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Volumn 75, Issue 1, 2007, Pages 350-357

Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM POTASSIUM SULFATE; BACTERIAL ANTIGEN; IMJECT; PLACEBO; PNEUMOLYSIN TOXOID; PROTEIN PDB; PROTEIN PHTB; PROTEIN PHTE; PROTEIN PSPA; PROTEIN PSPC; STREPTOCOCCUS VACCINE; UNCLASSIFIED DRUG;

EID: 33845980590     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01103-06     Document Type: Article
Times cited : (163)

References (51)
  • 1
    • 0037222927 scopus 로고    scopus 로고
    • Genetic alteration of capsule type but not PspA type affects accessibility of surface-bound complement and surface antigens of Streptococcus pneumoniae
    • Abeyta, M., G. G. Hardy, and J. Yother. 2003. Genetic alteration of capsule type but not PspA type affects accessibility of surface-bound complement and surface antigens of Streptococcus pneumoniae. Infect. Immun. 71:218-225.
    • (2003) Infect. Immun , vol.71 , pp. 218-225
    • Abeyta, M.1    Hardy, G.G.2    Yother, J.3
  • 3
    • 0028028168 scopus 로고
    • Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae
    • Alexander, J. E., R. A. Lock, C. C. A. M. Peeters, J. T. Poolman, P. W. Andrew, T. J. Mitchell, D. Hansman, and J. C. Paton. 1994. Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae. Infect. Immun. 62:5683-5688.
    • (1994) Infect. Immun , vol.62 , pp. 5683-5688
    • Alexander, J.E.1    Lock, R.A.2    Peeters, C.C.A.M.3    Poolman, J.T.4    Andrew, P.W.5    Mitchell, T.J.6    Hansman, D.7    Paton, J.C.8
  • 4
    • 84983711696 scopus 로고
    • Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III
    • Avery, O. T., C. M. MacLeod, and M. McCarty. 1944. Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III. J. Exp. Med. 79:137-158.
    • (1944) J. Exp. Med , vol.79 , pp. 137-158
    • Avery, O.T.1    MacLeod, C.M.2    McCarty, M.3
  • 5
    • 0036118026 scopus 로고    scopus 로고
    • The role of pneumococcal surface protein C (PspC) in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae
    • Balachandran, P., A. Brooks-Walter, A. Virolainen-Julkunen, S. K. Hollingshead, and D. E. Briles. 2002. The role of pneumococcal surface protein C (PspC) in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae. Infect. Immun. 70:2526-2534.
    • (2002) Infect. Immun , vol.70 , pp. 2526-2534
    • Balachandran, P.1    Brooks-Walter, A.2    Virolainen-Julkunen, A.3    Hollingshead, S.K.4    Briles, D.E.5
  • 6
    • 0029846414 scopus 로고    scopus 로고
    • Sequence heterogeneity of PsaA, a 37-kDa putative adhesin essential for virulence of Streptococcus pneumoniae
    • Berry, A. M., and J. C. Paton. 1996. Sequence heterogeneity of PsaA, a 37-kDa putative adhesin essential for virulence of Streptococcus pneumoniae. Infect. Immun. 64:5255-5262.
    • (1996) Infect. Immun , vol.64 , pp. 5255-5262
    • Berry, A.M.1    Paton, J.C.2
  • 7
    • 0033981143 scopus 로고    scopus 로고
    • Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative pneumococcal virulence proteins
    • Berry, A. M., and J. C. Paton. 2000. Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative pneumococcal virulence proteins. Infect. Immun. 68:133-140.
    • (2000) Infect. Immun , vol.68 , pp. 133-140
    • Berry, A.M.1    Paton, J.C.2
  • 8
    • 0025989653 scopus 로고
    • Structure and function of pneumolysin, the multifunctional, thiol-activated toxin of Streptococcus pneumoniae
    • Boulnois, G. J., J. C. Paton, T. J. Mitchell, and P. W. Andrew. 1991. Structure and function of pneumolysin, the multifunctional, thiol-activated toxin of Streptococcus pneumoniae. Mol. Microbiol. 5:2611-2616.
    • (1991) Mol. Microbiol , vol.5 , pp. 2611-2616
    • Boulnois, G.J.1    Paton, J.C.2    Mitchell, T.J.3    Andrew, P.W.4
  • 9
    • 4544282640 scopus 로고    scopus 로고
    • Typing of pneumococcal surface protein A (PspA) in Streptococcus pneumoniae isolated during epidemiological surveillance in Brazil: Towards novel pneumococcal protein vaccines
    • Brandileone, M. C., A. L. Andrade, E. M. Teles, R. C. Zanella, T. I. Yara, J. L. Di Fabio, and S. K. Hollingshead. 2004. Typing of pneumococcal surface protein A (PspA) in Streptococcus pneumoniae isolated during epidemiological surveillance in Brazil: towards novel pneumococcal protein vaccines. Vaccine 22:3890-3896.
    • (2004) Vaccine , vol.22 , pp. 3890-3896
    • Brandileone, M.C.1    Andrade, A.L.2    Teles, E.M.3    Zanella, R.C.4    Yara, T.I.5    Di Fabio, J.L.6    Hollingshead, S.K.7
  • 10
    • 0033984377 scopus 로고    scopus 로고
    • Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae
    • Briles, D. E., E. Ades, J. C. Paton, J. S. Sampson, G. M. Carlone, R. C. Huebner, A. Virolainen, E. Swiatlo, and S. K. Hollingshead. 2000. Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae. Infect. Immun. 68:796-800.
    • (2000) Infect. Immun , vol.68 , pp. 796-800
    • Briles, D.E.1    Ades, E.2    Paton, J.C.3    Sampson, J.S.4    Carlone, G.M.5    Huebner, R.C.6    Virolainen, A.7    Swiatlo, E.8    Hollingshead, S.K.9
  • 11
    • 0033680686 scopus 로고    scopus 로고
    • Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA
    • Briles, D. E., S. K. Hollingshead, J. King, A. Swift, P. A. Braun, M. K. Park, L. M. Ferguson, M. H. Nahm, and G. S. Nabors. 2000. Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA. J. Infect. Dis. 182:1694-1701.
    • (2000) J. Infect. Dis , vol.182 , pp. 1694-1701
    • Briles, D.E.1    Hollingshead, S.K.2    King, J.3    Swift, A.4    Braun, P.A.5    Park, M.K.6    Ferguson, L.M.7    Nahm, M.H.8    Nabors, G.S.9
  • 12
    • 0042665483 scopus 로고    scopus 로고
    • Briles, D. E., S. K. Hollingshead, J. C. Paton, E. W. Ades, L. Novak, F. W. Van Ginkel, and W. H. Benjamin, Jr. 2003. Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae. J. Infect. Dis. 188:339-348.
    • Briles, D. E., S. K. Hollingshead, J. C. Paton, E. W. Ades, L. Novak, F. W. Van Ginkel, and W. H. Benjamin, Jr. 2003. Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae. J. Infect. Dis. 188:339-348.
  • 13
    • 0032721182 scopus 로고    scopus 로고
    • The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia
    • Brooks-Walter, A., D. E. Briles, and S. K. Hollingshead. 1999. The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia. Infect. Immun. 67:6533-6542.
    • (1999) Infect. Immun , vol.67 , pp. 6533-6542
    • Brooks-Walter, A.1    Briles, D.E.2    Hollingshead, S.K.3
  • 14
    • 0034778154 scopus 로고    scopus 로고
    • Immunization with components of two iron uptake ABC transporters protects mice against systemic Streptococcus pneumoniae infection
    • Brown, J. S., A. D. Ogunniyi, M. C. Woodrow, D. W. Holden, and J. C. Paton. 2001. Immunization with components of two iron uptake ABC transporters protects mice against systemic Streptococcus pneumoniae infection. Infect. Immun. 69:6702-6706.
    • (2001) Infect. Immun , vol.69 , pp. 6702-6706
    • Brown, J.S.1    Ogunniyi, A.D.2    Woodrow, M.C.3    Holden, D.W.4    Paton, J.C.5
  • 15
    • 0025034304 scopus 로고
    • Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae
    • Crain, M. J., W. D. Waltman II, J. S. Turner, J. Yother, D. F. Talkington, L. S. McDaniel, B. M. Gray, and D. E. Briles. 1990. Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae. Infect. Immun. 58:3293-3299.
    • (1990) Infect. Immun , vol.58 , pp. 3293-3299
    • Crain, M.J.1    Waltman II, W.D.2    Turner, J.S.3    Yother, J.4    Talkington, D.F.5    McDaniel, L.S.6    Gray, B.M.7    Briles, D.E.8
  • 16
    • 0029165459 scopus 로고
    • Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor
    • Cundell, D. R., N. P. Gerald, C. Gerald, I. Idanpaan-Heikkila, and E. I. Tuomanen. 1995. Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature 377:435-438.
    • (1995) Nature , vol.377 , pp. 435-438
    • Cundell, D.R.1    Gerald, N.P.2    Gerald, C.3    Idanpaan-Heikkila, I.4    Tuomanen, E.I.5
  • 17
    • 0028609712 scopus 로고
    • Receptor specificity of adherence of Streptococcus pneumoniae to human type-II pneumocytes and vascular endothelial cells in vitro
    • Cundell, D. R., and E. I. Tuomanen. 1994. Receptor specificity of adherence of Streptococcus pneumoniae to human type-II pneumocytes and vascular endothelial cells in vitro. Microb. Pathog. 17:361-374.
    • (1994) Microb. Pathog , vol.17 , pp. 361-374
    • Cundell, D.R.1    Tuomanen, E.I.2
  • 18
    • 0030868591 scopus 로고    scopus 로고
    • Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases
    • Dintilhac, A., G. Alloing, C. Granadel, and J.-P. Claverys. 1997. Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases. Mol. Microbiol. 25:727-739.
    • (1997) Mol. Microbiol , vol.25 , pp. 727-739
    • Dintilhac, A.1    Alloing, G.2    Granadel, C.3    Claverys, J.-P.4
  • 19
    • 2142655010 scopus 로고    scopus 로고
    • Prevention of pneumococcal disease in mice immunized with conserved surface-accessible proteins
    • Hamel, J., N. Charland, I. Pineau, C. Quellet, S. Rioux, D. Martin, and B. R. Brodeur. 2004. Prevention of pneumococcal disease in mice immunized with conserved surface-accessible proteins. Infect. Immun. 72:2659-2670.
    • (2004) Infect. Immun , vol.72 , pp. 2659-2670
    • Hamel, J.1    Charland, N.2    Pineau, I.3    Quellet, C.4    Rioux, S.5    Martin, D.6    Brodeur, B.R.7
  • 20
    • 0033003470 scopus 로고    scopus 로고
    • Identification of pneumococcal surface protein A as a lactoferrin-binding protein of Streptococcus pneumoniae
    • Hammerschmidt, S., G. Bethe, P. H. Remane, and G. S. Chhatwal. 1999. Identification of pneumococcal surface protein A as a lactoferrin-binding protein of Streptococcus pneumoniae. Infect. Immun. 67:1683-1687.
    • (1999) Infect. Immun , vol.67 , pp. 1683-1687
    • Hammerschmidt, S.1    Bethe, G.2    Remane, P.H.3    Chhatwal, G.S.4
  • 21
    • 0030968621 scopus 로고    scopus 로고
    • SpsA, a novel pneumococcal surface protein with specific binding to secretory immunoglobulin A and secretory component
    • Hammerschmidt, S., S. R. Talay, P. Brandtzaeg, and G. S. Chhatwal. 1997. SpsA, a novel pneumococcal surface protein with specific binding to secretory immunoglobulin A and secretory component. Mol. Microbiol. 25:1113-1124.
    • (1997) Mol. Microbiol , vol.25 , pp. 1113-1124
    • Hammerschmidt, S.1    Talay, S.R.2    Brandtzaeg, P.3    Chhatwal, G.S.4
  • 22
    • 12944326295 scopus 로고    scopus 로고
    • Epidemiological differences among pneumococcal serotypes
    • Hausdorff, W. P., D. R. Feikin, and K. P. Klugman. 2005. Epidemiological differences among pneumococcal serotypes. Lancet Infect. Dis. 5:83-93.
    • (2005) Lancet Infect. Dis , vol.5 , pp. 83-93
    • Hausdorff, W.P.1    Feikin, D.R.2    Klugman, K.P.3
  • 23
    • 0036047758 scopus 로고    scopus 로고
    • Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors
    • Hava, D., and A. Camilli. 2002. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Mol. Microbiol. 45:1389-1406.
    • (2002) Mol. Microbiol , vol.45 , pp. 1389-1406
    • Hava, D.1    Camilli, A.2
  • 24
    • 0033801656 scopus 로고    scopus 로고
    • Diversity of PspA: Mosaic genes and evidence for past recombination in Streptococcus pneumoniae
    • Hollingshead, S. K., R. Becker, and D. E. Briles. 2000. Diversity of PspA: mosaic genes and evidence for past recombination in Streptococcus pneumoniae. Infect. Immun. 68:5889-5900.
    • (2000) Infect. Immun , vol.68 , pp. 5889-5900
    • Hollingshead, S.K.1    Becker, R.2    Briles, D.E.3
  • 25
    • 4644372119 scopus 로고    scopus 로고
    • The ClpP protease of Streptococcus pneumoniae modulates virulence gene expression and protects against fatal pneumococcal challenge
    • Kwon, H. Y., A. D. Ogunniyi, M. H. Choi, S. N. Pyo, D. K. Rhee, and J. C. Paton. 2004. The ClpP protease of Streptococcus pneumoniae modulates virulence gene expression and protects against fatal pneumococcal challenge. Infect. Immun. 72:5646-5653.
    • (2004) Infect. Immun , vol.72 , pp. 5646-5653
    • Kwon, H.Y.1    Ogunniyi, A.D.2    Choi, M.H.3    Pyo, S.N.4    Rhee, D.K.5    Paton, J.C.6
  • 26
    • 32244435397 scopus 로고    scopus 로고
    • Differential expression of key pneumococcal virulence genes in vivo
    • LeMessurier, K. S., A. D. Ogunniyi, and J. C. Paton. 2006. Differential expression of key pneumococcal virulence genes in vivo. Microbiology 152: 305-311.
    • (2006) Microbiology , vol.152 , pp. 305-311
    • LeMessurier, K.S.1    Ogunniyi, A.D.2    Paton, J.C.3
  • 27
    • 30344469401 scopus 로고    scopus 로고
    • Escalation of antimicrobial resistance among Streptococcus pneumoniae: Implications for therapy
    • Lynch, J. P., III, and G. G. Zhanel. 2005. Escalation of antimicrobial resistance among Streptococcus pneumoniae: implications for therapy. Semin. Respir. Crit. Care Med. 26:575-616.
    • (2005) Semin. Respir. Crit. Care Med , vol.26 , pp. 575-616
    • Lynch III, J.P.1    Zhanel, G.G.2
  • 28
    • 8144231515 scopus 로고    scopus 로고
    • Molecular pathogenesis of pneumococcal pneumonia
    • McCullers, J. A., and E. I. Tuomanen. 2001. Molecular pathogenesis of pneumococcal pneumonia. Front. Biosci. 6:D877-D889.
    • (2001) Front. Biosci , vol.6
    • McCullers, J.A.1    Tuomanen, E.I.2
  • 29
    • 0025976331 scopus 로고
    • PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular serotype
    • McDaniel, L. S., J. S. Sheffield, P. Delucchi, and D. E. Briles. 1991. PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular serotype. Infect. Immun. 59:222-228.
    • (1991) Infect. Immun , vol.59 , pp. 222-228
    • McDaniel, L.S.1    Sheffield, J.S.2    Delucchi, P.3    Briles, D.E.4
  • 31
    • 0034114443 scopus 로고    scopus 로고
    • Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae
    • Ogunniyi, A. D., R. L. Folland, D. E. Briles, S. K. Hollingshead, and J. C. Paton. 2000. Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae. Infect. Immun. 68:3028-3033.
    • (2000) Infect. Immun , vol.68 , pp. 3028-3033
    • Ogunniyi, A.D.1    Folland, R.L.2    Briles, D.E.3    Hollingshead, S.K.4    Paton, J.C.5
  • 32
    • 0036067905 scopus 로고    scopus 로고
    • The genes encoding virulence-associated proteins and the capsule of Streptococcus pneumoniae are upregulated and differentially expressed in vivo
    • Ogunniyi, A. D., P. Giammarinaro, and J. C. Paton. 2002. The genes encoding virulence-associated proteins and the capsule of Streptococcus pneumoniae are upregulated and differentially expressed in vivo. Microbiology 148:2045-2053.
    • (2002) Microbiology , vol.148 , pp. 2045-2053
    • Ogunniyi, A.D.1    Giammarinaro, P.2    Paton, J.C.3
  • 33
    • 0034819955 scopus 로고    scopus 로고
    • Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA
    • Ogunniyi, A. D., M. C. Woodrow, J. T. Poolman, and J. C. Paton. 2001. Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA. Infect. Immun. 69:5997-6003.
    • (2001) Infect. Immun , vol.69 , pp. 5997-6003
    • Ogunniyi, A.D.1    Woodrow, M.C.2    Poolman, J.T.3    Paton, J.C.4
  • 34
    • 6944224035 scopus 로고    scopus 로고
    • Tissue-specific contributions of pneumococcal virulence factors to pathogenesis
    • Orihuela, C. J., G. Gao, K. P. Francis, J. Yu, and E. I. Tuomanen. 2004. Tissue-specific contributions of pneumococcal virulence factors to pathogenesis. J. Infect. Dis. 190:1661-1669.
    • (2004) J. Infect. Dis , vol.190 , pp. 1661-1669
    • Orihuela, C.J.1    Gao, G.2    Francis, K.P.3    Yu, J.4    Tuomanen, E.I.5
  • 35
    • 0029917088 scopus 로고    scopus 로고
    • The contribution of pneumolysin to the pathogenicity of Streptococcus pneumoniae
    • Paton, J. C. 1996. The contribution of pneumolysin to the pathogenicity of Streptococcus pneumoniae. Trends Microbiol. 4:103-106.
    • (1996) Trends Microbiol , vol.4 , pp. 103-106
    • Paton, J.C.1
  • 36
    • 33845971049 scopus 로고    scopus 로고
    • New pneumococcal vaccines: Basic science developments
    • E. I. Tuomanen, T. J. Mitchell, D. A. Morrison, and B. G. Spratt ed, ASM Press, Washington, DC
    • Paton, J. C. 2004. New pneumococcal vaccines: basic science developments, p. 382-402. In E. I. Tuomanen, T. J. Mitchell, D. A. Morrison, and B. G. Spratt (ed.), The pneumococcus. ASM Press, Washington, DC.
    • (2004) The pneumococcus , pp. 382-402
    • Paton, J.C.1
  • 37
    • 0030939064 scopus 로고    scopus 로고
    • Molecular analysis of putative pneumococcal virulence proteins
    • Paton, J. C., A. M. Berry, and R. A. Lock. 1997. Molecular analysis of putative pneumococcal virulence proteins. Microb. Drug. Resist. 3:1-10.
    • (1997) Microb. Drug. Resist , vol.3 , pp. 1-10
    • Paton, J.C.1    Berry, A.M.2    Lock, R.A.3
  • 38
    • 0025779030 scopus 로고
    • Purification and immunogenicity of genetically obtained pneumolysin toxoids and their conjugation to Streptococcus pneumoniae type 19F polysaccharide
    • Paton, J. C., R. A. Lock, C.-J. Lee, J. P. Li, A. M. Berry, T. J. Mitchell, P. W. Andrew, D. Hansman, and G. J. Boulnois. 1991. Purification and immunogenicity of genetically obtained pneumolysin toxoids and their conjugation to Streptococcus pneumoniae type 19F polysaccharide. Infect. Immun. 59:2297-2304.
    • (1991) Infect. Immun , vol.59 , pp. 2297-2304
    • Paton, J.C.1    Lock, R.A.2    Lee, C.-J.3    Li, J.P.4    Berry, A.M.5    Mitchell, T.J.6    Andrew, P.W.7    Hansman, D.8    Boulnois, G.J.9
  • 39
    • 0021363204 scopus 로고
    • Activation of human complement by the pneumococcal toxin pneumolysin
    • Paton, J. C., B. Rowan-Kelly, and A. Ferrante. 1984. Activation of human complement by the pneumococcal toxin pneumolysin Infect. Immun. 43: 1085-1087.
    • (1984) Infect. Immun , vol.43 , pp. 1085-1087
    • Paton, J.C.1    Rowan-Kelly, B.2    Ferrante, A.3
  • 40
    • 0032527622 scopus 로고    scopus 로고
    • Pneumococcal trafficking across the blood-brain barrier
    • Ring, A., J. N. Weiser, and E. I. Tuomanen. 1998. Pneumococcal trafficking across the blood-brain barrier. J. Clin. Investig. 102:347-360.
    • (1998) J. Clin. Investig , vol.102 , pp. 347-360
    • Ring, A.1    Weiser, J.N.2    Tuomanen, E.I.3
  • 41
    • 0030983804 scopus 로고    scopus 로고
    • Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae
    • Rosenow, C., P. Ryan, J. N. Weiser, S. Johnson, P. Fontan, A. Ortqvist, and H. R. Masure. 1997. Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae. Mol. Microbiol. 25:819-829.
    • (1997) Mol. Microbiol , vol.25 , pp. 819-829
    • Rosenow, C.1    Ryan, P.2    Weiser, J.N.3    Johnson, S.4    Fontan, P.5    Ortqvist, A.6    Masure, H.R.7
  • 42
    • 4544281498 scopus 로고    scopus 로고
    • PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin
    • Shaper, M., S. K. Hollingshead, W. H. Benjamin, Jr., and D. E. Briles. 2004. PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin. Infect. Immun. 72:5031-5040.
    • (2004) Infect. Immun , vol.72 , pp. 5031-5040
    • Shaper, M.1    Hollingshead, S.K.2    Benjamin Jr., W.H.3    Briles, D.E.4
  • 44
    • 0345283051 scopus 로고    scopus 로고
    • Pneumococcal surface protein A is expressed in vivo, and antibodies to PspA are effective for therapy in a murine model of pneumococcal sepsis
    • Swiatlo, E., J. King, G. S. Nabors, B. Mathews, and D. E. Briles. 2003. Pneumococcal surface protein A is expressed in vivo, and antibodies to PspA are effective for therapy in a murine model of pneumococcal sepsis. Infect. Immun. 71:7149-7153.
    • (2003) Infect. Immun , vol.71 , pp. 7149-7153
    • Swiatlo, E.1    King, J.2    Nabors, G.S.3    Mathews, B.4    Briles, D.E.5
  • 45
    • 0030034830 scopus 로고    scopus 로고
    • Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice
    • Tart, R. C., L. S. McDaniel, B. A. Ralph, and D. E. Briles. 1996. Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice. J. Infect. Dis. 173:380-386.
    • (1996) J. Infect. Dis , vol.173 , pp. 380-386
    • Tart, R.C.1    McDaniel, L.S.2    Ralph, B.A.3    Briles, D.E.4
  • 46
    • 0002752973 scopus 로고
    • Improved media for growing plasmid and cosmid clones
    • Tartof, K. D., and C. A. Hobbs. 1987. Improved media for growing plasmid and cosmid clones. Bethesda Res. Lab. Focus 9:12.
    • (1987) Bethesda Res. Lab. Focus , vol.9 , pp. 12
    • Tartof, K.D.1    Hobbs, C.A.2
  • 47
    • 0032797913 scopus 로고    scopus 로고
    • Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae
    • Tu, A.-H. T., R. L. Fulgham, M. A. McCrory, D. E. Briles, and A. J. Szalai. 1999. Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae. Infect. Immun. 67:4720-4724.
    • (1999) Infect. Immun , vol.67 , pp. 4720-4724
    • Tu, A.-H.T.1    Fulgham, R.L.2    McCrory, M.A.3    Briles, D.E.4    Szalai, A.J.5
  • 48
    • 0028307194 scopus 로고
    • Phase variation in pneumococcal opacity: Relationship between colonial morphology and nasopharyngeal colonization
    • Weiser, J. N., R. Austrian, P. K. Sreenivasan, and H. R. Masure. 1994. Phase variation in pneumococcal opacity: relationship between colonial morphology and nasopharyngeal colonization. Infect. Immun. 62:2582-2589.
    • (1994) Infect. Immun , vol.62 , pp. 2582-2589
    • Weiser, J.N.1    Austrian, R.2    Sreenivasan, P.K.3    Masure, H.R.4
  • 49
    • 0026501145 scopus 로고
    • Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis
    • Yother, J., and D. E. Briles. 1992. Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis. J. Bacteriol. 174:601-609.
    • (1992) J. Bacteriol , vol.174 , pp. 601-609
    • Yother, J.1    Briles, D.E.2
  • 50
    • 22544455943 scopus 로고    scopus 로고
    • Additive inhibition of complement deposition by pneumolysin and PspA facilitates Streptococcus pneumoniae septicemia
    • Yuste, J., M. Botto, J. C. Paton, D. W. Holden, and J. S. Brown. 2005. Additive inhibition of complement deposition by pneumolysin and PspA facilitates Streptococcus pneumoniae septicemia. J. Immunol. 175:1813-1819.
    • (2005) J. Immunol , vol.175 , pp. 1813-1819
    • Yuste, J.1    Botto, M.2    Paton, J.C.3    Holden, D.W.4    Brown, J.S.5
  • 51
    • 0034664821 scopus 로고    scopus 로고
    • The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells
    • Zhang, J. R., K. E. Mostov, M. E. Lamm, M. Nanno, S. Shimida, M. Ohwaki, and E. Tuomanen. 2000. The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells. Cell 102: 827-837.
    • (2000) Cell , vol.102 , pp. 827-837
    • Zhang, J.R.1    Mostov, K.E.2    Lamm, M.E.3    Nanno, M.4    Shimida, S.5    Ohwaki, M.6    Tuomanen, E.7


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