Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters

Journal of Neurochemistry

Volumn 122, Issue 3, 2012, Pages 512-522

  Douglas Lu, Weiya ^a   Funkelstein, Lydiane ^a   Toneff, Thomas ^a   Reinheckel, Thomas ^b   Peters, Christoph ^b   Hook, Vivian ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

aminopeptidase; cathepsin H; enkephalin; galanin; peptide neurotransmitter; protease

Indexed keywords

AMINOPEPTIDASE; ARGININE; CATHEPSIN H; GALANIN; LYSINE; METENKEPHALIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CATHEPSIN H GENE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; COW; DOWN REGULATION; ENZYME ACTIVITY; GENE; GENE INACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE MICROSCOPY; IN VIVO STUDY; NEUROCHEMISTRY; NEUROTRANSMITTER RELEASE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SECRETORY VESICLE; TANDEM MASS SPECTROMETRY;

ADRENAL MEDULLA; AMINO ACID SEQUENCE; ANIMALS; BRAIN; CATHEPSIN H; CATTLE; CELLS, CULTURED; CHROMAFFIN CELLS; ENKEPHALIN, METHIONINE; GALANIN; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; RADIOIMMUNOASSAY; SECRETORY VESICLES; TANDEM MASS SPECTROMETRY;

MUS;

EID: 84863716980     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07788.x     Document Type: Article

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