pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: Involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1)

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Radhakrishnan, Vijayababu M ^a   Kojs, Pawel ^b   Young, Gavin ^c   Ramalingam, Rajalakshmy ^a   Jagadish, Bhumasamudram ^c,d   Mash, Eugene A ^c,d   Martinez, Jesse D ^c   Ghishan, Fayez K ^a   Kiela, Pawel R ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b Department of Nutritional Sciences ^*  (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTACTIN; CURCUMIN; MESSENGER RNA; PROTEIN P120; PROTEIN TYROSINE PHOSPHATASE 1B; TYROSINE; ANTINEOPLASTIC AGENT; CATENIN; DELTA CATENIN; PROTEIN BINDING; PTPN1 PROTEIN, HUMAN;

ARTICLE; BINDING AFFINITY; BIOTINYLATION; CELL MIGRATION; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORTACTIN GENE; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; GENE EXPRESSION; HCT116 CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; WESTERN BLOTTING; ADENOCARCINOMA; CELL MEMBRANE; CELL MOTION; COLORECTAL TUMOR; CONFOCAL MICROSCOPY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CATENINS; CELL LINE, TUMOR; CELL MEMBRANE; CELL MOVEMENT; COLORECTAL NEOPLASMS; CORTACTIN; CURCUMIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HT29 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, CONFOCAL; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TYROSINE;

EID: 84899855799     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085796     Document Type: Article

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