The neural correlates of regulating positive and negative emotions in medication-free major depression

Social Cognitive and Affective Neuroscience

Volumn 9, Issue 5, 2014, Pages 628-637

  Greening, Steven G ^a,b   Osuch, Elizabeth A ^a,c   Williamson, Peter C ^a,c   Mitchell, Derek G V ^a,b  

^a WESTERN UNIVERSITY   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

Amygdala; Attention; Cognitive control; Depression; Emotion regulation; Prefrontal cortex

Indexed keywords

OXYGEN;

ADOLESCENT; ADULT; BLOOD; BRAIN; BRAIN MAPPING; EMOTION; EXECUTIVE FUNCTION; FEMALE; HUMAN; MAJOR DEPRESSION; MALE; MIDDLE AGED; NERVE TRACT; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHOTOSTIMULATION; PHYSIOLOGY; PREFRONTAL CORTEX; SEVERITY OF ILLNESS INDEX; VASCULARIZATION; VENTRAL STRIATUM; VISION; YOUNG ADULT;

ADOLESCENT; ADULT; BRAIN; BRAIN MAPPING; DEPRESSIVE DISORDER, MAJOR; EMOTIONS; EXECUTIVE FUNCTION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURAL PATHWAYS; NEUROPSYCHOLOGICAL TESTS; OXYGEN; PHOTIC STIMULATION; PREFRONTAL CORTEX; SEVERITY OF ILLNESS INDEX; VENTRAL STRIATUM; VISUAL PERCEPTION; YOUNG ADULT;

EID: 84899962743     PISSN: 17495016     EISSN: 17495024     Source Type: Journal    
DOI: 10.1093/scan/nst027     Document Type: Article

References (76)

1. Beauregard, M., Paquette, V., Levesque, J. (2006). Dysfunction in the neural circuitry of emotional self-regulation in major depressive disorder. Neuroreport, 17, 843-6.
2. Beck, A.T., Rush, A.J., Shaw, B.F., Emery, G. (1979). Cognitive Therapy of Depression. New York: The Guilford Press.
3. Beck, A.T., Steer, R.A., Brown, G.K. (1996). Manual for the Beck Depression Inventory-II. San Antonio, TX: Psychological Corporation.
4. Blair, R.J., Mitchell, D.G. (2009). Psychopathy, attention and emotion. Psychological Medicine, 39, 543-55.
5. Bluhm, R., Williamson, P., Lanius, R., et al. (2009). Resting state default-mode network connectivity in early depression using a seed region-of-interest analysis: decreased connectivity with caudate nucleus. Psychiatry and Clinical Neurosciences, 63, 754-61.
6. Campbell-Sills, L., Barlow, D.H. (2007). Incorporating emotion regulation into comceptualizations of treatments of anxiety and mood disorders. In: Gross, J.J., editor. Handbook of Emotion Regulation. New York: The Guilford Press.
7. Chen, G., Saad, Z.S., Nath, A.R., Beauchamp, M.S., Cox, R.W. (2012). FMRI group analysis combining effect estimates and their variances. Neuroimage, 60, 747-65.
8. Clark, D.A., Beck, A.T. (2010). Cognitive theory and therapy of anxiety and depression: convergence with neurobiological findings. Trends in Cognitive Sciences, 14, 418-24.
9. Cox, R.W. (1996). AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Computers and Biomedical Research, 29, 162-73.
10. Davidson, R.J., Pizzagalli, D., Nitschke, J.B., Putnam, K. (2002). Depression: perspectives from affective neuroscience. Annual Review of Psychology, 53, 545-74.
11. de Raedt, R., Koster, E.H., Joormann, J. (2010). Attentional control in depression: a translational affective neuroscience approach. Cognitive, Affective, and Behavioral Neuroscience, 10, 1-7.
12. Delgado, M.R., Nearing, K.I., Ledoux, J.E., Phelps, E.A. (2008). Neural circuitry underlying the regulation of conditioned fear and its relation to extinction. Neuron, 59, 829-38.
13. Devlin, J.T., Russell, R.P., Davis, M.H., et al. (2000). Susceptibility-induced loss of signal: comparing PET and fMRI on a semantic task. Neuroimage, 11, 589-600.
14. Drevets, W.C., Videen, T.O., Price, J.L., Preskorn, S.H., Carmichael, S.T., Raichle, M.E. (1992). A functional anatomical study of unipolar depression. Journal of Neuroscience, 12, 3628-41.
15. Eddington, K.M., Dolcos, F., Mclean, A.N., Krishnan, K.R., Cabeza, R., Strauman, T.J. (2009). Neural correlates of idiographic goal priming in depression: goal-specific dysfunctions in the orbitofrontal cortex. Social Cognitive and Affective Neuroscience, 4, 238-46.
16. Epstein, J., Pan, H., Kocsis, J.H., et al. (2006). Lack of ventral striatal response to positive stimuli in depressed versus normal subjects. American Journal of Psychiatry, 163, 1784-90.
17. Erk, S., Mikschl, A., Stier, S., et al. (2010). Acute and sustained effects of cognitive emotion regulation in major depression. Journal of Neuroscience, 30, 15726-34.
18. Fales, C.L., Barch, D.M., Rundle, M.M., et al. (2008). Altered emotional interference processing in affective and cognitive-control brain circuitry in major depression. Biological Psychiatry, 63, 377-84.
19. Fales, C.L., Barch, D.M., Rundle, M.M., et al. (2009). Antidepressant treatment normalizes hypoactivity in dorsolateral prefrontal cortex during emotional interference processing in major depression. Journal of Affective Disorders, 112, 206-11.
20. Farb, N.A., Anderson, A.K., Mayberg, H., et al. (2010). Minding one's emotions: mindfulness training alters the neural expression of sadness. Emotion, 10, 25-33.
21. First, M.B., Spitzer, R.L., Gibbon, M., Williams, J.B.W. (2002). Structured clinical interview for DSM-IV-TR Axis I disorders, research version, Patient Edition. (SCID-I/P). New York: Biometrics Research, New York State Psychiatric Institute.
22. Goldapple, K., Segal, Z., Garson, C., et al. (2004). Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy. Archives of General Psychiatry, 61, 34-41.
23. Goldin, P.R., Mcrae, K., Ramel, W., Gross, J.J. (2008). The neural bases of emotion regulation: reappraisal and suppression of negative emotion. Biological Psychiatry, 63, 577-86.
24. Green, S., Lambon Ralph, M.A., Moll, J., Deakin, J.F., Zahn, R. (2012). Guilt-selective functional disconnection of anterior temporal and subgenual cortices in major depressive disorder. Archives of General Psychiatry, 1-8.
25. Greening, S.G., Finger, E.C., Mitchell, D.G. (2011). Parsing decision making processes in prefrontal cortex: response inhibition, overcoming learned avoidance, and reversal learning. Neuroimage, 54, 1432-41.
26. Gross, J.J. (1998). Antecedent-and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. Journal of Personality and Social Psychology, 74, 224-37.
27. Han, T., Alders, G.L., Greening, S.G., Neufeld, R.W., Mitchell, D.G. (2011). Do fearful eyes activate empathy-related brain regions in individuals with callous traits? Social Cognitive and Affective Neuroscience, 7, 958-68.
28. Heller, A.S., Johnstone, T., Shackman, A.J., et al. (2009). Reduced capacity to sustain positive emotion in major depression reflects diminished maintenance of fronto-striatal brain activation. Proceedings of the National Academy of Sciences of the United States of America, 106, 22445-50.
29. Ishai, A., Pessoa, L., Bikle, P.C., Ungerleider, L.G. (2004). Repetition suppression of faces is modulated by emotion. Proceedings of the National Academy of Sciences of the United States of America, 101, 9827-32.
30. Jensen, K.B., Berna, C., Loggia, M.L., Wasan, A.D., Edwards, R.R., Gollub, R.L. (2012). The use of functional neuroimaging to evaluate psychological and other non-pharmacological treatments for clinical pain. Neuroscience Letters, 520, 156-64.
31. Johnstone, T., van Reekum, C.M., Urry, H.L., Kalin, N.H., Davidson, R.J. (2007). Failure to regulate: counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depression. Journal of Neuroscience, 27, 8877-84.
32. Kennedy, S.H., Evans, K.R., Kruger, S., et al. (2001). Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression. American Journal of Psychiatry, 158, 899-905.
33. Koenigs, M., Huey, E.D., Calamia, M., Raymont, V., Tranel, D., Grafman, J. (2008). Distinct regions of prefrontal cortex mediate resistance and vulnerability to depression. Journal of Neuroscience, 28, 12341-8.
34. Kringelbach, M.L., Rolls, E.T. (2003). Neural correlates of rapid reversal learning in a simple model of human social interaction. Neuroimage, 20, 1371-83.
35. Kross, E., Davidson, M., Weber, J., Ochsner, K. (2009). Coping with emotions past: the neural bases of regulating affect associated with negative autobiographical memories. Biological Psychiatry, 65, 361-6.
36. Lang, P.J., Bradley, M.M., Cuthbert, B.N. (2008). International Affective Picture System (IAPS): Affective Ratings of Pictures and Instruction Manual. Technical report A-8. Gainesville, FL: University of Florida.
37. Lemogne, C., le Bastard, G., Mayberg, H., et al. (2009). In search of the depressive self: extended medial prefrontal network during self-referential processing in major depression. Social Cognitive and Affective Neuroscience, 4, 305-12.
38. Levens, S.M., Muhtadie, L., Gotlib, I.H. (2009). Rumination and impaired resource allocation in depression. Journal of Abnormal Psychology, 118, 757-66.
39. Light, S.N., Heller, A.S., Johnstone, T., et al. (2011). Reduced right ventrolateral prefrontal cortex activity while inhibiting positive affect is associated with improvement in hedonic capacity after 8 weeks of antidepressant treatment in major depressive disorder. Biological Psychiatry, 70, 962-8.
40. Linden, D.E. (2006). How psychotherapy changes the brain-the contribution of functional neuroimaging. Molecolar Psychiatry, 11, 528-38.
41. Lindquist, K.A., Wager, T.D., Kober, H., Bliss-Moreau, E., Barrett, L.F. (2012). The brain basis of emotion: a meta-analytic review. Behavioral and Brain Science, 35, 121-43.
42. Mayberg, H. (2002). Depression, II: localization of pathophysiology. American Journal of Psychiatry, 159, 1979.
43. Mayberg, H.S., Lozano, A.M., Voon, V., et al. (2005). Deep brain stimulation for treatment-resistant depression. Neuron, 45, 651-60.
44. Mikels, J.A., Fredrickson, B.L., Larkin, G.R., Lindberg, C.M., Maglio, S.J., Reuter-Lorenz, P.A. (2005). Emotional category data on images from the international affective picture system. Behaviour Research Methods, 37, 626-30.
45. Mitchell, D.G. (2011). The nexus between decision making and emotion regulation: a review of convergent neurocognitive substrates. Behavioral Brain Research, 217, 215-31.
46. Mitchell, D.G., Greening, S.G. (2012). Conscious perception of emotional stimuli: brain mechanisms. Neuroscientist, 18, 386-98.
47. Mitchell, D.G., Luo, Q., Avny, S.B., et al. (2009). Adapting to dynamic stimulus-response values: differential contributions of inferior frontal, dorsomedial, and dorsolateral regions of prefrontal cortex to decision making. Journal of Neuroscience, 29, 10827-34.
48. Moll, J., Zahn, R., de Oliveira-Souza, R., Krueger, F., Grafman, J. (2005). Opinion: the neural basis of human moral cognition. Nature Reviews Neuroscience, 6, 799-809.
49. Ochsner, K.N., Bunge, S.A., Gross, J.J., Gabrieli, J.D. (2002). Rethinking feelings: an FMRI study of the cognitive regulation of emotion. Journal of Cognitive Neuroscience, 14, 1215-29.
50. Ochsner, K.N., Gross, J.J. (2005). The cognitive control of emotion. Trends in Cognitive Sciences, 9, 242-9.
51. Ochsner, K.N., Ray, R.D., Cooper, J.C., et al. (2004). For better or for worse: neural systems supporting the cognitive down-and up-regulation of negative emotion. Neuroimage, 23, 483-99.
52. Osuch, E.A., Bluhm, R.L., Williamson, P.C., Theberge, J., Densmore, M., Neufeld, R.W. (2009). Brain activation to favorite music in healthy controls and depressed patients. Neuroreport, 20, 1204-8.
53. Padmala, S., Pessoa, L. (2008). Affective learning enhances visual detection and responses in primary visual cortex. Journal of Neuroscience, 28, 6202-10.
54. Padmala, S., Pessoa, L. (2011). Reward reduces conflict by enhancing attentional control and biasing visual cortical processing. Journal of Cognitive Neuroscience, 23, 3419-32.
55. Pessoa, L., Mckenna, M., Gutierrez, E., Ungerleider, L.G. (2002). Neural processing of emotional faces requires attention. Proceedings of the National Academy of Sciences of the United States of America, 99, 11458-63.
56. Peters, J., Kalivas, P.W., Quirk, G.J. (2009). Extinction circuits for fear and addiction overlap in prefrontal cortex. Learning and Memory, 16, 279-88.
57. Phan, K.L., Fitzgerald, D.A., Nathan, P.J., Moore, G.J., Uhde, T.W., Tancer, M.E. (2005). Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study. Biological Psychiatry, 57, 210-9.
58. Phillips, M.L., Drevets, W.C., Rauch, S.L., Lane, R. (2003). Neurobiology of emotion perception II: Implications for major psychiatric disorders. Biological Psychiatry, 54, 515-28.
59. Pizzagalli, D.A., Holmes, A.J., Dillon, D.G., et al. (2009). Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder. American Journal of Psychiatry, 166, 702-10.
60. Price, J.L., Drevets, W.C. (2010). Neurocircuitry of mood disorders. Neuropsychopharmacology, 35, 192-216.
61. Rajkowska, G., Halaris, A., Selemon, L.D. (2001). Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biological Psychiatry, 49, 741-52.
62. Rajkowska, G., Miguel-Hidalgo, J.J., Wei, J., et al. (1999). Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biological Psychiatry, 45, 1085-98.
63. Ritchey, M., Dolcos, F., Eddington, K.M., Strauman, T.J., Cabeza, R. (2011). Neural correlates of emotional processing in depression: changes with cognitive behavioral therapy and predictors of treatment response. Journal of Psychiatric Research, 45, 577-87.
64. Robinson, O.J., Cools, R., Carlisi, C.O., Sahakian, B.J., Drevets, W.C. (2012). Ventral striatum response during reward and punishment reversal learning in unmedicated major depressive disorder. American Journal of Psychiatry, 169, 152-9.
65. Rottenberg, J., Kasch, K.L., Gross, J.J., Gotlib, I.H. (2002). Sadness and amusement reactivity differentially predict concurrent and prospective functioning in major depressive disorder. Emotion, 2, 135-46.
66. Segal, Z.V., Kennedy, S., Gemar, M., Hood, K., Pedersen, R., Buis, T. (2006). Cognitive reactivity to sad mood provocation and the prediction of depressive relapse. Archives of General Psychiatry, 63, 749-55.
67. Siegle, G.J., Thompson, W., Carter, C.S., Steinhauer, S.R., Thase, M.E. (2007). Increased amygdala and decreased dorsolateral prefrontal BOLD responses in unipolar depression: related and independent features. Biological Psychiatry, 61, 198-209.
68. Suslow, T., Konrad, C., Kugel, H., et al. (2010). Automatic mood-congruent amygdala responses to masked facial expressions in major depression. Biological Psychiatry, 67, 155-60.
69. Urry, H.L., van Reekum, C.M., Johnstone, T., et al. (2006). Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults. Journal of Neuroscience, 26, 4415-25.
70. Veltman, D.J., Friston, K.J., Sanders, G., Price, C.J. (2000). Regionally specific sensitivity differences in fMRI and PET: where do they come from? Neuroimage, 11, 575-88.
71. Victor, T.A., Furey, M.L., Fromm, S.J., Ohman, A., Drevets, W.C. (2010). Relationship between amygdala responses to masked faces and mood state and treatment in major depressive disorder. Archives of General Psychiatry, 67, 1128-38.
72. Vuilleumier, P., Armony, J.L., Driver, J., Dolan, R.J. (2001). Effects of attention and emotion on face processing in the human brain: an event-related fMRI study. Neuron, 30, 829-41.
73. Wager, T.D., Davidson, M.L., Hughes, B.L., Lindquist, M.A., Ochsner, K.N. (2008). Prefrontal-subcortical pathways mediating successful emotion regulation. Neuron, 59, 1037-50.
74. Wood, J.N., Grafman, J. (2003). Human prefrontal cortex: processing and representational perspectives. Nature Reviews Neuroscience, 4, 139-47.
75. World Health Organization. (2003). Investing in Mental Health. Geneva, Switzerland: Department of Mental Health and Substance Dependence.
76. Yarkoni, T. (2009). Big correlations in little studies: inflated fMRI correlations refelct low statistical power. Perspectives on Psychological Science, 4, 294-8.