메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

Pretreatment with Saccharomyces boulardii does not prevent the experimental mucositis in Swiss mice

Author keywords

5 fluorouracil; Intestinal permeability; Mucositis; Probiotic; Saccharomyces boulardii

Indexed keywords

PROBIOTIC AGENT; SECRETORY IMMUNOGLOBULIN;

EID: 84899985789     PISSN: None     EISSN: 14775751     Source Type: Journal    
DOI: 10.1186/1477-5751-13-6     Document Type: Article
Times cited : (37)

References (42)
  • 1
    • 84868500395 scopus 로고    scopus 로고
    • Probiotic factors partially prevent changes to caspases 3 and 7 activation and transepithelial electrical resistance in a model of 5-fluorouracil-induced epithelial cell damage
    • 10.1007/s00520-012-1446-3 22526145
    • Probiotic factors partially prevent changes to caspases 3 and 7 activation and transepithelial electrical resistance in a model of 5-fluorouracil-induced epithelial cell damage. Prisciandaro LD, Geier MS, Chua AE, Butler RN, Cummins AG, Sander GR, Howarth GS, Support Care Cancer 2012 20 3205 3210 10.1007/s00520-012-1446-3 22526145
    • (2012) Support Care Cancer , vol.20 , pp. 3205-3210
    • Prisciandaro, L.D.1    Geier, M.S.2    Chua, A.E.3    Butler, R.N.4    Cummins, A.G.5    Sander, G.R.6    Howarth, G.S.7
  • 2
    • 33748475133 scopus 로고    scopus 로고
    • Cancer treatment-induced mucositis pain: Strategies for assessment and management
    • 10.2147/tcrm.2006.2.3.251 18360600
    • Cancer treatment-induced mucositis pain: strategies for assessment and management. Harris DJ, Ther Clin Risk Manag 2006 2 251 258 10.2147/tcrm.2006.2. 3.251 18360600
    • (2006) Ther Clin Risk Manag , vol.2 , pp. 251-258
    • Harris, D.J.1
  • 3
    • 14944363195 scopus 로고    scopus 로고
    • Antitumour activity of XR5944 in vitro and in vivo in combination with 5-fluorouracil and irinotecan in colon cancer cell lines
    • 10.1038/sj.bjc.6602403 15700035
    • Antitumour activity of XR5944 in vitro and in vivo in combination with 5-fluorouracil and irinotecan in colon cancer cell lines. Harris SM, Mistry P, Freathy C, Brown JL, Charlton PA, Br J Cancer 2005 92 722 728 10.1038/sj.bjc.6602403 15700035
    • (2005) Br J Cancer , vol.92 , pp. 722-728
    • Harris, S.M.1    Mistry, P.2    Freathy, C.3    Brown, J.L.4    Charlton, P.A.5
  • 4
    • 77955611551 scopus 로고    scopus 로고
    • Effects of low-level laser therapy on collagen expression and neutrophil infiltrate in 5-fluorouracil-induced oral mucositis in hamsters
    • 10.1002/lsm.20920 20662031
    • Effects of low-level laser therapy on collagen expression and neutrophil infiltrate in 5-fluorouracil-induced oral mucositis in hamsters. Lopes NN, Plapler H, Lalla RV, Chavantes MC, Yoshimura EM, da Silva MA, Alves MT, Lasers Surg Med 2010 42 546 552 10.1002/lsm.20920 20662031
    • (2010) Lasers Surg Med , vol.42 , pp. 546-552
    • Lopes, N.N.1    Plapler, H.2    Lalla, R.V.3    Chavantes, M.C.4    Yoshimura, E.M.5    Da Silva, M.A.6    Alves, M.T.7
  • 5
    • 33747364771 scopus 로고    scopus 로고
    • Cancer chemotherapy-induced diarrhoea and constipation: Mechanisms of damage and prevention strategies
    • 10.1007/s00520-006-0040-y 16604351
    • Cancer chemotherapy-induced diarrhoea and constipation: mechanisms of damage and prevention strategies. Gibson RJ, Keefe DM, Support Care Cancer 2006 14 890 900 10.1007/s00520-006-0040-y 16604351
    • (2006) Support Care Cancer , vol.14 , pp. 890-900
    • Gibson, R.J.1    Keefe, D.M.2
  • 6
    • 33751120388 scopus 로고    scopus 로고
    • The combination of oral and small intestinal mucositis, pediatrics and biomarkers: A particularly tricky problem!
    • 10.4161/cbt.5.10.3508 17172807
    • The combination of oral and small intestinal mucositis, pediatrics and biomarkers: a particularly tricky problem! Keefe DM, Gibson RJ, Cancer Biol Ther 2006 5 1282 1284 10.4161/cbt.5.10.3508 17172807
    • (2006) Cancer Biol Ther , vol.5 , pp. 1282-1284
    • Keefe, D.M.1    Gibson, R.J.2
  • 7
    • 0037294291 scopus 로고    scopus 로고
    • Risk factors for ulcerative oral mucositis in cancer patients: Unanswered questions
    • 10.1016/S1368-8375(02)00033-7 12509961
    • Risk factors for ulcerative oral mucositis in cancer patients: unanswered questions. Barasch A, Peterson DE, Oral Oncol 2003 39 91 100 10.1016/S1368-8375(02)00033-7 12509961
    • (2003) Oral Oncol , vol.39 , pp. 91-100
    • Barasch, A.1    Peterson, D.E.2
  • 8
    • 0346102609 scopus 로고    scopus 로고
    • Oral mucositis: A challenging complication of radiotherapy, chemotherapy, and radiochemotherapy. Part 2: Diagnosis and management of mucositis
    • 10.1002/hed.10326 14724910
    • Oral mucositis: a challenging complication of radiotherapy, chemotherapy, and radiochemotherapy. Part 2: diagnosis and management of mucositis. Scully C, Epstein J, Sonis S, Head Neck 2004 26 77 84 10.1002/hed.10326 14724910
    • (2004) Head Neck , vol.26 , pp. 77-84
    • Scully, C.1    Epstein, J.2    Sonis, S.3
  • 9
    • 0033214189 scopus 로고    scopus 로고
    • 5-fluorouracil-induced small bowel toxicity in patients with colorectal carcinoma
    • 10.1002/(SICI)1097-0142(19991001)86:7<1129: AID-CNCR5>3.0.CO;2-4 10506695
    • 5-fluorouracil-induced small bowel toxicity in patients with colorectal carcinoma. Fata F, Ron IG, Kemeny N, O'Reilly E, Klimstra D, Kelsen DP, Cancer 1999 86 1129 1134 10.1002/(SICI)1097-0142(19991001)86:7<1129::AID-CNCR5>3. 0.CO;2-4 10506695
    • (1999) Cancer , vol.86 , pp. 1129-1134
    • Fata, F.1    Ron, I.G.2    Kemeny, N.3    O'Reilly, E.4    Klimstra, D.5    Kelsen, D.P.6
  • 11
    • 66149145456 scopus 로고    scopus 로고
    • Gut microbiome and intestinal mucositis: A new challenge for researchers
    • 10.4161/cbt.8.6.7852 19411862
    • Gut microbiome and intestinal mucositis: a new challenge for researchers. Gibson RJ, Cancer Biol Ther 2009 8 512 513 10.4161/cbt.8.6.7852 19411862
    • (2009) Cancer Biol Ther , vol.8 , pp. 512-513
    • Gibson, R.J.1
  • 13
    • 66449134522 scopus 로고    scopus 로고
    • Gastrointestinal microflora and mucins may play a critical role in the development of 5-Fluorouracil-induced gastrointestinal mucositis
    • 10.3181/0810-RM-301 19176868
    • Gastrointestinal microflora and mucins may play a critical role in the development of 5-Fluorouracil-induced gastrointestinal mucositis. Stringer AM, Gibson RJ, Logan RM, Bowen JM, Yeoh AS, Hamilton J, Keefe DM, Exp Biol Med (Maywood) 2009 234 430 441 10.3181/0810-RM-301 19176868
    • (2009) Exp Biol Med (Maywood) , vol.234 , pp. 430-441
    • Stringer, A.M.1    Gibson, R.J.2    Logan, R.M.3    Bowen, J.M.4    Yeoh, A.S.5    Hamilton, J.6    Keefe, D.M.7
  • 14
    • 77953016546 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae strain UFMG 905 protects against bacterial translocation, preserves gut barrier integrity and stimulates the immune system in a murine intestinal obstruction model
    • 10.1007/s00203-010-0574-8 20437166
    • Saccharomyces cerevisiae strain UFMG 905 protects against bacterial translocation, preserves gut barrier integrity and stimulates the immune system in a murine intestinal obstruction model. Generoso SV, Viana M, Santos R, Martins FS, Machado JA, Arantes RM, Nicoli JR, Correia MI, Cardoso VN, Arch Microbiol 2010 192 477 484 10.1007/s00203-010-0574-8 20437166
    • (2010) Arch Microbiol , vol.192 , pp. 477-484
    • Generoso, S.V.1    Viana, M.2    Santos, R.3    Martins, F.S.4    Machado, J.A.5    Arantes, R.M.6    Nicoli, J.R.7    Correia, M.I.8    Cardoso, V.N.9
  • 15
    • 80052540085 scopus 로고    scopus 로고
    • Protection against increased intestinal permeability and bacterial translocation induced by intestinal obstruction in mice treated with viable and heat-killed Saccharomyces boulardii
    • 10.1007/s00394-010-0134-7 20936479
    • Protection against increased intestinal permeability and bacterial translocation induced by intestinal obstruction in mice treated with viable and heat-killed Saccharomyces boulardii. Generoso SV, Viana ML, Santos RG, Arantes RM, Martins FS, Nicoli JR, Machado JA, Correia MI, Cardoso VN, Eur J Nutr 2011 50 261 269 10.1007/s00394-010-0134-7 20936479
    • (2011) Eur J Nutr , vol.50 , pp. 261-269
    • Generoso, S.V.1    Viana, M.L.2    Santos, R.G.3    Arantes, R.M.4    Martins, F.S.5    Nicoli, J.R.6    Machado, J.A.7    Correia, M.I.8    Cardoso, V.N.9
  • 17
    • 33645455337 scopus 로고    scopus 로고
    • Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease
    • 10.1111/j.1572-0241.2006.00465.x 16635227
    • Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. McFarland LV, Am J Gastroenterol 2006 101 812 822 10.1111/j.1572-0241.2006.00465.x 16635227
    • (2006) Am J Gastroenterol , vol.101 , pp. 812-822
    • McFarland, L.V.1
  • 18
    • 43449128102 scopus 로고    scopus 로고
    • Safety of probiotics: Translocation and infection
    • 10.1111/j.1753-4887.2008.00024.x 18366533
    • Safety of probiotics: translocation and infection. Liong MT, Nutr Rev 2008 66 192 202 10.1111/j.1753-4887.2008.00024.x 18366533
    • (2008) Nutr Rev , vol.66 , pp. 192-202
    • Liong, M.T.1
  • 19
    • 0034836517 scopus 로고    scopus 로고
    • Biotherapeutic agents in the treatment of infectious diarrhea
    • 10.1016/S0889-8553(05)70213-2 11586560
    • Biotherapeutic agents in the treatment of infectious diarrhea. Elmer GW, McFarland LV, Gastroenterol Clin North Am 2001 30 837 854 10.1016/S0889-8553(05) 70213-2 11586560
    • (2001) Gastroenterol Clin North Am , vol.30 , pp. 837-854
    • Elmer, G.W.1    McFarland, L.V.2
  • 20
    • 0037042674 scopus 로고    scopus 로고
    • Probiotics in prevention of antibiotic associated diarrhoea: Meta-analysis
    • 10.1136/bmj.324.7350.1361 12052801
    • Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis. D'Souza AL, Rajkumar C, Cooke J, Bulpitt CJ, BMJ 2002 324 1361 10.1136/bmj.324.7350.1361 12052801
    • (2002) BMJ , vol.324 , pp. 1361
    • D'Souza, A.L.1    Rajkumar, C.2    Cooke, J.3    Bulpitt, C.J.4
  • 21
    • 0036286070 scopus 로고    scopus 로고
    • Experimental effects of Saccharomyces boulardii on diarrheal pathogens
    • 10.1016/S1286-4579(02)01592-7 12067833
    • Experimental effects of Saccharomyces boulardii on diarrheal pathogens. Czerucka D, Rampal P, Microbes Infect 2002 4 733 739 10.1016/S1286-4579(02) 01592-7 12067833
    • (2002) Microbes Infect , vol.4 , pp. 733-739
    • Czerucka, D.1    Rampal, P.2
  • 22
    • 33748129610 scopus 로고    scopus 로고
    • Effects of Saccharomyces boulardii on intestinal mucosa
    • 10.1007/s10620-005-9016-x 16838119
    • Effects of Saccharomyces boulardii on intestinal mucosa. Buts JP, De Keyser N, Dig Dis Sci 2006 51 1485 1492 10.1007/s10620-005-9016-x 16838119
    • (2006) Dig Dis Sci , vol.51 , pp. 1485-1492
    • Buts, J.P.1    De Keyser, N.2
  • 23
    • 79953331208 scopus 로고    scopus 로고
    • Probiotic factors partially improve parameters of 5-fluorouracil-induced intestinal mucositis in rats
    • 10.4161/cbt.11.7.14896 21307648
    • Probiotic factors partially improve parameters of 5-fluorouracil-induced intestinal mucositis in rats. Prisciandaro LD, Geier MS, Butler RN, Cummins AG, Howarth GS, Cancer Biol Ther 2011 11 671 677 10.4161/cbt.11.7.14896 21307648
    • (2011) Cancer Biol Ther , vol.11 , pp. 671-677
    • Prisciandaro, L.D.1    Geier, M.S.2    Butler, R.N.3    Cummins, A.G.4    Howarth, G.S.5
  • 24
    • 79960417569 scopus 로고    scopus 로고
    • Oral ingestion of Streptococcus thermophilus does not affect mucositis severity or tumor progression in the tumor-bearing rat
    • 10.4161/cbt.12.2.15720 21508671
    • Oral ingestion of Streptococcus thermophilus does not affect mucositis severity or tumor progression in the tumor-bearing rat. Tooley KL, Howarth GS, Lymn KA, Lawrence A, Butler RN, Cancer Biol Ther 2011 12 131 138 10.4161/cbt.12.2.15720 21508671
    • (2011) Cancer Biol Ther , vol.12 , pp. 131-138
    • Tooley, K.L.1    Howarth, G.S.2    Lymn, K.A.3    Lawrence, A.4    Butler, R.N.5
  • 26
    • 2642522930 scopus 로고    scopus 로고
    • Biochemical and Molecular Studies of Human Methenyltetrahydrofolate Synthetase
    • 10387998
    • Biochemical and Molecular Studies of Human Methenyltetrahydrofolate Synthetase. Jolivet J, Dayan A, Beauchemin M, Chahla D, Mamo A, Bertrand R, Oncologist 1996 1 248 254 10387998
    • (1996) Oncologist , vol.1 , pp. 248-254
    • Jolivet, J.1    Dayan, A.2    Beauchemin, M.3    Chahla, D.4    Mamo, A.5    Bertrand, R.6
  • 27
    • 0038387494 scopus 로고    scopus 로고
    • 5-fluorouracil: Mechanisms of action and clinical strategies
    • 10.1038/nrc1074 12724731
    • 5-fluorouracil: mechanisms of action and clinical strategies. Longley DB, Harkin DP, Johnston PG, Nat Rev Cancer 2003 3 330 338 10.1038/nrc1074 12724731
    • (2003) Nat Rev Cancer , vol.3 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 28
    • 0037838584 scopus 로고    scopus 로고
    • The interaction of thymidylate synthase expression with p53-regulated signaling pathways in tumor cells
    • The interaction of thymidylate synthase expression with p53-regulated signaling pathways in tumor cells. Longley DB, Latif T, Boyer J, Allen WL, Maxwell PJ, Johnston PG, Semin Oncol 2003 30 3 9
    • (2003) Semin Oncol , vol.30 , pp. 3-9
    • Longley, D.B.1    Latif, T.2    Boyer, J.3    Allen, W.L.4    Maxwell, P.J.5    Johnston, P.G.6
  • 29
    • 0036562520 scopus 로고    scopus 로고
    • Oral complications of cancer therapy
    • discussion 686, 691-682, 695 12108892
    • Oral complications of cancer therapy. Sonis ST, Fey EG, Oncology (Williston Park) 2002 16 680 686 discussion 686, 691-682, 695 12108892
    • (2002) Oncology (Williston Park) , vol.16 , pp. 680-686
    • Sonis, S.T.1    Fey, E.G.2
  • 30
    • 84872848721 scopus 로고    scopus 로고
    • Role of endogenous microbiota, probiotics and their biological products in human health
    • 10.3390/nu5010058 23306189
    • Role of endogenous microbiota, probiotics and their biological products in human health. Howarth GS, Wang H, Nutrients 2013 5 58 81 10.3390/nu5010058 23306189
    • (2013) Nutrients , vol.5 , pp. 58-81
    • Howarth, G.S.1    Wang, H.2
  • 31
    • 84879601973 scopus 로고    scopus 로고
    • Molecular mechanisms of platelet and stem cell rebound after 5-fluorouracil treatment
    • Molecular mechanisms of platelet and stem cell rebound after 5-fluorouracil treatment. Li X, Slayton WB, Exp Hematol 2013 7 635 645,e3
    • (2013) Exp Hematol , vol.7 , pp. 635-645
    • Li, X.1    Slayton, W.B.2
  • 32
    • 77956261160 scopus 로고    scopus 로고
    • Glutamine supplementation decreases intestinal permeability and preserves gut mucosa integrity in an experimental mouse model
    • 10.1177/0148607110362530 20631386
    • Glutamine supplementation decreases intestinal permeability and preserves gut mucosa integrity in an experimental mouse model. dos Santos R, Viana ML, Generoso SV, Arantes RE, Davisson Correia MI, Cardoso VN, JPEN J Parenter Enteral Nutr 2010 34 408 413 10.1177/0148607110362530 20631386
    • (2010) JPEN J Parenter Enteral Nutr , vol.34 , pp. 408-413
    • Dos Santos, R.1    Viana, M.L.2    Generoso, S.V.3    Arantes, R.E.4    Davisson Correia, M.I.5    Cardoso, V.N.6
  • 34
    • 0031659166 scopus 로고    scopus 로고
    • Role of intestinal permeability in monitoring mucosal barrier function. History, methodology, and significance of pathophysiology
    • 10.1159/000018651 9845620
    • Role of intestinal permeability in monitoring mucosal barrier function. History, methodology, and significance of pathophysiology. Sun Z, Wang X, Andersson R, Dig Surg 1998 15 386 397 10.1159/000018651 9845620
    • (1998) Dig Surg , vol.15 , pp. 386-397
    • Sun, Z.1    Wang, X.2    Andersson, R.3
  • 35
    • 33847229128 scopus 로고    scopus 로고
    • Probiotic effects on 5-fluorouracil-induced mucositis assessed by the sucrose breath test in rats
    • 10.1007/s10620-006-9464-y 17237997
    • Probiotic effects on 5-fluorouracil-induced mucositis assessed by the sucrose breath test in rats. Mauger CA, Butler RN, Geier MS, Tooley KL, Howarth GS, Dig Dis Sci 2007 52 612 619 10.1007/s10620-006-9464-y 17237997
    • (2007) Dig Dis Sci , vol.52 , pp. 612-619
    • Mauger, C.A.1    Butler, R.N.2    Geier, M.S.3    Tooley, K.L.4    Howarth, G.S.5
  • 36
    • 0035077712 scopus 로고    scopus 로고
    • Saccharomyces boulardii stimulates intestinal immunoglobulin A immune response to Clostridium difficile toxin A in mice
    • 10.1128/IAI.69.4.2762-2765.2001 11254650
    • Saccharomyces boulardii stimulates intestinal immunoglobulin A immune response to Clostridium difficile toxin A in mice. Qamar A, Aboudola S, Warny M, Michetti P, Pothoulakis C, LaMont JT, Kelly CP, Infect Immun 2001 69 2762 2765 10.1128/IAI.69.4.2762-2765.2001 11254650
    • (2001) Infect Immun , vol.69 , pp. 2762-2765
    • Qamar, A.1    Aboudola, S.2    Warny, M.3    Michetti, P.4    Pothoulakis, C.5    Lamont, J.T.6    Kelly, C.P.7
  • 37
    • 49649106937 scopus 로고    scopus 로고
    • Role of hematopoietic microenvironment in prolonged impairment of B cell regeneration in age-related stromal-cell-impaired SAMP1 mouse: Effects of a single dose of 5-fluorouracil
    • 10.1002/jat.1341 18344199
    • Role of hematopoietic microenvironment in prolonged impairment of B cell regeneration in age-related stromal-cell-impaired SAMP1 mouse: effects of a single dose of 5-fluorouracil. Tsuboi I, Hirabayashi Y, Harada T, Koshinaga M, Kawamata T, Kanno J, Inoue T, Aizawa S, J Appl Toxicol 2008 28 797 805 10.1002/jat.1341 18344199
    • (2008) J Appl Toxicol , vol.28 , pp. 797-805
    • Tsuboi, I.1    Hirabayashi, Y.2    Harada, T.3    Koshinaga, M.4    Kawamata, T.5    Kanno, J.6    Inoue, T.7    Aizawa, S.8
  • 38
    • 0023002870 scopus 로고
    • Effects of 5-fluorouracil on B lymphocyte lineage cells
    • 3093575
    • Effects of 5-fluorouracil on B lymphocyte lineage cells. Vetvicka V, Kincade PW, Witte PL, J Immunol 1986 137 2405 2410 3093575
    • (1986) J Immunol , vol.137 , pp. 2405-2410
    • Vetvicka, V.1    Kincade, P.W.2    Witte, P.L.3
  • 39
    • 82455175811 scopus 로고    scopus 로고
    • Anti-inflammatory effects of Saccharomyces boulardii mediated by myeloid dendritic cells from patients with Crohn's disease and ulcerative colitis
    • 10.1152/ajpgi.00217.2011 21903765
    • Anti-inflammatory effects of Saccharomyces boulardii mediated by myeloid dendritic cells from patients with Crohn's disease and ulcerative colitis. Thomas S, Metzke D, Schmitz J, Dorffel Y, Baumgart DC, Am J Physiol Gastrointest Liver Physiol 2011 301 1083 1092 10.1152/ajpgi.00217.2011 21903765
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.301 , pp. 71083-71092
    • Thomas, S.1    Metzke, D.2    Schmitz, J.3    Dorffel, Y.4    Baumgart, D.C.5
  • 40
    • 84876096064 scopus 로고    scopus 로고
    • Inhibition of tissue inflammation and bacterial translocation as one of the protective mechanisms of Saccharomyces boulardii against Salmonella infection in mice
    • 10.1016/j.micinf.2012.12.007 23376166
    • Inhibition of tissue inflammation and bacterial translocation as one of the protective mechanisms of Saccharomyces boulardii against Salmonella infection in mice. Martins FS, Vieira AT, Elian SD, Arantes RM, Tiago FC, Sousa LP, Araujo HR, Pimenta PF, Bonjardim CA, Nicoli JR, Teixeira MM, Microbes Infect 2013 15 270 279 10.1016/j.micinf.2012.12.007 23376166
    • (2013) Microbes Infect , vol.15 , pp. 270-279
    • Martins, F.S.1    Vieira, A.T.2    Elian, S.D.3    Arantes, R.M.4    Tiago, F.C.5    Sousa, L.P.6    Araujo, H.R.7    Pimenta, P.F.8    Bonjardim, C.A.9    Nicoli, J.R.10    Teixeira, M.M.11
  • 41
    • 61849185743 scopus 로고    scopus 로고
    • Saccharomyces boulardii inhibits lipopolysaccharide-induced activation of human dendritic cells and T cell proliferation
    • 10.1111/j.1365-2249.2009.03878.x 19161443
    • Saccharomyces boulardii inhibits lipopolysaccharide-induced activation of human dendritic cells and T cell proliferation. Thomas S, Przesdzing I, Metzke D, Schmitz J, Radbruch A, Baumgart DC, Clin Exp Immunol 2009 156 78 87 10.1111/j.1365-2249.2009.03878.x 19161443
    • (2009) Clin Exp Immunol , vol.156 , pp. 78-87
    • Thomas, S.1    Przesdzing, I.2    Metzke, D.3    Schmitz, J.4    Radbruch, A.5    Baumgart, D.C.6
  • 42
    • 77952653193 scopus 로고    scopus 로고
    • The effect of Saccharomyces boulardii on reducing irinotecan-induced intestinal mucositis and diarrhea
    • 10.1007/s12032-008-9128-1 19067257
    • The effect of Saccharomyces boulardii on reducing irinotecan-induced intestinal mucositis and diarrhea. Sezer A, Usta U, Cicin I, Med Oncol 2009 26 350 357 10.1007/s12032-008-9128-1 19067257
    • (2009) Med Oncol , vol.26 , pp. 350-357
    • Sezer, A.1    Usta, U.2    Cicin, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.