Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretion

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13575-13588

  El Azzouny, Mahmoud ^a,b   Evans, Charles R ^a   Treutelaar, Mary K ^a   Kennedy, Robert T ^a,b   Burant, Charles F ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; GLUCOSE; GLYCEROL; INSULIN; METABOLISM; PHOSPHOLIPIDS; PHYSIOLOGY;

DIHYDROXYACETONE PHOSPHATE; GLUCOSE METABOLISM; GLUCOSE-STIMULATED INSULIN SECRETIONS; LYSOPHOSPHATIDIC ACID; METABOLIC PATHWAYS; METABOLITE PROFILING; OXYGEN CONSUMPTION; RECEPTOR SIGNALING;

FATTY ACIDS;

DIACYLGLYCEROL; DIHYDROXYACETONE PHOSPHATE; FATTY ACID; G PROTEIN COUPLED RECEPTOR 40; GLUCOSE; GLYCEROLIPID; GLYCEROPHOSPHATE; LONG CHAIN ACYL COENZYME A DEHYDROGENASE; LYSOPHOSPHATIDIC ACID; MONOACYLGLYCEROL; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TRICARBOXYLIC ACID;

ARTICLE; CELL METABOLISM; ESTERIFICATION; FATTY ACID TRANSPORT; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; GLYCOLYSIS; INS 1 CELL LINE; INSULIN RELEASE; LIPID METABOLISM; LIPOGENESIS; METABOLOME; OXYGEN CONSUMPTION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

DIABETES; FATTY ACID METABOLISM; FATTY ACID POTENTIATION OF GSIS; G PROTEIN-COUPLED RECEPTORS (GPCR); GLUCOSE METABOLISM; GPR40; INSULIN SECRETION; METABOLISM; METABOLOMICS; Β CELL;

ANIMALS; CELL LINE; FATTY ACIDS; GLUCOSE; GLYCEROPHOSPHOLIPIDS; INSULIN; INSULIN-SECRETING CELLS; LIPID METABOLISM; METABOLOME; OXIDATION-REDUCTION; RATS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84900413588     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.531970     Document Type: Article

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