Immune responses to pneumococcal pilus RrgA and RrgB antigens and their relationship with pneumococcal carriage in humans

Journal of Infection

Volumn 68, Issue 6, 2014, Pages 562-571

  Ahmed, Muhammad S ^a   Derbyshire, Stephen ^b   Flanagan, Brian ^a   Loh, Christopher ^b   Mccormick, Max ^c   Barocchi, Michele ^d   Masignani, Vega ^d   Finn, Adam ^e   Zhang, Qibo ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ALDER HEY CHILDREN S HOSPITAL   (United Kingdom)

^c ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^d NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^e UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

B cell response; Nasopharynx associated lymphoid tissue (NALT); Pilus proteins; Pneumococcal carriage; Serum antibody; Streptococcus pneumoniae

Indexed keywords

ADHESIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; PROTEIN ANTIBODY; RRGA ANTIGEN; RRGB ANTIGEN; STREPTOCOCCUS ANTIGEN; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; FIMBRIA PROTEIN; RRGA PROTEIN, STREPTOCOCCUS PNEUMONIAE; VIRULENCE FACTOR;

ADAPTIVE IMMUNITY; ADENOTONSILLAR MONONUCLEAR CELL; ADOLESCENT; ADULT; AGE DISTRIBUTION; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIUM CARRIER; BACTERIUM CULTURE; BACTERIUM PILUS; CHILD; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOBLOTTING; LYMPHOID TISSUE; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; NASOPHARYNX; PNEUMOCOCCAL CARRIAGE; PRESCHOOL CHILD; RRGC GENE; SCHOOL CHILD; STREPTOCOCCUS PNEUMONIAE; ANIMAL; BLOOD; FIMBRIA; HETEROZYGOTE; IMMUNOLOGY; INFANT; ISOLATION AND PURIFICATION; MICROBIOLOGY; PNEUMOCOCCAL INFECTION; SALIVA; SERUM; YOUNG ADULT;

ADOLESCENT; ADULT; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; B-LYMPHOCYTES; CARRIER STATE; CHILD; CHILD, PRESCHOOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; ENZYME-LINKED IMMUNOSPOT ASSAY; FEMALE; FIMBRIAE PROTEINS; FIMBRIAE, BACTERIAL; HUMANS; IMMUNOBLOTTING; INFANT; MALE; PNEUMOCOCCAL INFECTIONS; SALIVA; SERUM; STREPTOCOCCUS PNEUMONIAE; VIRULENCE FACTORS; YOUNG ADULT;

EID: 84899934670     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2014.01.013     Document Type: Article

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