The presence of the pilus locus is a clonal property among pneumococcal invasive isolates

BMC Microbiology

Volumn 8, Issue , 2008, Pages

  Aguiar, Sandra I ^a   Serrano, Isa ^a   Pinto, Francisco R ^a   Melo Cristino, José ^a   Ramirez, Mario ^a  

^a UNIVERSITY OF LISBON   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; COTRIMOXAZOLE; ERYTHROMYCIN; PENICILLIN G; TETRACYCLINE; VIRULENCE FACTOR; BACTERIAL PROTEIN; RLRA PROTEIN, STREPTOCOCCUS PNEUMONIAE; TRANSACTIVATOR PROTEIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; BACTERIUM PILUS; CLONOGENESIS; GENE LOCUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PULSED FIELD GEL ELECTROPHORESIS; RLRA GENE; SEROTYPE; STREPTOCOCCUS PNEUMONIAE; ADULT; CLASSIFICATION; FIMBRIA; GENETICS; HUMAN; MICROBIOLOGY; PATHOGENICITY; PORTUGAL; PRESCHOOL CHILD; SEQUENCE ANALYSIS; SEROTYPING; STREPTOCOCCUS INFECTION; VIRULENCE;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS PNEUMONIAE;

ADULT; BACTERIAL PROTEINS; CHILD, PRESCHOOL; ELECTROPHORESIS, GEL, PULSED-FIELD; FIMBRIAE, BACTERIAL; HUMANS; PNEUMOCOCCAL INFECTIONS; PORTUGAL; SEQUENCE ANALYSIS; SEROTYPING; STREPTOCOCCUS PNEUMONIAE; TRANS-ACTIVATORS; VIRULENCE;

EID: 41149167131     PISSN: 14712180     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-8-41     Document Type: Article

References (35)

1. Pili in gram-positive pathogens. JL Telford MA Barocchi I Margarit R Rappuoli G Grandi, Nat Rev Microbiol 2006 4 509 519 10.1038/nrmicro1443 16778837
2. Group A Streptococcus produce pilus-like structures containing protective antigens and Lancefield T antigens. M Mora G Bensi S Capo F Falugi C Zingaretti AG Manetti T Maggi AR Taddei G Grandi JL Telford, Proc Natl Acad Sci U S A 2005 102 15641 15646 16223875 10.1073/pnas.0507808102
3. Genome analysis reveals pili in Group B Streptococcus. P Lauer CD Rinaudo M Soriani I Margarit D Maione R Rosini AR Taddei M Mora R Rappuoli G Grandi JL Telford, Science 2005 309 105 10.1126/science.1111563 15994549
4. A pneumococcal pilus influences virulence and host inflammatory responses. MA Barocchi J Ries X Zogaj C Hemsley B Albiger A Kanth S Dahlberg J Fernebro M Moschioni V Masignani K Hultenby AR Taddei K Beiter F Wartha A von Euler A Covacci DW Holden S Normark R Rappuoli B Henriques-Normark, Proc Natl Acad Sci U S A 2006 103 2857 2862 16481624 10.1073/pnas.0511017103
5. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. DL Hava A Camilli, Mol Microbiol 2002 45 1389 1406 12207705
6. Transcriptional regulation in the Streptococcus pneumoniae rlrA pathogenicity islet by RlrA. DL Hava CJ Hemsley A Camilli, J Bacteriol 2003 185 413 421 12511486 10.1128/JB.185.2.413-421.2003
7. RrgA and RrgB are components of a multisubunit pilus encoded by the Streptococcus pneumoniae rlrA pathogenicity islet. J LeMieux DL Hava A Basset A Camilli, Infect Immun 2006 74 2453 2456 16552078 10.1128/IAI.74.4.2453-2456.2006
8. MgrA, an orthologue of Mga, Acts as a transcriptional repressor of the genes within the rlrA pathogenicity islet in Streptococcus pneumoniae. C Hemsley E Joyce DL Hava A Kawale A Camilli, J Bacteriol 2003 185 6640 6647 14594838 10.1128/JB.185.22.6640-6647.2003
9. Streptococcus pneumoniae pilus subunits protect mice against lethal challenge. C Gianfaldoni S Censini M Hilleringmann M Moschioni C Facciotti W Pansegrau V Masignani A Covacci R Rappuoli MA Barocchi P Ruggiero, Infect Immun 2007 75 1059 1062 17145945 10.1128/IAI.01400-06
10. Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. H Tettelin KE Nelson IT Paulsen JA Eisen TD Read S Peterson J Heidelberg RT DeBoy DH Haft RJ Dodson AS Durkin M Gwinn JF Kolonay WC Nelson JD Peterson LA Umayam O White SL Salzberg MR Lewis D Radune E Holtzapple H Khouri AM Wolf TR Utterback CL Hansen LA McDonald TV Feldblyum S Angiuoli T Dickinson EK Hickey IE Holt BJ Loftus F Yang HO Smith JC Venter BA Dougherty DA Morrison SK Hollingshead CM Fraser, Science 2001 293 498 506 10.1126/science.1061217 11463916
11. The role of Streptococcus pneumoniae sortase A in colonisation and pathogenesis. GK Paterson TJ Mitchell, Microbes Infect 2006 8 145 153 10.1016/j.micinf.2005.06.009 16182588
12. Association of the pneumococcal pilus with certain capsular serotypes but not with increased virulence. A Basset K Trzcinski C Hermos KL O'Brien R Reid M Santosham AJ McAdam M Lipsitch R Malley, J Clin Microbiol 2007 45 1684 1689 17392439 10.1128/JCM.00265-07
13. Characterization of the genetic lineages responsible for pneumococcal invasive disease in Portugal. I Serrano J Melo-Cristino JA Carriço M Ramirez, J Clin Microbiol 2005 43 1706 1715 15814989 10.1128/JCM.43.4.1706-1715. 2005
14. Displaying the relatedness among isolates of bacterial species - the eBURST approach. BG Spratt WP Hanage B Li DM Aanensen EJ Feil, FEMS Microbiol Lett 2004 241 129 134 10.1016/j.femsle.2004.11.015 15598523
15. Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. L McGee L McDougal J Zhou BG Spratt FC Tenover R George R Hakenbeck W Hryniewicz JC Lefevre A Tomasz KP Klugman, J Clin Microbiol 2001 39 2565 2571 11427569 10.1128/JCM.39.7.2565-2571.2001
16. The PMEN clone list. http://www.sph.emory.edu/PMEN/pmen_clone_collection. html
17. Heterogeneity of pneumococcal phase variants in invasive human infections. I Serrano J Melo-Cristino M Ramirez, BMC Microbiol 2006 6 67 16872486 10.1186/1471-2180-6-67
18. Clonal relationships between invasive and carriage Streptococcus pneumoniae and serotype- and clone-specific differences in invasive disease potential. AB Brueggemann DT Griffiths E Meats T Peto DW Crook BG Spratt, J Infect Dis 2003 187 1424 1432 10.1086/374624 12717624
19. Clonal success of piliated penicillin nonsusceptible pneumococci. K Sjöström C Blomberg J Fernebro J Dagerhamn E Morfeldt MA Barocchi S Browall M Moschioni M Andersson F Henriques B Albiger R Rappuoli S Normark B Henriques-Normark, Proc Natl Acad Sci U S A 2007 104 12907 12912 17644611 10.1073/pnas.0705589104
20. Chromosomal rearrangements. GM Weinstock JR Lupski, Bacterial genomes - physical structure and analysis Dordrecht, The Netherlands, Kluwer Academic Publishers, Bruijn FJ, Lupski JR and Weinstock GM, 1999 112 118
21. Invasive Streptococcus pneumoniae from Portugal: implications for vaccination and antimicrobial therapy. I Serrano M Ramirez The Portuguese Surveillance Group for the Study of Respiratory Pathogens J Melo-Cristino, Clin Microbiol Infect 2004 10 652 656 10.1111/j.1469-0691.2004.00869.x 15214879
22. Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. CG Whitney MM Farley J Hadler LH Harrison NM Bennett R Lynfield A Reingold PR Cieslak T Pilishvili D Jackson RR Facklam JH Jorgensen A Schuchat, N Engl J Med 2003 348 1737 1746 10.1056/NEJMoa022823 12724479
23. Changes in pneumococcal invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine. SI Aguiar I Serrano FR Pinto J Melo-Cristino M Ramirez the Portuguese Surveillance Group for the Study of Respiratory Pathogens, Submitted
24. Clonal distribution of invasive pneumococcal isolates from children and selected adults in the United States prior to 7-valent conjugate vaccine introduction. RE Gertz Jr. MC McEllistrem DJ Boxrud Z Li V Sakota TA Thompson RR Facklam JM Besser LH Harrison CG Whitney B Beall, J Clin Microbiol 2003 41 4194 4216 12958247 10.1128/JCM.41.9.4194-4216.2003
25. Genome of the bacterium Streptococcus pneumoniae strain R6. J Hoskins WE Alborn Jr. J Arnold LC Blaszczak S Burgett BS DeHoff ST Estrem L Fritz DJ Fu W Fuller C Geringer R Gilmour JS Glass H Khoja AR Kraft RE Lagace DJ LeBlanc LN Lee EJ Lefkowitz J Lu P Matsushima SM McAhren M McHenney K McLeaster CW Mundy TI Nicas FH Norris M O'Gara RB Peery GT Robertson P Rockey PM Sun ME Winkler Y Yang M Young-Bellido G Zhao CA Zook RH Baltz SR Jaskunas PR Rosteck Jr. PL Skatrud JI Glass, J Bacteriol 2001 183 5709 5717 11544234 10.1128/JB.183.19. 5709-5717.2001
26. Current protocols in molecular biology. FM Ausubel R Brent RE Kingston DD Moore JG Seidman JA Smith, Current Protocols New York, Published by Greene Pub. Associates and Wiley-Interscience : J. Wiley, Chanda VB, 1999
27. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0. K Tamura J Dudley M Nei S Kumar, Mol Biol Evol 2007 24 1596 1599 10.1093/molbev/msm092 17488738
28. GATA: a graphic alignment tool for comparative sequence analysis. DA Nix MB Eisen, BMC Bioinformatics 2005 6 9 15655071 10.1186/1471-2105-6-9
29. Illustration of a common framework for relating multiple typing methods by application to macrolide-resistant Streptococcus pyogenes. JA Carriço C Silva-Costa J Melo-Cristino FR Pinto H de Lencastre JS Almeida M Ramirez, J Clin Microbiol 2006 44 2524 2532 16825375 10.1128/JCM.02536-05
30. Practical statistics for medical research. DG Altman, Boca Raton, Fla., Chapman & Hall/CRC 1999 xii, 611 p.
31. Confidence limits for a cross-product ratio. RA Fisher, Australian Journal of Statistics 1962 4 41 10.1111/j.1467-842X.1962.tb00285.x
32. Controlling the false discovery rate - a practical and powerful approch to multiple testing. Y Benjamini Y Hochberg, J R Stat Soc Ser B Statistical Methodology 1995 57 289 300
33. Categorical data analysis. A Agresti, Wiley series in probability and mathematical statistics Applied probability and statistics New York, Wiley 1990 xv, 558 p.
34. Comparing partitions website. http://www.comparingpartitions.info
35. EpiTools: R package for Epidemiologic Data and Graphics. T Aragon, 0.4-8 2007 http://www.epitools.net