Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: Critical role of p38MAPK

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 298, Issue 4, 2010, Pages

  Singh, Pomila ^a   Sarkar, Shubhashish ^a   Umar, Shahid ^a   Rengifo Cam, William ^a   Singh, Amar P ^a   Wood, Thomas G ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

c Src; Caco 2 cells; IEC 18 cells; NF B

Indexed keywords

CURCUMIN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROGASTRIN; SOMATOMEDIN B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CELL PROTECTION; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WILD TYPE;

ANIMALS; ANTIBODIES; APOPTOSIS; AUTOCRINE COMMUNICATION; CACO-2 CELLS; CAMPTOTHECIN; CASPASE 3; CASPASE 9; CELL LINE; CELL PROLIFERATION; CURCUMIN; EPITHELIAL CELLS; GASTRINS; HUMANS; I-KAPPA B KINASE; ILEUM; IMIDAZOLES; INSULIN-LIKE GROWTH FACTOR II; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PRECURSORS; PROTEIN-TYROSINE KINASES; PYRIDINES; RATS; SOMATOMEDINS; TRANSCRIPTION FACTOR RELA; TRANSFECTION;

EID: 77950292976     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00497.2009     Document Type: Article

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