Quantification of pancreatic cancer proteome and phosphorylome: Indicates molecular events likely contributing to cancer and activity of drug targets

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Britton, David ^a   Zen, Yoh ^b   Quaglia, Alberto ^b   Selzer, Stefan ^a   Mitra, Vikram ^a   Löbner, Christopher ^a   Jung, Stephan ^a   Böhm, Gitte ^a   Schmid, Peter ^a   Prefot, Petra ^a   Hoehle, Claudia ^a   Koncarevic, Sasa ^a   Gee, Julia ^d   Nicholson, Robert ^d   Ward, Malcolm ^a   Castellano, Leandro ^c   Stebbing, Justin ^c   Zucht, Hans Dieter ^a   Sarker, Debashis ^b   Heaton, Nigel ^b   Pike, Ian ^a   more..

^a Proteome Sciences plc   (United Kingdom)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE 1; HOMEODOMAIN INTERACTING PROTEIN KINASE 1; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MYOSIN LIGHT CHAIN KINASE; PHOSPHOPEPTIDE; PHOSPHOPROTEIN; PHOSPHORYLOME; PROTEIN AKT1; PROTEIN KINASE B; PROTEIN KINASE FYN; PROTEIN SERINE THREONINE KINASE; PROTEOME; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; SERINE THREONINE PROTEIN KINASE MRCK ALPHA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER; PROTEIN KINASE; TUMOR PROTEIN;

ARTICLE; CANCER TISSUE; CELL MIGRATION; DRUG TARGETING; FOCAL ADHESION; HUMAN; HUMAN TISSUE; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; MASS SPECTROMETRY; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; AMINO ACID SEQUENCE; DISCRIMINANT ANALYSIS; DNA DAMAGE; DNA REPAIR; EXTRACELLULAR MATRIX; GENE ONTOLOGY; METABOLISM; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PSEUDOPODIUM; REGRESSION ANALYSIS;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BIOMARKERS; DISCRIMINANT ANALYSIS; DNA DAMAGE; DNA REPAIR; EXTRACELLULAR MATRIX; FOCAL ADHESIONS; GENE ONTOLOGY; HUMANS; LEAST-SQUARES ANALYSIS; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; PHOSPHOPEPTIDES; PHOSPHORYLATION; PROTEIN KINASES; PROTEOME; PSEUDOPODIA; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84899975734     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090948     Document Type: Article

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