Natural potential therapeutic agents of neurodegenerative diseases from the traditional herbal medicine Chinese Dragon Blood

Journal of Ethnopharmacology

Volumn 152, Issue 3, 2014, Pages 508-521

  Li, Ning ^a   Ma, Zhongjun ^b   Li, Mujie ^a   Xing, Yachao ^a   Hou, Yue ^c  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c NORTHEASTERN UNIVERSITY   (China)

Author keywords

Anti inflammatory effect; Chinese Dragon Blood; Dracaena cochinchinensis S.C. Chen; NQO1 inducing activity; Polymers; Therapeutic agents for neurodegenerative diseases

Indexed keywords

1,2,4,5 TETRACHLORO 3,6 DIMETHOXYBENZENE; 10 HYDROXY 11 METHOXYDRACAENONE; 3,4 DIHYDROXYALLYL BENZENE; 4 HYDROXYBENZOIC ETHYL ESTER; 4' HYDROXY 2,4 DIMETHOXYDIHYDROCHALCONE; 4' HYDROXY 2,4 TRIMETHOXYDIHYDROCHALCONE; 4' HYDROXY 7 METHOXY 8 METHYLFLAVANE; 5,4' DIHYDROXY 7 METHOXY 6 METHYLFLAVANE; 6 METHOXY 7 HYDROXYFLAVONE; 6,4' DIHYDROXY 7 METHOXYHOMOISOFLAVANE; 7 HYDROXY 4' METHOXYFLAVANE; 7,4' DIHYDROXYHOMOISOFLAVANE; ANTIINFLAMMATORY AGENT; COCHINCHINENENE E; COCHINCHINENENE F; DIOSGENIN; DRACAENA COCHINCHINENSIS; DRACAENOL C; PLANT MEDICINAL PRODUCT; PTEROSTILBENE; SPIROST 5,25(27) DIENE 1BETA 3BETA DIOL; STIGMAST 5,22 DIENE 3 O BETA DEXTRO GLUCOPYRANOSIDE; UNCLASSIFIED DRUG; DRAGON'S BLOOD; NQO1 PROTEIN, RAT; PLANT EXTRACT; PLANT RESIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHINESE; CHINESE HERB; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG CYTOTOXICITY; DRUG EFFECT; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NERVE DEGENERATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; ANIMAL; CELL LINE; CHEMISTRY; CHINESE MEDICINE; DRACAENA; DRUG EFFECTS; INFLAMMATION; METABOLISM; MOUSE; NEURODEGENERATIVE DISEASES; PATHOLOGY; PATHOPHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CELL LINE, TUMOR; DRACAENA; INFLAMMATION; MEDICINE, CHINESE TRADITIONAL; MICE; NAD(P)H DEHYDROGENASE (QUINONE); NEURODEGENERATIVE DISEASES; PLANT EXTRACTS; RESINS, PLANT;

EID: 84900358732     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.01.032     Document Type: Article

References (29)

1. J.K. Andersen Oxidative stress in neurodegeneration: cause or consequence Nat. Med. 10 Suppl 2004 S18 25
2. S.C. Barber, and P.J. Shaw Oxidative stress in ALS: key role in motor neuron injury and therapeutic target Free Radical Biol. Med. 48 2010 629 641
3. S.W. Barger, and A.D. Harmon Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E Nature 388 1997 878 881
4. N. Cho, J.H. Choi, H.J. Yang, E.J. Jeong, K.Y. Lee, Y.C. Kim, and S.H. Sung Neuroprotective and anti-inflammatory effects of flavonoids isolated from Rhus verniciflua in neuronal HT22 and microglial BV2 cell lines Food Chem. Toxicol. 50 2012 1940 1945
5. G.E. Gibson, and H. Zhang Abnormalities in oxidative processes in non-neuronal tissues from patients with Alzheimer's disease J. Alzheimer's Dis. 3 2001 329 338
6. D. Gupta, B. Bleakley, and R.K. Gupta Dragon's blood: botany, chemistry and therapeutic uses J. Ethnopharmacol. 115 2008 361 380
7. B. Halliwell Oxidative stress and neurodegeneration: where are we now J. Neurochem. 97 2006 1634 1658
8. Y. Hou, C.F. Wu, J.Y. Yang, X. He, X.L. Bi, L. Yu, and T. Guo Effects of clozapine, olanzapine and haloperidol on nitric oxide production by lipopolysaccharide-activated N9 cells Prog. Neuropsychopharmacol. Biol. Psychiatry 30 2006 1523 1528
9. O. Hwang Role of oxidative stress in Parkinson' s disease Exp. Neurobiol. 22 2013 11 17
10. Y.H. Lee, S.H. Jeon, S.H. Kim, C. Kim, S.J. Lee, D. Koh, Y. Lim, K. Ha, and S.Y. Shin A new synthetic chalcone derivative, 2-hydroxy-3',5,5'- trimethoxychalcone (DK-139), suppresses the toll-like receptor 4-mediated inflammatory response through inhibition of the Akt/NF-κB pathway in BV2 microglial cells Exp. Mol. Med. 44 2012 369 377
11. M.J. Li, F. Liu, H.M. Hua, and N. Li Flavanes and homoisoflavanes in Chinese Dragon's Blood Drug Clin. 27 2012 196 199
12. J.H. Lim, K.M. Kim, S.W. Kim, O. Hwang, and H.J. Choi Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: novel cytoprotective mechanism against oxidative damage Pharmacol. Res. 57 2008 325 331
13. S.S. Kim, J.H. Lim, Y. Banga, J. Gal, S.U. Lee, Y.C. Cho, G. Yoon, B.Y. Kang, S.H. Cheon, and H.J. Choi LicochalconeE activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease J. Nutr. Biochem. 23 2013 1314 1323
14. L.P. Luo, R.H. Wang, X.J. Wang, Z.J. Ma, and N. Li Compounds from Angelica keiskei with NQO1 induction, DPPH scavenging and α-glucosidase inhibitory activities Food Chem. 131 2012 992 998
15. F.M. Menzies, P.G. Ince, and P.J. Shaw Mitochondrial involvement in amyotrophic lateral sclerosis Neurochem. Int. 40 2002 543 551
16. W.B. Pan, F.R. Chang, L.M. Wei, and Y.C. Wu New flavans, spirostanol sapogenins, and a pregnane genin from Tupistra chinensis and their cytotoxicity J. Nat. Prod. 66 2003 161 168
17. J.S. Park, J.S. Jung, Y.H. Jeong, J.W. Hyun, T.K. Van Le, D.H. Kim, E.C. Choi, and H.S. Kim Antioxidant mechanism of isoflavone metabolites in hydrogen peroxide-stimulated rat primary astrocytes: critical role of hemeoxygenase-1 and NQO1 expression J. Neurochem. 119 2011 909 919
18. V. Pathak, O. Shirota, S. Sekita, Y. Hirayama, Y. Hakamata, T. Hayashi, T. Yanagawa, and M. Satake Antiandrogenic phenolic constituents from Dalbergia cochinchinensis Phytochemistry 46 1997 1219 1223
19. S. Saleppico, R. Mazzolla, J.R. Boelaert, M. Puliti, R. Barluzzi, F. Bistoni, and E. Blasi Iron regulates microglial cell-mediated secretory and effector functions Cell. Immunol. 170 1996 251 259
20. K. Takuya, T. Kazunori, Y. Yoshiko, Y. Kaori, H. Shinji, Y. Fumihito, H. Noriaki, and I. Joh-E. A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2- yl))-2-(2,4,6-trimethyl phenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2-ARE pathway: therapeutic implications for ALS Free Radical Biol. Med. 53 2012 2028 2042
21. R.J. Tang, D.X. Wen, H. Wei, and N.J. Bi Constituents of the petroleum ether and ethyl acetate extract fractions from Dracaena cochinensis (Lour.) S.C. Chen Chin. J. Chin. Mater. Med. 20 1995 421 423
22. J.L. Wang, X.C. Li, D.F. Jiang, P. Ma, and C.R. Yang Chemical constituents of Dragon's Blood resin from Dracaena cochinchinensis in Yunnan and their antifungal activity Acta Bot. Yunnan 17 1995 336 340
23. H. Wei, D.X. Wen, X.S. Liu, and R.J. Tang Constituents in petroleum ether and ethyl acetate extract fractions of Dracaena cochinensis (Lour.)S.C. Chen Chin. J. Chin. Mater. Med. 23 1998 616 618
24. N. Xina, Y.J. Li, Y. Li, R.J. Dai, W. Meng, Y. Chen, M. Schlappi, and Y.L. Deng Dragon's Blood extract has antithrombotic properties, affecting platelet aggregation functions and anticoagulation activities J. Ethnopharmacol. 135 2011 510 514
25. T. Yi, H.B. Chen, Z.Z. Zhao, Z.L. Yu, and Z.H. Jiang Comparison of the chemical profiles and anti-platelet aggregation effects of two "Dragon's Blood" drugs used in traditional Chinese medicine J. Ethnopharmacol. 133 2011 796 802
26. Q.A. Zheng Study on Chinese Dragon's Blood [D] 2003 Chinese Academy of Sciences Kunming Botany Institute Kunming
27. Q.A. Zheng, H.Z. Li, Y.J. Zhang, and C.R. Yang Dracaenogenins A and B, new spirostanols from the red resin of Dyacaena cochinchinensis Steroids 71 2006 160 164
28. Q.A. Zheng, Y.Z. Zhang, H.Z. Li, and C.R. Yang Steroidal saponins from fresh stem of Dracaena cochinchinensis Steroids 69 2004 111 119
29. Y.D. Zhu, P. Zhang, H.P. Yu, J. Li, M.W. Wang, and W.M. Zhao Anti-helicobacter pylori and thrombin inhibitory components from Chinese Dragon's Blood Dracaena cochinchinensis J. Nat. Prod. 70 2007 1570 1577