Synergy of mIL-21 and mIL-15 in enhancing DNA vaccine efficacy against acute and chronic Toxoplasma gondii infection in mice

Vaccine

Volumn 32, Issue 25, 2014, Pages 3058-3065

  Li, Zhong Yuan ^a,b   Chen, Jia ^a   Petersen, Eskild ^c   Zhou, Dong Hui ^a   Huang, Si Yang ^a   Song, Hui Qun ^a   Zhu, Xing Quan ^a,b  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY   (China)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

DNA vaccine; MIL 15; MIL 21; Protective immunity; Synergy; TgMIC8; Toxoplasma gondii; Toxoplasmosis

Indexed keywords

CHLORMETHINE; DNA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; HUMORAL IMMUNITY; IMMUNE RESPONSE; IN VITRO STUDY; LETHAL DOSE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE LOAD; PRIORITY JOURNAL; SPLEEN CELL; SURVIVAL TIME; TOXOPLASMOSIS;

DNA VACCINE; MIL-15; MIL-21; PROTECTIVE IMMUNITY; SYNERGY; TGMIC8; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; FEMALE; GENETIC VECTORS; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; INTERLEUKIN-15; INTERLEUKINS; MICE; PLASMIDS; PROTOZOAN VACCINES; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; VACCINES, DNA;

EID: 84899935171     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.03.042     Document Type: Article

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