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Volumn 9, Issue 5, 2014, Pages

Enhanced production of docosahexaenoic acid in mammalian cells

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; DOCOSAHEXAENOIC ACID; DOCOSAPENTAENOIC ACID; FISH PROTEIN; LINOLENIC ACID; UNSATURATED FATTY ACID;

EID: 84900393838     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096503     Document Type: Article
Times cited : (7)

References (34)
  • 1
    • 0346095554 scopus 로고    scopus 로고
    • Is Docosahexaenoic Acid (DHA) Essential? Lessons from DHA Status Regulation, Our Ancient Diet, Epidemiology and Randomized Controlled Trials
    • Muskiet FA, Fokkema MR, Schaafsma A, Boersma ER, Crawford MA (2004) Is docosahexaenoic acid (DHA) essential? Lessons from DHA status regulation, our ancient diet, epidemiology and randomized controlled trials. J. Nutr. 134: 183-186. (Pubitemid 38057445)
    • (2004) Journal of Nutrition , vol.134 , Issue.1 , pp. 183-186
    • Muskiet, F.A.J.1    Fokkema, M.R.2    Schaafsma, A.3    Boersma, E.R.4    Crawford, M.A.5
  • 3
    • 0037633085 scopus 로고    scopus 로고
    • The structure of DHA in phospholipid membranes
    • DOI 10.1007/s11745-003-1082-0
    • Gawrisch K, Eldho NV, Holte LL (2003) The structure of DHA in phospholipid membranes. Lipids. 38: 445-452. (Pubitemid 36724304)
    • (2003) Lipids , vol.38 , Issue.4 , pp. 445-452
    • Gawrisch, K.1    Eldho, N.V.2    Holte, L.L.3
  • 4
    • 0242383270 scopus 로고    scopus 로고
    • DHA-rich phospholipids optimize G-protein-coupled signaling
    • Mitchell DC, Niu SL, Litman BJ (2003) DHA-rich phospholipids optimize G-protein-coupled signaling. J. Pediatr. 143 (Suppl.): 80-86.
    • (2003) J. Pediatr. , vol.143 , Issue.SUPPL. , pp. 80-86
    • Mitchell, D.C.1    Niu, S.L.2    Litman, B.J.3
  • 5
    • 0037633103 scopus 로고    scopus 로고
    • Enhancement of G protein-coupled signaling by DHA phospholipids
    • DOI 10.1007/s11745-003-1081-1
    • Mitchell DC, Niu SL, Litman BJ (2003) Enhancement of G protein-coupled signaling by DHA phospholipids. Lipids. 38:437-443. (Pubitemid 36724303)
    • (2003) Lipids , vol.38 , Issue.4 , pp. 437-443
    • Mitchell, D.C.1    Niu, S.-L.2    Litman, B.J.3
  • 6
    • 3843115666 scopus 로고    scopus 로고
    • Reduced G protein-coupled signaling efficiency in retinal rod outer segments in response to n-3 fatty acid deficiency
    • DOI 10.1074/jbc.M404376200
    • Niu SL, Mitchell DC, Lim SY, Wen ZM, Kim HY, et al. (2004) Reduced G protein-coupled signaling efficiency in retinal rod outer segments in response to n-3 fatty acid deficiency. J. Biol. Chem. 279: 31098-31104. (Pubitemid 39037771)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.30 , pp. 31098-31104
    • Niu, S.-L.1    Mitchell, D.C.2    Lim, S.-Y.3    Wen, Z.-M.4    Kim, H.-Y.5    Salem Jr., N.6    Litman, B.J.7
  • 7
    • 0035066651 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid regulation of gene transcription: A molecular mechanism to improve the metabolic syndrome
    • Clarke SD (2001) Polyunsaturated fatty acid regulation of gene transcription: a molecular mechanism to improve the metabolic syndrome. J. Nutr. 131: 1129-1132.
    • (2001) J. Nutr. , vol.131 , pp. 1129-1132
    • Clarke, S.D.1
  • 8
    • 0033777508 scopus 로고    scopus 로고
    • Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration
    • Moriguchi T, Greiner RS, Salem NJr (2000) Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration. J. Neurochem. 75: 2563-2573.
    • (2000) J. Neurochem. , vol.75 , pp. 2563-2573
    • Moriguchi, T.1    Greiner, R.S.2    Salem Jr., N.3
  • 9
    • 0036122486 scopus 로고    scopus 로고
    • Docosahexaenoic acid-rich phospholipid supplementation: Effect on behavior, learning ability, and retinal function in control and n-3 polyunsaturated fatty acid deficient old mice
    • DOI 10.1080/10284150290007074
    • Carrie I, Smirnova M, Clement M, De Javel D, Frances H et al. (2002) Docosahexaenoic acid-rich phospholipid supplementation: effect on behavior, learning ability, and retinal function in control and n-3 polyunsaturated fatty acid deficient old mice. Nutr. Neurosci. 5: 43-52. (Pubitemid 34228993)
    • (2002) Nutritional Neuroscience , vol.5 , Issue.1 , pp. 43-52
    • Carrie, I.1    Smirnova, M.2    Clement, M.3    De Javel, D.4    Frances, H.5    Bourre, J.M.6
  • 11
    • 33749037423 scopus 로고    scopus 로고
    • Omega-3 fatty acids and rodent behavior
    • DOI 10.1016/j.plefa.2006.07.006, PII S0952327806001207, The Emerging Role of Omega-3 Fatty Acids in Psychiatry
    • Fedorova I, Salem NJr (2006) Omega-3 fatty acids and rodent behavior. Prostaglandins Leukot. Essent. Fatty Acids. 75: 271-289. (Pubitemid 44444990)
    • (2006) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.75 , Issue.4-5 , pp. 271-289
    • Fedorova, I.1    Salem Jr., N.2
  • 12
    • 0032996011 scopus 로고    scopus 로고
    • Rats with low levels of brain docosahexaenoic acid show impaired performance in olfactory-based and spatial learning tasks
    • Greiner RS, Moriguchi T, Hutton A, Slotnick BM, Salem NJr (1999) Rats with low levels of brain docosahexaenoic acid show impaired performance in olfactory-based and spatial learning tasks. Lipids. 34 (Suppl): 239-243.
    • (1999) Lipids. , vol.34 , Issue.SUPPL. , pp. 239-243
    • Greiner, R.S.1    Moriguchi, T.2    Hutton, A.3    Slotnick, B.M.4    Salem Jr., N.5
  • 14
    • 0033662578 scopus 로고    scopus 로고
    • The role of dietary n-6 and n-3 fatty acids in the developing brain
    • Innis SM (2000) The role of dietary n-6 and n-3 fatty acids in the developing brain. Dev. Neurosci. 22: 474-480.
    • (2000) Dev. Neurosci. , vol.22 , pp. 474-480
    • Innis, S.M.1
  • 15
    • 0033954768 scopus 로고    scopus 로고
    • Infant vision and retinal function in studies of dietary long-chain polyunsaturated fatty acids: Methods, results, and implications
    • Neuringer M (2000) Infant vision and retinal function in studies of dietary long-chain polyunsaturated fatty acids: methods, results, and implications. Am. J. Clin. Nutr. 71 (Suppl.): 256-267.
    • (2000) Am. J. Clin. Nutr. , vol.71 , Issue.SUPPL. , pp. 256-267
    • Neuringer, M.1
  • 17
    • 34147161672 scopus 로고    scopus 로고
    • Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula
    • DOI 10.1016/j.earlhumdev.2006.11.003, PII S0378378206003033
    • Birch EE, Garfield S, Castaneda Y, Hughbanks-Wheaton D, Uauy R, et al. (2007) Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula. Early Hum.Dev. 83: 279-284. (Pubitemid 46561172)
    • (2007) Early Human Development , vol.83 , Issue.5 , pp. 279-284
    • Birch, E.E.1    Garfield, S.2    Castaneda, Y.3    Hughbanks-Wheaton, D.4    Uauy, R.5    Hoffman, D.6
  • 18
    • 0035160423 scopus 로고    scopus 로고
    • Randomized trials with polyunsaturated fatty acid interventions in preterm and term infants: Functional and clinical outcomes
    • Gibson RA, Chen W, Makrides M (2001) Randomized trials with polyunsaturated fatty acid interventions in preterm and term infants: functional and clinical outcomes. Lipids. 36: 873-883. (Pubitemid 33065188)
    • (2001) Lipids , vol.36 , Issue.9 , pp. 873-883
    • Gibson, R.A.1    Chen, W.2    Makrides, M.3
  • 19
    • 0037844785 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression
    • DOI 10.1176/appi.ajp.160.5.996
    • Marangell LB, Martinez JM, Zboyan HA, Kertz B, Kim HF, et al. (2003) A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am. J. Psychiatry. 160: 996-998. (Pubitemid 41079588)
    • (2003) American Journal of Psychiatry , vol.160 , Issue.5 , pp. 996-998
    • Marangell, L.B.1    Martinez, J.M.2    Zboyan, H.A.3    Kertz, B.4    Kim, H.F.S.5    Puryear, L.J.6
  • 20
    • 0344873737 scopus 로고    scopus 로고
    • Increased risk of postpartum depressive symptoms is associated with slower normalization after pregnancy of the functional docosahexaenoic acid status
    • DOI 10.1016/S0952-3278(03)00090-5
    • Otto SJ, Groot RH, Hornstra G (2003) Increased risk of postpartum depressive symptoms is associated with slower normalization after pregnancy of the functional docosahexaenoic acid status. Prostaglandins Leukot. Essent. Fatty Acids. 69: 237-243. (Pubitemid 37463804)
    • (2003) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.69 , Issue.4 , pp. 237-243
    • Otto, S.J.1    De Groot, R.H.M.2    Hornstra, G.3
  • 21
    • 18844472139 scopus 로고    scopus 로고
    • Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late- onset alcoholics
    • DOI 10.1016/S0006-3223(98)00141-3, PII S0006322398001413
    • Hibbeln JR, Linnoila M, Umhau JC, Rawlings R, George DT, et al. (1998) Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics. Biol. Psychiatry. 44:235-242. (Pubitemid 28389708)
    • (1998) Biological Psychiatry , vol.44 , Issue.4 , pp. 235-242
    • Hibbeln, J.R.1    Linnoila, M.2    Umhau, J.C.3    Rawlings, R.4    George, D.T.5    Salem Jr., N.6
  • 22
    • 3142753961 scopus 로고    scopus 로고
    • Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases
    • Nakamura MT, Nara TY (2004) Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases. Annu. Rev. Nutr. 24, 345-376
    • (2004) Annu. Rev. Nutr. , vol.24 , pp. 345-376
    • Nakamura, M.T.1    Nara, T.Y.2
  • 24
    • 0030058372 scopus 로고    scopus 로고
    • Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants
    • Salem NJr, Wegher JB, Mena P, Uauy R(1996) Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants. Proc. Natl. Acad. Sci. USA. 93: 49-54.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 49-54
    • Salem Jr., N.1    Wegher, J.B.2    Mena, P.3    Uauy, R.4
  • 25
    • 23844432885 scopus 로고    scopus 로고
    • Alpha-linolenic acid does not contribute appreciably to docosahexaenoic acid within brain phospholipids of adult rats fed a diet enriched in docosahexaenoic acid
    • DOI 10.1111/j.1471-4159.2005.03258.x
    • DeMar JC, Ma JK, Chang L, Bell JM, Rapoport SI (2005) Alpha-linolenic acid does not contribute appreciably to docosahexaenoic acid within brain phospholipids of adult rats fed a diet enriched in docosahexaenoic acid. J. Neurochem. 94: 1063-1076. (Pubitemid 41170593)
    • (2005) Journal of Neurochemistry , vol.94 , Issue.4 , pp. 1063-1076
    • DeMar Jr., J.C.1    Ma, K.2    Chang, L.3    Bell, J.M.4    Rapoport, S.I.5
  • 26
    • 34248204099 scopus 로고    scopus 로고
    • Docosahexaenoic acid synthesis from alpha-linolenic acid by rat brain is unaffected by dietary n-3 PUFA deprivation
    • DOI 10.1194/jlr.M600549-JLR200
    • Igarashi M, DeMar JC, Ma JK, Chang L, Bell JM, Rapoport SI.(2007) Docosahexaenoic acid synthesis from alpha-linolenic acid by rat brain is unaffected by dietary n-3 PUFA deprivation. J. Lipid Res. 48: 1150-1158. (Pubitemid 46708682)
    • (2007) Journal of Lipid Research , vol.48 , Issue.5 , pp. 1150-1158
    • Igarashi, M.1    DeMar Jr., J.C.2    Ma, K.3    Chang, L.4    Bell, J.M.5    Rapoport, S.I.6
  • 27
    • 0020010537 scopus 로고
    • Dietary requirements and functions of alpha-linolenic acid in animals
    • Tinoco J (1982) Dietary requirements and functions of alpha-linolenic acid in animals. Prog. Lipid Res. 21, 1-45.
    • (1982) Prog. Lipid Res. , vol.21 , pp. 1-45
    • Tinoco, J.1
  • 28
    • 0022446986 scopus 로고
    • Control of polyunsaturated acids in tissue lipids
    • Holman RT (1986) Control of polyunsaturated acids in tissue lipids. J. Am. Coll. Nutr. 5, 183-211.
    • (1986) J. Am. Coll. Nutr. , vol.5 , pp. 183-211
    • Holman, R.T.1
  • 30
    • 33645034015 scopus 로고    scopus 로고
    • Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan
    • Tripodi KEJ, Buttigliero LV, Altabe SG, Uttaro AD (2006) Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan. FEBS J 273:271-280.
    • (2006) FEBS J , vol.273 , pp. 271-280
    • Tripodi, K.E.J.1    Buttigliero, L.V.2    Altabe, S.G.3    Uttaro, A.D.4
  • 31
    • 0042026506 scopus 로고    scopus 로고
    • Biosynthesis of docosahexaenoic acid in Euglena gracilis: Biochemical and molecular evidence for the involvement of a Δ4-fatty acyl group desaturase
    • DOI 10.1021/bi034731y
    • Meyer A, Cirpus P, Ott C, Schlecker R, Zähringer U, et al. (2003) Biosynthesis of docosahexaenoic acid in Euglena gracilis: Biochemical and molecular evidence for the involvement of a Δ4-fatty acyl group desaturase. Biochemistry 42:9779-9788. (Pubitemid 36993151)
    • (2003) Biochemistry , vol.42 , Issue.32 , pp. 9779-9788
    • Meyer, A.1    Cirpus, P.2    Ott, C.3    Schlecker, R.4    Zahringer, U.5    Heinz, E.6
  • 32
    • 0142231412 scopus 로고    scopus 로고
    • Identification of a very long chain polyunsaturated fatty acid Δ4-desaturase from the microalga Pavlova lutheri
    • DOI 10.1016/S0014-5793(03)01078-0
    • Tonon T, Harvey D, Larson TR, Graham IA (2003) Identification of a very long chain polyunsaturated fatty acid Δ4-desaturase from the microalga Pavlova lutheri. FEBS Lett 553:440-444. (Pubitemid 37315646)
    • (2003) FEBS Letters , vol.553 , Issue.3 , pp. 440-444
    • Tonon, T.1    Harvey, D.2    Larson, T.R.3    Graham, I.A.4
  • 33
    • 0035943661 scopus 로고    scopus 로고
    • Identification of a Δ4 fatty acid desaturase from Thraustochytrium sp involved in the biosynthesis of docosahexanoic acid by heterologous expression in Saccharomyces cerevisiae and Brassica juncea
    • Qiu X, Hong H, MacKenzie SL (2001) Identification of a Δ4 fatty acid desaturase from Thraustochytrium sp involved in the biosynthesis of docosahexanoic acid by heterologous expression in Saccharomyces cerevisiae and Brassica juncea. J Biol Chem 276:31561-31566.
    • (2001) J Biol Chem , vol.276 , pp. 31561-31566
    • Qiu, X.1    Hong, H.2    MacKenzie, S.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.