메뉴 건너뛰기




Volumn 11, Issue , 2014, Pages

Heat shock protein 60: An endogenous inducer of dopaminergic cell death in Parkinson disease

Author keywords

Hsp60; Innate immunity; Microglia; Neurodegeneration; Neuroinflammation; PD

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CHAPERONIN 60; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MESSENGER RNA; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; DOPAMINE RECEPTOR STIMULATING AGENT; PROTEIN BINDING; TYROSINE 3 MONOOXYGENASE;

EID: 84899999860     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-11-86     Document Type: Article
Times cited : (38)

References (57)
  • 1
    • 0003148419 scopus 로고    scopus 로고
    • Parkinsonism
    • New York: Lippincott, Rowland LP, 10
    • Fahn SPS. Parkinsonism. Meritt's Neurology 2000, 679-693. New York: Lippincott, Rowland LP, 10.
    • (2000) Meritt's Neurology , pp. 679-693
    • Fahn, S.P.S.1
  • 2
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: a target for neuroprotection?
    • 10.1016/S1474-4422(09)70062-6, 19296921
    • Hirsch EC, Hunot S. Neuroinflammation in Parkinson's disease: a target for neuroprotection?. Lancet Neurol 2009, 8:382-397. 10.1016/S1474-4422(09)70062-6, 19296921.
    • (2009) Lancet Neurol , vol.8 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 3
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • 10.1212/WNL.38.8.1285, 3399080
    • McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988, 38:1285-1291. 10.1212/WNL.38.8.1285, 3399080.
    • (1988) Neurology , vol.38 , pp. 1285-1291
    • McGeer, P.L.1    Itagaki, S.2    Boyes, B.E.3    McGeer, E.G.4
  • 5
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
    • 10.1002/1531-8249(199910)46:4<598::AID-ANA7>3.0.CO;2-F, 10514096
    • Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D. Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol 1999, 46:598-605. 10.1002/1531-8249(199910)46:4<598::AID-ANA7>3.0.CO;2-F, 10514096.
    • (1999) Ann Neurol , vol.46 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3    Reeves, A.G.4    Kaplan, J.A.5    Karluk, D.6
  • 6
    • 0242384667 scopus 로고    scopus 로고
    • Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration
    • 10.1002/ana.10728, 14595649
    • McGeer PL, Schwab C, Parent A, Doudet D. Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. Ann Neurol 2003, 54:599-604. 10.1002/ana.10728, 14595649.
    • (2003) Ann Neurol , vol.54 , pp. 599-604
    • McGeer, P.L.1    Schwab, C.2    Parent, A.3    Doudet, D.4
  • 7
    • 0035170282 scopus 로고    scopus 로고
    • Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components
    • 10.1096/fj.00-0339com, 11149903
    • Laflamme N, Rivest S. Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. Faseb J 2001, 15:155-163. 10.1096/fj.00-0339com, 11149903.
    • (2001) Faseb J , vol.15 , pp. 155-163
    • Laflamme, N.1    Rivest, S.2
  • 8
    • 20544474210 scopus 로고    scopus 로고
    • Pathogen recognition with Toll-like receptors
    • 10.1016/j.coi.2005.02.007, 15950447
    • Kawai T, Akira S. Pathogen recognition with Toll-like receptors. Curr Opin Immunol 2005, 17:338-344. 10.1016/j.coi.2005.02.007, 15950447.
    • (2005) Curr Opin Immunol , vol.17 , pp. 338-344
    • Kawai, T.1    Akira, S.2
  • 9
    • 4344627821 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors
    • 10.1189/jlb.0304127, 15178705
    • Tsan MF, Gao B. Endogenous ligands of Toll-like receptors. J Leukoc Biol 2004, 76:514-519. 10.1189/jlb.0304127, 15178705.
    • (2004) J Leukoc Biol , vol.76 , pp. 514-519
    • Tsan, M.F.1    Gao, B.2
  • 10
    • 77954005130 scopus 로고    scopus 로고
    • Endogenous ligands of TLR2 and TLR4: agonists or assistants?
    • 10.1189/jlb.1209775, 20179153
    • Erridge C. Endogenous ligands of TLR2 and TLR4: agonists or assistants?. J Leukoc Biol 2010, 87:989-999. 10.1189/jlb.1209775, 20179153.
    • (2010) J Leukoc Biol , vol.87 , pp. 989-999
    • Erridge, C.1
  • 11
    • 0033104877 scopus 로고    scopus 로고
    • Heat-shock protein protection
    • 10.1016/S0166-2236(98)01392-7, 10199631
    • Sharp FR, Massa SM, Swanson RA. Heat-shock protein protection. Trends Neurosci 1999, 22:97-99. 10.1016/S0166-2236(98)01392-7, 10199631.
    • (1999) Trends Neurosci , vol.22 , pp. 97-99
    • Sharp, F.R.1    Massa, S.M.2    Swanson, R.A.3
  • 12
    • 0037783960 scopus 로고    scopus 로고
    • Stress-induced release of HSC70 from human tumors
    • 10.1016/S0008-8749(03)00115-1, 12826079
    • Barreto A, Gonzalez JM, Kabingu E, Asea A, Fiorentino S. Stress-induced release of HSC70 from human tumors. Cell Immunol 2003, 222:97-104. 10.1016/S0008-8749(03)00115-1, 12826079.
    • (2003) Cell Immunol , vol.222 , pp. 97-104
    • Barreto, A.1    Gonzalez, J.M.2    Kabingu, E.3    Asea, A.4    Fiorentino, S.5
  • 14
    • 61549130869 scopus 로고    scopus 로고
    • Heat-shock proteins can promote as well as regulate autoimmunity
    • 10.1016/j.autrev.2008.12.004, 2668694, 19121415
    • Rajaiah R, Moudgil KD. Heat-shock proteins can promote as well as regulate autoimmunity. Autoimmun Rev 2009, 8:388-393. 10.1016/j.autrev.2008.12.004, 2668694, 19121415.
    • (2009) Autoimmun Rev , vol.8 , pp. 388-393
    • Rajaiah, R.1    Moudgil, K.D.2
  • 15
    • 37049004489 scopus 로고    scopus 로고
    • Mitochondria in the aetiology and pathogenesis of Parkinson's disease
    • 10.1016/S1474-4422(07)70327-7, 18093566
    • Schapira AH. Mitochondria in the aetiology and pathogenesis of Parkinson's disease. Lancet Neurol 2008, 7:97-109. 10.1016/S1474-4422(07)70327-7, 18093566.
    • (2008) Lancet Neurol , vol.7 , pp. 97-109
    • Schapira, A.H.1
  • 16
    • 18844369636 scopus 로고    scopus 로고
    • Detection of HSP60 on the membrane surface of stressed human endothelial cells by atomic force and confocal microscopy
    • 10.1242/jcs.02292, 15784682
    • Pfister G, Stroh CM, Perschinka H, Kind M, Knoflach M, Hinterdorfer P, Wick G. Detection of HSP60 on the membrane surface of stressed human endothelial cells by atomic force and confocal microscopy. J Cell Sci 2005, 118:1587-1594. 10.1242/jcs.02292, 15784682.
    • (2005) J Cell Sci , vol.118 , pp. 1587-1594
    • Pfister, G.1    Stroh, C.M.2    Perschinka, H.3    Kind, M.4    Knoflach, M.5    Hinterdorfer, P.6    Wick, G.7
  • 17
    • 0033401220 scopus 로고    scopus 로고
    • Spontaneous apoptosis and expression of cell surface heat-shock proteins in cultured EL-4 lymphoma cells
    • 10.1111/j.1365-2184.1999.tb01354.x, 10646688
    • Sapozhnikov AM, Ponomarev ED, Tarasenko TN, Telford WG. Spontaneous apoptosis and expression of cell surface heat-shock proteins in cultured EL-4 lymphoma cells. Cell Prolif 1999, 32:363-378. 10.1111/j.1365-2184.1999.tb01354.x, 10646688.
    • (1999) Cell Prolif , vol.32 , pp. 363-378
    • Sapozhnikov, A.M.1    Ponomarev, E.D.2    Tarasenko, T.N.3    Telford, W.G.4
  • 18
    • 0034650427 scopus 로고    scopus 로고
    • Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
    • 10.4049/jimmunol.164.2.558, 10623794
    • Ohashi K, Burkart V, Flohe S, Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 2000, 164:558-561. 10.4049/jimmunol.164.2.558, 10623794.
    • (2000) J Immunol , vol.164 , pp. 558-561
    • Ohashi, K.1    Burkart, V.2    Flohe, S.3    Kolb, H.4
  • 19
    • 40449097556 scopus 로고    scopus 로고
    • A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS
    • 10.1523/JNEUROSCI.4760-07.2008, 18322079
    • Lehnardt S, Schott E, Trimbuch T, Laubisch D, Krueger C, Wulczyn G, Nitsch R, Weber JR. A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS. J Neurosci 2008, 28:2320-2331. 10.1523/JNEUROSCI.4760-07.2008, 18322079.
    • (2008) J Neurosci , vol.28 , pp. 2320-2331
    • Lehnardt, S.1    Schott, E.2    Trimbuch, T.3    Laubisch, D.4    Krueger, C.5    Wulczyn, G.6    Nitsch, R.7    Weber, J.R.8
  • 20
    • 34347259269 scopus 로고    scopus 로고
    • Protocol for the MPTP mouse model of Parkinson's disease
    • 10.1038/nprot.2006.342, 17401348
    • Jackson-Lewis V, Przedborski S. Protocol for the MPTP mouse model of Parkinson's disease. Nat Protoc 2007, 2:141-151. 10.1038/nprot.2006.342, 17401348.
    • (2007) Nat Protoc , vol.2 , pp. 141-151
    • Jackson-Lewis, V.1    Przedborski, S.2
  • 21
    • 0022480636 scopus 로고
    • The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice
    • 10.1016/0014-2999(86)90444-9, 3490988
    • Sonsalla PK, Heikkila RE. The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice. Eur J Pharmacol 1986, 129:339-345. 10.1016/0014-2999(86)90444-9, 3490988.
    • (1986) Eur J Pharmacol , vol.129 , pp. 339-345
    • Sonsalla, P.K.1    Heikkila, R.E.2
  • 22
    • 0028817640 scopus 로고
    • Abnormally phosphorylated tau in SY5Y human neuroblastoma cells
    • 10.1016/0014-5793(95)00061-D, 7875300
    • Tanaka T, Iqbal K, Trenkner E, Liu DJ, Grundke-Iqbal I. Abnormally phosphorylated tau in SY5Y human neuroblastoma cells. FEBS Lett 1995, 360:5-9. 10.1016/0014-5793(95)00061-D, 7875300.
    • (1995) FEBS Lett , vol.360 , pp. 5-9
    • Tanaka, T.1    Iqbal, K.2    Trenkner, E.3    Liu, D.J.4    Grundke-Iqbal, I.5
  • 23
    • 0035283217 scopus 로고    scopus 로고
    • Low concentrations of 1-methyl-4-phenylpyridinium ion induce caspase-mediated apoptosis in human SH-SY5Y neuroblastoma cells
    • 10.1002/1097-4547(20010301)63:5<421::AID-JNR1037>3.0.CO;2-4, 11223917
    • Gomez C, Reiriz J, Pique M, Gil J, Ferrer I, Ambrosio S. Low concentrations of 1-methyl-4-phenylpyridinium ion induce caspase-mediated apoptosis in human SH-SY5Y neuroblastoma cells. J Neurosci Res 2001, 63:421-428. 10.1002/1097-4547(20010301)63:5<421::AID-JNR1037>3.0.CO;2-4, 11223917.
    • (2001) J Neurosci Res , vol.63 , pp. 421-428
    • Gomez, C.1    Reiriz, J.2    Pique, M.3    Gil, J.4    Ferrer, I.5    Ambrosio, S.6
  • 24
    • 0029830647 scopus 로고    scopus 로고
    • Chronic activation of the cyclic AMP signaling pathway promotes development and long-term survival of mesencephalic dopaminergic neurons
    • Michel PP, Agid Y. Chronic activation of the cyclic AMP signaling pathway promotes development and long-term survival of mesencephalic dopaminergic neurons. J Neurochem 1996, 67:1633-1642.
    • (1996) J Neurochem , vol.67 , pp. 1633-1642
    • Michel, P.P.1    Agid, Y.2
  • 25
    • 3042789539 scopus 로고    scopus 로고
    • Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels
    • 10.1523/JNEUROSCI.5668-03.2004, 15229240
    • Salthun-Lassalle B, Hirsch EC, Wolfart J, Ruberg M, Michel PP. Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels. J Neurosci 2004, 24:5922-5930. 10.1523/JNEUROSCI.5668-03.2004, 15229240.
    • (2004) J Neurosci , vol.24 , pp. 5922-5930
    • Salthun-Lassalle, B.1    Hirsch, E.C.2    Wolfart, J.3    Ruberg, M.4    Michel, P.P.5
  • 26
    • 0025265681 scopus 로고
    • Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II
    • Knusel B, Michel PP, Schwaber JS, Hefti F. Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II. J Neurosci 1990, 10:558-570.
    • (1990) J Neurosci , vol.10 , pp. 558-570
    • Knusel, B.1    Michel, P.P.2    Schwaber, J.S.3    Hefti, F.4
  • 27
    • 0022489477 scopus 로고
    • Cryopreservation of primary neurons for tissue culture
    • 10.1016/0006-8993(86)91222-9, 3791002
    • Kawamoto JC, Barrett JN. Cryopreservation of primary neurons for tissue culture. Brain Res 1986, 384:84-93. 10.1016/0006-8993(86)91222-9, 3791002.
    • (1986) Brain Res , vol.384 , pp. 84-93
    • Kawamoto, J.C.1    Barrett, J.N.2
  • 28
    • 0041353623 scopus 로고    scopus 로고
    • Prevention of dopaminergic neuronal death by cyclic AMP in mixed neuronal/glial mesencephalic cultures requires the repression of presumptive astrocytes
    • 10.1124/mol.64.3.578, 12920193
    • Mourlevat S, Troadec JD, Ruberg M, Michel PP. Prevention of dopaminergic neuronal death by cyclic AMP in mixed neuronal/glial mesencephalic cultures requires the repression of presumptive astrocytes. Mol Pharmacol 2003, 64:578-586. 10.1124/mol.64.3.578, 12920193.
    • (2003) Mol Pharmacol , vol.64 , pp. 578-586
    • Mourlevat, S.1    Troadec, J.D.2    Ruberg, M.3    Michel, P.P.4
  • 29
    • 0025278873 scopus 로고
    • Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility
    • 10.1111/j.1471-4159.1990.tb01935.x, 1968953
    • Michel PP, Dandapani BK, Knusel B, Sanchez-Ramos J, Hefti F. Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility. J Neurochem 1990, 54:1102-1109. 10.1111/j.1471-4159.1990.tb01935.x, 1968953.
    • (1990) J Neurochem , vol.54 , pp. 1102-1109
    • Michel, P.P.1    Dandapani, B.K.2    Knusel, B.3    Sanchez-Ramos, J.4    Hefti, F.5
  • 30
    • 0344013138 scopus 로고    scopus 로고
    • High-yield isolation of murine microglia by mild trypsinization
    • 10.1002/glia.10274, 14603460
    • Saura J, Tusell JM, Serratosa J. High-yield isolation of murine microglia by mild trypsinization. Glia 2003, 44:183-189. 10.1002/glia.10274, 14603460.
    • (2003) Glia , vol.44 , pp. 183-189
    • Saura, J.1    Tusell, J.M.2    Serratosa, J.3
  • 31
    • 0029175202 scopus 로고
    • Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
    • Mattson MP, Barger SW, Begley JG, Mark RJ. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol 1995, 46:187-216.
    • (1995) Methods Cell Biol , vol.46 , pp. 187-216
    • Mattson, M.P.1    Barger, S.W.2    Begley, J.G.3    Mark, R.J.4
  • 32
    • 84934444135 scopus 로고    scopus 로고
    • Cell sensitivity assays: the MTT assay
    • 10.1007/978-1-61779-080-5_20, 21516412
    • Van Meerloo J, Kaspers GJ, Cloos J. Cell sensitivity assays: the MTT assay. Methods Mol Biol 2011, 731:237-245. 10.1007/978-1-61779-080-5_20, 21516412.
    • (2011) Methods Mol Biol , vol.731 , pp. 237-245
    • Van Meerloo, J.1    Kaspers, G.J.2    Cloos, J.3
  • 33
    • 84867142929 scopus 로고    scopus 로고
    • MTT assay for cell viability: intracellular localization of the formazan product is in lipid droplets
    • 10.1016/j.acthis.2012.01.006, 22341561
    • Stockert JC, Blazquez-Castro A, Canete M, Horobin RW, Villanueva A. MTT assay for cell viability: intracellular localization of the formazan product is in lipid droplets. Acta Histochem 2012, 114:785-796. 10.1016/j.acthis.2012.01.006, 22341561.
    • (2012) Acta Histochem , vol.114 , pp. 785-796
    • Stockert, J.C.1    Blazquez-Castro, A.2    Canete, M.3    Horobin, R.W.4    Villanueva, A.5
  • 34
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • 10.1038/35100529, 11905821
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001, 1:135-145. 10.1038/35100529, 11905821.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 36
    • 0029098592 scopus 로고
    • Improved detection of nitric oxide radical (NO.) production in an activated macrophage culture with a radical scavenger, carboxy PTIO and Griess reagent
    • 10.1016/0014-5793(95)00700-J, 7543422
    • Amano F, Noda T. Improved detection of nitric oxide radical (NO.) production in an activated macrophage culture with a radical scavenger, carboxy PTIO and Griess reagent. FEBS Lett 1995, 368:425-428. 10.1016/0014-5793(95)00700-J, 7543422.
    • (1995) FEBS Lett , vol.368 , pp. 425-428
    • Amano, F.1    Noda, T.2
  • 37
    • 84862816077 scopus 로고    scopus 로고
    • High-dose clevudine impairs mitochondrial function and glucose-stimulated insulin secretion in INS-1E cells
    • 10.1186/1471-230X-12-4, 3288815, 22230186
    • Jang YO, Quan X, Das R, Xu S, Chung CH, Ahn CM, Baik SK, Kong ID, Park KS, Kim MY. High-dose clevudine impairs mitochondrial function and glucose-stimulated insulin secretion in INS-1E cells. BMC Gastroenterol 2012, 12:4. 10.1186/1471-230X-12-4, 3288815, 22230186.
    • (2012) BMC Gastroenterol , vol.12 , pp. 4
    • Jang, Y.O.1    Quan, X.2    Das, R.3    Xu, S.4    Chung, C.H.5    Ahn, C.M.6    Baik, S.K.7    Kong, I.D.8    Park, K.S.9    Kim, M.Y.10
  • 38
    • 0030885416 scopus 로고    scopus 로고
    • Rescue of mesencephalic dopamine neurons by anticancer drug cytosine arabinoside
    • Michel PP, Ruberg M, Agid Y. Rescue of mesencephalic dopamine neurons by anticancer drug cytosine arabinoside. J Neurochem 1997, 69:1499-1507.
    • (1997) J Neurochem , vol.69 , pp. 1499-1507
    • Michel, P.P.1    Ruberg, M.2    Agid, Y.3
  • 39
    • 0037080218 scopus 로고    scopus 로고
    • The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins
    • 10.4049/jimmunol.168.2.569, 11777948
    • Habich C, Baumgart K, Kolb H, Burkart V. The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins. J Immunol 2002, 168:569-576. 10.4049/jimmunol.168.2.569, 11777948.
    • (2002) J Immunol , vol.168 , pp. 569-576
    • Habich, C.1    Baumgart, K.2    Kolb, H.3    Burkart, V.4
  • 40
    • 0035903158 scopus 로고    scopus 로고
    • Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells
    • 10.1074/jbc.M103217200, 11402040
    • Vabulas RM, Ahmad-Nejad P, da Costa C, Miethke T, Kirschning CJ, Hacker H, Wagner H. Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. J Biol Chem 2001, 276:31332-31339. 10.1074/jbc.M103217200, 11402040.
    • (2001) J Biol Chem , vol.276 , pp. 31332-31339
    • Vabulas, R.M.1    Ahmad-Nejad, P.2    da Costa, C.3    Miethke, T.4    Kirschning, C.J.5    Hacker, H.6    Wagner, H.7
  • 41
    • 33947510303 scopus 로고    scopus 로고
    • Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide
    • 10.1074/jbc.M608666200, 17164250
    • Osterloh A, Kalinke U, Weiss S, Fleischer B, Breloer M. Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide. J Biol Chem 2007, 282:4669-4680. 10.1074/jbc.M608666200, 17164250.
    • (2007) J Biol Chem , vol.282 , pp. 4669-4680
    • Osterloh, A.1    Kalinke, U.2    Weiss, S.3    Fleischer, B.4    Breloer, M.5
  • 42
    • 0027925653 scopus 로고
    • Heat shock proteins functioning as molecular chaperones: their roles in normal and stressed cells
    • 10.1098/rstb.1993.0031, 8098537
    • Welch WJ. Heat shock proteins functioning as molecular chaperones: their roles in normal and stressed cells. Philos Trans R Soc Lond B Biol Sci 1993, 339:327-333. 10.1098/rstb.1993.0031, 8098537.
    • (1993) Philos Trans R Soc Lond B Biol Sci , vol.339 , pp. 327-333
    • Welch, W.J.1
  • 43
    • 79751531096 scopus 로고    scopus 로고
    • The HSP60 immune system network
    • 10.1016/j.it.2010.11.001, 21145789
    • Quintana FJ, Cohen IR. The HSP60 immune system network. Trends Immunol 2011, 32:89-95. 10.1016/j.it.2010.11.001, 21145789.
    • (2011) Trends Immunol , vol.32 , pp. 89-95
    • Quintana, F.J.1    Cohen, I.R.2
  • 44
    • 0034937409 scopus 로고    scopus 로고
    • Heat shock proteins as 'danger signals': eukaryotic Hsp60 enhances and accelerates antigen-specific IFN-gamma production in T cells
    • 10.1002/1521-4141(200107)31:7<2051::AID-IMMU2051>3.0.CO;2-H, 11449358
    • Breloer M, Dorner B, More SH, Roderian T, Fleischer B, von Bonin A. Heat shock proteins as 'danger signals': eukaryotic Hsp60 enhances and accelerates antigen-specific IFN-gamma production in T cells. Eur J Immunol 2001, 31:2051-2059. 10.1002/1521-4141(200107)31:7<2051::AID-IMMU2051>3.0.CO;2-H, 11449358.
    • (2001) Eur J Immunol , vol.31 , pp. 2051-2059
    • Breloer, M.1    Dorner, B.2    More, S.H.3    Roderian, T.4    Fleischer, B.5    von Bonin, A.6
  • 45
    • 0033559496 scopus 로고    scopus 로고
    • Human 60-kDa heat-shock protein: a danger signal to the innate immune system
    • Chen W, Syldath U, Bellmann K, Burkart V, Kolb H. Human 60-kDa heat-shock protein: a danger signal to the innate immune system. J Immunol 1999, 162:3212-3219.
    • (1999) J Immunol , vol.162 , pp. 3212-3219
    • Chen, W.1    Syldath, U.2    Bellmann, K.3    Burkart, V.4    Kolb, H.5
  • 46
    • 0035139983 scopus 로고    scopus 로고
    • Danger signals: SOS to the immune system
    • 10.1016/S0952-7915(00)00191-6, 11154927
    • Gallucci S, Matzinger P. Danger signals: SOS to the immune system. Curr Opin Immunol 2001, 13:114-119. 10.1016/S0952-7915(00)00191-6, 11154927.
    • (2001) Curr Opin Immunol , vol.13 , pp. 114-119
    • Gallucci, S.1    Matzinger, P.2
  • 47
  • 50
    • 84872595532 scopus 로고    scopus 로고
    • Toll-like receptor 4 is required for alpha-synuclein dependent activation of microglia and astroglia
    • 10.1002/glia.22437, 3568908, 23108585
    • Fellner L, Irschick R, Schanda K, Reindl M, Klimaschewski L, Poewe W, Wenning GK, Stefanova N. Toll-like receptor 4 is required for alpha-synuclein dependent activation of microglia and astroglia. Glia 2013, 61:349-360. 10.1002/glia.22437, 3568908, 23108585.
    • (2013) Glia , vol.61 , pp. 349-360
    • Fellner, L.1    Irschick, R.2    Schanda, K.3    Reindl, M.4    Klimaschewski, L.5    Poewe, W.6    Wenning, G.K.7    Stefanova, N.8
  • 51
    • 84895927382 scopus 로고    scopus 로고
    • Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy
    • 10.1111/jnc.12516, 24261962
    • Jayakumar AR, Tong XY, Curtis KM, Ruiz-Cordero R, Abreu MT, Norenberg MD. Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy. J Neurochem 2014, 128:890-903. 10.1111/jnc.12516, 24261962.
    • (2014) J Neurochem , vol.128 , pp. 890-903
    • Jayakumar, A.R.1    Tong, X.Y.2    Curtis, K.M.3    Ruiz-Cordero, R.4    Abreu, M.T.5    Norenberg, M.D.6
  • 52
    • 84899461458 scopus 로고    scopus 로고
    • LPS or ethanol triggers clathrin- and rafts/caveolae-dependent endocytosis of TLR4 in cortical astrocytes
    • 10.1111/jnc.12639, 24345077
    • Pascual-Lucas M, Fernandez-Lizarbe S, Montesinos J, Guerri C. LPS or ethanol triggers clathrin- and rafts/caveolae-dependent endocytosis of TLR4 in cortical astrocytes. J Neurochem 2014, 129:448-462. 10.1111/jnc.12639, 24345077.
    • (2014) J Neurochem , vol.129 , pp. 448-462
    • Pascual-Lucas, M.1    Fernandez-Lizarbe, S.2    Montesinos, J.3    Guerri, C.4
  • 53
    • 84898051513 scopus 로고    scopus 로고
    • LPS and IL-1 differentially activate mouse and human astrocytes: role of CD14
    • 10.1002/glia.22657, 24659539
    • Tarassishin L, Suh HS, Lee SC. LPS and IL-1 differentially activate mouse and human astrocytes: role of CD14. Glia 2014, 62:999-1013. 10.1002/glia.22657, 24659539.
    • (2014) Glia , vol.62 , pp. 999-1013
    • Tarassishin, L.1    Suh, H.S.2    Lee, S.C.3
  • 54
    • 0345074067 scopus 로고    scopus 로고
    • Human heat shock protein 60 induces maturation of dendritic cells versus a Th1-promoting phenotype
    • 10.4049/jimmunol.170.5.2340, 12594256
    • Flohe SB, Bruggemann J, Lendemans S, Nikulina M, Meierhoff G, Flohe S, Kolb H. Human heat shock protein 60 induces maturation of dendritic cells versus a Th1-promoting phenotype. J Immunol 2003, 170:2340-2348. 10.4049/jimmunol.170.5.2340, 12594256.
    • (2003) J Immunol , vol.170 , pp. 2340-2348
    • Flohe, S.B.1    Bruggemann, J.2    Lendemans, S.3    Nikulina, M.4    Meierhoff, G.5    Flohe, S.6    Kolb, H.7
  • 55
    • 0033975855 scopus 로고    scopus 로고
    • Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells
    • 10.4049/jimmunol.164.1.13, 10604986
    • Kol A, Lichtman AH, Finberg RW, Libby P, Kurt-Jones EA. Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. J Immunol 2000, 164:13-17. 10.4049/jimmunol.164.1.13, 10604986.
    • (2000) J Immunol , vol.164 , pp. 13-17
    • Kol, A.1    Lichtman, A.H.2    Finberg, R.W.3    Libby, P.4    Kurt-Jones, E.A.5
  • 56
    • 40049104675 scopus 로고    scopus 로고
    • Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12
    • 10.1093/intimm/dxn003, 18256040
    • Osterloh A, Veit A, Gessner A, Fleischer B, Breloer M. Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12. Int Immunol 2008, 20:433-443. 10.1093/intimm/dxn003, 18256040.
    • (2008) Int Immunol , vol.20 , pp. 433-443
    • Osterloh, A.1    Veit, A.2    Gessner, A.3    Fleischer, B.4    Breloer, M.5
  • 57
    • 84870062167 scopus 로고    scopus 로고
    • Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity
    • 10.1016/j.neuint.2012.07.019, 22847064
    • Zhang D, Sun L, Zhu H, Wang L, Wu W, Xie J, Gu J. Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity. Neurochem Int 2012, 61:1021-1035. 10.1016/j.neuint.2012.07.019, 22847064.
    • (2012) Neurochem Int , vol.61 , pp. 1021-1035
    • Zhang, D.1    Sun, L.2    Zhu, H.3    Wang, L.4    Wu, W.5    Xie, J.6    Gu, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.