Stimulation of mitochondrial embryo metabolism by dichloroacetic acid in an aged mouse model improves embryo development and viability

Fertility and Sterility

Volumn 101, Issue 5, 2014, Pages

  McPherson, Nicole O ^a   Zander Fox, Deirdre ^a,b   Lane, Michelle ^a,b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b Repromed   (Australia)

Author keywords

Embryo development; IVF; mitochondrial medicine

Indexed keywords

ADENOSINE TRIPHOSPHATE; DICHLOROACETIC ACID; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLASTOCYST; CELL COUNT; CELL PH; CITRIC ACID CYCLE; CONTROLLED STUDY; DNA DAMAGE; ECTODERM; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; EMBRYO VIABILITY; FEMALE; FETUS DEVELOPMENT; FETUS WEIGHT; HOMEOSTASIS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INNER CELL MASS; MATING; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NIDATION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PLACENTA WEIGHT; PREGNANCY OUTCOME; PRIORITY JOURNAL; SUPEROVULATION; ZYGOTE; AGING; ANIMAL; CELL CULTURE; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PHYSIOLOGY; PILOT STUDY; PREGNANCY; PROCEDURES;

AGING; ANIMALS; CELLS, CULTURED; DICHLOROACETIC ACID; EMBRYO TRANSFER; EMBRYONIC DEVELOPMENT; FEMALE; MICE; MITOCHONDRIA; MODELS, ANIMAL; PILOT PROJECTS; PREGNANCY;

EID: 84899930267     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.12.057     Document Type: Article

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