Comparative study on the in vitro/in vivo estrogenic potencies of 17β-estradiol, estrone, 17α-ethynylestradiol and nonylphenol

Aquatic Toxicology

Volumn 66, Issue 2, 2004, Pages 183-195

  Van Den Belt, K ^a   Berckmans, P ^a   Vangenechten, C ^a   Verheyen, R ^a   Witters, H ^a  

^a FLEMISH INSTITUTE FOR TECHNOLOGICAL RESEARCH VITO   (Belgium)

Author keywords

17 Ethynylestradiol; 17 Estradiol; Cellular assays; Estrone; Fish

Indexed keywords

ALKYLPHENOL; BIOLOGICAL MARKER; ESTRADIOL; ESTROGEN RECEPTOR; ESTRONE; ETHINYLESTRADIOL; NONYLPHENOL; VITELLOGENIN;

CHEMICAL POLLUTANT; COMPARATIVE STUDY; DOSE-RESPONSE RELATIONSHIP; ESTROGENIC COMPOUND; FISH;

ARTICLE; CANCER CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; NONHUMAN; OVARY FUNCTION; PRIORITY JOURNAL; YEAST; ZEBRA FISH;

DANIO; DANIO RERIO;

EID: 1242318576     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2003.09.004     Document Type: Article

References (39)

1. Ankley G., Mihaich E., Stahl R., Tillitt D., Colborn T., MacMaster S., Miller R., Bantle J., Campbell P., Denslow N., Dickerson R., Folmar L., Fry M., Giesy J., Gray E.L., Guiney P., Hutchinson T., Kennedy S., Kramer V., LeBlanc G., Mayes M., Nimrod A., Patino R., Petersen R., Purdy R., Ringer R., Thoams P., Touart L., Van Der Kraak G., Zacharewski T. Overview of a workshop on screening methods for detecting potential (anti) estrogenic/androgenic chemicals in wildlife. Environ. Toxicol. Chem. 17:1998;68-87.
2. Arcand-Hoy L.L., Benson W.H. Fish reproduction, an ecologically relevant indicator of endocrine disruption. Environ. Toxicol. Chem. 17:1998;49-57.
3. Brouwer A., Reijnders P.J.H., Koeman J.H. Polychlorinated biphenyl (PCB)-contaminated fish induces vitamin A and thyroid deficiency in the common seal (Phoca vitulina). Aquat. Toxicol. 15:1989;99-106.
4. Bun Ng, T., Idler, D.R., 1983. Yolk formation and differentiation in teleost fishes. In: Hoar, W.S., Randall, D.J. (Eds.), Fish Physiology, vol. IXA. Academic Press, USA, pp. 373-397.
5. Coldham N.G., Mehul D., Sivapathasundaram S., McDonnell D.P., Conor C., Sauer M.J. Evaluation of a recombinant yeast cell estrogen screening assay. Environ. Health Perspect. 105:1997;734-742.
6. Desbrow C., Routledge E.J., Brighty G.C., Sumpter J.P., Waldock M. Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening. Environ. Sci. Technol. 32:1998;1549-1558.
7. EDSTAC, 2000. Report to Congress. Endocrine Disrupting Screening Program-Environmental Protection Agency.
8. EMWAT, 1997. In: Tattersfield, L., Matthiesssen, P., Campbell, P., Grandy, N., Länge, R. (Eds)., SETAC-Europe, OECD, EC Expert Workshop on Endocrine Modulators and Wildlife: Assessment and Testing, Veldhoven, The Netherlands, 10-13 April 1997. SETAC-Europe, Brussels, Belgium, p. 126.
9. Folmar, L.C., Denslow, N.D., Rao, V., Chow, M., Crain, A., Enblom, J., Marcino, J., Guillette Jr. L.J., 1996. Vitellogenin inductions and reduced serum testosteron concentrations in feral male carp (Cyprinus carpio) captured near a major metropolitan sewage treatment plant, Environ. Health Perspect. 104, 1096-1101.
10. Fry D.M. Reproductive effects in birds exposed to pesticides and industrial chemicals. Environ. Health Perspect. 103(Suppl. 7):1995;165-171.
11. Guengerich F.P. Metabolism of 17α-ethynylestradiol in humans. Life Sci. 47:1990;1981-1988.
12. Guillette L.J., Gross T.S., Mason G.R., Matter J.M., Percival H.F., Wood-ward A.R. Developmental abnormalities of the gonads and abnormal sex-hormone concentrations in juvenile alligators from contaminated and control lakes in Florida. Environ. Health Perspect. 102:1994;680-688.
13. Jobling S., Sheanan D., Osborne J.A., Matthiesen P., Sumpter J.P. Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed to alkylphenolic chemicals. Environ. Toxicol. Chem. 15:1996;194-202.
14. Khim J.S., Lee k.T., Villeneuve D.L., Kannan K., Giesy J.P., Koh C.H. In vitro bioassay determination of dioxin-like and estrogenic activity in sediment and water from Ulsan bay and its vicinity, Korea. Arch. Environ. Contam. Toxicol. 40:2001;151-160.
15. Klotz D.M., Beckman B.S., Hill S.M., McLachlan J.A., Walters M.R., Arnold S.F. Identification of environmental chemicals with estrogenic activity using a combination of in vitro assays. Environ. Health Perspect. 104(Suppl. 10):1996;1084-1089.
16. Kramer V.J., Miles-Richardson S., Pierens S.L., Giesy J.P. Reproductive impairment and induction of alkaline-labile phosphate, a biomarker of estrogen exposure, in fathead minnows (Pimephales promelas) exposed to waterborne 17β-estradiol. Aquat. Toxicol. 40:1998;335-360.
17. Legler J., van den Brink C.E., Brouwer A., Murk A.J., van der Saag P.T., Vethaak A.D., van der Burg B. Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line. Toxicol. Sci. 48:1999;55-66.
18. Legler J., Zeinstra L.M., Schuitemaker F., Lanser P.H., Bogerd J., Brouwer A., Vethaak A.D., De Voogt P., Murk A.J., van der Burg B. Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity. Environ. Sci. Technol. 36(20):2002;4410-4415.
19. Lyle C.M., Frid C.L.J., Gill M.E., McCormick D. Abnormalities in the reproductive health of flounder Platichthyus flesus exposed to effluent from a sewage treatment works. Mar. Pollut. Bull. 34:1997;34-41.
20. Miles-Richardson S.R., Kramer V.J., Fitzgerald S.D., Render J.A., Yamini B., Barbee S.J., Giesy J.P. Effects of waterborn exposure of 17-β estradiol on secondary sex characteristics and gonads of fathead minnows (Pimephales promelas). Aquat. Toxicol. 47:1999;129-145.
21. Munkittrick K.R., Portt C.B., Van Der Kraak G.J., Smith I.R., Rokosh D.A. Impact of bleached kraft mill effluent on population characteristics, liver MFO activity and serum steroid levels of a lake Superior white sucker (Catostomus commersoni) population. Can. J. Fish Aquat. Sci. 48:1991;1371-1380.
22. Nimrod A.C., Benson W.H. Xenobiotic interaction with and alteration of channel catfish estrogen receptor. Toxicol. Appl. Pharmacol. 147:1997;381-390.
23. Örn S., Andersson P.L., Förlin L., Tysklind M., Norrgren L. The impact on reproduction of an orally administered mixture of selected PCBs in zebrafish (Danio rerio). Arch. Environ. Contam. Toxicol. 35:1998;52-57.
24. Panter G.H., Thompson R.S., Sumpter J.P. Adverse reproductive effects in male fathead minnows (Pimephales promelas) exposed to environmentally relevant concentrations of the natural oestrogens, oestradiol and oestrone. Aquat. Toxicol. 42:1998;243-253.
25. Pons M., Gagne D., Nicolas J.C., Mehtali R. A new cellular model of response to estrogens: a bioluminescent test to characterize (anti)estrogen molecules. Biotechnology. 9:1990;450-459.
26. Routledge E.J., Sumpter J.P. Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen. Environ. Toxicol. Chem. 15:1996;241-248.
27. Sheehan D.M., Willingham E., Gaylor D., Bergeron J.M., Crews D. No threshold dose for estradiol-induced sex reversal of turtle embryos: how little is too much? Environ. Health Perspect. 107:1999;155-159.
28. Soto A.M., Sonnenschein C., Chung K.L., Fernandez M.F., Olea N., Serrano F.O. The E-screen assay as a tool to identify estrogens an update on estrogenic environmental pollutants. Environ. Health Perspect. 103(Suppl. 7):1995;113-122.
29. Sumpter J.P., Jobling S. Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. Environ. Health Perspect. 103(Suppl. 7):1995;173-178.
30. Ternes T.A., Stumph M., Mueller J., Haberer K., Wilken R.D., Servos M. Behavior and occurrence of estrogens in municipal sewage treatment plants. I. Investigations in Germany, Canada and Brazil. Sci. Total Environ. 225:1999a;81-90.
31. Ternes T.A., Kreckel P., Mueller J. Behavior and occurrence of estrogens in municipal sewage treatment plants. II. Aerobic batch experiments with activated sludge. Sci. Total Environ. 225:1999b;91-99.
32. Thorpe K.L., Hutchinson T.H., Hetheridge M.J., Sumpter J.P., Tyler C.R. Development of an in vivo screening assay for estrogenic chemicals using juvenile rainbow trout (Oncorhynchus mykiss). Environ. Toxicol. Chem. 19:2000;2812-2820.
33. Tyler C.R., van der Eerden B., Jobling S., Panter G., Sumpter J.P. Measurement of vitellogenin, a biomarker for exposure to oestrogenic chemicals, in a wide variety of cyprinid fish. J. Comp. Physiol. B. 166:1996;418-426.
34. Tyler C., Jobling S., Sumpter J.P. Endocrine disruption in wildlife: a critical review of the evidence. Crit. Rev. Toxicol. 28:1998;319-363.
35. Van den Belt K., Verheyen R., Witters H. Reproductive effects of ethynylestradiol and 4t-octylphenol on the zebrafish (Danio rerio). Arch. Environ. Contam. 41(4):2001;458-467.
36. Van den Belt K., Wester P., van der Van L., Verheyen R., Witters H. Effects of ethynylestradiol on the reproductive physiology in zebrafish (Danio rerio): time dependency and reversibility. Environ. Toxicol. Chem. 21(4):2002;767-775.
37. Van den Belt K., Verheyen R., Witters H. Comparison of vitellogenin responses in zebrafish and rainbow trout following exposure to environmental estrogens. Ecotoxicol. Environ. Safety. 56(2):2003;271-281.
38. Witters H., Vangenechten C., Berckmans P. Detection of estrogenic activity in Flemish surface waters using a in vitro recombinant assay with yeast cells. Wat. Sci. Technol. 43:2001;117-123.
39. Zacharewski T. In vitro bioassays for estrogenic substances. Environ. Sci. Technol. 31:1997;613-623.