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Volumn 36, Issue 10, 2009, Pages 1257-1265

Exploration of geosmin synthase from streptomyces peucetius ATCC 27952 by deletion of doxorubicin biosynthetic gene cluster

Author keywords

Doxorubicin; Geosmin; Overexpression; Sesquiterpene synthase; Streptomyces peucetius

Indexed keywords

AMINO ACID DERIVATIVE; DOXORUBICIN; GEOSMIN; POLYKETIDE SYNTHASE; SYNTHETASE;

EID: 70349600327     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-009-0605-0     Document Type: Article
Times cited : (17)

References (32)
  • 1
    • 0037452696 scopus 로고    scopus 로고
    • Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis
    • DOI 10.1073/pnas.0337625100
    • DE Cane RM Watt 2003 Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis Proc Natl Acad Sci USA 100 1547 1551 12556563 10.1073/pnas. 0337625100 1:CAS:528:DC%2BD3sXhsFGktrc%3D (Pubitemid 36254484)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.4 , pp. 1547-1551
    • Cane, D.E.1    Watt, R.M.2
  • 2
    • 19644376986 scopus 로고    scopus 로고
    • Studies on terpenoids produced by actinomycetes. Isolation and structural elucidation of antioxidative agents, naphterpins B and C
    • 15981415 10.1038/ja.2005.33 1:CAS:528:DC%2BD2MXjvFalsrY%3D
    • H Takagi K Motohashi T Miyamoto K Shin-ya K Furihata H Seto 2005 Studies on terpenoids produced by actinomycetes. Isolation and structural elucidation of antioxidative agents, naphterpins B and C J Antibiot 58 275 278 15981415 10.1038/ja.2005.33 1:CAS:528:DC%2BD2MXjvFalsrY%3D
    • (2005) J Antibiot , vol.58 , pp. 275-278
    • Takagi, H.1    Motohashi, K.2    Miyamoto, T.3    Shin-Ya, K.4    Furihata, K.5    Seto, H.6
  • 3
    • 33646052859 scopus 로고    scopus 로고
    • Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tü6071: Analysis of the gene cluster and generation of derivatives
    • 16632249 10.1016/j.chembiol.2006.01.011
    • C Dürr HJ Schnell A Luzhetskyy R Murillo M Weber K Welzel A Vente A Bechthold 2006 Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tü6071: analysis of the gene cluster and generation of derivatives Chem Biol 13 365 377 16632249 10.1016/j.chembiol.2006.01.011
    • (2006) Chem Biol , vol.13 , pp. 365-377
    • Dürr, C.1    Schnell, H.J.2    Luzhetskyy, A.3    Murillo, R.4    Weber, M.5    Welzel, K.6    Vente, A.7    Bechthold, A.8
  • 4
    • 33646591928 scopus 로고    scopus 로고
    • A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilis
    • DOI 10.1021/bi060419n
    • CN Tetzlaff Z You DE Cane S Takamatsu S Omura H Ikeda 2006 A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilis Biochemistry 45 6179 6186 16681390 10.1021/bi060419n 1:CAS:528:DC%2BD28XjsFKitLY%3D (Pubitemid 43727110)
    • (2006) Biochemistry , vol.45 , Issue.19 , pp. 6179-6186
    • Tetzlaff, C.N.1    You, Z.2    Cane, D.E.3    Takamatsu, S.4    Omura, S.5    Ikeda, H.6
  • 5
    • 37249061371 scopus 로고    scopus 로고
    • Studies on terpenoids produced by actinomycetes: Oxaloterpins A, B, C, D, and E, diterpenes from Streptomyces sp. KO-3988
    • DOI 10.1021/np070326m
    • K Motohashi R Ueno M Sue K Furihata T Matsumoto T Dairi S Omura H Seto 2007 Studies on terpenoids produced by actinomycetes: oxaloterpins A, B, C, D, and E, diterpenes from Streptomyces sp. KO-3988 J Nat Prod 70 1712 1717 17970596 10.1021/np070326m 1:CAS:528:DC%2BD2sXht1Grt7bJ (Pubitemid 350275525)
    • (2007) Journal of Natural Products , vol.70 , Issue.11 , pp. 1712-1717
    • Motohashi, K.1    Ueno, R.2    Sue, M.3    Furihata, K.4    Matsumoto, T.5    Dairi, T.6    Omura, S.7    Seto, H.8
  • 7
    • 15544389776 scopus 로고    scopus 로고
    • Studies on biosynthetic genes and enzymes of isoprenoids produced by actinomycetes
    • T Dairi 2005 Studies on biosynthetic genes and enzymes of isoprenoids produced by actinomycetes J Antibiot 58 227 243 15981409 10.1038/ja.2005.27 1:CAS:528:DC%2BD2MXjvFalsrw%3D (Pubitemid 40740598)
    • (2005) Journal of Antibiotics , vol.58 , Issue.4 , pp. 227-243
    • Dairi, T.1
  • 8
    • 65349089699 scopus 로고    scopus 로고
    • Genes and enzymes involved in bacterial isoprenoid biosynthesis
    • 19318289 10.1016/j.cbpa.2009.02.029 1:CAS:528:DC%2BD1MXlsVektrY%3D
    • M Daum S Herrmann B Wilkinson A Bechthold 2009 Genes and enzymes involved in bacterial isoprenoid biosynthesis Curr Opin Chem Biol 13 180 188 19318289 10.1016/j.cbpa.2009.02.029 1:CAS:528:DC%2BD1MXlsVektrY%3D
    • (2009) Curr Opin Chem Biol , vol.13 , pp. 180-188
    • Daum, M.1    Herrmann, S.2    Wilkinson, B.3    Bechthold, A.4
  • 9
    • 0037313208 scopus 로고    scopus 로고
    • Mevalonate-independent methylerythritol phosphate pathway for isoprenoid biosynthesis. Elucidation and distribution
    • 10.1351/pac200375020375 1:CAS:528:DC%2BD3sXjt1WgtL4%3D
    • M Rohmer 2003 Mevalonate-independent methylerythritol phosphate pathway for isoprenoid biosynthesis. Elucidation and distribution Pure Appl Chem 75 375 387 10.1351/pac200375020375 1:CAS:528:DC%2BD3sXjt1WgtL4%3D
    • (2003) Pure Appl Chem , vol.75 , pp. 375-387
    • Rohmer, M.1
  • 10
    • 0032544054 scopus 로고    scopus 로고
    • A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis
    • DOI 10.1073/pnas.95.17.9879
    • S Takahashi T Kuzuyama H Watanabe H Seto 1998 A 1-deoxy-d-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-d-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis Proc Natl Acad Sci USA 95 9879 9884 9707569 10.1073/pnas.95.17.9879 1:CAS:528:DyaK1cXlsFSrtbw%3D (Pubitemid 28415263)
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.17 , pp. 9879-9884
    • Takahashi, S.1    Kuzuyama, T.2    Watanabe, H.3    Seto, H.4
  • 11
    • 33644942482 scopus 로고    scopus 로고
    • Genetic improvement of processes yielding microbial products
    • 16472304 10.1111/j.1574-6976.2005.00009.x 1:CAS:528:DC%2BD28Xit1Sjsrc%3D
    • JL Adrio AL Demain 2006 Genetic improvement of processes yielding microbial products FEMS Microbiol Rev 30 187 214 16472304 10.1111/j.1574-6976. 2005.00009.x 1:CAS:528:DC%2BD28Xit1Sjsrc%3D
    • (2006) FEMS Microbiol Rev , vol.30 , pp. 187-214
    • Adrio, J.L.1    Demain, A.L.2
  • 12
    • 0032082974 scopus 로고    scopus 로고
    • The role of metabolic engineering in the production of secondary metabolites
    • 10066494 10.1016/S1369-5274(98)80037-4 1:CAS:528:DyaK1cXkslantbs%3D
    • J Nielsen 1998 The role of metabolic engineering in the production of secondary metabolites Curr Opin Microbiol 1 330 336 10066494 10.1016/S1369-5274(98)80037-4 1:CAS:528:DyaK1cXkslantbs%3D
    • (1998) Curr Opin Microbiol , vol.1 , pp. 330-336
    • Nielsen, J.1
  • 13
    • 0013815605 scopus 로고
    • Geosmin, an earthy-smelling substance isolated from actinomycetes
    • 5866039 1:CAS:528:DyaF2MXkvFSnsLY%3D
    • NN Gerber HA Lechevalier 1965 Geosmin, an earthy-smelling substance isolated from actinomycetes Appl Microbiol 13 935 938 5866039 1:CAS:528:DyaF2MXkvFSnsLY%3D
    • (1965) Appl Microbiol , vol.13 , pp. 935-938
    • Gerber, N.N.1    Lechevalier, H.A.2
  • 14
    • 0018539410 scopus 로고
    • Volatile substances from actinomycetes: Their role in the odor pollution of water
    • 396107 10.3109/10408417909082014 1:CAS:528:DyaL3cXptVCrtA%3D%3D
    • NN Gerber 1979 Volatile substances from actinomycetes: their role in the odor pollution of water CRC Crit Rev Microbiol 7 191 214 396107 10.3109/10408417909082014 1:CAS:528:DyaL3cXptVCrtA%3D%3D
    • (1979) CRC Crit Rev Microbiol , vol.7 , pp. 191-214
    • Gerber, N.N.1
  • 15
  • 16
    • 33749474044 scopus 로고    scopus 로고
    • Geosmin biosynthesis in Streptomyces avermitilis: Molecular cloning, expression, and mechanistic study of the germacradienol/geosmin synthase
    • 17080683 10.1038/ja.2006.66 1:CAS:528:DC%2BD28XpvVGitb0%3D
    • DE Cane X He S Kobayashi S Omura H Ikeda 2006 Geosmin biosynthesis in Streptomyces avermitilis: molecular cloning, expression, and mechanistic study of the germacradienol/geosmin synthase J Antibiot 59 471 479 17080683 10.1038/ja.2006.66 1:CAS:528:DC%2BD28XpvVGitb0%3D
    • (2006) J Antibiot , vol.59 , pp. 471-479
    • Cane, D.E.1    He, X.2    Kobayashi, S.3    Omura, S.4    Ikeda, H.5
  • 17
    • 40149102723 scopus 로고    scopus 로고
    • Geosmin biosynthesis. Mechanism of the fragmentation-rearrangement in the conversion of germacradienol to geosmin
    • 18095692 10.1021/ja077792i 1:CAS:528:DC%2BD2sXhsVCrsLfI
    • J Jiang X He DE Cane 2008 Geosmin biosynthesis. Mechanism of the fragmentation-rearrangement in the conversion of germacradienol to geosmin J Am Chem Soc 130 428 429 18095692 10.1021/ja077792i 1:CAS:528:DC%2BD2sXhsVCrsLfI
    • (2008) J Am Chem Soc , vol.130 , pp. 428-429
    • Jiang, J.1    He, X.2    Cane, D.E.3
  • 18
    • 50249173268 scopus 로고    scopus 로고
    • Cloning and functional characterization of the germacradienol synthase (spterp13) from Streptomyces peucetius ATCC 27952
    • 18667848 1:CAS:528:DC%2BD1MXotFSms7s%3D
    • GP Ghimire TJ Oh HC Lee BG Kim JK Sohng 2008 Cloning and functional characterization of the germacradienol synthase (spterp13) from Streptomyces peucetius ATCC 27952 J Microbiol Biotechnol 18 1216 1220 18667848 1:CAS:528:DC%2BD1MXotFSms7s%3D
    • (2008) J Microbiol Biotechnol , vol.18 , pp. 1216-1220
    • Ghimire, G.P.1    Oh, T.J.2    Lee, H.C.3    Kim, B.G.4    Sohng, J.K.5
  • 19
    • 0026645203 scopus 로고
    • Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp
    • 1628843 10.1016/0378-1119(92)90627-2 1:CAS:528:DyaK38XltVGgt74%3D
    • M Bierman R Logan K O'Brien ET Seno RN Rao BE Schoner 1992 Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp Gene 116 43 49 1628843 10.1016/0378-1119(92)90627-2 1:CAS:528:DyaK38XltVGgt74%3D
    • (1992) Gene , vol.116 , pp. 43-49
    • Bierman, M.1    Logan, R.2    O'Brien, K.3    Seno, E.T.4    Rao, R.N.5    Schoner, B.E.6
  • 20
    • 0026667294 scopus 로고
    • Complex organisation of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase
    • 1612425 10.1016/0378-1119(92)90549-5 1:CAS:528:DyaK38XlsVCmurc%3D
    • DJ MacNeil JL Occi KM Gewain T MacNeil PH Gibbons CL Rudy SJ Danis 1992 Complex organisation of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase Gene 115 119 125 1612425 10.1016/0378-1119(92) 90549-5 1:CAS:528:DyaK38XlsVCmurc%3D
    • (1992) Gene , vol.115 , pp. 119-125
    • MacNeil, D.J.1    Occi, J.L.2    Gewain, K.M.3    MacNeil, T.4    Gibbons, P.H.5    Rudy, C.L.6    Danis, S.J.7
  • 23
    • 34548635755 scopus 로고    scopus 로고
    • Analysis of intracellular short organic acid-coenzyme a esters from actinomycetes using liquid chromatography-electrospray ionization-mass spectrometry
    • DOI 10.1002/jms.1240
    • JW Park WS Jung SR Park BC Park YJ Yoon 2007 Analysis of intracellular short organic acid-coenzyme A esters from actinomycetes using liquid chromatography-electrospray ionization-mass spectrometry J Mass Spectrom 42 1136 1147 17565713 10.1002/jms.1240 1:CAS:528:DC%2BD2sXhtVyktLzM (Pubitemid 47401838)
    • (2007) Journal of Mass Spectrometry , vol.42 , Issue.9 , pp. 1136-1147
    • Je, W.P.1    Won, S.J.2    Sung, R.P.3    Byoung, C.P.4    Yeo, J.Y.5
  • 24
    • 2442492158 scopus 로고    scopus 로고
    • Neocarzinostatin naphthoate synthase: An unique iterative type I PKS from neocarzinostatin producer Streptomyces carzinostaticus
    • DOI 10.1016/j.febslet.2004.04.033, PII S0014579304004983
    • B Sthapit T-J Oh R Lamichhane KK Liou HC Lee CG Kim JK Sohng 2004 Neocarzinostatin naphthoate synthase: an unique iterative type I PKS from neocarzinostatin producer Streptomyces carzinostaticus FEBS Lett 566 201 206 15147895 10.1016/j.febslet.2004.04.033 1:CAS:528:DC%2BD2cXktVOksLs%3D (Pubitemid 38625958)
    • (2004) FEBS Letters , vol.566 , Issue.1-3 , pp. 201-206
    • Sthapit, B.1    Oh, T.-J.2    Lamichhane, R.3    Liou, K.4    Lee, H.C.5    Kim, C.-G.6    Sohng, J.K.7
  • 25
    • 0028555349 scopus 로고
    • Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase
    • 7828855 10.1016/0378-1119(94)90625-4 1:CAS:528:DyaK2MXjtFSht7g%3D
    • A Grimm K Madduri A Ali CR Hutchinson 1994 Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase Gene 151 1 10 7828855 10.1016/0378-1119(94)90625-4 1:CAS:528:DyaK2MXjtFSht7g%3D
    • (1994) Gene , vol.151 , pp. 1-10
    • Grimm, A.1    Madduri, K.2    Ali, A.3    Hutchinson, C.R.4
  • 26
    • 0032766245 scopus 로고    scopus 로고
    • The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide
    • 10419974 1:CAS:528:DyaK1MXkvFCiur4%3D
    • W Bao PJ Sheldon E Wendt-Pienkowski CR Hutchinson 1999 The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide J Bacteriol 181 4690 4695 10419974 1:CAS:528: DyaK1MXkvFCiur4%3D
    • (1999) J Bacteriol , vol.181 , pp. 4690-4695
    • Bao, W.1    Sheldon, P.J.2    Wendt-Pienkowski, E.3    Hutchinson, C.R.4
  • 27
    • 0030998697 scopus 로고    scopus 로고
    • Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria
    • 9023936 1:CAS:528:DyaK2sXhtVKkuro%3D
    • S Chohnan H Furukawa T Fujio H Nishihara Y Takamura 1997 Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria Appl Environ Microbiol 63 553 560 9023936 1:CAS:528:DyaK2sXhtVKkuro%3D
    • (1997) Appl Environ Microbiol , vol.63 , pp. 553-560
    • Chohnan, S.1    Furukawa, H.2    Fujio, T.3    Nishihara, H.4    Takamura, Y.5
  • 28
    • 2342590693 scopus 로고    scopus 로고
    • Cofactor engineering of intracellular CoA/acetyl-CoA and its effect on metabolic flux redistribution in Escherichia coli
    • DOI 10.1016/j.ymben.2004.02.001
    • RV Vadalia GN Bennett KY San 2004 Cofactor engineering of intracellular CoA/acetyl-CoA and its effect on metabolic flux redistribution in Escherichia coli Metab Eng 6 133 139 10.1016/j.ymben.2004.02.001 (Pubitemid 38601066)
    • (2004) Metabolic Engineering , vol.6 , Issue.2 , pp. 133-139
    • Vadali, R.V.1    Bennett, G.N.2    San, K.-Y.3
  • 29
    • 0027389215 scopus 로고
    • Growth rate regulation of Escherichia coli acetyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis
    • 7678242 1:CAS:528:DyaK3sXhtFyjtb8%3D
    • S-J Li JE Cronan Jr 1993 Growth rate regulation of Escherichia coli acetyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis J Bacteriol 175 332 340 7678242 1:CAS:528:DyaK3sXhtFyjtb8%3D
    • (1993) J Bacteriol , vol.175 , pp. 332-340
    • Li, S.-J.1    Cronan Jr, J.E.2
  • 30
    • 33750969392 scopus 로고    scopus 로고
    • Engineering of primary carbohydrate metabolism for increased production of actinorhodin in Streptomyces codicolor
    • DOI 10.1128/AEM.01308-06
    • YG Ryu MJ Butler KF Chater KJ Lee 2006 Engineering of primary carbohydrate metabolism for increased production of actinorhodin in Streptomyces coelicolor Appl Environ Microbiol 72 7132 7139 16950896 10.1128/AEM.01308-06 1:CAS:528:DC%2BD28Xht1Gksr%2FI (Pubitemid 44748426)
    • (2006) Applied and Environmental Microbiology , vol.72 , Issue.11 , pp. 7132-7139
    • Ryu, Y.-G.1    Butler, M.J.2    Chater, K.F.3    Lee, K.J.4
  • 31
    • 22144470117 scopus 로고    scopus 로고
    • An unexpected role for the putative 4′-phosphopantetheinyl transferase-encoding gene nysF in the regulation of nystatin biosynthesis in Streptomyces noursei ATCC 11455
    • DOI 10.1016/j.femsle.2005.05.052, PII S0378109705003472
    • O Volokhan H Sletta ON Sekurova TE Ellingsen SB Zotchev 2005 An unexpected role for the putative 4?-phosphopantetheinyl transferase-encoding gene nysF in the regulation of nystatin biosynthesis in Streptomyces noursei ATCC 11455 FEMS Microbiol Lett 249 57 64 15990252 10.1016/j.femsle.2005.05.052 1:CAS:528:DC%2BD2MXmsVCktL0%3D (Pubitemid 40981880)
    • (2005) FEMS Microbiology Letters , vol.249 , Issue.1 , pp. 57-64
    • Volokhan, O.1    Sletta, H.2    Sekurova, O.N.3    Ellingsen, T.E.4    Zotchev, S.B.5
  • 32
    • 0036175076 scopus 로고    scopus 로고
    • 'Streptomyces nanchangensis', a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters
    • 11832500 1:CAS:528:DC%2BD38XhsFSmt70%3D
    • Y Sun X Zhou J Liu K Bao G Zhang G Tu T Kieser Z Deng 2002 'Streptomyces nanchangensis', a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters Microbiology 148 361 371 11832500 1:CAS:528: DC%2BD38XhsFSmt70%3D
    • (2002) Microbiology , vol.148 , pp. 361-371
    • Sun, Y.1    Zhou, X.2    Liu, J.3    Bao, K.4    Zhang, G.5    Tu, G.6    Kieser, T.7    Deng, Z.8


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