Orally administered lycopene attenuates diethylnitrosamine-induced hepatocarcinogenesis in rats by modulating Nrf-2/HO-1 and Akt/mTOR pathways

Nutrition and Cancer

Volumn 66, Issue 4, 2014, Pages 590-598

  Sahin, Kazim ^a   Orhan, Cemal ^a   Tuzcu, Mehmet ^a   Sahin, Nurhan ^a   Ali, Shakir ^b   Bahcecioglu, Ibrahim H ^a   Guler, Osman ^c   Ozercan, Ibrahim ^a   Ilhan, Necip ^a   Kucuk, Omer ^d  

^a FIRAT UNIVERSITY   (Turkey)

^b HAMDARD UNIVERSITY   (India)

^c Veterinary Control Institute   (Turkey)

^d EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CATALASE; CYCLOOXYGENASE 2; DIETHYLNITROSAMINE; GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; LYCOPENE; MALONALDEHYDE; MAMMALIAN TARGET OF RAPAMYCIN; PHENOBARBITAL; PROTEIN KINASE B; S6 KINASE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; CAROTENOID; GLUTATHIONE; HEME OXYGENASE; HMOX1 PROTEIN, RAT; MTOR PROTEIN, RAT; NFE2L2 PROTEIN, RAT; PTGS2 PROTEIN, RAT; TARGET OF RAPAMYCIN KINASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CANCER SIZE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; LIVER CARCINOGENESIS; LIVER INJURY; LIVER NODULE; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; ANIMAL; BLOOD; CHEMICALLY INDUCED; GENETICS; LIVER NEOPLASMS; METABOLISM; ORAL DRUG ADMINISTRATION; SIGNAL TRANSDUCTION; WISTAR RAT;

MAMMALIA; RATTUS;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; BILIRUBIN; CAROTENOIDS; CATALASE; CYCLOOXYGENASE 2; DIETHYLNITROSAMINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEME OXYGENASE (DECYCLIZING); LIVER NEOPLASMS; MALE; MALONDIALDEHYDE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TOR SERINE-THREONINE KINASES;

EID: 84899944299     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2014.894092     Document Type: Article

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