Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13602-13614

  Chai, Ryan C ^a   Kouspou, Michelle M ^a   Lang, Benjamin J ^a   Nguyen, Chau H ^a   Van Der Kraan, A Gabrielle J ^a,b   Vieusseux, Jessica L ^a   Lim, Reece C ^a   Gillespie, Matthew T ^a,b   Benjamin, Ivor J ^c   Quinn, Julian M W ^a,b   Price, John T ^a,d  

^a MONASH UNIVERSITY   (Australia)

^b HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d VICTORIA UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALS; TRANSCRIPTION FACTORS;

17--17-DEMETHOXYGELDANAMYCIN; HEAT SHOCK RESPONSE; HEAT-SHOCK FACTOR 1; MOUSE BONE MARROW CELLS; OSTEOCLAST DIFFERENTIATION; OSTEOCLAST FORMATION; PHARMACOLOGICAL INHIBITION; TRANSCRIPTIONAL REGULATOR;

BONE;

ALCOHOL; ALVESPIMYCIN; COUMAMYCIN A1; DOXORUBICIN; HEAT SHOCK PROTEIN 90 INHIBITOR; HEAT SHOCK TRANSCRIPTION FACTOR 1; METHOTREXATE; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; NOVOBIOCIN; RADICICOL; SHORT HAIRPIN RNA; TANESPIMYCIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRESS; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEAT SHOCK RESPONSE; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BONE; CELL STRESS; CHEMOTHERAPY; HEAT SHOCK PROTEIN; HSF1; HSP90; HSP90 INHIBITORS; OSTEOCLAST; STRESS RESPONSE;

ANIMALS; BENZOQUINONES; BONE RESORPTION; CELL DIFFERENTIATION; CELL LINE; DNA-BINDING PROTEINS; HSP90 HEAT-SHOCK PROTEINS; LACTAMS, MACROCYCLIC; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; OSTEOCLASTS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS;

EID: 84900416874     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.530626     Document Type: Article

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