Bio-relevant dissolution testing of hard capsules prepared from different shell materials using the dynamic open flow through test apparatus

European Journal of Pharmaceutical Sciences

Volumn 57, Issue 1, 2014, Pages 264-272

  Garbacz, Grzegorz ^a,b   Cadé, Dominique ^c   Benameur, Hassan ^c   Weitschies, Werner ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b Physiolution GmbH   (Germany)

^c CAPSUGEL   (France)

Author keywords

Biorelevant dissolution testing; Dynamic flow through apparatus; Gastric hydrodynamics; Hard capsules; Hypromellose; Pullulan

Indexed keywords

CAFFEINE; EXCIPIENT; GELATIN; HYDROXYPROPYLMETHYLCELLULOSE; PULLULAN; GLUCAN; MICROCAPSULE;

ARTICLE; DIET RESTRICTION; DRUG CAPSULE; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DYNAMIC OPEN FLOW THROUGH TEST APPARATUS; FLOW RATE; HEAT EXCHANGE; MATERIALS TESTING; PRESSURE; PRIORITY JOURNAL; SIMULATOR; STOMACH MOTILITY; TEMPERATURE DEPENDENCE; CHEMISTRY; DEVICES; EQUIPMENT DESIGN; HARDNESS; HUMAN; KINETICS; MEDICINAL CHEMISTRY; MICROCAPSULE; ORAL DRUG ADMINISTRATION; PH; PHARMACEUTICS; PHYSIOLOGY; PROCEDURES; SOLUBILITY; STOMACH; STOMACH EMPTYING; TEMPERATURE;

ADMINISTRATION, ORAL; BIOPHARMACEUTICS; CAFFEINE; CAPSULES; CHEMISTRY, PHARMACEUTICAL; EQUIPMENT DESIGN; EXCIPIENTS; FASTING; GASTRIC EMPTYING; GELATIN; GLUCANS; HARDNESS; HARDNESS TESTS; HUMANS; HYDROGEN-ION CONCENTRATION; HYPROMELLOSE DERIVATIVES; KINETICS; PRESSURE; SOLUBILITY; STOMACH; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 84899964638     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.08.039     Document Type: Article

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