An integrated strategy based on UPLC-DAD-QTOF-MS for metabolism and pharmacokinetic studies of herbal medicines: Tibetan "snow Lotus" herb (Saussurea laniceps), a case study

Journal of Ethnopharmacology

Volumn 153, Issue 3, 2014, Pages 701-713

  Yi, Tao ^a   Zhu, Lin ^b   Tang, Yi Na ^a   Zhang, Jian Ye ^a   Liang, Zhi Tao ^a   Xu, Jun ^a   Zhao, Zhong Zhen ^a   Yu, Zhi Ling ^a   Bian, Zhao Xiang ^a   Yang, Zhi Jun ^a   Chen, Hu Biao ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Herbal medicine; Metabolism; Pharmacokinetics; Saussurea laniceps; Snow lotus; UPLC DAD QTOF MS

Indexed keywords

CHLOROGENIC ACID; GLUCOSIDE; HERBACEOUS AGENT; QUINIC ACID; SAUSSUREA LANICEPS PLANT EXTRACT; SCOPOLETIN; SYRINGIN; UMBELLIFERONE; UNCLASSIFIED DRUG; 7-HYDROXYCOUMARIN; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; UMBELLIFERONE DERIVATIVE;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG FECES LEVEL; DRUG METABOLISM; DRUG TRANSFORMATION; DRUG URINE LEVEL; FEASIBILITY STUDY; HERBAL MEDICINE; MALE; NONHUMAN; RAT; SAUSSUREA; SAUSSUREA LANICEPS; THERAPY EFFECT; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY DIODE ARRAY DETECTION QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; VALIDITY; ANIMAL; ASTERACEAE; BLOOD; CHEMISTRY; FECES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROCEDURES; SPRAGUE DAWLEY RAT; TRADITIONAL MEDICINE; URINE;

RATTUS; SAUSSUREA LANICEPS;

ANIMALS; ASTERACEAE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FECES; MALE; MASS SPECTROMETRY; MEDICINE, TRADITIONAL; PHYTOCHEMICALS; PLANT EXTRACTS; RATS, SPRAGUE-DAWLEY; SCOPOLETIN; UMBELLIFERONES;

EID: 84900310371     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.03.031     Document Type: Article

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