메뉴 건너뛰기




Volumn 12, Issue 1, 2014, Pages

Good guy or bad guy: The opposing roles of microRNA 125b in cancer

Author keywords

Cancer; MicroRNA; miR 125b; Oncogene; Tumor suppressor gene

Indexed keywords

MESSENGER RNA; MICRORNA 125B; MICRORNA; MIRN125 MICRORNA, HUMAN;

EID: 84899902278     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/1478-811X-12-30     Document Type: Review
Times cited : (144)

References (84)
  • 1
    • 0027751663 scopus 로고
    • The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • DOI 10.1016/0092-8674(93)90529-Y
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Lee RC, Feinbaum RL, Ambros V, Cell 1993 75 843 854 10.1016/0092-8674(93)90529-Y 8252621 (Pubitemid 24014542)
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 2
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • DOI 10.1038/nature03817
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Zhao Y, Samal E, Srivastava D, Nature 2005 436 214 220 10.1038/nature03817 15951802 (Pubitemid 41021266)
    • (2005) Nature , vol.436 , Issue.7048 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 3
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-Directed Cleavage of HOXB8 mRNA
    • DOI 10.1126/science.1097434
    • MicroRNA-directed cleavage of HOXB8 mRNA. Yekta S, Shih IH, Bartel DP, Science 2004 304 594 596 10.1126/science.1097434 15105502 (Pubitemid 38541919)
    • (2004) Science , vol.304 , Issue.5670 , pp. 594-596
    • Yekta, S.1    Shih, I.-H.2    Bartel, D.P.3
  • 5
    • 84871609151 scopus 로고    scopus 로고
    • MicroRNAs and neurodegeneration: Role and impact
    • 10.1016/j.tcb.2012.08.013 23026030
    • MicroRNAs and neurodegeneration: role and impact. Abe M, Bonini N, Trends Cell Biol 2013 23 30 36 10.1016/j.tcb.2012.08.013 23026030
    • (2013) Trends Cell Biol , vol.23 , pp. 30-36
    • Abe, M.1    Bonini, N.2
  • 7
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • DOI 10.1038/nrg1379
    • MicroRNAs: small RNAs with a big role in gene regulation. He L, Hannon GJ, Nat Rev Genet 2004 5 522 531 10.1038/nrg1379 15211354 (Pubitemid 38868508)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 8
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • DOI 10.1038/nmeth1079, PII NMETH1079
    • MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Ebert MS, Neilson JR, Sharp PA, Nat Meth 2007 4 721 726 10.1038/nmeth1079 (Pubitemid 47338166)
    • (2007) Nature Methods , vol.4 , Issue.9 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 9
    • 64549109671 scopus 로고    scopus 로고
    • Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells
    • 10.1093/nar/gkp040 19223327
    • Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells. Haraguchi T, Ozaki Y, Iba H, Nucleic Acids Res 2009 37 43 10.1093/nar/gkp040 19223327
    • (2009) Nucleic Acids Res , vol.37 , pp. 543
    • Haraguchi, T.1    Ozaki, Y.2    Iba, H.3
  • 11
    • 67650711156 scopus 로고    scopus 로고
    • MicroRNAs in cancer
    • 10.1146/annurev.med.59.053006.104707 19630570
    • MicroRNAs in Cancer. Garzon R, Calin GA, Croce CM, Annu Rev Med 2009 60 167 179 10.1146/annurev.med.59.053006.104707 19630570
    • (2009) Annu Rev Med , vol.60 , pp. 167-179
    • Garzon, R.1    Calin, G.A.2    Croce, C.M.3
  • 12
    • 84874726726 scopus 로고    scopus 로고
    • MiRCancer: A microRNA-cancer association database constructed by text mining on literature
    • 10.1093/bioinformatics/btt014 23325619
    • miRCancer: a microRNA-cancer association database constructed by text mining on literature. Xie B, Ding Q, Han H, Wu D, Bioinformatics 2013 29 638 644 10.1093/bioinformatics/btt014 23325619
    • (2013) Bioinformatics , vol.29 , pp. 638-644
    • Xie, B.1    Ding, Q.2    Han, H.3    Wu, D.4
  • 13
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. Elegans
    • DOI 10.1016/0092-8674(93)90530-4
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Wightman B, Ha I, Ruvkun G, Cell 1993 75 855 862 10.1016/0092-8674(93)90530-4 8252622 (Pubitemid 24014543)
    • (1993) Cell , vol.75 , Issue.5 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 14
    • 80052795484 scopus 로고    scopus 로고
    • Uncovering new functions for microRNAs in Caenorhabditis elegans
    • 10.1016/j.cub.2011.07.027 21920301
    • Uncovering new functions for microRNAs in Caenorhabditis elegans. Abbott AL, Curr Biol 2011 21 668 R671 10.1016/j.cub.2011.07.027 21920301
    • (2011) Curr Biol , vol.21
    • Abbott, A.L.1
  • 15
    • 84897980698 scopus 로고    scopus 로고
    • The lin-4 microRNA: The ultimate micromanager
    • 24584060
    • The lin-4 microRNA: The ultimate micromanager. Esquela-Kerscher A, Cell Cycle 2014 13 1060 1061 24584060
    • (2014) Cell Cycle , vol.13 , pp. 1060-1061
    • Esquela-Kerscher, A.1
  • 19
    • 84879416696 scopus 로고    scopus 로고
    • MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression
    • 10.1038/onc.2012.307 22797068
    • MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression. Kappelmann M, Kuphal S, Meister G, Vardimon L, Bosserhoff AK, Oncogene 2013 32 2984 2991 10.1038/onc.2012.307 22797068
    • (2013) Oncogene , vol.32 , pp. 2984-2991
    • Kappelmann, M.1    Kuphal, S.2    Meister, G.3    Vardimon, L.4    Bosserhoff, A.K.5
  • 20
    • 84859543307 scopus 로고    scopus 로고
    • MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2
    • 22460089
    • MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2. Shang C, Lu YM, Meng LR, Med Sci Monit 2012 18 R149 BR155 22460089
    • (2012) Med Sci Monit , vol.18
    • Shang, C.1    Lu, Y.M.2    Meng, L.R.3
  • 21
    • 67449087552 scopus 로고    scopus 로고
    • Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy
    • 10.1002/gcc.20666 19396866
    • Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy. Henson BJ, Bhattacharjee S, O'Dee DM, Feingold E, Gollin SM, Genes Chromosomes Cancer 2009 48 569 582 10.1002/gcc.20666 19396866
    • (2009) Genes Chromosomes Cancer , vol.48 , pp. 569-582
    • Henson, B.J.1    Bhattacharjee, S.2    O'Dee, D.M.3    Feingold, E.4    Gollin, S.M.5
  • 22
    • 83055163471 scopus 로고    scopus 로고
    • MiR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3
    • 10.1016/j.bbrc.2011.10.117 22093834
    • miR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3. Liu LH, Li H, Li JP, Zhong H, Zhang HC, Chen J, Xiao T, Biochem Biophys Res Commun 2011 416 31 38 10.1016/j.bbrc.2011.10.117 22093834
    • (2011) Biochem Biophys Res Commun , vol.416 , pp. 31-38
    • Liu, L.H.1    Li, H.2    Li, J.P.3    Zhong, H.4    Zhang, H.C.5    Chen, J.6    Xiao, T.7
  • 24
  • 25
    • 78650736233 scopus 로고    scopus 로고
    • MicroRNA miR-125b causes leukemia
    • 10.1073/pnas.1016611107 21118985
    • MicroRNA miR-125b causes leukemia. Bousquet M, Harris M, Zhou B, Lodish H, Proc Natl Acad Sci 2010 107 21558 21563 10.1073/pnas.1016611107 21118985
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 21558-21563
    • Bousquet, M.1    Harris, M.2    Zhou, B.3    Lodish, H.4
  • 26
    • 84856068645 scopus 로고    scopus 로고
    • MiR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells
    • 10.1074/jbc.M111.285718 22139839
    • miR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells. Willimott S, Wagner SD, J Biol Chem 2012 287 2608 2617 10.1074/jbc.M111.285718 22139839
    • (2012) J Biol Chem , vol.287 , pp. 2608-2617
    • Willimott, S.1    Wagner, S.D.2
  • 27
    • 80055100472 scopus 로고    scopus 로고
    • MiR-125b, a target of CDX2, regulates cell differentiation through repression of the core binding factor in hematopoietic malignancies
    • 10.1074/jbc.M111.269670 21903586
    • miR-125b, a target of CDX2, regulates cell differentiation through repression of the core binding factor in hematopoietic malignancies. Lin KY, Zhang XJ, Feng DD, Zhang H, Zeng CW, Han BW, Zhou AD, Qu LH, Xu L, Chen YQ, J Biol Chem 2011 286 38253 38263 10.1074/jbc.M111.269670 21903586
    • (2011) J Biol Chem , vol.286 , pp. 38253-38263
    • Lin, K.Y.1    Zhang, X.J.2    Feng, D.D.3    Zhang, H.4    Zeng, C.W.5    Han, B.W.6    Zhou, A.D.7    Qu, L.H.8    Xu, L.9    Chen, Y.Q.10
  • 29
  • 31
    • 66749182257 scopus 로고    scopus 로고
    • MiR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf
    • 10.1159/000218181 19471102
    • MiR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf. Xia HF, He TZ, Liu CM, Cui Y, Song PP, Jin XH, Ma X, Cell Physiol Biochem 2009 23 347 358 10.1159/000218181 19471102
    • (2009) Cell Physiol Biochem , vol.23 , pp. 347-358
    • Xia, H.F.1    He, T.Z.2    Liu, C.M.3    Cui, Y.4    Song, P.P.5    Jin, X.H.6    Ma, X.7
  • 33
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • DOI 10.1038/nrc1997, PII NRC1997
    • MicroRNA signatures in human cancers. Calin GA, Croce CM, Nat Rev Cancer 2006 6 857 866 10.1038/nrc1997 17060945 (Pubitemid 44629897)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 35
    • 27644442420 scopus 로고    scopus 로고
    • Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia [9]
    • DOI 10.1038/sj.leu.2403938, PII 2403938
    • Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia. Sonoki T, Iwanaga E, Mitsuya H, Asou N, Leukemia 2005 19 2009 2010 10.1038/sj.leu.2403938 16151463 (Pubitemid 41554016)
    • (2005) Leukemia , vol.19 , Issue.11 , pp. 2009-2010
    • Sonoki, T.1    Iwanaga, E.2    Mitsuya, H.3    Asou, N.4
  • 36
    • 20444440706 scopus 로고    scopus 로고
    • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • DOI 10.1074/jbc.M412247200
    • Depletion of Human Micro-RNA miR-125b Reveals That It Is Critical for the Proliferation of Differentiated Cells but Not for the Down-regulation of Putative Targets during Differentiation. Lee YS, Kim HK, Chung S, Kim K-S, Dutta A, J Biol Chem 2005 280 16635 16641 10.1074/jbc.M412247200 15722555 (Pubitemid 41389120)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 16635-16641
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3    Kim, K.-S.4    Dutta, A.5
  • 39
    • 1542353401 scopus 로고    scopus 로고
    • Control of apoptosis by p53
    • DOI 10.1038/sj.onc.1207116, Apoptosis - Part 2
    • Control of apoptosis by p53. Fridman JS, Lowe SW, Oncogene 2003 22 9030 9040 10.1038/sj.onc.1207116 14663481 (Pubitemid 38121703)
    • (2003) Oncogene , vol.22 , Issue.56 REV. ISS. 8 , pp. 9030-9040
    • Fridman, J.S.1    Lowe, S.W.2
  • 40
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
    • DOI 10.1074/jbc.M609383200
    • Coordinate Suppression of ERBB2 and ERBB3 by Enforced Expression of Micro-RNA miR-125a or miR-125b. Scott GK, Goga A, Bhaumik D, Berger CE, Sullivan CS, Benz CC, J Biol Chem 2007 282 1479 1486 10.1074/jbc.M609383200 17110380 (Pubitemid 47076526)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.2 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3    Berger, C.E.4    Sullivan, C.S.5    Benz, C.C.6
  • 41
    • 0034766736 scopus 로고    scopus 로고
    • Biology of HER2 and its importance in breast cancer
    • Biology of HER2 and its importance in breast cancer. Yarden Y, Oncology 2001 61 Suppl 2 1 13 (Pubitemid 33033419)
    • (2001) Oncology , vol.61 , Issue.SUPPL. 2 , pp. 1-13
    • Yarden, Y.1
  • 42
    • 38449108764 scopus 로고    scopus 로고
    • Molecular mechanisms of erbB2-mediated breast cancer chemoresistance
    • 10.1007/978-0-387-74039-3-9 17993237
    • Molecular mechanisms of erbB2-mediated breast cancer chemoresistance. Tan M, Yu D, Adv Exp Med Biol 2007 608 119 129 10.1007/978-0-387-74039-3-9 17993237
    • (2007) Adv Exp Med Biol , vol.608 , pp. 119-129
    • Tan, M.1    Yu, D.2
  • 44
    • 84871273105 scopus 로고    scopus 로고
    • Circulating miR-125b is a novel biomarker for screening non-small-cell lung cancer and predicts poor prognosis
    • 10.1007/s00432-012-1285-0 22806310
    • Circulating miR-125b is a novel biomarker for screening non-small-cell lung cancer and predicts poor prognosis. Yuxia M, Zhennan T, Wei Z, J Cancer Res Clin Oncol 2012 138 2045 2050 10.1007/s00432-012-1285-0 22806310
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 2045-2050
    • Yuxia, M.1    Zhennan, T.2    Wei, Z.3
  • 46
    • 77956288810 scopus 로고    scopus 로고
    • MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output
    • 10.1073/pnas.1009798107 20660734
    • MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output. O'Connell RM, Chaudhuri AA, Rao DS, Gibson WS, Balazs AB, Baltimore D, Proc Natl Acad Sci U S A 2010 107 14235 14240 10.1073/pnas.1009798107 20660734
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14235-14240
    • O'Connell, R.M.1    Chaudhuri, A.A.2    Rao, D.S.3    Gibson, W.S.4    Balazs, A.B.5    Baltimore, D.6
  • 47
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • DOI 10.1038/ncb1596, PII NCB1596
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO, Nat Cell Biol 2007 9 654 659 10.1038/ncb1596 17486113 (Pubitemid 47214727)
    • (2007) Nature Cell Biology , vol.9 , Issue.6 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 48
    • 84873532679 scopus 로고    scopus 로고
    • Serum microRNA 125b as a diagnostic or prognostic biomarker for advanced NSCLC patients receiving cisplatin-based chemotherapy
    • 10.1038/aps.2012.125 22983388
    • Serum microRNA 125b as a diagnostic or prognostic biomarker for advanced NSCLC patients receiving cisplatin-based chemotherapy.Li H-J, Hua F, Wang B, Mao W, Feng X-R, Li J-Y, Wang X, Acta Pharmacol Sin 2013 34 309 313 10.1038/aps.2012.125 22983388
    • (2013) Acta Pharmacol Sin , vol.34 , pp. 309-313
    • Li, H.-J.1    Hua, F.2    Wang, B.3    Mao, W.4    Feng, X.-R.5    Li, J.-Y.6    Wang, X.7
  • 49
    • 79951972107 scopus 로고    scopus 로고
    • MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3
    • 10.1002/ijc.25509 20549700
    • MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3. Huang L, Luo J, Cai Q, Pan Q, Zeng H, Guo Z, Dong W, Huang J, Lin T, Int J Cancer 2011 128 1758 1769 10.1002/ijc.25509 20549700
    • (2011) Int J Cancer , vol.128 , pp. 1758-1769
    • Huang, L.1    Luo, J.2    Cai, Q.3    Pan, Q.4    Zeng, H.5    Guo, Z.6    Dong, W.7    Huang, J.8    Lin, T.9
  • 50
    • 84872711759 scopus 로고    scopus 로고
    • MicroRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer
    • 23425975
    • microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer. Wu D, Ding J, Wang L, Pan H, Zhou Z, Zhou J, Qu P, Oncol Lett 2013 5 829 834 23425975
    • (2013) Oncol Lett , vol.5 , pp. 829-834
    • Wu, D.1    Ding, J.2    Wang, L.3    Pan, H.4    Zhou, Z.5    Zhou, J.6    Qu, P.7
  • 51
    • 59349090919 scopus 로고    scopus 로고
    • MicroRNA-143 as a Tumor Suppressor for Bladder Cancer
    • 10.1016/j.juro.2008.10.149 19157460
    • MicroRNA-143 as a Tumor Suppressor for Bladder Cancer. Lin T, Dong W, Huang J, Pan Q, Fan X, Zhang C, Huang L, J Urol 2009 181 1372 1380 10.1016/j.juro.2008.10.149 19157460
    • (2009) J Urol , vol.181 , pp. 1372-1380
    • Lin, T.1    Dong, W.2    Huang, J.3    Pan, Q.4    Fan, X.5    Zhang, C.6    Huang, L.7
  • 54
    • 77953178125 scopus 로고    scopus 로고
    • MUCIN 1 ONCOPROTEIN EXPRESSION IS SUPPRESSED by the miR-125b ONCOMIR
    • 10.1177/1947601909357933 20729973
    • MUCIN 1 ONCOPROTEIN EXPRESSION IS SUPPRESSED BY THE miR-125b ONCOMIR. Rajabi H, Jin C, Ahmad R, McClary C, Joshi MD, Kufe D, Genes Cancer 2010 1 62 68 10.1177/1947601909357933 20729973
    • (2010) Genes Cancer , vol.1 , pp. 62-68
    • Rajabi, H.1    Jin, C.2    Ahmad, R.3    McClary, C.4    Joshi, M.D.5    Kufe, D.6
  • 55
    • 82955237238 scopus 로고    scopus 로고
    • A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs
    • 10.1038/onc.2011.197 21643012
    • A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs. McKinsey EL, Parrish JK, Irwin AE, Niemeyer BF, Kern HB, Birks DK, Jedlicka P, Oncogene 2011 30 4910 4920 10.1038/onc.2011.197 21643012
    • (2011) Oncogene , vol.30 , pp. 4910-4920
    • McKinsey, E.L.1    Parrish, J.K.2    Irwin, A.E.3    Niemeyer, B.F.4    Kern, H.B.5    Birks, D.K.6    Jedlicka, P.7
  • 56
    • 84895922568 scopus 로고    scopus 로고
    • MiR-125b inhibits cell biological progression of Ewing's sarcoma by suppressing the PI3K/Akt signalling pathway
    • 10.1111/cpr.12093 24517182
    • MiR-125b inhibits cell biological progression of Ewing's sarcoma by suppressing the PI3K/Akt signalling pathway. Li J, You T, Jing J, Cell Prolif 2014 47 152 160 10.1111/cpr.12093 24517182
    • (2014) Cell Prolif , vol.47 , pp. 152-160
    • Li, J.1    You, T.2    Jing, J.3
  • 57
    • 84879412522 scopus 로고    scopus 로고
    • MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R
    • 10.1038/onc.2012.318 22824797
    • MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R. Gong J, Zhang JP, Li B, Zeng C, You K, Chen MX, Yuan Y, Zhuang SM, Oncogene 2013 32 3071 3079 10.1038/onc.2012.318 22824797
    • (2013) Oncogene , vol.32 , pp. 3071-3079
    • Gong, J.1    Zhang, J.P.2    Li, B.3    Zeng, C.4    You, K.5    Chen, M.X.6    Yuan, Y.7    Zhuang, S.M.8
  • 58
    • 84864338271 scopus 로고    scopus 로고
    • MicroRNA-125b Functions as a Tumor Suppressor in Hepatocellular Carcinoma Cells
    • 10.3390/ijms13078762 22942733
    • MicroRNA-125b Functions as a Tumor Suppressor in Hepatocellular Carcinoma Cells. Jia HY, Wang YX, Yan WT, Li HY, Tian YZ, Wang SM, Zhao HL, Int J Mol Sci 2012 13 8762 8774 10.3390/ijms13078762 22942733
    • (2012) Int J Mol Sci , vol.13 , pp. 8762-8774
    • Jia, H.Y.1    Wang, Y.X.2    Yan, W.T.3    Li, H.Y.4    Tian, Y.Z.5    Wang, S.M.6    Zhao, H.L.7
  • 59
    • 84862805764 scopus 로고    scopus 로고
    • MicroRNA-125b induces cancer cell apoptosis through suppression of Bcl-2 expression
    • 10.1016/j.jgg.2011.12.003 22293115
    • MicroRNA-125b induces cancer cell apoptosis through suppression of Bcl-2 expression. Zhao A, Zeng Q, Xie X, Zhou J, Yue W, Li Y, Pei X, J Genet Genomics 2012 39 29 35 10.1016/j.jgg.2011.12.003 22293115
    • (2012) J Genet Genomics , vol.39 , pp. 29-35
    • Zhao, A.1    Zeng, Q.2    Xie, X.3    Zhou, J.4    Yue, W.5    Li, Y.6    Pei, X.7
  • 61
    • 78049521995 scopus 로고    scopus 로고
    • MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2
    • 10.1002/hep.23904 20827722
    • MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2. Liang L, Wong CM, Ying Q, Fan DN, Huang S, Ding J, Yao J, Yan M, Li J, Yao M, Ng IO, He X, Hepatology 2010 52 1731 1740 10.1002/hep.23904 20827722
    • (2010) Hepatology , vol.52 , pp. 1731-1740
    • Liang, L.1    Wong, C.M.2    Ying, Q.3    Fan, D.N.4    Huang, S.5    Ding, J.6    Yao, J.7    Yan, M.8    Li, J.9    Yao, M.10    Ng, I.O.11    He, X.12
  • 63
    • 77957796525 scopus 로고    scopus 로고
    • MiR-125b targets BCL3 and suppresses ovarian cancer proliferation
    • 10.1002/ijc.25575 20658525
    • MiR-125b targets BCL3 and suppresses ovarian cancer proliferation. Guan Y, Yao H, Zheng Z, Qiu G, Sun K, Int J Cancer 2011 128 2274 2283 10.1002/ijc.25575 20658525
    • (2011) Int J Cancer , vol.128 , pp. 2274-2283
    • Guan, Y.1    Yao, H.2    Zheng, Z.3    Qiu, G.4    Sun, K.5
  • 64
    • 84874274333 scopus 로고    scopus 로고
    • Roles and Mechanism of miR-199a and miR-125b in Tumor Angiogenesis
    • 10.1371/journal.pone.0056647 23437196
    • Roles and Mechanism of miR-199a and miR-125b in Tumor Angiogenesis. He J, Jing Y, Li W, Qian X, Xu Q, Li F-S, Liu L-Z, Jiang B-H, Jiang Y, PLoS One 2013 8 56647 10.1371/journal.pone.0056647 23437196
    • (2013) PLoS One , vol.8 , pp. 556647
    • He, J.1    Jing, Y.2    Li, W.3    Qian, X.4    Xu, Q.5    Li, F.-S.6    Liu, L.-Z.7    Jiang, B.-H.8    Jiang, Y.9
  • 65
    • 84886414256 scopus 로고    scopus 로고
    • MiR-125b inhibits Connexin43 and promotes glioma growth
    • 10.1007/s10571-013-9980-1 24046143
    • miR-125b inhibits Connexin43 and promotes glioma growth. Jin Z, Xu S, Yu H, Yang B, Zhao H, Zhao G, Cell Mol Neurobiol 2013 33 1143 1148 10.1007/s10571-013-9980-1 24046143
    • (2013) Cell Mol Neurobiol , vol.33 , pp. 1143-1148
    • Jin, Z.1    Xu, S.2    Yu, H.3    Yang, B.4    Zhao, H.5    Zhao, G.6
  • 66
    • 73649147994 scopus 로고    scopus 로고
    • MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation
    • 19948152
    • MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation. Shi L, Zhang J, Pan T, Zhou J, Gong W, Liu N, Fu Z, You Y, Brain Res 2010 1312 120 126 19948152
    • (2010) Brain Res , vol.1312 , pp. 120-126
    • Shi, L.1    Zhang, J.2    Pan, T.3    Zhou, J.4    Gong, W.5    Liu, N.6    Fu, Z.7    You, Y.8
  • 67
    • 38049100559 scopus 로고    scopus 로고
    • An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells
    • 10.1073/pnas.0706641104 18056640
    • An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells. Shi XB, Xue L, Yang J, Ma AH, Zhao J, Xu M, Tepper CG, Evans CP, Kung HJ, DeVere White RW, Proc Natl Acad Sci U S A 2007 104 19983 19988 10.1073/pnas.0706641104 18056640
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19983-19988
    • Shi, X.B.1    Xue, L.2    Yang, J.3    Ma, A.H.4    Zhao, J.5    Xu, M.6    Tepper, C.G.7    Evans, C.P.8    Kung, H.J.9    Devere White, R.W.10
  • 68
    • 84876046735 scopus 로고    scopus 로고
    • Oncomir miR-125b suppresses p14 (ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer
    • 10.1371/journal.pone.0061064 23585871
    • Oncomir miR-125b suppresses p14 (ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer. Amir S, Ma AH, Shi XB, Xue L, Kung HJ, Devere White RW, PLoS One 2013 8 61064 10.1371/journal.pone.0061064 23585871
    • (2013) PLoS One , vol.8 , pp. 561064
    • Amir, S.1    Ma, A.H.2    Shi, X.B.3    Xue, L.4    Kung, H.J.5    Devere White, R.W.6
  • 69
    • 84896394889 scopus 로고    scopus 로고
    • Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells
    • 23503464
    • Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells. Sun D, Layer R, Mueller AC, Cichewicz MA, Negishi M, Paschal BM, Dutta A, Oncogene 2013 33 1448 1457 23503464
    • (2013) Oncogene , vol.33 , pp. 1448-1457
    • Sun, D.1    Layer, R.2    Mueller, A.C.3    Cichewicz, M.A.4    Negishi, M.5    Paschal, B.M.6    Dutta, A.7
  • 70
    • 40749090479 scopus 로고    scopus 로고
    • Widespread deregulation of microRNA expression in human prostate cancer
    • DOI 10.1038/sj.onc.1210809, PII 1210809
    • Widespread deregulation of microRNA expression in human prostate cancer. Ozen M, Creighton CJ, Ozdemir M, Ittmann M, Oncogene 2008 27 1788 1793 10.1038/sj.onc.1210809 17891175 (Pubitemid 351380263)
    • (2008) Oncogene , vol.27 , Issue.12 , pp. 1788-1793
    • Ozen, M.1    Creighton, C.J.2    Ozdemir, M.3    Ittmann, M.4
  • 71
    • 70349312583 scopus 로고    scopus 로고
    • MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets
    • 10.1128/MCB.01694-08 19635812
    • MicroRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets. Le MTN, Xie H, Zhou B, Chia PH, Rizk P, Um M, Udolph G, Yang H, Lim B, Lodish HF, Mol Cell Biol 2009 29 5290 5305 10.1128/MCB.01694-08 19635812
    • (2009) Mol Cell Biol , vol.29 , pp. 5290-5305
    • Le, M.T.N.1    Xie, H.2    Zhou, B.3    Chia, P.H.4    Rizk, P.5    Um, M.6    Udolph, G.7    Yang, H.8    Lim, B.9    Lodish, H.F.10
  • 72
    • 84861605685 scopus 로고    scopus 로고
    • Opposing roles of connexin43 in glioma progression
    • 10.1016/j.bbamem.2011.10.022 22063721
    • Opposing roles of connexin43 in glioma progression. Sin WC, Crespin S, Mesnil M, Biochim Biophys Acta 2012 1818 2058 2067 10.1016/j.bbamem.2011.10.022 22063721
    • (2012) Biochim Biophys Acta , vol.1818 , pp. 2058-2067
    • Sin, W.C.1    Crespin, S.2    Mesnil, M.3
  • 73
    • 84896875131 scopus 로고    scopus 로고
    • Androgens regulate ovarian follicular development by increasing follicle stimulating hormone receptor and microRNA-125b expression
    • 10.1073/pnas.1312213111 24368852
    • Androgens regulate ovarian follicular development by increasing follicle stimulating hormone receptor and microRNA-125b expression. Sen A, Prizant H, Light A, Biswas A, Hayes E, Lee HJ, Barad D, Gleicher N, Hammes SR, Proc Natl Acad Sci U S A 2014 111 308 313 10.1073/pnas.1312213111 24368852
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 308-313
    • Sen, A.1    Prizant, H.2    Light, A.3    Biswas, A.4    Hayes, E.5    Lee, H.J.6    Barad, D.7    Gleicher, N.8    Hammes, S.R.9
  • 74
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • 10.1016/j.cell.2011.02.013 21376230
    • Hallmarks of Cancer: The Next Generation. Hanahan D, Weinberg Robert A, Cell 2011 144 646 674 10.1016/j.cell.2011.02.013 21376230
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg Robert, A.2
  • 75
    • 0036129489 scopus 로고    scopus 로고
    • The p53 pathway in breast cancer
    • DOI 10.1186/bcr426
    • The p53 pathway in breast cancer. Gasco M, Shami S, Crook T, Breast Cancer Res 2002 4 70 76 11879567 (Pubitemid 34248123)
    • (2002) Breast Cancer Research , vol.4 , Issue.2 , pp. 70-76
    • Gasco, M.1    Shami, S.2    Crook, T.3
  • 76
    • 0025894713 scopus 로고
    • P53 mutations in human cancers
    • p53 mutations in human cancers. Hollstein M, Sidransky D, Vogelstein B, Harris CC, Science 1991 253 49 53 10.1126/science.1905840 1905840 (Pubitemid 21917115)
    • (1991) Science , vol.253 , Issue.5015 , pp. 49-53
    • Hollsteln, M.1    Sidransky, D.2    Vogelstein, B.3    Harris, C.C.4
  • 77
    • 77949875682 scopus 로고    scopus 로고
    • MicroRNA control of signal transduction
    • 20216554
    • MicroRNA control of signal transduction. Inui M, Martello G, Piccolo S, Nat Rev Mol Cell Biol 2010 11 252 263 20216554
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 252-263
    • Inui, M.1    Martello, G.2    Piccolo, S.3
  • 78
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: The DNA hypermethylome
    • DOI 10.1093/hmg/ddm018, Cancer Genetics
    • Epigenetic gene silencing in cancer: the DNA hypermethylome. Esteller M, Hum Mol Genet 2007 16 50 R59 10.1093/hmg/ddm018 17613547 (Pubitemid 47241842)
    • (2007) Human Molecular Genetics , vol.16 , Issue.R1
    • Esteller, M.1
  • 79
    • 61349191567 scopus 로고    scopus 로고
    • The TRIM-NHL protein TRIM32 activates micrornas and prevents self-renewal in mouse neural progenitors
    • 10.1016/j.cell.2008.12.024 19269368
    • The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors. Schwamborn JC, Berezikov E, Knoblich JA, Cell 2009 136 913 925 10.1016/j.cell.2008.12.024 19269368
    • (2009) Cell , vol.136 , pp. 913-925
    • Schwamborn, J.C.1    Berezikov, E.2    Knoblich, J.A.3
  • 80
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • The hallmarks of cancer. Hanahan D, Weinberg RA, Cell 2000 100 57 70 10.1016/S0092-8674(00)81683-9 10647931 (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 82
    • 84858041599 scopus 로고    scopus 로고
    • Androgen receptor signaling in prostate cancer development and progression
    • 10.4103/1477-3163.83937 21886458
    • Androgen receptor signaling in prostate cancer development and progression. Tindall D, Lonergan P, J Carcinog 2011 10 20 10.4103/1477-3163. 83937 21886458
    • (2011) J Carcinog , vol.10 , pp. 20
    • Tindall, D.1    Lonergan, P.2
  • 83
    • 64249106832 scopus 로고    scopus 로고
    • Mouse xenograft models vs GEM models for human cancer therapeutics
    • 10.1242/dmm.000976 19048064
    • Mouse xenograft models vs GEM models for human cancer therapeutics. Richmond A, Su Y, Dis Model Mech 2008 1 78 82 10.1242/dmm.000976 19048064
    • (2008) Dis Model Mech , vol.1 , pp. 78-82
    • Richmond, A.1    Su, Y.2
  • 84
    • 83255186696 scopus 로고    scopus 로고
    • MicroRNA therapeutics
    • 10.1038/gt.2011.50 21525952
    • MicroRNA therapeutics. Broderick JA, Zamore PD, Gene Ther 2011 18 1104 1110 10.1038/gt.2011.50 21525952
    • (2011) Gene Ther , vol.18 , pp. 1104-1110
    • Broderick, J.A.1    Zamore, P.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.