Comparative analysis reveals distinct and overlapping functions of Mef2c and Mef2d during cardiogenesis in Xenopus laevis

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Guo, Yanchun ^a   Kühl, Susanne J ^a   Pfister, Astrid S ^a   Cizelsky, Wiebke ^a   Denk, Stephanie ^a   Beer Molz, Laura ^a   Kühl, Michael ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MYOCYTE ENHANCER FACTOR 2; MYOCYTE ENHANCER FACTOR 2C; MYOCYTE ENHANCER FACTOR 2D; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; HEART DEVELOPMENT; HEART EDEMA; MARKER GENE; NONHUMAN; PERICARDIAL EDEMA; XENOPUS LAEVIS;

ANIMALS; GENE EXPRESSION PROFILING; GENE KNOCKDOWN TECHNIQUES; HEART; HEART DEFECTS, CONGENITAL; MEF2 TRANSCRIPTION FACTORS; ORGANOGENESIS; PROTEIN STRUCTURE, TERTIARY; XENOPUS LAEVIS;

EID: 84900314456     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087294     Document Type: Article

References (37)

1. Buckingham M, Meilhac S, Zaffran S (2005) Building the mammalian heart from two sources of myocardial cells. Nat Rev Genet 6: 826-835.
2. Laugwitz KL, Moretti A, Caron L, Nakano A, Chien KR (2008) Islet1 cardiovascular progenitors: a single source for heart lineages? Development 135: 193-205. (Pubitemid 351228412)
3. Srivastava D (2006) Making or breaking the heart: from lineage determination to morphogenesis. Cell 126: 1037-1048.
4. Cai CL, Liang X, Shi Y, Chu PH, Pfaff SL, et al. (2003) Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell 5: 877-889. (Pubitemid 37527688)
5. Kelly RG, Brown NA, Buckingham ME (2001) The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev Cell 1: 435-440. (Pubitemid 33586092)
6. Sater AK, Jacobson AG (1989) The specification of heart mesoderm occurs during gastrulation in Xenopus laevis. Development 105: 821-830. (Pubitemid 19107079)
7. Sater AK, Jacobson AG (1990) The role of the dorsal lip in the induction of heart mesoderm in Xenopus laevis. Development 108: 461-470. (Pubitemid 20105624)
8. Gessert S, Kuhl M (2009) Comparative gene expression analysis and fate mapping studies suggest an early segregation of cardiogenic lineages in Xenopus laevis. Dev Biol 334: 395-408.
9. Molkentin JD, Black BL, Martin JF, Olson EN (1996) Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2C. Mol Cell Biol 16: 2627-2636. (Pubitemid 26161266)
10. Black BL, Olson EN (1998) Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu Rev Cell Dev Biol 14: 167-196. (Pubitemid 29001453)
11. McKinsey TA, Zhang CL, Olson EN (2002) MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends Biochem Sci 27: 40-47. (Pubitemid 34131624)
12. Zhu B, Gulick T (2004) Phosphorylation and alternative pre-mRNA splicing converge to regulate myocyte enhancer factor 2C activity. Mol Cell Biol 24: 8264-8275. (Pubitemid 39167474)
13. della Gaspera B, Armand AS, Sequeira I, Lecolle S, Gallien CL, et al. (2009) The Xenopus MEF2 gene family: evidence of a role for XMEF2C in larval tendon development. Dev Biol 328: 392-402.
14. Lilly B, Zhao B, Ranganayakulu G, Paterson BM, Schulz RA, et al. (1995) Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila. Science 267: 688-693.
15. Edmondson DG, Lyons GE, Martin JF, Olson EN (1994) Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development 120: 1251-1263. (Pubitemid 24150050)
16. Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, et al. (2007) MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell 12: 377-389.
17. Lin Q, Schwarz J, Bucana C, Olson EN (1997) Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science 276: 1404-1407. (Pubitemid 27235406)
18. Naya FJ, Black BL, Wu H, Bassel-Duby R, Richardson JA, et al. (2002) Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat Med 8: 1303-1309. (Pubitemid 35373564)
19. Lin Q, Lu J, Yanagisawa H, Webb R, Lyons GE, et al. (1998) Requirement of the MADS-box transcription factor MEF2C for vascular development. Development 125: 4565-4574. (Pubitemid 28564299)
20. Verzi MP, McCulley DJ, De Val S, Dodou E, Black BL (2005) The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field. Dev Biol 287: 134-145. (Pubitemid 41587484)
21. Vong L, Bi W, O'Connor-Halligan KE, Li C, Cserjesi P, et al. (2006) MEF2C is required for the normal allocation of cells between the ventricular and sinoatrial precursors of the primary heart field. Dev Dyn 235: 1809-1821. (Pubitemid 43902340)
22. Herrmann F, Gross A, Zhou D, Kestler HA, Kuhl M (2012) A boolean model of the cardiac gene regulatory network determining first and second heart field identity. PLoS One 7: e46798.
23. Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, et al. (2012) In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 485: 593-598.
24. Song K, Nam YJ, Luo X, Qi X, Tan W, et al. (2012) Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature 485: 599-604.
25. Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, et al. (2010) Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142: 375-386.
26. Kim Y, Phan D, van Rooij E, Wang DZ, McAnally J, et al. (2008) The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. J Clin Invest 118: 124-132.
27. Moody SA, Kline MJ (1990) Segregation of fate during cleavage of frog (Xenopus laevis) blastomeres. Anat Embryol (Berl) 182: 347-362. (Pubitemid 20331035)
28. Herrmann F, Bundschu K, Kuhl SJ, Kuhl M (2011) Tbx5 overexpression favors a first heart field lineage in murine embryonic stem cells and in Xenopus laevis embryos. Dev Dyn 240: 2634-2645.
29. Karamboulas C, Dakubo GD, Liu J, De Repentigny Y, Yutzey K, et al. (2006) Disruption of MEF2 activity in cardiomyoblasts inhibits cardiomyogenesis. J Cell Sci 119: 4315-4321. (Pubitemid 44774038)
30. Morin S, Charron F, Robitaille L, Nemer M (2000) GATA-dependent recruitment of MEF2 proteins to target promoters. EMBO J 19: 2046-2055. (Pubitemid 30237580)
31. Molkentin JD, Markham BE (1993) Myocyte-specific enhancer-binding factor (MEF-2) regulates alpha-cardiac myosin heavy chain gene expression in vitro and in vivo. J Biol Chem 268: 19512-19520. (Pubitemid 23270734)
32. Di Lisi R, Millino C, Calabria E, Altruda F, Schiaffino S, et al. (1998) Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo. J Biol Chem 273: 25371-25380. (Pubitemid 28443304)
33. Garriock RJ, Meadows SM, Krieg PA (2005) Developmental expression and comparative genomic analysis of Xenopus cardiac myosin heavy chain genes. Dev Dyn 233: 1287-1293. (Pubitemid 40995126)
34. Nieuwkoop P, Faber J (1975) External and internal stage criteria in the development of Xenopus laevis. Elsevier: Amsterdam.
35. Rupp RA, Weintraub H (1991) Ubiquitous MyoD transcription at the midblastula transition precedes induction-dependent MyoD expression in presumptive mesoderm of X. laevis. Cell 65: 927-937. (Pubitemid 121001681)
36. Gessert S, Maurus D, Kuhl M (2008) Repulsive guidance molecule A (RGM A) and its receptor neogenin during neural and neural crest cell development of Xenopus laevis. Biol Cell 100: 659-673.
37. Hemmati-Brivanlou A, Frank D, Bolce ME, Brown BD, Sive HL, et al. (1990) Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization. Development 110: 325-330. (Pubitemid 20330508)