Myrotheciumones: Bicyclic cytotoxic lactones isolated from an endophytic fungus of Ajuga decumbens

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 11, 2014, Pages 2504-2507

  Lin, Ting ^a   Wang, Guanghui ^a   Shan, Wenjun ^a   Zeng, Dequan ^a   Ding, Rong ^a   Jiang, Xin ^a   Zhu, Dan ^a   Liu, Xiaoxuan ^a   Yang, Shuiyuan ^a   Chen, Haifeng ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

Ajuga decumbens; Apoptosis; Cytotoxicity; Endophytic fungus; Myrotheciumones

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; LACTONE DERIVATIVE; MYROTHECIUMONE A; MYROTHECIUMONE B; UNCLASSIFIED DRUG; FUSED HETEROCYCLIC RINGS; LACTONE;

AJUGA; AJUGA DECUMBENS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL LINE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; ENDOPHYTIC FUNGUS; ENZYME ACTIVITY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MYROTHECIUM RORIDUM; NUCLEAR MAGNETIC RESONANCE; ASCOMYCETES; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; ISOLATION AND PURIFICATION; MICROBIOLOGY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

AJUGA DECUMBENS; FUNGI; MYROTHECIUM RORIDUM;

AJUGA; ANTINEOPLASTIC AGENTS; APOPTOSIS; ASCOMYCOTA; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HEP G2 CELLS; HUMANS; LACTONES; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84899914816     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.04.016     Document Type: Article

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