Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal disease

mBio

Volumn 4, Issue 1, 2013, Pages

  Orrskog, Sofia ^a   Rounioja, Samuli ^a   Spadafina, Tiziana ^a   Gallotta, Marilena ^a   Norman, Martin ^a   Hentrich, Karina ^a   Fälker, Stefan ^a   Ygberg Eriksson, Sofia ^a   Hasenberg, Mike ^b   Johansson, Björn ^a   Uotila, Liisa M ^c   Gahmberg, Carl G ^c   Barocchi, Michèle ^d   Gunzer, Matthias ^b   Normark, Staffan ^a   Henriques Normark, Birgitta ^a,e  

^a KAROLINSKA INSTITUTE   (Sweden)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c UNIVERSITY OF HELSINKI   (Finland)

^d NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; ADHESIN RGRA; CD11B ANTIGEN; RECOMBINANT ADHESIN RGRA; RECOMBINANT ADHESIN RGRC; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM PILUS; CELL INTERACTION; CELL MIGRATION; CELL MOTILITY; CELL TRANSPORT; CONTROLLED STUDY; DISEASE ASSOCIATION; HOST PATHOGEN INTERACTION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTEGRIN DOMAIN; INTERNALIZATION; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; OVERALL SURVIVAL; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SEPTICEMIA; STREPTOCOCCUS PNEUMONIAE; SURVIVAL TIME; TIME LAPSE IMAGING;

EID: 84874614983     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00535-12     Document Type: Article

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