메뉴 건너뛰기




Volumn 85, Issue 5, 2014, Pages 1225-1237

Subfractionation, characterization, and in-depth proteomic analysis of glomerular membrane vesicles in human urine

Author keywords

Actin cytoskeleton; Exosome; Glomerular disease; Podocyte; Proteomics; Q exactive mass spectrometer

Indexed keywords

ALBUMIN; COMPLEMENT; INTEGRIN; NEPHRIN; PHOSPHOLIPASE A2 RECEPTOR; PODOCALYXIN; PODOCIN; PROTEINASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; BIOLOGICAL MARKER;

EID: 84899954902     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.422     Document Type: Article
Times cited : (99)

References (96)
  • 1
    • 33751199883 scopus 로고    scopus 로고
    • Exosomes: From biogenesis and secretion to biological function
    • Keller S, Sanderson MP, Stoeck A et al. Exosomes: from biogenesis and secretion to biological function. Immunol Lett 2006; 107: 102-108.
    • (2006) Immunol Lett , vol.107 , pp. 102-108
    • Keller, S.1    Sanderson, M.P.2    Stoeck, A.3
  • 3
    • 18844395894 scopus 로고    scopus 로고
    • Revisiting the road to the discovery of exosomes
    • Johnstone RM. Revisiting the road to the discovery of exosomes. Blood Cells Molecules Diseases 2005; 34: 214-219.
    • (2005) Blood Cells Molecules Diseases , vol.34 , pp. 214-219
    • Johnstone, R.M.1
  • 4
    • 4444226979 scopus 로고    scopus 로고
    • Identification and proteomic profiling of exosomes in human urine
    • Pisitkun T, Shen RF, Knepper MA. Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci USA 2004; 101: 13368-13373.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13368-13373
    • Pisitkun, T.1    Shen, R.F.2    Knepper, M.A.3
  • 6
    • 35348938217 scopus 로고    scopus 로고
    • Exosomes in urine: Who would have thought
    • Knepper MA, Pisitkun T. Exosomes in urine: who would have thought.? Kidney Int 2007; 72: 1043-1045.
    • (2007) Kidney Int , vol.72 , pp. 1043-1045
    • Knepper, M.A.1    Pisitkun, T.2
  • 7
    • 0009732556 scopus 로고
    • An electron microscope examination of urinary mucoprotein and its interaction with influenza virus
    • Bayer ME. An electron microscope examination of urinary mucoprotein and its interaction with influenza virus. J Cell Biol 1964; 21: 265-274.
    • (1964) J Cell Biol , vol.21 , pp. 265-274
    • Bayer, M.E.1
  • 9
    • 84857719292 scopus 로고    scopus 로고
    • Uromodulin exclusion list improves urinary exosomal protein identification
    • Hiemstra TF, Charles PD, Hester SS et al. Uromodulin exclusion list improves urinary exosomal protein identification. J Biomol Tech 2011; 22: 136-145.
    • (2011) J Biomol Tech , vol.22 , pp. 136-145
    • Hiemstra, T.F.1    Charles, P.D.2    Hester, S.S.3
  • 10
    • 59949104184 scopus 로고    scopus 로고
    • Characterization of pkd protein-positive exosome-like vesicles
    • Hogan MC, Manganelli L, Woollard JR et al. Characterization of PKD protein-positive exosome-like vesicles. J Am Soc Nephrol 2009; 20: 278-288.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 278-288
    • Hogan, M.C.1    Manganelli, L.2    Woollard, J.R.3
  • 11
    • 84858792464 scopus 로고    scopus 로고
    • A novel evolutionarily conserved domain of cell-adhesion gpcrs mediates autoproteolysis
    • Arac D, Boucard AA, Bolliger MF et al. A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. EMBO J 2012; 31: 1364-1378.
    • (2012) EMBO J. , vol.31 , pp. 1364-1378
    • Arac, D.1    Boucard, A.A.2    Bolliger, M.F.3
  • 12
    • 82655181482 scopus 로고    scopus 로고
    • Epitope-tagged Pkhd1 tracks the processing, secretion, and localization of fibrocystin
    • Bakeberg JL, Tammachote R, Woollard JR et al. Epitope-tagged Pkhd1 tracks the processing, secretion, and localization of fibrocystin. J Am Soc Nephrol 2011; 22: 2266-2277.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 2266-2277
    • Bakeberg, J.L.1    Tammachote, R.2    Woollard, J.R.3
  • 13
    • 59949097474 scopus 로고    scopus 로고
    • Large-scale proteomics and phosphoproteomics of urinary exosomes
    • Gonzales PA, Pisitkun T, Hoffert JD et al. Large-scale proteomics and phosphoproteomics of urinary exosomes. J Am Soc Nephrol 2009; 20: 363-379.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 363-379
    • Gonzales, P.A.1    Pisitkun, T.2    Hoffert, J.D.3
  • 14
    • 33646161950 scopus 로고    scopus 로고
    • Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery
    • Zhou H, Yuen PS, Pisitkun T et al. Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery. Kidney Int 2006; 69: 1471-1476.
    • (2006) Kidney Int , vol.69 , pp. 1471-1476
    • Zhou, H.1    Yuen, P.S.2    Pisitkun, T.3
  • 15
    • 84862956256 scopus 로고    scopus 로고
    • Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT
    • Wang Z, Hill S, Luther JM et al. Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Proteomics 2012; 12: 329-338.
    • (2012) Proteomics , vol.12 , pp. 329-338
    • Wang, Z.1    Hill, S.2    Luther, J.M.3
  • 16
    • 84861678077 scopus 로고    scopus 로고
    • A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes
    • Raj DAA, Fiume I, Capasso G et al. A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Kidney Int 2012; 81: 1263-1272.
    • (2012) Kidney Int , vol.81 , pp. 1263-1272
    • Daa, R.1    Fiume, I.2    Capasso, G.3
  • 17
    • 0031004717 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human podocalyxin-like protein orthologous relationship to rabbit pclp1 and rat podocalyxin
    • Kershaw DB, Beck SG, Wharram BL et al. Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 and rat podocalyxin. J Biol Chem 1997; 272: 15708-15714.
    • (1997) J Biol Chem , vol.272 , pp. 15708-15714
    • Kershaw, D.B.1    Beck, S.G.2    Wharram, B.L.3
  • 18
    • 0036891810 scopus 로고    scopus 로고
    • Podocyte biology and response to injury
    • Mundel P, Shankland SJ. Podocyte biology and response to injury. J Am Soc Nephrol 2002; 13: 3005-3015.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 3005-3015
    • Mundel, P.1    Shankland, S.J.2
  • 19
    • 34948831564 scopus 로고    scopus 로고
    • In-depth proteomic profiling of the normal human kidney glomerulus using two-dimensional protein prefractionation in combination with liquid chromatography-tandem mass spectrometry
    • Miyamoto M, Yoshida Y, Taguchi I et al. In-depth proteomic profiling of the normal human kidney glomerulus using two-dimensional protein prefractionation in combination with liquid chromatography-tandem mass spectrometry. J Proteome Res 2007; 6: 3680-3690.
    • (2007) J Proteome Res , vol.6 , pp. 3680-3690
    • Miyamoto, M.1    Yoshida, Y.2    Taguchi, I.3
  • 20
    • 84899951088 scopus 로고    scopus 로고
    • In-depth proteomic analysis of podocin-rich exosomes in human urine
    • Denver, CO, USA
    • Hogan M. In-Depth Proteomic Analysis of Podocin-Rich Exosomes in Human Urine. JASN: Denver, CO, USA, 2010 pp F-PO1996.
    • (2010) JASN
    • Hogan, M.1
  • 21
    • 49849105549 scopus 로고    scopus 로고
    • Label-free detection of differential protein expression by lc/maldi mass spectrometry
    • Neubert H, Bonnert TP, Rumpel K et al. Label-free detection of differential protein expression by LC/MALDI mass spectrometry. J Proteome Res 2008; 7: 2270-2279.
    • (2008) J Proteome Res , vol.7 , pp. 2270-2279
    • Neubert, H.1    Bonnert, T.P.2    Rumpel, K.3
  • 22
    • 6044226889 scopus 로고    scopus 로고
    • Differential mass spectrometry: A label-free LC-MS method for finding significant differences in complex peptide and protein mixtures
    • Wiener MC, Sachs JR, Deyanova EG et al. Differential mass spectrometry: a label-free LC-MS method for finding significant differences in complex peptide and protein mixtures. Anal Chem 2004; 76: 6085-6096.
    • (2004) Anal Chem , vol.76 , pp. 6085-6096
    • Wiener, M.C.1    Sachs, J.R.2    Deyanova, E.G.3
  • 23
    • 84863518388 scopus 로고    scopus 로고
    • New aspects of membranoproliferative glomerulonephritis
    • Manenti L, Vaglio A, Buzio C. New aspects of membranoproliferative glomerulonephritis. N Engl J Med 2012; 367: 86-87.
    • (2012) N Engl J Med , vol.367 , pp. 86-87
    • Manenti, L.1    Vaglio, A.2    Buzio, C.3
  • 24
    • 77957786825 scopus 로고    scopus 로고
    • Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation
    • Vitureira N, Andrés R, Pérez-Mart?́nez E et al. Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PloS One 2010; 5: e12003.
    • (2010) PloS One , vol.5
    • Vitureira, N.1    Andrés, R.2    Pérez-Mart́nez, E.3
  • 25
    • 84863716980 scopus 로고    scopus 로고
    • Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters
    • Douglas LuW, Funkelstein L, Toneff T et al. Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters. J Neurochem 2012; 122: 512-522.
    • (2012) J Neurochem , vol.122 , pp. 512-522
    • Luw, D.1    Funkelstein, L.2    Toneff, T.3
  • 26
    • 65549114466 scopus 로고    scopus 로고
    • Membrane-bound proteinase 3 and its receptors: Relevance for the pathogenesis of Wegener's granulomatosis
    • Hu N, Westra J, Kallenberg CG. Membrane-bound proteinase 3 and its receptors: relevance for the pathogenesis of Wegener's granulomatosis. Autoimmun Rev 2009; 8: 510-514.
    • (2009) Autoimmun Rev , vol.8 , pp. 510-514
    • Hu, N.1    Westra, J.2    Kallenberg, C.G.3
  • 27
    • 80052769923 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics using q exactive, a high-performance benchtop quadrupole orbitrap mass spectrometer
    • M111 011015
    • Michalski A, Damoc E, Hauschild JP et al. Mass spectrometry-based proteomics using Q Exactive, a high-performance benchtop quadrupole Orbitrap mass spectrometer. Mol Cell Proteomics 2011; 10: M111 011015.
    • (2011) Mol Cell Proteomics , vol.10
    • Michalski, A.1    Damoc, E.2    Hauschild, J.P.3
  • 28
    • 20544440811 scopus 로고    scopus 로고
    • Apical cell membranes are shed into urine from injured podocytes: A novel phenomenon of podocyte injury
    • Hara M, Yanagihara T, Kihara I et al. Apical cell membranes are shed into urine from injured podocytes: a novel phenomenon of podocyte injury. J Am Soc Nephrol 2005; 16: 408-416.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 408-416
    • Hara, M.1    Yanagihara, T.2    Kihara, I.3
  • 29
    • 77956255640 scopus 로고    scopus 로고
    • Podocyte membrane vesicles in urine originate from tip vesiculation of podocyte microvilli
    • Hara M, Yanagihara T, Hirayama Y et al. Podocyte membrane vesicles in urine originate from tip vesiculation of podocyte microvilli. Hum Pathol 2010; 41: 1265-1275.
    • (2010) Hum Pathol , vol.41 , pp. 1265-1275
    • Hara, M.1    Yanagihara, T.2    Hirayama, Y.3
  • 30
    • 79959355048 scopus 로고    scopus 로고
    • Release of podocalyxin into the extracellular space Role of metalloproteinases
    • Fernandez D, Larrucea S, Nowakowski A et al. Release of podocalyxin into the extracellular space Role of metalloproteinases. Biochim Biophys Acta 2011; 1813: 1504-1510.
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 1504-1510
    • Fernandez, D.1    Larrucea, S.2    Nowakowski, A.3
  • 31
    • 84863740390 scopus 로고    scopus 로고
    • Biochemical and physical characterisation of urinary nanovesicles following chaps treatment
    • Musante L, Saraswat M, Duriez E et al. Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. PloS One 2012; 7: e37279.
    • (2012) PloS One , vol.7
    • Musante, L.1    Saraswat, M.2    Duriez, E.3
  • 32
    • 0033529312 scopus 로고    scopus 로고
    • Nephrin is specifically located at the slit diaphragm of glomerular podocytes
    • Ruotsalainen V, Ljungberg P, Wartiovaara J et al. Nephrin is specifically located at the slit diaphragm of glomerular podocytes. Proc Natl Acad Sci USA 1999; 96: 7962-7967.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7962-7967
    • Ruotsalainen, V.1    Ljungberg, P.2    Wartiovaara, J.3
  • 33
    • 20844461826 scopus 로고    scopus 로고
    • A mutation in the trpc6 cation channel causes familial focal segmental glomerulosclerosis
    • Winn MP, Conlon PJ, Lynn KL et al. A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science 2005; 308: 1801-1804.
    • (2005) Science , vol.308 , pp. 1801-1804
    • Winn, M.P.1    Conlon, P.J.2    Lynn, K.L.3
  • 34
    • 22844436647 scopus 로고    scopus 로고
    • TRPC6 is a glomerular slit diaphragmassociated channel required for normal renal function
    • Reiser J, Polu KR, Moller CC et al. TRPC6 is a glomerular slit diaphragmassociated channel required for normal renal function. Nat Genet 2005; 37: 739-744.
    • (2005) Nat Genet , vol.37 , pp. 739-744
    • Reiser, J.1    Polu, K.R.2    Moller, C.C.3
  • 35
    • 67649658244 scopus 로고    scopus 로고
    • M-type phospholipase A1 receptor as target antigen in idiopathic membranous nephropathy
    • Beck LH, Bonegio RGB, Lambeau G et al. M-type phospholipase A1 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 2009; 361: 11-21.
    • (2009) N Engl J Med , vol.361 , pp. 11-21
    • Beck, L.H.1    Rgb, B.2    Lambeau, G.3
  • 36
    • 49749121101 scopus 로고    scopus 로고
    • Urinary exosomal transcription factors, a new class of biomarkers for renal disease
    • Zhou H, Cheruvanky A, Hu X et al. Urinary exosomal transcription factors, a new class of biomarkers for renal disease. Kidney Int 2008; 74: 613-621.
    • (2008) Kidney Int , vol.74 , pp. 613-621
    • Zhou, H.1    Cheruvanky, A.2    Hu, X.3
  • 37
    • 79952174502 scopus 로고    scopus 로고
    • Focal segmental glomerulosclerosis plays a major role in the progression of iga nephropathy I. Immunohistochemical studies
    • Hill GS, Karoui KE, Karras A et al. Focal segmental glomerulosclerosis plays a major role in the progression of IgA nephropathy. I. Immunohistochemical studies. Kidney Int 2011; 79: 635-642.
    • (2011) Kidney Int , vol.79 , pp. 635-642
    • Hill, G.S.1    Karoui, K.E.2    Karras, A.3
  • 38
    • 0016667905 scopus 로고
    • Subcellular-localization and heterogeneity of neutral proteases in neutrophilic polymorphonuclear leukocytes
    • Dewald B, Rindlerludwig R, Bretz U et al. Subcellular-localization and heterogeneity of neutral proteases in neutrophilic polymorphonuclear leukocytes. J Exp Med 1975; 141: 709-723.
    • (1975) J Exp Med , vol.141 , pp. 709-723
    • Dewald, B.1    Rindlerludwig, R.2    Bretz, U.3
  • 39
    • 0025225389 scopus 로고
    • Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis
    • Csernok E, Ludemann J, Gross WL et al. Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis. Am J Pathol 1990; 137: 1113-1120.
    • (1990) Am J Pathol , vol.137 , pp. 1113-1120
    • Csernok, E.1    Ludemann, J.2    Gross, W.L.3
  • 40
    • 0025200694 scopus 로고
    • Identity of Wegener's autoantigen (p29) with proteinase 3 and myeloblastin [letter
    • Gupta S, Niles J, McCluskey R et al. Identity of Wegener's autoantigen (p29) with proteinase 3 and myeloblastin [letter]. Blood 1990; 76: 2162.
    • (1990) Blood , vol.76 , pp. 2162
    • Gupta, S.1    Niles, J.2    McCluskey, R.3
  • 41
    • 0009464172 scopus 로고
    • Antibiotic proteins of human polymorphonuclear leukocytes
    • Gabay JE, Scott RW, Campanelli D et al. Antibiotic proteins of human polymorphonuclear leukocytes. Proc Natl Acad Sci USA 1989; 86: 5610-5614.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5610-5614
    • Gabay, J.E.1    Scott, R.W.2    Campanelli, D.3
  • 42
    • 0025694843 scopus 로고
    • Cloning of cDNA for proteinase 3: A serine protease, antibiotic, and autoantigen from human neutrophils
    • Campanelli D, Melchior M, Fu Y et al. Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils. J Exp Med 1990; 172: 1709-1715.
    • (1990) J Exp Med , vol.172 , pp. 1709-1715
    • Campanelli, D.1    Melchior, M.2    Fu, Y.3
  • 43
    • 77957557995 scopus 로고    scopus 로고
    • Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome
    • Rood IM, Deegens JKJ, Merchant ML et al. Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome. Kidney Int 2010; 78: 810-816.
    • (2010) Kidney Int , vol.78 , pp. 810-816
    • Rood, I.M.1    Jkj, D.2    Merchant, M.L.3
  • 44
    • 34247872835 scopus 로고    scopus 로고
    • Rapid isolation of urinary exosomal biomarkers using a nanomembrane ultrafiltration concentrator
    • Cheruvanky A, Zhou H, Pisitkun T et al. Rapid isolation of urinary exosomal biomarkers using a nanomembrane ultrafiltration concentrator. Am J Physiol Renal Physiol 2007; 292: F1657-F1661.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Cheruvanky, A.1    Zhou, H.2    Pisitkun, T.3
  • 45
    • 0029060393 scopus 로고
    • Familial glomerulonephritis characterized by massive deposits of fibronectin
    • Assmann KJ, Koene RA, Wetzels JF. Familial glomerulonephritis characterized by massive deposits of fibronectin. Am J Kidney Dis 1995; 25: 781-791.
    • (1995) Am J Kidney Dis , vol.25 , pp. 781-791
    • Assmann, K.J.1    Koene, R.A.2    Wetzels, J.F.3
  • 46
    • 0029030009 scopus 로고
    • Glomerulopathy associated with predominant fibronectin deposits: A newly recognized hereditary disease
    • Strom EH, Banfi G, Krapf R et al. Glomerulopathy associated with predominant fibronectin deposits: a newly recognized hereditary disease. Kidney Int 1995; 48: 163-170.
    • (1995) Kidney Int , vol.48 , pp. 163-170
    • Strom, E.H.1    Banfi, G.2    Krapf, R.3
  • 47
    • 34547549299 scopus 로고    scopus 로고
    • Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculoacoustico-renal syndromes
    • Kantarci S, Al-Gazali L, Hill RS et al. Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculoacoustico- renal syndromes. Nat Genet 2007; 39: 957-959.
    • (2007) Nat Genet , vol.39 , pp. 957-959
    • Kantarci, S.1    Al-Gazali, L.2    Hill, R.S.3
  • 48
    • 0020664191 scopus 로고
    • Immunocytochemical localization of the Heymann nephritis antigen (GP330) in glomerular epithelial cells of normal Lewis rats
    • Kerjaschki D, Farquhar MG. Immunocytochemical localization of the Heymann nephritis antigen (GP330) in glomerular epithelial cells of normal Lewis rats. J Exp Med 1983; 157: 667-686.
    • (1983) J Exp Med , vol.157 , pp. 667-686
    • Kerjaschki, D.1    Farquhar, M.G.2
  • 49
    • 78650893224 scopus 로고    scopus 로고
    • A patient with cubilin deficiency
    • Storm T, Emma F, Verroust PJ et al. A patient with cubilin deficiency. N Engl J Med 2011; 364: 89-91.
    • (2011) N Engl J Med , vol.364 , pp. 89-91
    • Storm, T.1    Emma, F.2    Verroust, P.J.3
  • 50
    • 84860787585 scopus 로고    scopus 로고
    • Mutation analysis of nphs1 in a worldwide cohort of congenital nephrotic syndrome patients
    • Ovunc B, Ashraf S, Vega-Warner V et al. Mutation analysis of NPHS1 in a worldwide cohort of congenital nephrotic syndrome patients. Nephron Clin Pract 2012; 120: c139-c146.
    • (2012) Nephron Clin Pract , vol.120
    • Ovunc, B.1    Ashraf, S.2    Vega-Warner, V.3
  • 51
    • 54049137505 scopus 로고    scopus 로고
    • Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
    • Fremeaux-Bacchi V, Miller EC, Liszewski MK et al. Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome. Blood 2008; 112: 4948-4952.
    • (2008) Blood , vol.112 , pp. 4948-4952
    • Fremeaux-Bacchi, V.1    Miller, E.C.2    Liszewski, M.K.3
  • 52
    • 84863985862 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome in children: Complement mutations and clinical characteristics
    • Geerdink L, Westra D, van Wijk J et al. Atypical hemolytic uremic syndrome in children: complement mutations and clinical characteristics. Pediatr Nephrol 2012; 27: 1283-1291.
    • (2012) Pediatr Nephrol , vol.27 , pp. 1283-1291
    • Geerdink, L.1    Westra, D.2    Van Wijk, J.3
  • 53
    • 19444369542 scopus 로고    scopus 로고
    • Complement factor I: A susceptibility gene for atypical haemolytic uraemic syndrome
    • Fremeaux-Bacchi V, Dragon-Durey MA, Blouin J et al. Complement factor I: a susceptibility gene for atypical haemolytic uraemic syndrome. J Med Genet 2004; 41: e84.
    • (2004) J Med Genet , vol.41
    • Fremeaux-Bacchi, V.1    Dragon-Durey, M.A.2    Blouin, J.3
  • 54
    • 0034755959 scopus 로고    scopus 로고
    • Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes
    • Heath KE, Campos-Barros A, Toren A et al. Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes. Am J Hum Genet 2001; 69: 1033-1045.
    • (2001) Am J Hum Genet , vol.69 , pp. 1033-1045
    • Heath, K.E.1    Campos-Barros, A.2    Toren, A.3
  • 55
    • 79956071512 scopus 로고    scopus 로고
    • Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2 a predisposes mice to glomerulopathy
    • Johnstone DB, Zhang J, George B et al. Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2 a predisposes mice to glomerulopathy. Mol Cell Biol 2011; 31: 2162-2170.
    • (2011) Mol Cell Biol , vol.31 , pp. 2162-2170
    • Johnstone, D.B.1    Zhang, J.2    George, B.3
  • 56
    • 80051544854 scopus 로고    scopus 로고
    • Disruption of ptpro causes childhood-onset nephrotic syndrome
    • Ozaltin F, Ibsirlioglu T, Taskiran Ekim Z et al. Disruption of PTPRO causes childhood-onset nephrotic syndrome. Am J Hum Genet 2011; 89: 139-147.
    • (2011) Am J Hum Genet , vol.89 , pp. 139-147
    • Ozaltin, F.1    Ibsirlioglu, T.2    Taskiran Ekim, Z.3
  • 57
    • 77951257162 scopus 로고    scopus 로고
    • A novel mutation in the complement factor b gene (cfb) and atypical hemolytic uremic
    • Tawadrous H, Maga T, Sharma J et al. A novel mutation in the complement factor B gene (CFB) and atypical hemolytic uremic. syndrome. Pediatr Nephrol 2010; 25: 947-951.
    • (2010) Syndrome. Pediatr Nephrol , vol.25 , pp. 947-951
    • Tawadrous, H.1    Maga, T.2    Sharma, J.3
  • 58
    • 0033536599 scopus 로고    scopus 로고
    • Congenital nephrotic syndrome in mice lacking cd2-associated protein
    • Shih NY, Li J, Karpitskii V et al. Congenital nephrotic syndrome in mice lacking CD2-associated protein. Science 1999; 286: 312-315.
    • (1999) Science , vol.286 , pp. 312-315
    • Shih, N.Y.1    Li, J.2    Karpitskii, V.3
  • 59
    • 0038136885 scopus 로고    scopus 로고
    • CD2-Associated protein haploinsufficiency is linked to glomerular disease susceptibility
    • Kim JM, Wu H, Green G et al. CD2-Associated protein haploinsufficiency is linked to glomerular disease susceptibility. Science 2003; 300: 1298-1300.
    • (2003) Science , vol.300 , pp. 1298-1300
    • Kim, J.M.1    Wu, H.2    Green, G.3
  • 60
    • 0031835791 scopus 로고    scopus 로고
    • Expression of decay accelerating factor mRNA and complement C3 mRNA in human diseased kidney
    • Abe K, Miyazaki M, Koji T et al. Expression of decay accelerating factor mRNA and complement C3 mRNA in human diseased kidney. Kidney Int 1998; 54: 120-130.
    • (1998) Kidney Int , vol.54 , pp. 120-130
    • Abe, K.1    Miyazaki, M.2    Koji, T.3
  • 61
    • 0025827578 scopus 로고
    • Complement activation induces the expression of decay-accelerating factor on human mesangial cells
    • Shibata T, Cosio FG, Birmingham DJ. Complement activation induces the expression of decay-accelerating factor on human mesangial cells. J Immunol 1991; 147: 3901-3908.
    • (1991) J Immunol , vol.147 , pp. 3901-3908
    • Shibata, T.1    Cosio, F.G.2    Birmingham, D.J.3
  • 62
    • 0035469819 scopus 로고    scopus 로고
    • Antineutrophil cytoplasm autoantibodies from patients with systemic vasculitis activate neutrophils through distinct signaling cascades: Comparison with conventional Fcg receptor ligation
    • Ben-Smith A, Dove SK, Martin A et al. Antineutrophil cytoplasm autoantibodies from patients with systemic vasculitis activate neutrophils through distinct signaling cascades: comparison with conventional Fcg receptor ligation. Blood 2001; 98: 1448-1455.
    • (2001) Blood , vol.98 , pp. 1448-1455
    • Ben-Smith, A.1    Dove, S.K.2    Martin, A.3
  • 63
    • 79961028198 scopus 로고    scopus 로고
    • New perspectives on the renal slit diaphragm protein podocin
    • Relle M, Cash H, Brochhausen C et al. New perspectives on the renal slit diaphragm protein podocin. Mod Pathol 2011; 24: 1101-1110.
    • (2011) Mod Pathol , vol.24 , pp. 1101-1110
    • Relle, M.1    Cash, H.2    Brochhausen, C.3
  • 64
    • 84899912331 scopus 로고
    • Introduction
    • In: Jenis, Lowenthal (eds.), FA Davis: Philadelphia, P. A.
    • Jenis EH, Lowenthal DT. Introduction. In: Jenis, Lowenthal (eds.), Kidney Biopsy Interpretation. FA Davis: Philadelphia, PA, 1977.
    • (1977) Kidney Biopsy Interpretation
    • Jenis, E.H.1    Lowenthal, D.T.2
  • 65
    • 4944239350 scopus 로고    scopus 로고
    • CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin
    • Karamatic Crew V, Burton N, Kagan A et al. CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin. Blood 2004; 104: 2217-2223.
    • (2004) Blood , vol.104 , pp. 2217-2223
    • Karamatic Crew, V.1    Burton, N.2    Kagan, A.3
  • 66
    • 33749551723 scopus 로고    scopus 로고
    • Kidney failure in mice lacking the tetraspanin CD151
    • Sachs N, Kreft M, van den Bergh Weerman MA et al. Kidney failure in mice lacking the tetraspanin CD151. J Cell Biol 2006; 175: 33-39.
    • (2006) J Cell Biol , vol.175 , pp. 33-39
    • Sachs, N.1    Kreft, M.2    Van Den Bergh3    Weerman, M.A.4
  • 67
    • 79951636263 scopus 로고    scopus 로고
    • CD151 expression can predict cancer progression in clear cell renal cell carcinoma
    • Yoo SH, Lee K, Chae JY et al. CD151 expression can predict cancer progression in clear cell renal cell carcinoma. Histopathology 2011; 58: 191-197.
    • (2011) Histopathology , vol.58 , pp. 191-197
    • Yoo, S.H.1    Lee, K.2    Chae, J.Y.3
  • 68
    • 53149111544 scopus 로고    scopus 로고
    • Deletion of Cd151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane
    • Roselli S, Baleato RM, Guthrie PL et al. Deletion of Cd151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane. Am J Pathol 2008; 173: 927-937.
    • (2008) Am J Pathol , vol.173 , pp. 927-937
    • Roselli, S.1    Baleato, R.M.2    Guthrie, P.L.3
  • 69
    • 84855433172 scopus 로고    scopus 로고
    • Blood pressure influences end-stage renal disease of Cd151 knockout mice
    • Sachs N, Claessen N, Aten J et al. Blood pressure influences end-stage renal disease of Cd151 knockout mice. J Clin Investig 2012; 122: 348-358.
    • (2012) J Clin Investig , vol.122 , pp. 348-358
    • Sachs, N.1    Claessen, N.2    Aten, J.3
  • 70
    • 84859826518 scopus 로고    scopus 로고
    • Integrin a3 mutations with kidney, lung, and skin disease
    • Has C, Sparta G, Kiritsi D et al. Integrin a3 mutations with kidney, lung, and skin disease. N Engl J Med 2012; 366: 1508-1514.
    • (2012) N Engl J Med , vol.366 , pp. 1508-1514
    • Has, C.1    Sparta, G.2    Kiritsi, D.3
  • 71
    • 84870522502 scopus 로고    scopus 로고
    • Gain of glycosylation in integrin a3 causes lung disease and nephrotic syndrome
    • Nicolaou N, Margadant C, Kevelam SH et al. Gain of glycosylation in integrin a3 causes lung disease and nephrotic syndrome. J Clin Investig 2012 0 122: 4375-4387.
    • (2012) J Clin Investig , vol.122 , pp. 4375-4387
    • Nicolaou, N.1    Margadant, C.2    Kevelam, S.H.3
  • 72
    • 84878851636 scopus 로고    scopus 로고
    • ARHGDIA: A novel gene implicated in nephrotic syndrome
    • Gupta IR, Baldwin C, Auguste D et al. ARHGDIA: a novel gene implicated in nephrotic syndrome. J Med Genet 2013; 50: 330-338.
    • (2013) J Med Genet , vol.50 , pp. 330-338
    • Gupta, I.R.1    Baldwin, C.2    Auguste, D.3
  • 73
    • 84881245920 scopus 로고    scopus 로고
    • ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling
    • Gee HY, Saisawat P, Ashraf S et al. ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling. J Clin Investig 2013; 123: 3243-3253.
    • (2013) J Clin Investig , vol.123 , pp. 3243-3253
    • Gee, H.Y.1    Saisawat, P.2    Ashraf, S.3
  • 74
    • 0032523830 scopus 로고    scopus 로고
    • Primary structure and high expression of human agrin in basement membranes of adult lung and kidney
    • Groffen AJA, Buskens CAF, van Kuppevelt TH et al. Primary structure and high expression of human agrin in basement membranes of adult lung and kidney. Eur J Biochem 1998; 254: 123-128.
    • (1998) Eur J Biochem , vol.254 , pp. 123-128
    • Aja, G.1    Caf, B.2    Van Kuppevelt, T.H.3
  • 75
    • 79960877647 scopus 로고    scopus 로고
    • MYO1E mutations and childhood familial focal segmental glomerulosclerosis
    • Mele C, Iatropoulos P, Donadelli R et al. MYO1E mutations and childhood familial focal segmental glomerulosclerosis. N Engl J Med 2011; 365: 295-306.
    • (2011) N Engl J Med , vol.365 , pp. 295-306
    • Mele, C.1    Iatropoulos, P.2    Donadelli, R.3
  • 76
    • 36749048702 scopus 로고    scopus 로고
    • Elastase deposits in the kidney and urinary elastase excretion in patients with glomerulonephritis-evidence for neutrophil involvement in renal injury
    • Kuźniar J, Kuźniar TJ, Marchewka Z et al. Elastase deposits in the kidney and urinary elastase excretion in patients with glomerulonephritis-evidence for neutrophil involvement in renal injury. Scand J Urol Nephrol 2007; 41: 527-534.
    • (2007) Scand J Urol Nephrol , vol.41 , pp. 527-534
    • Kuźniar, J.1    Kuźniar, T.J.2    Marchewka, Z.3
  • 77
    • 84855171766 scopus 로고    scopus 로고
    • INF2 mutations in charcot-marie-tooth disease with glomerulopathy
    • Boyer O, Nevo F, Plaisier E et al. INF2 mutations in charcot-marie-tooth disease with glomerulopathy. N Engl J Med 2011; 365: 2377-2388.
    • (2011) N Engl J Med , vol.365 , pp. 2377-2388
    • Boyer, O.1    Nevo, F.2    Plaisier, E.3
  • 78
    • 79960404942 scopus 로고    scopus 로고
    • Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy
    • Roesli C, Fugmann T, Borgia B et al. Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy. Kidney Int 2011; 80: 272-281.
    • (2011) Kidney Int , vol.80 , pp. 272-281
    • Roesli, C.1    Fugmann, T.2    Borgia, B.3
  • 79
    • 58149510603 scopus 로고    scopus 로고
    • Disruption of myosin 1e promotes podocyte injury
    • Krendel M, Kim SV, Willinger T et al. Disruption of myosin 1e promotes podocyte injury. J Am Soc Nephrol 2009; 20: 86-94.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 86-94
    • Krendel, M.1    Kim, S.V.2    Willinger, T.3
  • 80
    • 80052272947 scopus 로고    scopus 로고
    • Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome
    • Sanna-Cherchi S, Burgess KE, Nees SN et al. Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome. Kidney Int 2011; 80: 389-396.
    • (2011) Kidney Int , vol.80 , pp. 389-396
    • Sanna-Cherchi, S.1    Burgess, K.E.2    Nees, S.N.3
  • 81
    • 53549100724 scopus 로고    scopus 로고
    • Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis
    • Kain R, Exner M, Brandes R et al. Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis. Nat Med 2008; 14: 1088-1096.
    • (2008) Nat Med , vol.14 , pp. 1088-1096
    • Kain, R.1    Exner, M.2    Brandes, R.3
  • 82
    • 84861634101 scopus 로고    scopus 로고
    • Elevated antilysosomalassociated membrane protein-2 antibody levels in patients with adult Henoch-Schonlein purpura
    • Kawakami T, Takeuchi S, Arimura Y et al. Elevated antilysosomalassociated membrane protein-2 antibody levels in patients with adult Henoch-Schonlein purpura. Br J Dermatol 2012; 166: 1206-1212.
    • (2012) Br J Dermatol , vol.166 , pp. 1206-1212
    • Kawakami, T.1    Takeuchi, S.2    Arimura, Y.3
  • 83
    • 68549109719 scopus 로고    scopus 로고
    • Cortactin interacts with podocalyxin and mediates morphological change of podocytes through its phosphorylation
    • Kobayashi T, Notoya M, Shinosaki T et al. Cortactin interacts with podocalyxin and mediates morphological change of podocytes through its phosphorylation. Nephron Exp Nephrol 2009; 113: e89-e96.
    • (2009) Nephron Exp Nephrol , vol.113
    • Kobayashi, T.1    Notoya, M.2    Shinosaki, T.3
  • 84
    • 60749131946 scopus 로고    scopus 로고
    • Rab 23 is expressed in the glomerulus and plays a role in the development of focal segmental glomerulosclerosis
    • Huang T-H, Shui H-A, Ka S-M et al. Rab 23 is expressed in the glomerulus and plays a role in the development of focal segmental glomerulosclerosis. Nephrol Dialysis Transplant 2009; 24: 743-754.
    • (2009) Nephrol Dialysis Transplant , vol.24 , pp. 743-754
    • Huang, T.-H.1    Shui, H.-A.2    Ka, S.-M.3
  • 85
    • 79960404942 scopus 로고    scopus 로고
    • Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy
    • Fugmann T, Borgia B, Revesz C et al. Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy. Kidney Int 2011; 80: 272-281.
    • (2011) Kidney Int , vol.80 , pp. 272-281
    • Fugmann, T.1    Borgia, B.2    Revesz, C.3
  • 86
    • 0031726568 scopus 로고    scopus 로고
    • The plasma membrane-actin linking protein, ezrin, is a glomerular epithelial cell marker in glomerulogenesis, in the adult kidney and in glomerular injury
    • Hugo C, Nangaku M, Shankland SJ et al. The plasma membrane-actin linking protein, ezrin, is a glomerular epithelial cell marker in glomerulogenesis, in the adult kidney and in glomerular injury. Kidney Int 1998; 54: 1934-1944.
    • (1998) Kidney Int , vol.54 , pp. 1934-1944
    • Hugo, C.1    Nangaku, M.2    Shankland, S.J.3
  • 87
    • 48349125616 scopus 로고    scopus 로고
    • Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease
    • Saburi S, Hester I, Fischer E et al. Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet 2008; 40: 1010-1015.
    • (2008) Nat Genet , vol.40 , pp. 1010-1015
    • Saburi, S.1    Hester, I.2    Fischer, E.3
  • 88
    • 0042035606 scopus 로고    scopus 로고
    • CD59a deficiency exacerbates accelerated nephrotoxic nephritis in mice
    • Turnberg D, Botto M, Warren J et al. CD59a deficiency exacerbates accelerated nephrotoxic nephritis in mice. J Am Soc Nephrol 2003; 14: 2271-2279.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2271-2279
    • Turnberg, D.1    Botto, M.2    Warren, J.3
  • 89
    • 84862788899 scopus 로고    scopus 로고
    • New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2
    • Praekelt U, Kopp PM, Rehm K et al. New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2. Eur J Cell Biol 2012; 91: 180-191.
    • (2012) Eur J Cell Biol , vol.91 , pp. 180-191
    • Praekelt, U.1    Kopp, P.M.2    Rehm, K.3
  • 90
    • 0033543763 scopus 로고    scopus 로고
    • Identification of syntenin as a protein of the apical early endocytic compartment in Madin-Darby canine kidney cells
    • Fialka I, Steinlein P, Ahorn H et al. Identification of syntenin as a protein of the apical early endocytic compartment in Madin-Darby canine kidney cells. J Biol Chem 1999; 274: 26233-26239.
    • (1999) J Biol Chem , vol.274 , pp. 26233-26239
    • Fialka, I.1    Steinlein, P.2    Ahorn, H.3
  • 91
    • 84861183922 scopus 로고    scopus 로고
    • Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney
    • Westwood BM, Chappell MC. Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney. Peptides 2012; 35: 190-195.
    • (2012) Peptides , vol.35 , pp. 190-195
    • Westwood, B.M.1    Chappell, M.C.2
  • 92
    • 0037182728 scopus 로고    scopus 로고
    • Brief report-antenatal membranous glomerulonephritis due to anti-neutral endopeptidase antibodies
    • Debiec H, Guigonis V, Mougenot B et al. Brief report-antenatal membranous glomerulonephritis due to anti-neutral endopeptidase antibodies. N Engl J Med 2002; 346: 2053-2060.
    • (2002) N Engl J Med , vol.346 , pp. 2053-2060
    • Debiec, H.1    Guigonis, V.2    Mougenot, B.3
  • 93
    • 0348049699 scopus 로고    scopus 로고
    • Podocyte cytoskeleton is connected to the integral membrane protein podocalyxin through Naþ/Hþ-exchanger regulatory factor 2 and ezrin
    • Takeda T. Podocyte cytoskeleton is connected to the integral membrane protein podocalyxin through Naþ/Hþ-exchanger regulatory factor 2 and ezrin. Clin Exp Nephrol 2003; 7: 260-269.
    • (2003) Clin Exp Nephrol , vol.7 , pp. 260-269
    • Takeda, T.1
  • 94
    • 0034721906 scopus 로고    scopus 로고
    • A human homolog of angiotensinconverting enzyme: Cloning and functional expression as a captoprilinsensitive carboxypeptidase
    • Tipnis SR, Hooper NM, Hyde R et al. A human homolog of angiotensinconverting enzyme: cloning and functional expression as a captoprilinsensitive carboxypeptidase. J Biol Chem 2000; 275: 33238-33243.
    • (2000) J Biol Chem , vol.275 , pp. 33238-33243
    • Tipnis, S.R.1    Hooper, N.M.2    Hyde, R.3
  • 95
    • 33750722109 scopus 로고    scopus 로고
    • Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: Implications for albuminuria in diabetes
    • Ye M, Wysocki J, William J et al. Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: implications for albuminuria in diabetes. J Am Soc Nephrol 2006; 17: 3067-3075.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3067-3075
    • Ye, M.1    Wysocki, J.2    William, J.3
  • 96
    • 66749171697 scopus 로고    scopus 로고
    • Statistical design of quantitative mass spectrometrybased proteomic experiments
    • Oberg AL, Vitek O. Statistical design of quantitative mass spectrometrybased proteomic experiments. J Proteome Res 2009; 8: 2144-2156.
    • (2009) J Proteome Res , vol.8 , pp. 2144-2156
    • Oberg, A.L.1    Vitek, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.