Thymoquinone attenuates diethylnitrosamine induction of hepatic carcinogenesis through antioxidant signaling

Oxidative Medicine and Cellular Longevity

Volumn 3, Issue 4, 2010, Pages 254-261

  Sayed Ahmed, Mohamed M ^a   Aleisa, Abdulaziz M ^a   Al Rejaie, Salim S ^a   Al Yahya, Abdulaziz A ^a   Al Shabanah, Othman A ^a   Hafez, Mohamed M ^a   Nagi, Mahmoud N ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Diethylnitrosamine; Gene expression; Hepatic carcinogenesis; Thymoquinone

Indexed keywords

ALKALINE PHOSPHATASE; ANTIOXIDANT ENZYME; ANTIOXIDANT PROPERTIES; BEST STRATEGY; CANCER MORTALITY; CHEMOPREVENTION; CONTROL VALUES; DIETHYLNITROSAMINE; DRINKING WATER; FOUR-GROUP; GLUTATHIONE PEROXIDASE; GLUTATHIONE-S-TRANSFERASE; GROUP 4; HEPATIC CARCINOGENESIS; HEPATOCARCINOGENESIS; HEPATOCELLULAR CARCINOMA; INTRAPERITONEAL; LIVER CANCERS; LIVER TISSUE; MRNA EXPRESSION; REDUCED GLUTATHIONE; SINGLE-DOSE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; THYMOQUINONE;

ANIMALS; DISEASES; LIVER; PATHOLOGY; PHOSPHATASES; POTABLE WATER; RATS;

GENE EXPRESSION;

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTIOXIDANT; BILIRUBIN; CATALASE; DIETHYLNITROSAMINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; NITRATE; NITRITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THYMOQUINONE; BENZOQUINONE DERIVATIVE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BILIRUBIN BLOOD LEVEL; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER; LIVER CARCINOGENESIS; LIVER FUNCTION; LIVER INJURY; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; TREATMENT OUTCOME; ANIMAL; BLACK CUMIN; CARCINOMA, HEPATOCELLULAR; DIETARY SUPPLEMENT; LIVER NEOPLASMS; METABOLISM; WISTAR RAT;

ANIMALIA; NIGELLA SATIVA; RATTUS;

ANIMALS; ANTIOXIDANTS; BENZOQUINONES; CARCINOMA, HEPATOCELLULAR; DIETARY SUPPLEMENTS; DIETHYLNITROSAMINE; LIVER NEOPLASMS; MALE; NIGELLA SATIVA; RATS; RATS, WISTAR;

EID: 77957377544     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.4161/oxim.3.4.12714     Document Type: Article

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