsive-ness by costimulation-deficient antigen presentation
    • Chai JG, Vendetti S, Amofah E, Dyson J, Lechler R. CD152 ligation by CD80 on T cells is required for the induction of unresponsive-ness by costimulation-deficient antigen presentation. J Immunol. 2000;165(6):3037-3042.
    • (2000) J Immunol , vol.165 , Issue.6 , pp. 3037-3042
    • Chai, J.G.1    Vendetti, S.2    Amofah, E.3    Dyson, J.4    Lechler, R.5
  • 12
    • 0028819315 scopus 로고
    • CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL
    • Lanier LL, O'Fallon S, Somoza C, et al. CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J Immunol. 1995;154(1):97-105.
    • (1995) J Immunol , vol.154 , Issue.1 , pp. 97-105
    • Lanier, L.L.1    O'Fallon, S.2    Somoza, C.3
  • 13
    • 58149345643 scopus 로고    scopus 로고
    • T-cell costimulation and coinhibi-tion in atherosclerosis
    • Gotsman I, Sharpe AH, Lichtman AH. T-cell costimulation and coinhibi-tion in atherosclerosis. Circ Res. 2008;103(11):1220-1231.
    • (2008) Circ Res , vol.103 , Issue.11 , pp. 1220-1231
    • Gotsman, I.1    Sharpe, A.H.2    Lichtman, A.H.3
  • 14
    • 2142817119 scopus 로고    scopus 로고
    • B7-1/ B7-2 costimulation regulates plaque antigen-specifc T-cell responses and atherogenesis in low-density lipoprotein receptor-defcient mice
    • Buono C, Pang H, Uchida Y, Libby P, Sharpe AH, Lichtman AH. B7-1/ B7-2 costimulation regulates plaque antigen-specifc T-cell responses and atherogenesis in low-density lipoprotein receptor-defcient mice. Circulation. 2004;109(16):2009-2015.
    • (2004) Circulation , vol.109 , Issue.16 , pp. 2009-2015
    • Buono, C.1    Pang, H.2    Uchida, Y.3    Libby, P.4    Sharpe, A.H.5    Lichtman, A.H.6
  • 15
    • 32244445416 scopus 로고    scopus 로고
    • Natural regulatory T cells control the development of atherosclerosis in mice
    • Ait-Oufella H, Salomon BL, Potteaux S, et al. Natural regulatory T cells control the development of atherosclerosis in mice. Nat Med. 2006;12(2):178-180.
    • (2006) Nat Med , vol.12 , Issue.2 , pp. 178-180
    • Ait-Oufella, H.1    Salomon, B.L.2    Potteaux, S.3
  • 16
    • 0030848708 scopus 로고    scopus 로고
    • Costimulatory molecules in human atherosclerotic plaques: An indication of antigen specifc T lymphocyte activation
    • de Boer OJ, Hirsch F, van der Wal AC, van der Loos CM, Das PK, Becker AE. Costimulatory molecules in human atherosclerotic plaques: an indication of antigen specifc T lymphocyte activation. Atherosclerosis. 1997;133(2):227-234.
    • (1997) Atherosclerosis , vol.133 , Issue.2 , pp. 227-234
    • de Boer, O.J.1    Hirsch, F.2    van der Wal, A.C.3    van der Loos, C.M.4    Das, P.K.5    Becker, A.E.6
  • 17
    • 69949148701 scopus 로고    scopus 로고
    • Blocking T cell co-stimulation using a CD80 blocking small molecule reduces delayed type hypersensitivity responses in rhesus monkeys
    • Haanstra KG, Endell J, Estévâo D, Kondova I, Jonker M. Blocking T cell co-stimulation using a CD80 blocking small molecule reduces delayed type hypersensitivity responses in rhesus monkeys. Clin Exp Immunol. 2009;158(1):91-98.
    • (2009) Clin Exp Immunol , vol.158 , Issue.1 , pp. 91-98
    • Haanstra, K.G.1    Endell, J.2    Estévâo, D.3    Kondova, I.4    Jonker, M.5
  • 18
    • 0034020018 scopus 로고    scopus 로고
    • Natural history and histological classification of atherosclerotic lesions: An update
    • Stary HC. Natural history and histological classification of atherosclerotic lesions: an update. Arterioscler Thromb Vasc Biol. 2000;20(5):1177-1178.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , Issue.5 , pp. 1177-1178
    • Stary, H.C.1
  • 19
    • 74049100569 scopus 로고    scopus 로고
    • CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages
    • Gleissner CA, Shaked I, Erbel C, Böckler D, Katus HA, Ley K. CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages. Circ Res. 2010;106(1):203-211.
    • (2010) Circ Res , vol.106 , Issue.1 , pp. 203-211
    • Gleissner, C.A.1    Shaked, I.2    Erbel, C.3    Böckler, D.4    Katus, H.A.5    Ley, K.6
  • 20
    • 76249103398 scopus 로고    scopus 로고
    • Inhibition of IL-17A attenuates atherosclerotic lesion development in apoE-deficient mice
    • Erbel C, Chen L, Bea F, et al. Inhibition of IL-17A attenuates atherosclerotic lesion development in apoE-deficient mice. J Immunol. 2009;183(12):8167-8175.
    • (2009) J Immunol , vol.183 , Issue.12 , pp. 8167-8175
    • Erbel, C.1    Chen, L.2    Bea, F.3
  • 21
    • 33745946145 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis: Novel insights into plaque formation and destabilization
    • Stoll G, Bendszus M. Inflammation and atherosclerosis: novel insights into plaque formation and destabilization. Stroke. 2006;37(7): 1923-1932.
    • (2006) Stroke , vol.37 , Issue.7 , pp. 1923-1932
    • Stoll, G.1    Bendszus, M.2
  • 22
    • 35648992465 scopus 로고    scopus 로고
    • Synergistic proinfammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque
    • Niessner A, Shin MS, Pryshchep O, Goronzy JJ, Chaikof EL, Weyand CM. Synergistic proinfammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque. Circulation. 2007;116(18):2043-2052.
    • (2007) Circulation , vol.116 , Issue.18 , pp. 2043-2052
    • Niessner, A.1    Shin, M.S.2    Pryshchep, O.3    Goronzy, J.J.4    Chaikof, E.L.5    Weyand, C.M.6
  • 23
    • 43049179999 scopus 로고    scopus 로고
    • LPS/TLR4 signal transduction pathway
    • Lu YC, Ye h WC, Ohashi PS. LPS/TLR4 signal transduction pathway. Cytokine. 2008;42(2):145-151.
    • (2008) Cytokine , vol.42 , Issue.2 , pp. 145-151
    • Lu, Y.C.1    Yeh, W.C.2    Ohashi, P.S.3
  • 24
    • 0037066041 scopus 로고    scopus 로고
    • Expression of tolllike receptors in human atherosclerotic lesions: A possible pathway for plaque activation
    • Edfeldt K, Swedenborg J, Hansson GK, Ya n ZQ. Expression of tolllike receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation. 2002;105(10):1158-1161.
    • (2002) Circulation , vol.105 , Issue.10 , pp. 1158-1161
    • Edfeldt, K.1    Swedenborg, J.2    Hansson, G.K.3    Yan, Z.Q.4
  • 25
    • 84855857706 scopus 로고    scopus 로고
    • The tolls and dangers of atherosclerotic disease
    • Monaco C. The tolls and dangers of atherosclerotic disease. Curr Pharm Biotechnol. 2012;13(1):77-87.
    • (2012) Curr Pharm Biotechnol , vol.13 , Issue.1 , pp. 77-87
    • Monaco, C.1
  • 26
    • 27144517972 scopus 로고    scopus 로고
    • Regulation of B7.1 costimulatory molecule is mediated by the IFN regulatory factor-7 through the activation of JNK in lipopolysaccharide-stimulated human monocytic cells
    • Lim W, Gee K, Mishra S, Kumar A. Regulation of B7.1 costimulatory molecule is mediated by the IFN regulatory factor-7 through the activation of JNK in lipopolysaccharide-stimulated human monocytic cells. J Immunol. 2005;175(9):5690-5700.
    • (2005) J Immunol , vol.175 , Issue.9 , pp. 5690-5700
    • Lim, W.1    Gee, K.2    Mishra, S.3    Kumar, A.4
  • 27
    • 0033199683 scopus 로고    scopus 로고
    • Enhanced B7-2 gene expression by interferon-gamma in human mono-cytic cells is controlled through transcriptional and posttranscriptional mechanisms
    • Curiel RE, Garcia CS, Rottschafer S, Bosco MC, Espinoza-Delgado I. Enhanced B7-2 gene expression by interferon-gamma in human mono-cytic cells is controlled through transcriptional and posttranscriptional mechanisms. Blood. 1999;94(5):1782-1789.
    • (1999) Blood , vol.94 , Issue.5 , pp. 1782-1789
    • Curiel, R.E.1    Garcia, C.S.2    Rottschafer, S.3    Bosco, M.C.4    Espinoza-Delgado, I.5
  • 28
    • 0030048535 scopus 로고    scopus 로고
    • Differential modulation of B7-1 and B7-2 isoform expression on human monocytes by cytokines which infuence the development of T helper cell phenotype
    • Creery WD, Diaz-Mitoma F, Filion L, Kumar A. Differential modulation of B7-1 and B7-2 isoform expression on human monocytes by cytokines which infuence the development of T helper cell phenotype. Eur J Immunol. 1996;26(6):1273-1277.
    • (1996) Eur J Immunol , vol.26 , Issue.6 , pp. 1273-1277
    • Creery, W.D.1    Diaz-Mitoma, F.2    Filion, L.3    Kumar, A.4
  • 29
    • 0032055964 scopus 로고    scopus 로고
    • Stimulation of human T lymphocytes by LPS is MHC unrestricted, but strongly dependent on B7 interactions
    • Mattern T, Flad HD, Brade L, Rietschel ET, Ulmer AJ. Stimulation of human T lymphocytes by LPS is MHC unrestricted, but strongly dependent on B7 interactions. J Immunol. 1998;160(7):3412-3418.
    • (1998) J Immunol , vol.160 , Issue.7 , pp. 3412-3418
    • Mattern, T.1    Flad, H.D.2    Brade, L.3    Rietschel, E.T.4    Ulmer, A.J.5
  • 30
    • 71649108018 scopus 로고    scopus 로고
    • Adaptive immunity and atherosclerosis
    • Andersson J, Libby P, Hansson GK. Adaptive immunity and atherosclerosis. Clin Immunol. 2010;134(1):33-46.
    • (2010) Clin Immunol , vol.134 , Issue.1 , pp. 33-46
    • Andersson, J.1    Libby, P.2    Hansson, G.K.3
  • 31
    • 0041776261 scopus 로고    scopus 로고
    • Adhesion molecules and atherosclerosis
    • Blankenberg S, Barbaux S, Tiret L. Adhesion molecules and atherosclerosis. Atherosclerosis. 2003;170(2):191-203.
    • (2003) Atherosclerosis , vol.170 , Issue.2 , pp. 191-203
    • Blankenberg, S.1    Barbaux, S.2    Tiret, L.3
  • 32
    • 33645324773 scopus 로고    scopus 로고
    • Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque
    • Zhang X, Niessner A, Nakajima T, et al. Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque. Circ Res. 2006;98(4): 524-531.
    • (2006) Circ Res , vol.98 , Issue.4 , pp. 524-531
    • Zhang, X.1    Niessner, A.2    Nakajima, T.3
  • 33
    • 20444381299 scopus 로고    scopus 로고
    • Interferon-gamma and atherosclerosis: Pro- or anti-atherogenic?
    • Harvey EJ, Ramji D P. Interferon-gamma and atherosclerosis: pro- or anti-atherogenic? Cardiovasc Res. 2005;67(1):11-20.
    • (2005) Cardiovasc Res , vol.67 , Issue.1 , pp. 11-20
    • Harvey, E.J.1    Ramji, D.P.2
  • 34
    • 34547618784 scopus 로고    scopus 로고
    • A novel class of antioxidants inhibit LPS induction of tissue factor by selective inhibition of the activation of ASK1 and MAP kinases
    • Luyendyk J P, Piper JD, Tencati M, et al. A novel class of antioxidants inhibit LPS induction of tissue factor by selective inhibition of the activation of ASK1 and MAP kinases. Arterioscler Thromb Vasc Biol. 2007;27(8):1857-1863.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.8 , pp. 1857-1863
    • Luyendyk, J.P.1    Piper, J.D.2    Tencati, M.3
  • 35
    • 0030596136 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-8 protein and gene expression in human arterial atherosclerotic wall
    • Rus HG, Vlaicu R, Niculescu F. Interleukin-6 and interleukin-8 protein and gene expression in human arterial atherosclerotic wall. Atherosclerosis. 1996;127(2):263-271.
    • (1996) Atherosclerosis , vol.127 , Issue.2 , pp. 263-271
    • Rus, H.G.1    Vlaicu, R.2    Niculescu, F.3
  • 36
    • 34249678457 scopus 로고    scopus 로고
    • T(H)1 cells control themselves by producing interleukin-10
    • O'Garra A, Vieira P. T(H)1 cells control themselves by producing interleukin-10. Nat Rev Immunol. 2007;7(6):425-428.
    • (2007) Nat Rev Immunol , vol.7 , Issue.6 , pp. 425-428
    • O'Garra, A.1    Vieira, P.2
  • 37
    • 55149094739 scopus 로고    scopus 로고
    • Interleukin-10: New perspectives on an old cytokine
    • Mosser DM, Zhang X. Interleukin-10: new perspectives on an old cytokine. Immunol Rev. 2008;226:205-218.
    • (2008) Immunol Rev , vol.226 , pp. 205-218
    • Mosser, D.M.1    Zhang, X.2
  • 38
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-defcient mice
    • Gu L, Okada Y, Clinton SK, et al. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-defcient mice. Mol Cell. 1998;2(2):275-281.
    • (1998) Mol Cell , vol.2 , Issue.2 , pp. 275-281
    • Gu, L.1    Okada, Y.2    Clinton, S.K.3
  • 39
    • 0030698683 scopus 로고    scopus 로고
    • Expression of inflammatory mediators and adhesion molecules in human atherosclerotic plaque
    • DeGraba TJ. Expression of inflammatory mediators and adhesion molecules in human atherosclerotic plaque. Neurology. 1997; 49(5 Suppl 4):S15-S19.
    • (1997) Neurology , vol.49 , Issue.5 SUPPL. 4
    • Degraba, T.J.1
  • 40
    • 48249103057 scopus 로고    scopus 로고
    • Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
    • Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S. Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc Natl Acad Sci U S A. 2008;105(29):10113-10118.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.29 , pp. 10113-10118
    • Onishi, Y.1    Fehervari, Z.2    Yamaguchi, T.3    Sakaguchi, S.4
  • 41
    • 44449096726 scopus 로고    scopus 로고
    • IL-10: The master regulator of immunity to infection
    • Couper KN, Blount DG, Riley EM. IL-10: the master regulator of immunity to infection. J Immunol. 2008;180(9):5771-5777.
    • (2008) J Immunol , vol.180 , Issue.9 , pp. 5771-5777
    • Couper, K.N.1    Blount, D.G.2    Riley, E.M.3
  • 42
    • 33748756806 scopus 로고    scopus 로고
    • NF-kappaB1 (p50) homodi-mers differentially regulate pro- and anti-infammatory cytokines in macrophages
    • Cao S, Zhang X, Edwards J P, Mosser DM. NF-kappaB1 (p50) homodi-mers differentially regulate pro- and anti-infammatory cytokines in macrophages. J Biol Chem. 2006;281(36):26041-26050.
    • (2006) J Biol Chem , vol.281 , Issue.36 , pp. 26041-26050
    • Cao, S.1    Zhang, X.2    Edwards, J.P.3    Mosser, D.M.4
  • 43
    • 33745815324 scopus 로고    scopus 로고
    • Dynamic and transient remodeling of the macrophage IL-10 promoter during transcription
    • Zhang X, Edwards J P, Mosser DM. Dynamic and transient remodeling of the macrophage IL-10 promoter during transcription. J Immunol. 2006;177(2):1282-1288.
    • (2006) J Immunol , vol.177 , Issue.2 , pp. 1282-1288
    • Zhang, X.1    Edwards, J.P.2    Mosser, D.M.3
  • 44
    • 70349736116 scopus 로고    scopus 로고
    • Cross-regulation of signaling pathways by interferon-gamma: Implications for immune responses and autoimmune diseases
    • Hu X, Ivashkiv LB. Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases. Immunity. 2009;31(4):539-550.
    • (2009) Immunity , vol.31 , Issue.4 , pp. 539-550
    • Hu, X.1    Ivashkiv, L.B.2
  • 45
    • 0036606913 scopus 로고    scopus 로고
    • Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster
    • Triantaflou M, Triantaflou K. Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Trends Immunol. 2002;23(6): 301-304.
    • (2002) Trends Immunol , vol.23 , Issue.6 , pp. 301-304
    • Triantaflou, M.1    Triantaflou, K.2
  • 46
    • 0036067659 scopus 로고    scopus 로고
    • Toll receptors, CD14, and macrophage activation and deactivation by LPS
    • Dobrovolskaia MA, Vogel SN. Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect. 2002;4(9): 903-914.
    • (2002) Microbes Infect , vol.4 , Issue.9 , pp. 903-914
    • Dobrovolskaia, M.A.1    Vogel, S.N.2
  • 47
    • 77956289866 scopus 로고    scopus 로고
    • Palmitate induced IL-6 and MCP-1 expression in human bladder smooth muscle cells provides a link between diabetes and urinary tract infections
    • Oberbach A, Schlichting N, Blüher M, et al. Palmitate induced IL-6 and MCP-1 expression in human bladder smooth muscle cells provides a link between diabetes and urinary tract infections. PLoS One. 2010;5(5):e10882.
    • (2010) PLoS One , vol.5 , Issue.5
    • Oberbach, A.1    Schlichting, N.2    Blüher, M.3
  • 48
    • 58949094248 scopus 로고    scopus 로고
    • Flagellin and lipopoly-saccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-kappaB signaling pathways
    • Kogut MH, Genovese KJ, He H, Kaiser P. Flagellin and lipopoly-saccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-kappaB signaling pathways. Innate Immun. 2008;14(4): 213-222.
    • (2008) Innate Immun , vol.14 , Issue.4 , pp. 213-222
    • Kogut, M.H.1    Genovese, K.J.2    He, H.3    Kaiser, P.4
  • 49
    • 0036467440 scopus 로고    scopus 로고
    • Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1
    • Nakahira M, Ahn HJ, Park WR, et al. Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1. J Immunol. 2002;168(3):1146-1153.
    • (2002) J Immunol , vol.168 , Issue.3 , pp. 1146-1153
    • Nakahira, M.1    Ahn, H.J.2    Park, W.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.