메뉴 건너뛰기




Volumn 164, Issue , 2014, Pages 35-42

Short-term treatment of adult male zebrafish (Danio Rerio) with 17α-ethinyl estradiol affects the transcription of genes involved in development and male sex differentiation

Author keywords

17 Ethinyl estradiol; Biomarker; Endocrine disruptors; Gene regulation; Gonads; Sex differentiation; Zebrafish

Indexed keywords

ANDROGEN RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 19A; DOUBLE SEX AND MAB RELATED PROTEIN; ESTROGEN RECEPTOR; ETHINYLESTRADIOL; MESSENGER RNA; MUELLERIAN INHIBITING FACTOR; NUCLEAR RECEPTOR SUBFAMILY 5 GROUP NUMBER 1B; PROTEIN; STEROID RECEPTOR; TRANSCRIPTION FACTOR SOX9; TRANSCRIPTION FACTOR SOX9A; UNCLASSIFIED DRUG; VITELLOGENIN; AROMATASE; CYP19A PROTEIN, ZEBRAFISH; DMRT1 PROTEIN; ESTROGEN RECEPTOR BETA; SOX9A PROTEIN, ZEBRAFISH; STEROIDOGENIC FACTOR 1; TRANSCRIPTION FACTOR; WATER POLLUTANT; ZEBRAFISH PROTEIN;

EID: 84899872779     PISSN: 15320456     EISSN: 18781659     Source Type: Journal    
DOI: 10.1016/j.cbpc.2014.04.003     Document Type: Article
Times cited : (42)

References (77)
  • 1
    • 44649110723 scopus 로고    scopus 로고
    • Modulation of steroidogenesis and xenobiotic biotransformation responses in zebrafish (Danio rerio) exposed to water-soluble fraction of crude oil
    • A. Arukwe, T. Nordtug, T.M. Kortner, A.S. Mortensen, and O.G. Brakstad Modulation of steroidogenesis and xenobiotic biotransformation responses in zebrafish (Danio rerio) exposed to water-soluble fraction of crude oil Environ. Res. 107 2008 362 370
    • (2008) Environ. Res. , vol.107 , pp. 362-370
    • Arukwe, A.1    Nordtug, T.2    Kortner, T.M.3    Mortensen, A.S.4    Brakstad, O.G.5
  • 2
    • 2542420854 scopus 로고    scopus 로고
    • Impacts of 17β-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval-, juvenile- and adult-life stages in zebrafish (Danio rerio)
    • F. Brion, C.R. Tyler, X. Palazzi, B. Laillet, J.M. Porcher, J. Garric, and P. Flammarion Impacts of 17β-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval-, juvenile- and adult-life stages in zebrafish (Danio rerio) Aquat. Toxicol. 68 2004 193
    • (2004) Aquat. Toxicol. , vol.68 , pp. 193
    • Brion, F.1    Tyler, C.R.2    Palazzi, X.3    Laillet, B.4    Porcher, J.M.5    Garric, J.6    Flammarion, P.7
  • 4
    • 77950381638 scopus 로고    scopus 로고
    • Levels of 17β-estradiol receptors expressed in embryonic and adult zebrafish following in vivo treatment of natural or synthetic ligands
    • G. Chandrasekar, A. Archer, J.-Å. Gustafsson, and M. Andersson Lendahl Levels of 17β-estradiol receptors expressed in embryonic and adult zebrafish following in vivo treatment of natural or synthetic ligands PLoS One 5 2010 e9678
    • (2010) PLoS One , vol.5 , pp. 9678
    • Chandrasekar, G.1    Archer, A.2    Gustafsson, J.-Å.3    Andersson Lendahl, M.4
  • 6
    • 74349104943 scopus 로고    scopus 로고
    • Generation of a fluorescent transgenic zebrafish for detection of environmental estrogens
    • H. Chen, J. Hu, J. Yang, Y. Wang, H. Xu, Q. Jiang, Y. Gong, Y. Gu, and H. Song Generation of a fluorescent transgenic zebrafish for detection of environmental estrogens Aquat. Toxicol. 96 2010 53 61
    • (2010) Aquat. Toxicol. , vol.96 , pp. 53-61
    • Chen, H.1    Hu, J.2    Yang, J.3    Wang, Y.4    Xu, H.5    Jiang, Q.6    Gong, Y.7    Gu, Y.8    Song, H.9
  • 7
    • 84885756135 scopus 로고    scopus 로고
    • Multiple structurally distinct ERα mRNA variants in zebrafish are differentially expressed by tissue type, stage of development and estrogen exposure
    • K.A. Cotter, A. Yershov, A. Novillo, and G.V. Callard Multiple structurally distinct ERα mRNA variants in zebrafish are differentially expressed by tissue type, stage of development and estrogen exposure Gen. Comp. Endocrinol. 194 2013 217 229
    • (2013) Gen. Comp. Endocrinol. , vol.194 , pp. 217-229
    • Cotter, K.A.1    Yershov, A.2    Novillo, A.3    Callard, G.V.4
  • 8
    • 33646793302 scopus 로고    scopus 로고
    • Epigenetics, evolution, endocrine disruption, health, and disease
    • D. Crews, and J.A. McLachlan Epigenetics, evolution, endocrine disruption, health, and disease Endocrinology 147 2006 s4 s10
    • (2006) Endocrinology , vol.147
    • Crews, D.1    McLachlan, J.A.2
  • 9
    • 1542375216 scopus 로고    scopus 로고
    • Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio)
    • DOI 10.1016/j.aquatox.2003.10.008, PII S0166445X03002236
    • M. Fenske, and H. Segner Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio) Aquat. Toxicol. 67 2004 105 126 (Pubitemid 38299338)
    • (2004) Aquatic Toxicology , vol.67 , Issue.2 , pp. 105-126
    • Fenske, M.1    Segner, H.2
  • 10
    • 18244367401 scopus 로고    scopus 로고
    • An environmentally relevant concentration of estrogen induces arrest of male gonad development in zebrafish, Danio rerio
    • M. Fenske, G. Maack, C. Schäfers, and H. Segner An environmentally relevant concentration of estrogen induces arrest of male gonad development in zebrafish, Danio rerio Environ. Toxicol. Chem. 24 2005 10881098
    • (2005) Environ. Toxicol. Chem. , vol.24 , pp. 10881098
    • Fenske, M.1    Maack, G.2    Schäfers, C.3    Segner, H.4
  • 12
    • 33846850582 scopus 로고    scopus 로고
    • Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminization in fish
    • DOI 10.1016/j.aquatox.2006.12.003, PII S0166445X06004413
    • A.L. Filby, K.L. Thorpe, G. Maack, and C.R. Tyler Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminization in fish Aquat. Toxicol. 81 2007 219 231 (Pubitemid 46216473)
    • (2007) Aquatic Toxicology , vol.81 , Issue.2 , pp. 219-231
    • Filby, A.L.1    Thorpe, K.L.2    Maack, G.3    Tyler, C.R.4
  • 13
    • 84858663629 scopus 로고    scopus 로고
    • Environmental estrogen-induced alterations of male aggression and dominance hierarchies in fish: A mechanistic analysis
    • A.L. Filby, G.C. Paull, F. Searle, M. Ortiz-Zarragoitia, and C.R. Tyler Environmental estrogen-induced alterations of male aggression and dominance hierarchies in fish: a mechanistic analysis Environ. Sci. Technol. 46 2012 3472 3479
    • (2012) Environ. Sci. Technol. , vol.46 , pp. 3472-3479
    • Filby, A.L.1    Paull, G.C.2    Searle, F.3    Ortiz-Zarragoitia, M.4    Tyler, C.R.5
  • 14
    • 0030606153 scopus 로고    scopus 로고
    • Transcriptional and post-transcriptional regulation of rainbow trout estrogen receptor and vitellogenin gene expression
    • DOI 10.1016/S0303-7207(96)03960-3, PII S0303720796039603
    • G. Flouriot, F. Pakdel, and Y. Valotaire Transcriptional and post-transcriptional regulation of rainbow trout estrogen receptor and vitellogenin gene expression Mol. Cell. Endocrinol. 124 1996 173 183 (Pubitemid 27042076)
    • (1996) Molecular and Cellular Endocrinology , vol.124 , Issue.1-2 , pp. 173-183
    • Flouriot, G.1    Pakdel, F.2    Valotaire, Y.3
  • 15
    • 16244419754 scopus 로고    scopus 로고
    • Gene structure, multiple alternative splicing, and expression in gonads of zebrafish Dmrt1
    • DOI 10.1016/j.bbrc.2005.03.066
    • Y. Guo, H. Cheng, X. Huang, S. Gao, H. Yu, and R. Zhou Gene structure, multiple alternative splicing, and expression in gonads of zebrafish Dmrt1 Biochem. Biophys. Res. Commun. 330 2005 950 957 (Pubitemid 40462178)
    • (2005) Biochemical and Biophysical Research Communications , vol.330 , Issue.3 , pp. 950-957
    • Guo, Y.1    Cheng, H.2    Huang, X.3    Gao, S.4    Yu, H.5    Zhou, R.6
  • 17
    • 67650093529 scopus 로고    scopus 로고
    • Changes in the relative expression pattern of multiple vitellogenin genes in adult male and larval zebrafish exposed to exogenous estrogens
    • T.B. Henry, J.T. McPherson, E.D. Rogers, T.P. Heah, S.A. Hawkins, A.C. Layton, and G.S. Sayler Changes in the relative expression pattern of multiple vitellogenin genes in adult male and larval zebrafish exposed to exogenous estrogens Comp. Biochem. Physiol. A 154 2009 119 126
    • (2009) Comp. Biochem. Physiol. A , vol.154 , pp. 119-126
    • Henry, T.B.1    McPherson, J.T.2    Rogers, E.D.3    Heah, T.P.4    Hawkins, S.A.5    Layton, A.C.6    Sayler, G.S.7
  • 18
    • 0038613104 scopus 로고    scopus 로고
    • Developmental estrogenic exposure in zebrafish (Danio rerio): I. Effects on sex ratio and breeding success
    • DOI 10.1016/S0166-445X(02)00207-2
    • R.L. Hill, and D.M. Janz Developmental estrogenic exposure in zebrafish (Danio rerio): I. Effects on sex ratio and breeding success Aquat. Toxicol. 63 2003 417 429 (Pubitemid 36561612)
    • (2003) Aquatic Toxicology , vol.63 , Issue.4 , pp. 417-429
    • Hill Jr., R.L.1    Janz, D.M.2
  • 19
    • 33746740465 scopus 로고    scopus 로고
    • Brain and gonadal aromatase as potential targets of endocrine disrupting chemicals in a model species, the zebrafish (Danio rerio)
    • DOI 10.1002/tox.20203
    • N. Hinfray, O. Palluel, C. Turies, C. Cousin, J.M. Porcher, and F. Brion Brain and gonadal aromatase as potential targets of endocrine disrupting chemicals in a model species, the zebrafish (Danio rerio) Environ. Toxicol. 21 2006 332 337 (Pubitemid 44167704)
    • (2006) Environmental Toxicology , vol.21 , Issue.4 , pp. 332-337
    • Hinfray, N.1    Palluel, O.2    Turies, C.3    Cousin, C.4    Porcher, J.M.5    Brion, F.6
  • 20
    • 0037462269 scopus 로고    scopus 로고
    • Effects of 17a-ethinylestradiol on the expression of three estrogen-responsive genes and cellular ultrastructure of liver and testes in male zebrafish
    • DOI 10.1016/S0166-445X(02)00049-8, PII S0166445X02000498
    • M. Islinger, D. Willimski, A. Völkl, and T. Braunbeck Effects of 17a-ethinylestradiol on the expression of three estrogen-responsive genes and cellular ultrastructure of liver and testes in male zebrafish Aquat. Toxicol. 62 2003 85 103 (Pubitemid 36034321)
    • (2003) Aquatic Toxicology , vol.62 , Issue.2 , pp. 85-103
    • Islinger, M.1    Willimski, D.2    Volkl, A.3    Braunbeck, T.4
  • 21
    • 53649084248 scopus 로고    scopus 로고
    • Hepatic and extrahepatic expression of estrogen-responsive genes in male adult zebrafish (Danio rerio) as biomarkers of short-term exposure to 17β-estradiol
    • Y. Jin, W. Wang, G.D. Sheng, W. Liu, and Z. Fu Hepatic and extrahepatic expression of estrogen-responsive genes in male adult zebrafish (Danio rerio) as biomarkers of short-term exposure to 17β-estradiol Environ. Monit. Assess. 146 2008 105 111
    • (2008) Environ. Monit. Assess. , vol.146 , pp. 105-111
    • Jin, Y.1    Wang, W.2    Sheng, G.D.3    Liu, W.4    Fu, Z.5
  • 22
    • 67650719827 scopus 로고    scopus 로고
    • Induction of estrogen-responsive gene transcription in the embryo, larval, juvenile and adult life stages of zebrafish as biomarkers of short-term exposure to endocrine disrupting chemicals
    • Y. Jin, R. Chen, L. Sun, H. Qian, W. Liu, and Z. Fu Induction of estrogen-responsive gene transcription in the embryo, larval, juvenile and adult life stages of zebrafish as biomarkers of short-term exposure to endocrine disrupting chemicals Comp. Biochem. Physiol. C 150 2009 414 420
    • (2009) Comp. Biochem. Physiol. C , vol.150 , pp. 414-420
    • Jin, Y.1    Chen, R.2    Sun, L.3    Qian, H.4    Liu, W.5    Fu, Z.6
  • 23
    • 61349131321 scopus 로고    scopus 로고
    • Enantioselective induction of estrogen-responsive gene expression by permethrin enantiomers in embryo-larval zebrafish
    • Y. Jin, R. Chen, L. Sun, W. Wang, L. Zhou, W. Liu, and Z. Fu Enantioselective induction of estrogen-responsive gene expression by permethrin enantiomers in embryo-larval zebrafish Chemosphere 74 2009 1238 1244
    • (2009) Chemosphere , vol.74 , pp. 1238-1244
    • Jin, Y.1    Chen, R.2    Sun, L.3    Wang, W.4    Zhou, L.5    Liu, W.6    Fu, Z.7
  • 24
    • 72049099850 scopus 로고    scopus 로고
    • Temperature and photoperiod affect the endocrine disruption effects of ethinylestradiol, nonylphenol and their binary mixture in zebrafish (Danio rerio)
    • Y. Jin, L. Shu, L. Sun, W. Liu, and Z. Fu Temperature and photoperiod affect the endocrine disruption effects of ethinylestradiol, nonylphenol and their binary mixture in zebrafish (Danio rerio) Comp. Biochem. Physiol. C 151 2010 258 263
    • (2010) Comp. Biochem. Physiol. C , vol.151 , pp. 258-263
    • Jin, Y.1    Shu, L.2    Sun, L.3    Liu, W.4    Fu, Z.5
  • 26
    • 39449122159 scopus 로고    scopus 로고
    • Biomarkers for exposure to estrogenic compounds: Gene expression analysis in zebrafish (Danio rerio)
    • DOI 10.1002/tox.20306
    • U. Kausch, M. Alberti, S. Haindl, J. Budczies, and B. Hock Biomarkers for exposure to estrogenic compounds: gene expression analysis in zebrafish (Danio rerio) Environ. Toxicol. 23 2008 15 24 (Pubitemid 351272436)
    • (2008) Environmental Toxicology , vol.23 , Issue.1 , pp. 15-24
    • Kausch, U.1    Alberti, M.2    Haindl, S.3    Budczies, J.4    Hock, B.5
  • 27
    • 2942733417 scopus 로고    scopus 로고
    • Effects of endocrine disrupting chemicals on the expression of CYP19 genes in zebrafish (Danio rerio) juveniles
    • Y. Kazeto, A.R. Place, and J.M. Trant Effects of endocrine disrupting chemicals on the expression of CYP19 genes in zebrafish (Danio rerio) juveniles Aquat. Toxicol. 69 2004 25 34
    • (2004) Aquat. Toxicol. , vol.69 , pp. 25-34
    • Kazeto, Y.1    Place, A.R.2    Trant, J.M.3
  • 28
    • 0035109037 scopus 로고    scopus 로고
    • Distinct cytochrome P450 aromatase isoforms in zebrafish (Danio rerio) brain and ovary are differentially programmed and estrogen regulated during early development
    • DOI 10.1210/en.142.2.740
    • M. Kishida, and G.V. Callard Distinct cytochrome P450 aromatase isoforms in zebrafish (Danio rerio) brain and ovary are differentially programmed and estrogen regulated during early development Endocrinology 142 2001 740 750 (Pubitemid 32222424)
    • (2001) Endocrinology , vol.142 , Issue.2 , pp. 740-750
    • Kishida, M.1    Callard, G.V.2
  • 29
    • 0037085574 scopus 로고    scopus 로고
    • Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams, 1999-2000: A national reconnaissance
    • DOI 10.1021/es011055j
    • D.W. Kolpin, E.T. Furlong, M.T. Meyer, E.M. Thurman, S.D. Zaugg, L.B. Barber, and H.T. Buxton Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. Streams, 1999-2000: A national reconnaissance Environ. Sci. Technol. 36 2002 1202 1211 (Pubitemid 34228893)
    • (2002) Environmental Science and Technology , vol.36 , Issue.6 , pp. 1202-1211
    • Kolpin, D.W.1    Furlong, E.T.2    Meyer, M.T.3    Thurman, E.M.4    Zaugg, S.D.5    Barber, L.B.6    Buxton, H.T.7
  • 31
    • 42749097174 scopus 로고    scopus 로고
    • Male zebrafish (Danio rerio) courtship behaviour resists the feminising effects of 17α-ethinyloestradiol - Morphological sexual characteristics do not
    • M.G. Larsen, K.B. Hansen, P.G. Henriksen, and E. Baatrup Male zebrafish (Danio rerio) courtship behaviour resists the feminising effects of 17α-ethinyloestradiol - morphological sexual characteristics do not Aquat. Toxicol. 87 2008 234 244
    • (2008) Aquat. Toxicol. , vol.87 , pp. 234-244
    • Larsen, M.G.1    Hansen, K.B.2    Henriksen, P.G.3    Baatrup, E.4
  • 32
    • 69049106482 scopus 로고    scopus 로고
    • Reversibility of estrogenic sex changes in zebrafish (Danio Rerio)
    • M.G. Larsen, K. Bilberg, and E. Baatrup Reversibility of estrogenic sex changes in zebrafish (Danio Rerio) Environ. Toxicol. Chem. 28 2009 1783 1785
    • (2009) Environ. Toxicol. Chem. , vol.28 , pp. 1783-1785
    • Larsen, M.G.1    Bilberg, K.2    Baatrup, E.3
  • 33
    • 84895896881 scopus 로고    scopus 로고
    • Ethinyl estradiol and other human pharmaceutical estrogens in the aquatic environment: A review of recent risk assessment data
    • J. Laurenson, R. Bloom, S. Page, and N. Sadrieh Ethinyl estradiol and other human pharmaceutical estrogens in the aquatic environment: a review of recent risk assessment data AAPS J. 16 2014 299 310
    • (2014) AAPS J. , vol.16 , pp. 299-310
    • Laurenson, J.1    Bloom, R.2    Page, S.3    Sadrieh, N.4
  • 34
    • 33646854725 scopus 로고    scopus 로고
    • Endocrine disrupting chemicals (bisphenol A, 4-nonylphenol, 4-tert-octylphenol) modulate expression of two distinct cytochrome P450 aromatase genes differently in gender types of the hermaphroditic fish Rivulus marmoratus
    • DOI 10.1016/j.bbrc.2006.04.137, PII S0006291X06009624
    • Y.-M. Lee, J.S. Seo, I.-C. Kim, Y.-D. Yoon, and J.-S. Lee Endocrine disrupting chemicals (bisphenol A, 4-nonylphenol, 4-tert-octylphenol) modulate expression of two distinct cytochrome P450 aromatase genes differently in gender types of the hermaphroditic fish Rivulus marmoratus Biochem. Biophys. Res. Commun. 345 2006 894 903 (Pubitemid 43776978)
    • (2006) Biochemical and Biophysical Research Communications , vol.345 , Issue.2 , pp. 894-903
    • Lee, Y.-M.1    Seo, J.S.2    Kim, I.-C.3    Yoon, Y.-D.4    Lee, J.-S.5
  • 35
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • K. Livak, and T. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2-DeltaDeltaCT method Methods 25 2001 402 408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 36
    • 8844248618 scopus 로고    scopus 로고
    • Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure
    • G. Maack, and H. Segner Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure Comp. Biochem. Physiol. C 139 2004 47
    • (2004) Comp. Biochem. Physiol. C , vol.139 , pp. 47
    • Maack, G.1    Segner, H.2
  • 37
    • 34547104388 scopus 로고    scopus 로고
    • Microarray analysis in the zebrafish (Danio rerio) liver and telencephalon after exposure to low concentration of 17alpha-ethinylestradiol
    • DOI 10.1016/j.aquatox.2007.05.012, PII S0166445X0700207X
    • C.J. Martyniuk, E.R. Gerrie, J.T. Popesku, M. Ekker, and V.L. Trudeau Microarray analysis in the zebrafish (Danio rerio) liver and telencephalon after exposure to low concentration of 17alpha-ethinylestradiol Aquat. Toxicol. 84 2007 38 49 (Pubitemid 47096745)
    • (2007) Aquatic Toxicology , vol.84 , Issue.1 , pp. 38-49
    • Martyniuk, C.J.1    Gerrie, E.R.2    Popesku, J.T.3    Ekker, M.4    Trudeau, V.L.5
  • 38
    • 43649107450 scopus 로고    scopus 로고
    • Vitellogenin as a biomarker of exposure to estrogenic compounds in aquatic invertebrates: A review
    • DOI 10.1016/j.envint.2007.09.008, PII S0160412007001882
    • V. Matozzo, F. Gagné, M.G. Marin, F. Ricciardi, and C. Blaise Vitellogenin as a biomarker of exposure to estrogenic compounds in aquatic invertebrates: a review Environ. Int. 34 2008 531 545 (Pubitemid 351681916)
    • (2008) Environment International , vol.34 , Issue.4 , pp. 531-545
    • Matozzo, V.1    Gagne, F.2    Marin, M.G.3    Ricciardi, F.4    Blaise, C.5
  • 40
    • 76849103527 scopus 로고    scopus 로고
    • Differential expression of vitellogenin and oestrogen receptor genes in the liver of zebrafish, Danio rerio
    • X. Meng, C. Bartholomew, and J. Craft Differential expression of vitellogenin and oestrogen receptor genes in the liver of zebrafish, Danio rerio Anal. Bioanal. Chem. 396 2010 625 630
    • (2010) Anal. Bioanal. Chem. , vol.396 , pp. 625-630
    • Meng, X.1    Bartholomew, C.2    Craft, J.3
  • 41
    • 3042858947 scopus 로고    scopus 로고
    • Analysis of the estrogen regulation of the zebrafish estrogen receptor (ER) reveals distinct effects of ERα, ERβ1 and ERβ2
    • DOI 10.1677/jme.0.0320975
    • A. Menuet, Y. Le Page, O. Torres, L. Kern, and F. Pakdel Analysis of the estrogen regulation of the zebrafish estrogen receptor (ER) reveals distinct effects of ER, ER1 and ER2 J. Mol. Endocrinol. 2004 975 986 (Pubitemid 38877698)
    • (2004) Journal of Molecular Endocrinology , vol.32 , Issue.3 , pp. 975-986
    • Menuet, A.1    Le Page, Y.2    Torres, O.3    Kern, L.4    Kah, O.5    Pakdel, F.6
  • 43
    • 33646821720 scopus 로고    scopus 로고
    • Adverse effects of the model environmental estrogen diethylstilbestrol are transmitted to subsequent generations
    • R.R. Newbold, E. Padilla-Banks, and W.N. Jefferson Adverse effects of the model environmental estrogen diethylstilbestrol are transmitted to subsequent generations Endocrinology 147 2006 s11 s17
    • (2006) Endocrinology , vol.147
    • Newbold, R.R.1    Padilla-Banks, E.2    Jefferson, W.N.3
  • 44
    • 84876971266 scopus 로고    scopus 로고
    • Impact of environmental estrogens on nucleotide excision repair gene expression in embryonic zebrafish
    • E.G. Notch, and G.D. Mayer Impact of environmental estrogens on nucleotide excision repair gene expression in embryonic zebrafish Comp. Biochem. Physiol. C 157 2013 361 365
    • (2013) Comp. Biochem. Physiol. C , vol.157 , pp. 361-365
    • Notch, E.G.1    Mayer, G.D.2
  • 45
    • 34547886477 scopus 로고    scopus 로고
    • 17α-Ethinylestradiol decreases expression of multiple hepatic nucleotide excision repair genes in zebrafish (Danio rerio)
    • DOI 10.1016/j.aquatox.2007.06.006, PII S0166445X07002342
    • E.G. Notch, D.M. Miniutti, and G.D. Mayer 17α-Ethinylestradiol decreases expression of multiple hepatic nucleotide excision repair genes in zebrafish (Danio rerio) Aquat. Toxicol. 84 2007 301 309 (Pubitemid 47259534)
    • (2007) Aquatic Toxicology , vol.84 , Issue.3 , pp. 301-309
    • Notch, E.G.1    Miniutti, D.M.2    Mayer, G.D.3
  • 46
    • 70249146482 scopus 로고    scopus 로고
    • Long and winding roads: Testis differentiation in zebrafish
    • L. Orban, P.-E. Olsson, and R. Screenivasan Long and winding roads: testis differentiation in zebrafish Mol. Cell. Endocrinol. 312 2009 35 41
    • (2009) Mol. Cell. Endocrinol. , vol.312 , pp. 35-41
    • Orban, L.1    Olsson, P.-E.2    Screenivasan, R.3
  • 47
    • 0142106401 scopus 로고    scopus 로고
    • Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone
    • DOI 10.1016/S0166-445X(03)00177-2
    • S. Örn, H. Holbech, T.H. Madsen, L. Norrgren, and G.I. Petersen Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone Aquat. Toxicol. 65 2003 397 411 (Pubitemid 37267984)
    • (2003) Aquatic Toxicology , vol.65 , Issue.4 , pp. 397-411
    • Orn, S.1    Holbech, H.2    Madsen, T.H.3    Norrgren, L.4    Petersen, G.I.5
  • 49
    • 20444387577 scopus 로고    scopus 로고
    • Characterization and expression pattern of zebrafish anti-Müllerian hormone (amh) relative to sox9a, sox9b, and cyp19a1a, during gonad development
    • A. Rodríguez-Marí, Y.-L. Yan, R.A. BreMiller, C. Wilson, C. Cañestro, and J.H. Postlethwait Characterization and expression pattern of zebrafish anti-Müllerian hormone (amh) relative to sox9a, sox9b, and cyp19a1a, during gonad development Gene Expr. Patterns 5 2005 655
    • (2005) Gene Expr. Patterns , vol.5 , pp. 655
    • Rodríguez-Marí, A.1    Yan, Y.-L.2    Bremiller, R.A.3    Wilson, C.4    Cañestro, C.5    Postlethwait, J.H.6
  • 50
    • 67249139057 scopus 로고    scopus 로고
    • 17α-Ethinylestradiol alters reproductive behaviors, circulating hormones, and sexual morphology in male fathead minnows (Pimephales promelas)
    • J.D. Salierno, and A.S. Kane 17α-Ethinylestradiol alters reproductive behaviors, circulating hormones, and sexual morphology in male fathead minnows (Pimephales promelas) Environ. Toxicol. Chem. 28 2009 953 961
    • (2009) Environ. Toxicol. Chem. , vol.28 , pp. 953-961
    • Salierno, J.D.1    Kane, A.S.2
  • 51
    • 34248679017 scopus 로고    scopus 로고
    • Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio)
    • DOI 10.1016/j.aquatox.2007.03.019, PII S0166445X07001257
    • E.M. Santos, G.C. Paull, K.J.W. Van Look, V.L. Workman, W.V. Holt, R. van Aerle, P. Kille, and C.R. Tyler Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio) Aquat. Toxicol. 83 2007 134 142 (Pubitemid 46766607)
    • (2007) Aquatic Toxicology , vol.83 , Issue.2 , pp. 134-142
    • Santos, E.M.1    Paull, G.C.2    Van Look, K.J.W.3    Workman, V.L.4    Holt, W.V.5    Van Aerle, R.6    Kille, P.7    Tyler, C.R.8
  • 52
    • 34347393939 scopus 로고    scopus 로고
    • Concentration- and time-dependent effects of the synthetic estrogen, 17α-ethinylestradiol, on reproductive capabilities of the zebrafish, Danio rerio
    • DOI 10.1080/15287390701236470, PII 779883207
    • C. Schäfers, M. Teigeler, A. Wenzel, G. Maack, M. Fenske, and H. Segner Concentration- and time-dependent effects of the synthetic estrogen, 17α-ethinylestradiol, on reproductive capabilities of the zebrafish, Danio rerio J. Toxicol. Environ. Health Part A 70 2007 768 779 (Pubitemid 47024166)
    • (2007) Journal of Toxicology and Environmental Health - Part A: Current Issues , vol.70 , Issue.9 , pp. 768-779
    • Schafers, C.1    Teigeler, M.2    Wenzel, A.3    Maack, G.4    Fenske, M.5    Segner, H.6
  • 53
    • 0024594287 scopus 로고
    • Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p- dioxin (TCDD)
    • DOI 10.1016/0892-0362(89)90080-9
    • S.L. Schantz, and R.E. Bowman Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) Neurotoxicol. Teratol. 11 1989 13 19 (Pubitemid 19126501)
    • (1989) Neurotoxicology and Teratology , vol.11 , Issue.1 , pp. 13-19
    • Schantz, S.L.1    Bowman, R.E.2
  • 54
    • 0029941615 scopus 로고    scopus 로고
    • Effects of gestational and lactational exposure to TCDD or coplanar PCBs on spatial learning
    • DOI 10.1016/S0892-0362(96)90033-1
    • S.L. Schantz, B.-W. Seo, J. Moshtaghian, R.E. Peterson, and R.W. Moore Effects of gestational and lactational exposure to TCDD or coplanar PCBs on spatial learning Neurotoxicol. Teratol. 18 1996 305 313 (Pubitemid 26199582)
    • (1996) Neurotoxicology and Teratology , vol.18 , Issue.3 , pp. 305-313
    • Schantz, S.L.1    Seo, B.-W.2    Moshtaghian, J.3    Peterson, R.E.4    Moore, R.W.5
  • 55
    • 84886388402 scopus 로고    scopus 로고
    • Transcriptome alterations in zebrafish embryos after exposure to environmental estrogens and anti-androgens can reveal endocrine disruption
    • V. Schiller, A. Wichmann, R. Kriehuber, C. Schäfers, R. Fischer, and M. Fenske Transcriptome alterations in zebrafish embryos after exposure to environmental estrogens and anti-androgens can reveal endocrine disruption Reprod. Toxicol. 42 2013 210 223
    • (2013) Reprod. Toxicol. , vol.42 , pp. 210-223
    • Schiller, V.1    Wichmann, A.2    Kriehuber, R.3    Schäfers, C.4    Fischer, R.5    Fenske, M.6
  • 56
    • 34548565847 scopus 로고    scopus 로고
    • Estrogen-induced alterations in amh and dmrt1 expression signal for disruption in male sexual development in the zebrafish
    • DOI 10.1021/es070785+
    • R.W. Schulz, J. Bogerd, R. Male, J. Ball, M. Fenske, L.C. Olsen, and C.R. Tyler Estrogen-induced alterations in amh and dmrt1 expression signal for disruption in male sexual development in the zebrafish Environ. Sci. Technol. 41 2007 6305 6310 (Pubitemid 47395018)
    • (2007) Environmental Science and Technology , vol.41 , Issue.17 , pp. 6305-6310
    • Schulz, R.W.1    Bogerd, J.2    Male, R.3    Ball, J.4    Fenske, M.5    Olsen, L.C.6    Tyler, C.R.7
  • 58
    • 33644651006 scopus 로고    scopus 로고
    • Pathways of endocrine disruption during male sexual differentiation and masculinisation
    • DOI 10.1016/j.beem.2005.09.005, PII S1521690X05000722, Endocrine Disrupters
    • R.M. Sharpe Pathways of endocrine disruption during male sexual differentiation and masculinisation Best Pract. Res. Clin. Endocrinol. Metab. 20 2006 91 110 (Pubitemid 43323766)
    • (2006) Best Practice and Research: Clinical Endocrinology and Metabolism , vol.20 , Issue.1 , pp. 91-110
    • Sharpe, R.M.1
  • 59
    • 77953925670 scopus 로고    scopus 로고
    • In search of determinants: Gene expression during gonadal sex differentiation
    • K.R. Siegfried In search of determinants: gene expression during gonadal sex differentiation J. Fish Biol. 76 2010 1879 1902
    • (2010) J. Fish Biol. , vol.76 , pp. 1879-1902
    • Siegfried, K.R.1
  • 60
    • 84864804104 scopus 로고    scopus 로고
    • Testing the effects of ethinylestradiol and of an environmentally relevant mixture of xenoestrogens as found in the Douro River (Portugal) on the maturation of fish gonads - A stereological study using the zebrafish (Danio rerio) as model
    • P. Silva, M.J. Rocha, C. Cruzeiro, F. Malhão, B. Reis, R. Urbatzka, R.A.F. Monteiro, and E. Rocha Testing the effects of ethinylestradiol and of an environmentally relevant mixture of xenoestrogens as found in the Douro River (Portugal) on the maturation of fish gonads - a stereological study using the zebrafish (Danio rerio) as model Aquat. Toxicol. 124-125 2012 1 10
    • (2012) Aquat. Toxicol. , vol.124-125 , pp. 1-10
    • Silva, P.1    Rocha, M.J.2    Cruzeiro, C.3    Malhão, F.4    Reis, B.5    Urbatzka, R.6    Monteiro, R.A.F.7    Rocha, E.8
  • 62
    • 0035883938 scopus 로고    scopus 로고
    • Developmental expression of cytochrome P450 aromatase genes (CPY19a and CYP19b) in zebrafish fry (Danio rerio)
    • DOI 10.1002/jez.1090
    • J.M. Trant, S. Gavasso, J. Ackers, B.-C. Chung, and A.R. Place Developmental expression of cytochrome P450 aromatase genes (CYP19a and CYP19b) in zebrafish fry (Danio rerio) J. Exp. Zool. 290 2001 475 483 (Pubitemid 32930896)
    • (2001) Journal of Experimental Zoology , vol.290 , Issue.5 , pp. 475-483
    • Trant, J.M.1    Gavasso, S.2    Ackers, J.3    Chung, B.-C.4    Place, A.R.5
  • 64
    • 84856567083 scopus 로고    scopus 로고
    • Effects of ethinylestradiol and of an environmentally relevant mixture of xenoestrogens on steroidogenic gene expression and specific transcription factors in zebrafish
    • R. Urbatzka, E. Rocha, B. Reis, C. Cruzeiro, R.A.F. Monteiro, and M.J. Rocha Effects of ethinylestradiol and of an environmentally relevant mixture of xenoestrogens on steroidogenic gene expression and specific transcription factors in zebrafish Environ. Pollut. 164 2012 28 35
    • (2012) Environ. Pollut. , vol.164 , pp. 28-35
    • Urbatzka, R.1    Rocha, E.2    Reis, B.3    Cruzeiro, C.4    Monteiro, R.A.F.5    Rocha, M.J.6
  • 65
    • 0009622286 scopus 로고    scopus 로고
    • Effects of ethynylestradiol on the reproductive physiology in zebrafish (Danio rerio): Time dependency and reversibility
    • DOI 10.1897/1551-5028(2002)021<0767:EOEOTR>2.0.CO;2
    • K. Van den Belt, P.W. Wester, L.T.M. van der Ven, R. Verheyen, and H. Witters Effects of ethynylestradiol on the reproductive physiology in zebrafish (Danio rerio): time dependency and reversibility Environ. Toxicol. Chem. 21 2002 767 775 (Pubitemid 36090384)
    • (2002) Environmental Toxicology and Chemistry , vol.21 , Issue.4 , pp. 767-775
    • Den Belt, K.V.1    Wester, P.W.2    Van Der Ven, L.T.M.3    Verheyen, R.4    Witters, H.5
  • 66
    • 0037941097 scopus 로고    scopus 로고
    • Effects of 17α-ethynylestradiol in a partial life-cycle test with zebrafish (Danio rerio): Effects on growth, gonads and female reproductive success
    • DOI 10.1016/S0048-9697(03)00046-9
    • K. Van den Belt, R. Verheyen, and H. Witters Effects of 17α-ethynylestradiol in a partial life-cycle test with zebrafish (Danio rerio): effects on growth, gonads and female reproductive success Sci. Total Environ. 309 2003 127 137 (Pubitemid 36677575)
    • (2003) Science of the Total Environment , vol.309 , Issue.1-3 , pp. 127-137
    • Van Den Belt, K.1    Verheyen, R.2    Witters, H.3
  • 67
    • 1242318576 scopus 로고    scopus 로고
    • Comparative study on the in vitro/in vivo estrogenic potencies of 17β-estradiol, estrone, 17α-ethynylestradiol and nonylphenol
    • K. Van den Belt, P. Berckmans, C. Vangenechten, R. Verheyen, and H. Witters Comparative study on the in vitro/in vivo estrogenic potencies of 17β-estradiol, estrone, 17α-ethynylestradiol and nonylphenol Aquat. Toxicol. 66 2004 183 195
    • (2004) Aquat. Toxicol. , vol.66 , pp. 183-195
    • Van Den Belt, K.1    Berckmans, P.2    Vangenechten, C.3    Verheyen, R.4    Witters, H.5
  • 68
    • 3042615976 scopus 로고    scopus 로고
    • Xenoestrogenic effects of ethinylestradiol in zebrafish (Danio rerio)
    • DOI 10.1002/tox.20012
    • B.J. Versonnen, and C.R. Janssen Xenoestrogenic effects of ethinylestradiol in zebrafish (Danio rerio) Environ. Toxicol. 19 2004 198 206 (Pubitemid 38811528)
    • (2004) Environmental Toxicology , vol.19 , Issue.3 , pp. 198-206
    • Versonnen, B.J.1    Janssen, C.R.2
  • 69
    • 84863217808 scopus 로고    scopus 로고
    • Brain circuit imprints of developmental 17α-Ethinylestradiol exposure in guppies (Poecilia reticulata): Persistent effects on anxiety but not on reproductive behaviour
    • K. Volkova, N. Reyhanian, A. Kot-Wasik, H. Olsén, I. Porsch-Hällström, and S. Hallgren Brain circuit imprints of developmental 17α-Ethinylestradiol exposure in guppies (Poecilia reticulata): persistent effects on anxiety but not on reproductive behaviour Gen. Comp. Endocrinol. 178 2012 282 290
    • (2012) Gen. Comp. Endocrinol. , vol.178 , pp. 282-290
    • Volkova, K.1    Reyhanian, N.2    Kot-Wasik, A.3    Olsén, H.4    Porsch- Hällström, I.5    Hallgren, S.6
  • 70
    • 27944438485 scopus 로고    scopus 로고
    • Zebrafish sex determination and differentiation: Involvement of FTZ-F1 genes
    • J. von Hofsten, and P.-E. Olsson Zebrafish sex determination and differentiation: Involvement of FTZ-F1 genes Reprod. Biol. Endocrinol. 3 2005 63
    • (2005) Reprod. Biol. Endocrinol. , vol.3 , pp. 63
    • Von Hofsten, J.1    Olsson, P.-E.2
  • 71
    • 19544368157 scopus 로고    scopus 로고
    • Novel steroidogenic factor-1 homolog (ff1d) is coexpressed with anti-Mullerian Hormone (AMH) in zebrafish
    • DOI 10.1002/dvdy.20335
    • J. von Hofsten, A. Larsson, and P.E. Olsson Novel steroidogenic factor-1 homolog (ff1d) is coexpressed with anti-Mullerian hormone (AMH) in zebrafish Dev. Dyn. 233 2005 595 604 (Pubitemid 40734058)
    • (2005) Developmental Dynamics , vol.233 , Issue.2 , pp. 595-604
    • Von Hofsten, J.1    Larsson, A.2    Olsson, P.-E.3
  • 73
    • 23844471566 scopus 로고    scopus 로고
    • Hepatic and extrahepatic expression of vitellogenin genes in the zebrafish, Danio rerio
    • DOI 10.1016/j.gene.2005.03.041, PII S0378111905001848
    • H. Wang, J.T.T. Tan, A. Emelyanov, V. Korzh, and Z. Gong Hepatic and extrahepatic expression of vitellogenin genes in the zebrafish, Danio rerio Gene 356 2005 91 100 (Pubitemid 41178978)
    • (2005) Gene , vol.356 , Issue.1-2 , pp. 91-100
    • Wang, H.1    Tan, J.T.T.2    Emelyanov, A.3    Korzh, V.4    Gong, Z.5
  • 74
    • 0037598881 scopus 로고    scopus 로고
    • Developmental estrogenic exposure in zebrafish (Danio rerio): II. Histological evaluation of gametogenesis and organ toxicity
    • DOI 10.1016/S0166-445X(02)00208-4
    • L.P. Weber, R.L. Hill, and D.M. Janz Developmental estrogenic exposure in zebrafish (Danio rerio): II. Histological evaluation of gametogenesis and organ toxicity Aquat. Toxicol. 63 2003 431 446 (Pubitemid 36561613)
    • (2003) Aquatic Toxicology , vol.63 , Issue.4 , pp. 431-446
    • Weber, L.P.1    Hill Jr., R.L.2    Janz, D.M.3
  • 75
    • 77952878799 scopus 로고    scopus 로고
    • An integrated transcriptomic and proteomic approach characterizing estrogenic and metabolic effects of 17 α-ethinylestradiol in zebrafish (Danio rerio)
    • M.D. Wit, D. Keil, K.v.d Ven, S. Vandamme, E. Witters, and W.D. Coen An integrated transcriptomic and proteomic approach characterizing estrogenic and metabolic effects of 17 α-ethinylestradiol in zebrafish (Danio rerio) Gen. Comp. Endocrinol. 167 2010 190 201
    • (2010) Gen. Comp. Endocrinol. , vol.167 , pp. 190-201
    • Wit, M.D.1    Keil, D.2    Ven V. K, D.3    Vandamme, S.4    Witters, E.5    Coen, W.D.6
  • 76
    • 43149104589 scopus 로고    scopus 로고
    • Exposure to 17[alpha]-ethynylestradiol impairs reproductive functions of both male and female zebrafish (Danio rerio)
    • H. Xu, J. Yang, Y. Wang, Q. Jiang, H. Chen, and H. Song Exposure to 17[alpha]-ethynylestradiol impairs reproductive functions of both male and female zebrafish (Danio rerio) Aquat. Toxicol. 88 2008 1 8
    • (2008) Aquat. Toxicol. , vol.88 , pp. 1-8
    • Xu, H.1    Yang, J.2    Wang, Y.3    Jiang, Q.4    Chen, H.5    Song, H.6
  • 77
    • 43149104589 scopus 로고    scopus 로고
    • Exposure to 17α-ethynylestradiol impairs reproductive functions of both male and female zebrafish (Danio rerio)
    • H. Xu, J. Yang, Y. Wang, Q. Jiang, H. Chen, and H. Song Exposure to 17α-ethynylestradiol impairs reproductive functions of both male and female zebrafish (Danio rerio) Aquat. Toxicol. 88 2008 1 8
    • (2008) Aquat. Toxicol. , vol.88 , pp. 1-8
    • Xu, H.1    Yang, J.2    Wang, Y.3    Jiang, Q.4    Chen, H.5    Song, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.