Xenoestrogenic effects of ethinylestradiol in zebrafish (Danio rerio)

Environmental Toxicology

Volumn 19, Issue 3, 2004, Pages 198-206

  Versonnen, Bram J ^a   Janssen, Colin R ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Endocrine disruption; Estradiol; Ethinylestradiol; Fish; SDS PAGE; Toxicity; Vitellogenin; Zebrafish

Indexed keywords

ALCOHOLS; APPROXIMATION THEORY; ELECTROPHORESIS; FISHERIES; HORMONES; MOLECULAR WEIGHT; PROTEINS;

EMBRYOS; ESTROGENIC EFFECTS;

ENVIRONMENTAL IMPACT;

ETHINYLESTRADIOL; VITELLOGENIN;

DEVELOPMENTAL STAGE; FISH; HORMONE; POLLUTION EFFECT; TOXICITY;

ANIMAL TISSUE; ARTICLE; BODY GROWTH; BODY HEIGHT; BODY WEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ELECTROPHORESIS; EMBRYO; ESTROGEN ACTIVITY; HATCHING; HOMOGENATE; JUVENILE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; SURVIVAL; TOXICITY; WESTERN BLOTTING; ZEBRA FISH;

AGE FACTORS; ANIMALS; BIOMETRY; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, NONMAMMALIAN; ESTROGENS; ETHINYL ESTRADIOL; FEMALE; LARVA; LIFE CYCLE STAGES; MALE; MOLECULAR WEIGHT; MORTALITY; SEX FACTORS; VITELLOGENINS; XENOBIOTICS; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO; DANIO RERIO;

EID: 3042615976     PISSN: 15204081     EISSN: None     Source Type: Journal    
DOI: 10.1002/tox.20012     Document Type: Article

References (48)

1. Allen Y, Scott AP, Matthiessen P, Haworth S, Thain JE, Feist S. 1999. Survey of estrogenic activity in United Kingdom estuarine and coastal waters and its effects on gonadal development of the flounder Platichthys flesus. Environ Toxicol Chem 18:1791-1800.
2. Allner B, Wegener G, Knacker T, Stahlschmidt-Allner P. 1999. Electrophoretic determination of estrogen-induced protein in fish exposed to synthetic and naturally occurring chemicals. Sci Tot Environ 233:21-31
3. Andersen HR, Andersson AM, Arnold SF, Autrup H, Barfoed M, Beresford NA, Bjerregaard P, Christiansen LB, Gissel B, Hummel R, Jorgensen EB, Korsgaard B, Le Guevel R, Leffers H, McLachlan J, Moller A, Nielsen JB, Olea N, Oles-Karasko A, Pakdel F, Pedersen KL, Perez P, Skakkeboek NE, Sonnenschein C, Soto AM, Sumpter JP, Thorpe SM, Grandjean P. 1999. Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals. Environ Health Perspect 107: 89-108.
4. Andersen L, Bengtsson B, Björk M, Gessbo A, Holbech H, Hylland K, Norrgren L, Pedersen KL, Lundgren A, Petersen GI, Steinholz A, Örn S. Zebra fish for testing endocrine disrupting chemicals. TemaNord 2000/555. Final Report. Nordic Council of Ministers, Copenhagen, Denmark.
5. Andersen L, Holbech H, Gessbo A, Norrgren L, Petersen GI. 2003. Effects of exposure to 17α-ethinylestradiol during early development on sexual differentiation and induction of vitellogenin in zebrafish (Danio rerio). Comp Biochem Phys C Toxicol Pharmacol 134:365-374.
6. 2. Am J Physiol Reg 276:505-513.
7. Brion F, Nilsen BM, Eidem JK, Goksøyr A, Porcher JM. 2002. Development and validation of an enzyme-linked immunosorbent assay to measure vitellogenin in the zebrafish (Danio rerio). Environ Toxicol Chem 28:1699-1708.
8. Christiansen T, Korsgaard B, Jespersen A. 1998. Induction of vitellogenin synthesis by nonylphenol and 17 beta-estradiol and effects on the testicular structure in the eelpout Zoarces viviparus. Mar Environ Res 46:141-144.
9. Desbrow C, Routledge EJ, Brighty GC, Sumpter JP, Waldock M. 1998. Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening. Environ Sci Technol 31:1549-1558.
10. Eaton R, Farley R. 1974. Growth and reduction of depensation of zebra fish, Brachydanio rerio, reared in the laboratory. Copeia 1:204-209.
11. Fenske M, Van Aerle R, Brack S, Tyler CS, Segner H. 2001. Development and validation of a homologous zebrafish (Danio rerio Hamilton-Buchanan) vitellogenin enzyme-linked immunosorbent assay (ELISA) and its application for studies on estrogenic chemicals. Comp Biochem Phys C Toxicol Pharmacol 129:217-232.
12. Harries JE, Runnalls T, Hill E, Harris CA, Maddix S, Sumpter JP, Tyler CR. 2000. Development of a reproductive performance test for endocrine disrupting chemicals using pair-breeding fathead minnows (Pimephales promelas). Environ Sci Technol 34:3003-3011.
13. Henry TR, Spitsbergen JM, Hornung MW, Abnet CC, Peterson RE. 1997. Early life stage toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish (Danio rerio). Toxicol Appl Pharmacol 142:56-68.
14. Heppell SA, Denslow ND, Folmar LC, Sullivan CV. 1995. Universal assay for vitellogenin as a biomarker for environmental estrogens. Environ Health Perspec 103:9-15.
15. Holbech H, Andersen L, Petersen GI, Korsgaard B, Pedersen KL, Bjerregaard P. 2001. Development of an ELISA for vitellogenin in whole body homogenate of zebrafish (Danio rerio). Comp Biochem Phys C Toxicol Pharmacol 130:119-131.
16. Kime DE, Nash JP. 1999. Gamete viability as an indicator of reproductive endocrine disruption in fish. Sci Total Environ 233:123-129.
17. Kinnberg K, Korsgaard B, Bjerregaard P, Jespersen A. 2000. Effects of nonylphenol and 17 beta-estradiol on vitellogenin synthesis and testis morphology in male platyfish Xiphophorus maculatus. J Exp Biol 203:171-181.
18. Kishida M, McLellan M, Miranda JA, Callard GV. 2001. Estrogen and xenoestrogens upregulate the brain aromatase isoform (P450aromB) and perturb markers of early development in zebrafish (Danio rerio). Comp Biochem Phys B Biochem Mol Biol 129:261-268.
19. Kramer VJ, Miles-Richardson S, Pierens SL, Giesy JP. 1998. Reproductive impairment and induction of alkaline-labile phosphatase, a biomarker of estrogen exposure, in fathead minnows (Pimephales promelas) exposed to waterborne 17 beta-estradiol. Aquat Toxicol 40:335-360.
20. Larsson DGJ, Adolfsson-Erici M, Parkkonen J, Petterson M, Berg AH, Olsson P, Förlin L. 1999. Ethinyloestradiol - an undesired fish contraceptive. Aquat Toxicol 45:91-97.
21. Legler J, Broekhof JLM, Brouwer A, Lanser PH, Murk AJ, Van der Saag PT, Vethaak AD, Wester P, Zivkovic D, Van der Burg B. 2000. A novel in vivo bioassay for (xeno)estrogens using transgenic zebrafish. Environ Sci Technol 34:4439-4444.
22. Legler J, Zeinstra LM, Schuitemaker F, Lanser PH, Bogerd J, Brouwer A, Vethaak AD, De Voogt P, Murk AJ, Van der Burg B. 2002. Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity. Environ Sci Technol 36:4410-4415.
23. Mantovani A, Stazi AV, Macri C, Maranghi F, Ricciardi C. 1999. Problems in testing and risk assessment of endocrine disrupting chemicals with regard to developmental toxicology. Chemosphere 39:1293-1300.
24. Mellanen P, Soimasuo M, Holmbom B, Oikari A, Santti R. 1999. Expression of the vitellogenin gene in the liver of juvenile whitefish (Coregonus lavaretus L. s.l.) exposed to effluents from pulp and paper mills. Ecotox Environ Saf 43:133-137.
25. Metscher BD, Ahlberg PE. 1999. Zebratish in context: uses of a laboratory model in comparative studies. Dev Biol 210:1-14.
26. Nichols KM, Snyder EM, Snyder SA, Pierens SL, Miles-Richardson SR, Giesy JP. 2001. Effects of nonylphenol ethoxylate exposure on reproductive output and bioindicators of environmental estrogen exposure in fathead minnows, Pimephales promelas. Environ Toxicol Chem 20:510-522.
27. Panter GH, Hutchinson TH, Lange R, Lye CM, Sumpter JP, Zerulla M, Tyler CR. 2002. Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances. Environ Toxicol Chem 21:319-326.
28. Papoulias DM, Noltie DB, Tillitt DE. 1999. An in vivo model fish system to test chemical effects on sexual differentiation and development: exposure to ethinyl estradiol. Aquat Toxicol 48: 37-50.
29. Purdom CE, Hardiman PA, Bye VJ, Eno NC, Tyler CR, Sumpter JP. 1994. Estrogenic effects of effluents from sewage treatment works. Chem Ecol 8:275-285.
30. Ren L, Lattier D, Lech JJ. 1996. Estrogenic activity in rainbow trout determined with a new cDNA probe for vitellogenesis, pSG5V1.1. B Environ Contam Tox 56:287-294.
31. Rose J, Holbech H, Lindholst C, Nørum U, Povlsen A, Korsgaard B, Bjerregaard P (2002). Vitellogenin induction by 17β-estradiol and 17α-ethinylestradiol in male zebrafish (Danio rerio). Comp Biochem Phys C Toxicol Pharmacol 131:531-539.
32. Scholz S, Gutzeit HO. 2000. 17-α-ethinylestradiol affects reproduction, sexual differentiation and aromatase gene expression of the medaka (Oryzias latipes). Aquat Toxicol 50:363-373.
33. Seki M, Yokota H, Matsubara H, Tsuruda Y, Maeda N, Tadokoro H, Kobayashi K. 2002. Effect of ethinylestradiol on the reproduction and induction of vitellogenin and testis-ova in medaka (Oryzias latipes). Environ Toxicol Chem 21:1692-1698.
34. Selman K, Wallace RA, Sarka A. 1993. Stages of oocyte development in the zebrafish, Brachydanio rerio. J Morphol 218: 203-224.
35. Sole M., Porte C., Barcelo D. 2000. Vitellogenin and other biochemical responses in carp, Cyprinus carpio, after experimental injection with 17 alpha-ethynylestradiol. Arch Environ Contam Toxicol 38:494-500.
36. Ternes TA, Stumpf M, Mueller J, Haberer K Wilken RD, Servos M. 1999. Behavior and occurrence of estrogens in municipal sewage treatment plants. I. Investigations in Germany, Canada and Brazil. Sci Tot Environ 225:81-90.
37. Tilton F, Benson WH, Schlenk D. 2001. Elevation of serum 17-β-estradiol in channel catfish following injection of 17-β-estradiol, ethynyl estradiol, estrone, estriol and estradiol-17-β-glucoronide. Environ Toxicol Pharmacol 9:169-172.
38. Tyler CR, Routledge EJ. 1998. Oestrogenic effects in fish in English rivers with evidence of their causation. Pure Appl Chem 70:1795-1804.
39. Tyler CR, Van Aerle R, Hutchinson TH, Maddix S, Trip H. 1999. An in vivo testing system for endocrine disruptors in fish early life stages using induction of vitellogenin. Environ Toxicol Chem 18:337-347.
40. Tyler CR, Van der Eerden B, Jobling S, Panter G, Sumpter JP. 1996. Measurement of vitellogenin, a biomarker for exposure to oestrogenic chemicals, in a wide variety of cyprinid fish. J Comp Physiol B Biochem Syst Environ Physiol 166:418-426.
41. Van den Belt K, Verheyen R, Witters H. 2001. Reproductive effects of ethynylestradiol and 4t-octylphenol on the zebrafish (Danio rerio). Arch Environ Contam Toxicol 41:458-467.
42. Van den Belt K, Wester P, van der Ven L, Verheyen R, Witters H. 2002. Effects of ethynylestradiol on the reproductive physiology in zebrafish (Danio rerio): time dependency and reversibility. Environ Toxicol Chem 21:767-775.
43. Van Leeuwen CJ, Griffioen PS, Vergouw WHA, Maas-Diepeveen JL. 1985. Differences in susceptibility of early life stages of rainbow trout (Salmo gairdneri) to environmental pollutants. Aquat Toxicol 7:59-78.
44. Versonnen BJ, Arijs K, Verslycke T, Lema W, Janssen CR. 2003. In vitro and in vivo estrogenicity and toxicity of o-, m- and p-dichlorobenzene. Environ Toxicol Chem 22:329-335.
45. Wang H, Yan T, Tan JTT, Gong Z. 2000. A zebrafish vitellogenin gene (vg3) encodes a novel vitellogenin without a phosvitin domain and may represent a primitive vertebrate vitellogenin gene. Gene, 256:303-310.
46. Westerfield M. 1995. The zebrafish book, guide for the laboratory use of zebrafish (Danio rerio). Eugene, OR: University of Oregon Press.
47. Yokota H, Seki M, Maeda M, Oshima Y, Tadokoro H, Honjo T, Kobayashi K. 2001. Life-cycle toxicity of 4-nonylphenol to medaka (Oryzias latipes). Environ Toxicol Chem 20:2552-2560.
48. Zillioux EJ, Johnson IC, Kiparissis Y, Metcalfe CD, Wheat JV, Ward SG, Liu H. 2001. The sheepshead minnow as an in vivo model for endocrine disruption in marine teleosts: a partial life-cycle test with 17α-ethynylestradiol. Environ Toxicol Chem 20:1968-1978.