Stability and cellular uptake of lutein-loaded emulsions

Journal of Functional Foods

Volumn 8, Issue 1, 2014, Pages 118-127

  Frede, Katja ^a,b   Henze, Andrea ^a   Khalil, Mahmoud ^a   Baldermann, Susanne ^a,b   Schweigert, Florian J ^a   Rawel, Harshadrai ^a  

^a UNIVERSITY OF POTSDAM   (Germany)

^b Inst Veg Orn Crops G Erfurt   (Germany)

Author keywords

Bioavailability; Emulsion; Lutein; Stability; Whey protein

Indexed keywords

EID: 84899929852     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2014.03.011     Document Type: Article

References (27)

1. Aman R., Schieber A., Carle R. Effects of heating and illumination on trans-cis isomerization and degradation of ß-carotene and lutein in isolated spinach chloroplasts. Journal of Agricultural and Food Chemistry 2005, 53:9512-9518.
2. Attaallah W., Yilmaz A.M., Erdoǧan N., Yalçin A.S., Aktan A.O. Whey protein versus whey protein hydrolyzate for the protection of azoxymethane and dextran sodium sulfate induced colonic tumors in rats. Pathology Oncology Research 2012, 18:817-822.
3. Baruchel S., Viau G. In vitro selective modulation of cellular glutathione by a humanized native milk protein isolate in normal cells and rat mammary carcinoma model. Anticancer Research 1996, 16:1095-1099.
4. Benke K.E., Sharma S., Benke K.K. Assessment of the AREDS2 double-blind clinical trial on nutrients for risk mitigation of age-related macular degeneration. The Journal of the Australasian College of Nutritional and Environmental Medicine 2013, 32:8-11.
5. Briviba K., Schnäbele K., Schwertle E., Blockhaus M., Rechkemmer G. Beta-carotene inhibits growth of human colon carcinoma cells in vitro by induction of apoptosis. Biological Chemistry 2001, 382:1663-1668.
6. Cazzonelli C.I. Carotenoids in nature: insights from plants and beyond. Functional Plant Biology 2011, 38:833-847.
7. Dacaranhe C.D., Terao J. A unique antioxidant activity of phosphatidylserine on iron-induced lipid peroxidation of phospholipid bilayers. Lipids 2001, 36:1105-1110.
8. Dawczynski J., Jentsch S., Schweitzer D., Hammer M., Lang G.E., Strobel J. Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study. Graefe's Archive for Clinical and Experimental Ophthalmology 2013, 251:2711-2723.
9. Elias R.J., Bridgewater J.D., Vachet R.W., Waraho T., McClements D.J., Decker E.A. Antioxidant mechanisms of enzymatic hydrolysates of ß-lactoglobulin in food lipid dispersions. Journal of Agricultural and Food Chemistry 2006, 54:9565-9572.
10. Elias R.J., McClements D.J., Decker E.A. Antioxidant activity of cysteine, tryptophan, and methionine residues in continuous phase ß-lactoglobulin in oil-in-water emulsions. Journal of Agricultural and Food Chemistry 2005, 53:10248-10253.
11. Habib H.M., Ibrahim W.H., Schneider-Stock R., Hassan H.M. Camel milk lactoferrin reduces the proliferation of colorectal cancer cells and exerts antioxidant and DNA damage inhibitory activities. Food Chemistry 2013, 141:148-152.
12. Humberstone A.J., Charman W.N. Lipid-based vehicles for the oral delivery of poorly water soluble drugs. Advanced Drug Delivery Reviews 1997, 25:103-128.
13. Khalil M., Raila J., Ali M., Islam K.M.S., Schenk R., Krause J.-P., Schweigert F.J., Rawel H. Stability and bioavailability of lutein ester supplements from Tagetes flower prepared under food processing conditions. Journal of Functional Foods 2012, 4:602-610.
14. Koga T., Terao J. Phospholipids increase radical-scavenging activity of vitamin E in a bulk oil model system. Journal of Agricultural and Food Chemistry 1995, 43:1450-1454.
15. Linow F., Mieth G. Vergleichende analytische Untersuchungen an Soja- und Rapsphosphatiden. Die Nahrung 1967, 11:663-670.
16. Pelz R., Schmidt-Faber B., Heseker H. Carotenoid intake in the German National Food Consumption Survey. Zeitschrift für Ernährungswissenschaft 1998, 37:319-327.
17. Ribaya-Mercado J.D., Blumberg J.B. Lutein and zeaxanthin and their potential roles in disease prevention. Journal of the American College of Nutrition 2004, 23:567S-587S.
18. Ribeiro H.S., Guerrero J.M.M., Briviba K., Rechkemmer G., Schuchmann H.P., Schubert H. Cellular uptake of carotenoid-loaded oil-in-water emulsions in colon carcinoma cells in vitro. Journal of Agricultural and Food Chemistry 2006, 54:9366-9369.
19. Rydhag L. The importance of the phase behaviour of phospholipids for emulsion stability. Fette, Seifen, Anstrichmittel 1979, 81:168-173.
20. Saito H., Ishihara K. Antioxidant activity and active sites of phospholipids as antioxidants. Journal of the American Oil Chemists' Society 1997, 74:1531-1536.
21. Salami M., Moosavi-Movahedi A.A., Ehsani M.R., Yousefi R., Haertlé T., Chobert J.-M., Razavi S.H., Henrich R., Balalaie S., Ebadi S.A., Pourtakdoost S., Niasari-Naslaji A. Improvement of the antimicrobial and antioxidant activities of camel and bovine whey proteins by limited proteolysis. Journal of Agricultural and Food Chemistry 2010, 58:3297-3302.
22. Sies H., Stahl W., Sundquist A.R. Antioxidant functions of vitamins - vitamins E and C, beta-carotene, and other carotenoids. Annals of the New York Academy of Sciences 1992, 669:7-20.
23. Sommerburg O., Keunen J.E.E., Bird A.C., van Kuijk F.J.G.M. Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyes. The British Journal of Ophthalmology 1998, 82:907-910.
24. Subagio A., Morita N., Sawada S. Thermal isomerization of all-trans-lutein in a benzene solution. Bioscience, Biotechnology, and Biochemistry 1998, 62:2453-2456.
25. Tong L.M., Sasaki S., McClements D.J., Decker E.A. Mechanisms of the antioxidant activity of a high molecular weight fraction of whey. Journal of Agricultural and Food Chemistry 2000, 48:1473-1478.
26. van Het Hof K.H., West C.E., Weststrate J.A., Hautvast J.G. Dietary factors that affect the bioavailability of carotenoids. The Journal of Nutrition 2000, 130:503-506.
27. Yonekura L., Nagao A. Intestinal absorption of dietary carotenoids. Molecular Nutrition & Food Research 2007, 51:107-115.