Prefrontal-Subcortical Pathways Mediating Successful Emotion Regulation

Neuron

Volumn 59, Issue 6, 2008, Pages 1037-1050

  Wager, Tor D ^a   Davidson, Matthew L ^a   Hughes, Brent L ^a   Lindquist, Martin A ^a   Ochsner, Kevin N ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

SYSNEURO

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; BASAL GANGLION; BRAIN CORTEX; BRAIN FUNCTION; BRAIN REGION; CONTROLLED STUDY; EMOTION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; SELF REPORT; THALAMUS VENTRAL NUCLEUS;

ADAPTATION, PSYCHOLOGICAL; ADULT; AMYGDALA; BRAIN MAPPING; COMPREHENSION; CONCEPT FORMATION; EMOTIONS; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEURAL PATHWAYS; PREFRONTAL CORTEX;

EID: 52049106624     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2008.09.006     Document Type: Article

References (73)

1. Abercrombie H.C., Schaefer S.M., Larson C.L., Oakes T.R., Lindgren K.A., Holden J.E., Perlman S.B., Turski P.A., Krahn D.D., Benca R.M., and Davidson R.J. Metabolic rate in the right amygdala predicts negative affect in depressed patients. Neuroreport 9 (1998) 3301-3307
2. Aron A.R., and Poldrack R.A. The cognitive neuroscience of response inhibition: relevance for genetic research in attention-deficit/hyperactivity disorder. Biol. Psychiatry 57 (2005) 1285-1292
3. Badre D., and Wagner A.D. Frontal lobe mechanisms that resolve proactive interference. Cereb. Cortex 15 (2005) 2003-2012
4. Baron R.M., and Kenny D.A. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J. Pers. Soc. Psychol. 51 (1986) 1173-1182
5. Barrett L.F., Mesquita B., Ochsner K.N., and Gross J.J. The Experience of Emotion. Annu. Rev. Psychol. 58 (2007) 373-403
6. Beauregard M., Levesque J., and Bourgouin P. Neural correlates of conscious self-regulation of emotion. J. Neurosci. 21 (2001) RC165
7. Breiter H.C., Aharon I., Kahneman D., Dale A., and Shizgal P. Functional imaging of neural responses to expectancy and experience of monetary gains and losses. Neuron 30 (2001) 619-639
8. Brody A.L., Saxena S., Silverman D.H.S., Alborzian S., Fairbanks L.A., Phelps M.E., Huang S.C., Wu H.M., Maidment K., and Baxter L.R. Brain metabolic changes in major depressive disorder from pre-to post-treatment with paroxetine. Psychiatry Res. 91 (1999) 127-139
9. Brody A.L., Saxena S., Stoessel P., Gillies L.A., Fairbanks L.A., Alborzian S., Phelps M.E., Huang S.C., Wu H.M., and Ho M.L. Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: preliminary findings. Arch. Gen. Psychiatry 58 (2001) 631-640
10. Cole M.W., and Schneider W. The cognitive control network: Integrated cortical regions with dissociable functions. Neuroimage 37 (2007) 343-360
11. Cromwell H.C., and Schultz W. Effects of expectations for different reward magnitudes on neuronal activity in primate striatum. J. Neurophysiol. 89 (2003) 2823-2838
12. Cunningham W.A., and Zelazo P.D. Attitudes and evaluations: a social cognitive neuroscience perspective. Trends Cogn. Sci. 11 (2007) 97-104
13. Davidson R.J. Anxiety and affective style: role of prefrontal cortex and amygdala. Biol. Psychiatry 51 (2002) 68-80
14. Davidson R.J., Putnam K.M., and Larson C.L. Dysfunction in the neural circuitry of emotion regulation--a possible prelude to violence. Science 289 (2000) 591-594
15. Davis M. The role of the amygdala in fear and anxiety. Annu. Rev. Neurosci. 15 (1992) 353-375
16. Drevets W.C., Videen T.O., Price J.L., Preskorn S.H., Carmichael S.T., and Raichle M.E. A functional anatomical study of unipolar depression. J. Neurosci. 12 (1992) 3628-3641
17. Efron B., and Tibshirani R. An Introduction to the Bootstrap (1993), Chapman & Hall/CRC, New York
18. Eippert F., Veit R., Weiskopf N., Erb M., Birbaumer N., and Anders S. Regulation of emotional responses elicited by threat-related stimuli. Hum. Brain Mapp. 28 (2007) 409-423
19. Etkin A., and Wager T.D. Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Am. J. Psychiatry 164 (2007) 1476-1488
20. Genovese C.R., Lazar N.A., and Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 15 (2002) 870-878
21. Goldapple K., Segal Z., Garson C., Lau M., Bieling P., Kennedy S., and Mayberg H. Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy. Arch. Gen. Psychiatry 61 (2004) 34-41
22. Goldin P.R., McRae K., Ramel W., and Gross J.J. The neural bases of emotion regulation: reappraisal and suppression of negative emotion. Biol. Psychiatry 63 (2007) 577-586
23. Gross J.J., and Munoz R.F. Emotion regulation and mental health. Clin. Psychol. Sci. Pract. 2 (1995) 151-164
24. Holland P.C., and Gallagher M. Amygdala circuitry in attentional and representational processes. Trends Cogn. Sci. 3 (1999) 65-73
25. Hyman H.H. Survey Design and Analysis: Principles, Cases, and Procedures (1955), Free Press, Glencoe, IL
26. Jensen J., McIntosh A.R., Crawley A.P., Mikulis D.J., Remington G., and Kapur S. Direct activation of the ventral striatum in anticipation of aversive stimuli. Neuron 40 (2003) 1251-1257
27. Johnstone T., van Reekum C.M., Urry H.L., Kalin N.H., and Davidson R.J. Failure to regulate: counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depression. J. Neurosci. 27 (2007) 8877-8884
28. Kalisch R., Wiech K., Critchley H.D., Seymour B., O'Doherty J.P., Oakley D.A., Allen P., and Dolan R.J. Anxiety reduction through detachment: subjective, physiological, and neural effects. J. Cogn. Neurosci. 17 (2005) 874-883
29. Kalisch R., Wiech K., Herrmann K., and Dolan R.J. Neural correlates of self-distraction from anxiety and a process model of cognitive emotion regulation. J. Cogn. Neurosci. 18 (2006) 1266-1276
30. Kim S.H., and Hamann S. Neural correlates of positive and negative emotion regulation. J. Cogn. Neurosci. 19 (2007) 776-798
31. Kober H., Barrett L.F., Joseph J., Bliss-Moreau E., Lindquist K., and Wager T.D. Functional grouping and cortical-subcortical interactions in emotion: A meta-analysis of neuroimaging studies. Neuroimage 42 (2008) 998-1031
32. Lang P.J., Greenwald M.K., Bradley M.M., and Hamm A.O. Looking at pictures: affective, facial, visceral, and behavioral reactions. Psychophysiology 30 (1993) 261-273
33. Lawrence N.S., Williams A.M., Surguladze S., Giampietro V., Brammer M.J., Andrew C., Frangou S., Ecker C., and Phillips M.L. Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression. Biol. Psychiatry 55 (2004) 578-587
34. Lazarus R.S. Cognition and motivation in emotion. Am. Psychol. 46 (1991) 352-367
35. Levita L., Dalley J.W., and Robbins T.W. Nucleus accumbens dopamine and learned fear revisited: a review and some new findings. Behav. Brain Res. 137 (2002) 115-127
36. Lieberman M.D., Eisenberger N.I., Crockett M.J., Tom S.M., Pfeifer J.H., and Way B.M. Putting feelings into words: affect labeling disrupts amygdala activity in response to affective stimuli. Psychol. Sci. 18 (2007) 421-428
37. MacCorquodale K., and Meehl P.E. On a distinction between hypothetical constructs and intervening variables. Psychol. Rev. 55 (1948) 307-321
38. MacKinnon D.P., Krull J.L., and Lockwood C.M. Equivalence of the mediation, confounding and suppression effect. Prev. Sci. 1 (2000) 173-181
39. McClure S.M., Berns G.S., and Montague P.R. Temporal prediction errors in a passive learning task activate human striatum. Neuron 38 (2003) 339-346
40. McRae K., Ochsner K.N., Mauss I.B., Gabrieli J.J.D., and Gross J.J. Gender differences in emotion regulation: An fMRI study of cognitive reappraisal. Group Processes and Intergroup Relations 11 (2008) 143
41. McRae K., Reiman E.M., Fort C.L., Chen K., and Lane R.D. Association between trait emotional awareness and dorsal anterior cingulate activity during emotion is arousal-dependent. Neuroimage 41 (2008) 648-655
42. Metcalfe J., and Mischel W. A hot/cool-system analysis of delay of gratification: dynamics of willpower. Psychol. Rev. 106 (1999) 3-19
43. Milad M.R., and Quirk G.J. Neurons in medial prefrontal cortex signal memory for fear extinction. Nature 420 (2002) 70-74
44. Moskowitz J.T. Positive affect predicts lower risk of AIDS mortality. Psychosom. Med. 65 (2003) 620-626
45. Munafo M.R., Brown S.M., and Hariri A.R. Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis. Biol. Psychiatry 63 (2008) 852-857
46. Nee D.E., Wager T.D., and Jonides J. A meta-analysis of neuroimaging studies of interference resolution. Cogn. Affect. Behav. Neurosci. 7 (2007) 1-17
47. Ochsner K.N., and Barrett L.F. A multiprocess perspective on the neuroscience of emotion. In: Mayne T.J., and Bonanno G.A. (Eds). Emotions: Currrent issues and future directions (2001), The Guilford Press, New York, NY 38-81
48. Ochsner K.N., and Gross J.J. The cognitive control of emotion. Trends Cogn. Sci. 9 (2005) 242-249
49. Ochsner K.N., and Gross J.J. Cognitive emotion regulation: Insights from social cognitive and affective neuroscience. Curr. Dir. Psychol. Sci. 17 (2008) 153-158
50. Ochsner K.N., Bunge S.A., Gross J.J., and Gabrieli J.D. Rethinking feelings: an FMRI study of the cognitive regulation of emotion. J. Cogn. Neurosci. 14 (2002) 1215-1229
51. Ochsner K.N., Ray R.D., Cooper J.C., Robertson E.R., Chopra S., Gabrieli J.D., and Gross J.J. For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion. Neuroimage 23 (2004) 483-499
52. Ohira H., Nomura M., Ichikawa N., Isowa T., Iidaka T., Sato A., Fukuyama S., Nakajima T., and Yamada J. Association of neural and physiological responses during voluntary emotion suppression. Neuroimage 29 (2006) 721-733
53. Ollinger J.M., Corbetta M., and Shulman G.L. Separating processes within a trial in event-related functional MRI. Neuroimage 13 (2001) 218-229
54. Paton J.J., Belova M.A., Morrison S.E., and Salzman C.D. The primate amygdala represents the positive and negative value of visual stimuli during learning. Nature 439 (2006) 865-870
55. Phan K.L., Fitzgerald D.A., Nathan P.J., Moore G.J., Uhde T.W., and Tancer M.E. Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study. Biol. Psychiatry 57 (2005) 210-219
56. Phelps E.A. Emotion and cognition: insights from studies of the human amygdala. Annu. Rev. Psychol. 57 (2006) 27-53
57. Phillips M.L., Drevets W.C., Rauch S.L., and Lane R. Neurobiology of emotion perception II: Implications for major psychiatric disorders. Biol. Psychiatry 54 (2003) 515-528
58. Pitkanen A. Connectivity of the rat amygdaloid complex. In: Aggleton J.P. (Ed). The amygdala: a functional analysis (2000), Oxford University Press, New York 31-116
59. Schaefer S.M., Jackson D.C., Davidson R.J., Aguirre G.K., Kimberg D.Y., and Thompson-Schill S.L. Modulation of amygdalar activity by the conscious regulation of negative emotion. J. Cogn. Neurosci. 14 (2002) 913-921
60. Scherer K.R. Appraisal considered as a process of multilevel sequential checking. In: Scherer K.R., Schorr A., and Johnstone T. (Eds). Appraisal Processes in Emotion: Theory, Methods, Research (2001), Oxford University Press, New York 92-120
61. Schmitz T.W., and Johnson S.C. Relevance to self: A brief review and framework of neural systems underlying appraisal. Neurosci. Biobehav. Rev. 31 (2007) 585-596
62. Schultz W. Neural coding of basic reward terms of animal learning theory, game theory, microeconomics and behavioural ecology. Curr. Opin. Neurobiol. 14 (2004) 139-147
63. Scott D.J., Stohler C.S., Egnatuk C.M., Wang H., Koeppe R.A., and Zubieta J.K. Individual differences in reward responding explain placebo-induced expectations and effects. Neuron 55 (2007) 325-336
64. Shrout P.E., and Bolger N. Mediation in experimental and nonexperimental studies: new procedures and recommendations. Psychol. Methods 7 (2002) 422-445
65. Stern E.R., Wager T.D., Egner T., Hirsch J., and Mangels J.A. Preparatory neural activity predicts performance on a conflict task. Brain Res. 1176 (2007) 92-102
66. Tindell A.J., Smith K.S., Pecina S., Berridge K.C., and Aldridge J.W. Ventral pallidum firing codes hedonic reward: when a bad taste turns good. J. Neurophysiol. 96 (2006) 2399-2409
67. Tugade M.M., Fredrickson B.L., and Feldman Barrett L. Psychological resilience and positive emotional granularity: examining the benefits of positive emotions on coping and health. J. Pers. 72 (2004) 1161-1190
68. Urry H.L., van Reekum C.M., Johnstone T., Kalin N.H., Thurow M.E., Schaefer H.S., Jackson C.A., Frye C.J., Greischar L.L., Alexander A.L., and Davidson R.J. Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults. J. Neurosci. 26 (2006) 4415-4425
69. van Reekum C.M., Johnstone T., Urry H.L., Thurow M.E., Schaefer H.S., Alexander A.L., and Davidson R.J. Gaze fixations predict brain activation during the voluntary regulation of picture-induced negative affect. Neuroimage 36 (2007) 1041-1055
70. Wager T.D., Keller M.C., Lacey S.C., and Jonides J. Increased sensitivity in neuroimaging analyses using robust regression. Neuroimage 26 (2005) 99-113
71. Wager T.D., Scott D.J., and Zubieta J.K. Placebo effects on human mu-opioid activity during pain. Proc. Natl. Acad. Sci. USA 104 (2007) 11056-11061
72. Wager T.D., Barrett L.F., Bliss-Moreau E., Lindquist K., Duncan S., Kober H., Joseph J., Davidson M., and Mize J. The neuroimaging of emotion. In: Lewis M., Haviland-Jones J.M., and Barrett L.F. (Eds). Handbook of Emotion (2008), Guilford Press, New York 249-271
73. Whalen P.J. Fear, vigilance, and ambiguity: Initial neuroimaging studies of the human amygdala. Curr. Dir. Psychol. Sci. 7 (1998) 177-188