Optogenetic examination identifies a context-specific role for orexins/hypocretins in anxiety-related behavior

Physiology and Behavior

Volumn 130, Issue , 2014, Pages 182-190

  Heydendael, W ^a,b   Sengupta, A ^a   Beck, S ^a,b   Bhatnagar, S ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Anxiety; Hypocretins; Optogenetics; Orexins; Social interaction; Stress

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; OREXIN; OREXIN 1 RECEPTOR; RHODOPSIN; HCRTR1 PROTEIN, RAT; NEUROPEPTIDE; OREXIN RECEPTOR; OREXINS; PROTEIN C FOS; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; AROUSAL; ARTICLE; BRAIN REGION; CELL ACTIVATION; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENZYME PHOSPHORYLATION; EXPLORATORY BEHAVIOR; GROUP DYNAMICS; INTERNALIZATION; LATENT PERIOD; LOCUS CERULEUS; MALE; NERVE CELL; NONHUMAN; OPTOGENETICS; PARAVENTRICULAR THALAMIC NUCLEUS; PHOTOSTIMULATION; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SOCIAL INTERACTION; SOCIAL INTERACTION TEST; SOCIAL STRESS; WESTERN BLOTTING; ANIMAL; ANXIETY DISORDER; BRAIN; ENVIRONMENT; METABOLISM; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SOCIAL BEHAVIOR; SPRAGUE DAWLEY RAT; THALAMUS MIDLINE NUCLEUS;

ANIMALS; ANXIETY DISORDERS; AROUSAL; BRAIN; ENVIRONMENT; EXPLORATORY BEHAVIOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LOCUS COERULEUS; MALE; MIDLINE THALAMIC NUCLEI; MOTOR ACTIVITY; NEURONS; NEUROPEPTIDES; NEUROPSYCHOLOGICAL TESTS; OPTOGENETICS; OREXIN RECEPTORS; PHOSPHORYLATION; PREFRONTAL CORTEX; PROTO-ONCOGENE PROTEINS C-FOS; RATS, SPRAGUE-DAWLEY; SOCIAL BEHAVIOR;

EID: 84899903449     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2013.10.005     Document Type: Article

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