Enhancement of nystatin production by redirecting precursor fluxes after disruption of the tetramycin gene from Streptomyces ahygroscopicus

Microbiological Research

Volumn 169, Issue 7-8, 2014, Pages 602-608

  Ren, Jun ^a   Cui, Yuqiong ^a   Zhang, Fan ^a   Cui, Hao ^a   Ni, Xianpu ^a   Chen, Fei ^b   Li, Li ^b   Xia, Huanzhang ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b Liaoning Scientific Academy of Microbiology   (China)

Author keywords

Coenzyme A precursors; Gene disruption; Nystatin A1; Polyene macrolide antibiotics; Tetramycin

Indexed keywords

ANTIBIOTICS; ATOMS; BACTERIA; ORGANIC COMPOUNDS;

COENZYME A; GENE DISRUPTIONS; NYSTATIN A1; POLYENE MACROLIDE; TETRAMYCIN;

GENES;

ENZYME ACTIVITY; FUNGAL DISEASE; GENE EXPRESSION; METABOLISM; MUTATION;

STREPTOMYCES;

ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; MACROLIDE; NYSTATIN; POLYKETIDE SYNTHASE; TETRAMYCIN;

BIOSYNTHESIS; GENETICS; METABOLISM; MULTIGENE FAMILY; STREPTOMYCES; UPREGULATION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BIOSYNTHETIC PATHWAYS; MACROLIDES; MULTIGENE FAMILY; NYSTATIN; POLYKETIDE SYNTHASES; STREPTOMYCES; UP-REGULATION;

EID: 84899930722     PISSN: 09445013     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micres.2013.09.017     Document Type: Article

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