Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levels

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Ristau, Tina ^a   Paun, Constantin ^b   Ersoy, Lebriz ^a   Hahn, Moritz ^c   Lechanteur, Yara ^b   Hoyng, Carel ^b   De Jong, Eiko K ^b   Daha, Mohamed R ^d   Kirchhof, Bernd ^a   Den Hollander, Anneke I ^b   Fauser, Sascha ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF COLOGNE   (Germany)

^d LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3D; COMPLEMENT FACTOR H; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE;

ADULT; AGED; ARTICLE; BODY MASS; CATABOLISM; COHORT ANALYSIS; COMPLEMENT SYSTEM; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HEREDITY; HUMAN; MALE; PHENOTYPE; RETINA IMAGE; RETINA MACULA AGE RELATED DEGENERATION; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; VERY ELDERLY; VISUAL IMPAIRMENT; AGE; ALLELE; BIOLOGICAL MODEL; COMPLEMENT ACTIVATION; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MACULAR DEGENERATION; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; RISK FACTOR;

AGE FACTORS; AGED; AGED, 80 AND OVER; ALLELES; COMPLEMENT ACTIVATION; COMPLEMENT C3D; COMPLEMENT FACTOR B; COMPLEMENT FACTOR H; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MACULAR DEGENERATION; MALE; MIDDLE AGED; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SMOKING;

EID: 84899863640     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093459     Document Type: Article

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