Mannose binding lectin and susceptibility to rheumatoid arthritis in Brazilian patients and their relatives

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Goeldner, Isabela ^a,b   Skare, Thelma L ^c   Utiyama, Shirley R ^a   Nisihara, Renato M ^a   Tong, Hoang Van ^b   Messias Reason, Iara J T ^a   Velavan, Thirumalaisamy P ^b,d  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c University Evangelic Hospital   (Brazil)

^d Fondation Congolaise Pour la Recherche Medicale   (Congo)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC CITRULLINATED PEPTIDE ANTIBODY; MANNOSE BINDING LECTIN; MANNOSE BINDING LECTIN 2; RHEUMATOID FACTOR; MBL2 PROTEIN, HUMAN;

5' UNTRANSLATED REGION; ADULT; AGED; ARTICLE; BRAZIL; CONTROLLED STUDY; DISEASE DURATION; EXON; FEMALE; FUNCTIONAL STATUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MBL2 GENE; ONSET AGE; PROMOTER REGION; PROTEIN BLOOD LEVEL; RELATIVE; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; SJOEGREN SYNDROME; ADOLESCENT; ALLELE; BLOOD; CASE CONTROL STUDY; CHILD; COHORT ANALYSIS; DISEASE PREDISPOSITION; FAMILY; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; ARTHRITIS, RHEUMATOID; BRAZIL; CASE-CONTROL STUDIES; CHILD; COHORT STUDIES; DISEASE SUSCEPTIBILITY; FAMILY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; MANNOSE-BINDING LECTIN; MIDDLE AGED; YOUNG ADULT;

EID: 84899853417     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095519     Document Type: Article

References (64)

1. Bansback N, Marra CA, Finckh A, Anis A (2009) The economics of treatment in early rheumatoid arthritis. Best Pract Res Clin Rheumatol 23: 83-92.
2. Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, et al. (2010) 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 62: 2569-2581.
3. MacGregor AJ, Snieder H, Rigby AS, Koskenvuo M, Kaprio J, et al. (2000) Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum 43: 30-37. (Pubitemid 30368210)
4. McInnes IB, Schett G (2011) The pathogenesis of rheumatoid arthritis. N Engl J Med 365: 2205-2219.
5. Wordsworth P, Bell J (1991) Polygenic susceptibility in rheumatoid arthritis. Ann Rheum Dis 50: 343-346.
6. Goeldner I, Skare TL, de Messias Reason IT, Nisihara RM, Silva MB, et al. (2010) Anti-cyclic citrullinated peptide antibodies and rheumatoid factor in rheumatoid arthritis patients and relatives from Brazil. Rheumatology (Oxford) 49: 1590-1593.
7. Goeldner I, Skare TL, de Messias Reason IT, Nisihara RM, Silva MB, et al. (2011) Association of anticyclic citrullinated peptide antibodies with extra-articular manifestations, gender, and tabagism in rheumatoid arthritis patients from southern Brazil. Clin Rheumatol 30: 975-980.
8. Hemminki K, Li X, Sundquist K, Sundquist J (2009) Shared familial aggregation of susceptibility to autoimmune diseases. Arthritis Rheum 60: 2845-2847.
9. Runza VL, Schwaeble W, Mannel DN (2008) Ficolins: novel pattern recognition molecules of the innate immune response. Immunobiology 213: 297-306. (Pubitemid 351479859)
10. Carroll MV, Sim RB (2011) Complement in health and disease. Adv Drug Deliv Rev 63: 965-975.
11. Assaf A, Hoang TV, Faik I, Aebischer T, Kremsner PG, et al. (2012) Genetic evidence of functional ficolin-2 haplotype as susceptibility factor in cutaneous leishmaniasis. PLoS One 7: e34113.
12. Hoang TV, Toan NL, Song lH, Ouf EA, Bock CT, et al. (2011) Ficolin-2 levels and FCN2 haplotypes influence hepatitis B infection outcome in Vietnamese patients. PLoS One 6: e28113.
13. Luz PR, Boldt AB, Grisbach C, Kun JF, Velavan TP, et al. (2013) Association of L-ficolin levels and FCN2 genotypes with chronic Chagas disease. PLoS One 8: e60237.
14. Ouf EA, Ojurongbe O, Akindele AA, Sina-Agbaje OR, van TH, et al. (2012) Ficolin-2 levels and FCN2 genetic polymorphisms as a susceptibility factor in schistosomiasis. J Infect Dis 206: 562-570.
15. Ricklin D, Hajishengallis G, Yang K, Lambris JD (2010) Complement: a key system for immune surveillance and homeostasis. Nat Immunol 11: 785-797.
16. Degn SE, Jensenius JC, Thiel S (2011) Disease-causing mutations in genes of the complement system. Am J Hum Genet 88: 689-705.
17. Heitzeneder S, Seidel M, Forster-Waldl E, Heitger A (2012) Mannan-binding lectin deficiency - Good news, bad news, doesn't matter? Clin Immunol 143: 22-38.
18. Chen M, Daha MR, Kallenberg CG (2010) The complement system in systemic autoimmune disease. J Autoimmun 34: J276-J286.
19. Magorivska I, Jeremic I, Herman S, Munoz LE, Bilyy R, et al. (2014) 1.58 rheumatoid factor binding is influenced by the N-Glycans of their IGG targets. Ann Rheum Dis 73 Suppl 1: A25.
20. Troelsen LN, Jacobsen S, Abrahams JL, Royle L, Rudd PM, et al. (2012) IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis. J Rheumatol 39: 463-469.
21. Troelsen LN, Jacobsen S, Abrahams JL, Royle L, Rudd PM, et al. (2012) IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis. J Rheumatol 39: 463-469.
22. Boldt AB, Goeldner I, de Messias-Reason IJ (2012) Relevance of the lectin pathway of complement in rheumatic diseases. Adv Clin Chem 56: 105-153.
23. Sato R, Matsushita M, Miyata M, Sato Y, Kasukawa R, et al. (1997) Substances reactive with mannose-binding protein (MBP) in sera of patients with rheumatoid arthritis. Fukushima J Med Sci 43: 99-111.
24. Troelsen LN, Garred P, Christiansen B, Torp-Pedersen C, Christensen IJ, et al. (2010) Double role of mannose-binding lectin in relation to carotid intima-media thickness in patients with rheumatoid arthritis. Mol Immunol 47: 713-718.
25. Saevarsdottir S, Steinsson K, Grondal G, Valdimarsson H (2007) Patients with rheumatoid arthritis have higher levels of mannan-binding lectin than their firstdegree relatives and unrelated controls. J Rheumatol 34: 1692-1695.
26. Graudal NA, Homann C, Madsen HO, Svejgaard A, Jurik AG, et al. (1998) Mannan binding lectin in rheumatoid arthritis. A longitudinal study. J Rheumatol 25: 629-635. (Pubitemid 28212367)
27. Ip WK, Lau YL, Chan SY, Mok CC, Chan D, et al. (2000) Mannose-binding lectin and rheumatoid arthritis in southern Chinese. Arthritis Rheum 43: 1679-1687.
28. Graudal N (2004) The natural history and prognosis of rheumatoid arthritis: association of radiographic outcome with process variables, joint motion and immune proteins. Scand J Rheumatol Suppl 118: 1-38.
29. Graudal NA, Madsen HO, Tarp U, Svejgaard A, Jurik G, et al. (2000) The association of variant mannose-binding lectin genotypes with radiographic outcome in rheumatoid arthritis. Arthritis Rheum 43: 515-521. (Pubitemid 30394941)
30. Velavan TP, Boldt AB, Tomiuk J, Seibold F, Schoepfer AM, et al. (2010) Variant alleles of the mannose binding lectin 2 gene (MBL2) confer heterozygote advantage within Crohn's families. Scand J Gastroenterol 45: 1129-1130.
31. Boldt AB, Messias-Reason IJ, Meyer D, Schrago CG, Lang F, et al. (2010) Phylogenetic nomenclature and evolution of mannose-binding lectin (MBL2) haplotypes. BMC Genet 11: 38.
32. Larsen F, Madsen HO, Sim RB, Koch C, Garred P (2004) Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein. J Biol Chem 279: 21302-21311. (Pubitemid 38656537)
33. Madsen HO, Garred P, Thiel S, Kurtzhals JA, Lamm LU, et al. (1995) Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 155: 3013-3020.
34. Antony JS, Ojurongbe O, van TH, Ouf EA, Engleitner T, et al. (2013) Mannose-binding lectin and susceptibility to schistosomiasis. J Infect Dis 207: 1675-1683.
35. Madsen HO, Garred P, Thiel S, Kurtzhals JA, Lamm LU, et al. (1995) Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 155: 3013-3020.
36. Dommett RM, Klein N, Turner MW (2006) Mannose-binding lectin in innate immunity: past, present and future. Tissue Antigens 68: 193-209. (Pubitemid 44341793)
37. Madsen HO, Satz ML, Hogh B, Svejgaard A, Garred P (1998) Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America. J Immunol 161: 3169-3175. (Pubitemid 28425746)
38. Bernig T, Taylor JG, Foster CB, Staats B, Yeager M, et al. (2004) Sequence analysis of the mannose-binding lectin (MBL2) gene reveals a high degree of heterozygosity with evidence of selection. Genes Immun 5: 461-476. (Pubitemid 39263882)
39. Verdu P, Barreiro LB, Patin E, Gessain A, Cassar O, et al. (2006) Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles. Hum Mol Genet 15: 2650-2658. (Pubitemid 44288693)
40. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, et al. (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31: 315-324. (Pubitemid 18091653)
41. Martiny FL, Veit TD, Brenol CV, Brenol JC, Xavier RM, et al. (2012) Mannose-binding lectin gene polymorphisms in Brazilian patients with rheumatoid arthritis. J Rheumatol 39: 6-9.
42. Petersen SV, Thiel S, Jensen L, Steffensen R, Jensenius JC (2001) An assay for the mannan-binding lectin pathway of complement activation. J Immunol Methods 257: 107-116. (Pubitemid 33001238)
43. (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
44. MacKay K, Eyre S, Myerscough A, Milicic A, Barton A, et al. (2002) Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom. Arthritis Rheum 46: 632-639. (Pubitemid 34214245)
45. Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, et al. (2004) A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22. is associated with rheumatoid arthritis. Am J Hum Genet 75: 330-337. (Pubitemid 38943877)
46. Hinks A, Eyre S, Barton A, Thomson W, Worthington J (2007) Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK. Ann Rheum Dis 66: 683-686. (Pubitemid 46707140)
47. Di MG, Perricone C, Ballanti E, Kroegler B, Greco E, et al. (2011) Complement system and rheumatoid arthritis: relationships with autoantibodies, serological, clinical features, and anti-TNF treatment. Int J Immunopathol Pharmacol 24: 357-366.
48. Ballanti E, Perricone C, Di MG, Kroegler B, Chimenti MS, et al. (2011) Role of the complement system in rheumatoid arthritis and psoriatic arthritis: relationship with anti-TNF inhibitors. Autoimmun Rev 10: 617-623.
49. Okroj M, Heinegard D, Holmdahl R, Blom AM (2007) Rheumatoid arthritis and the complement system. Ann Med 39: 517-530. (Pubitemid 350035568)
50. Jose PJ, Moss IK, Maini RN, Williams TJ (1990) Measurement of the chemotactic complement fragment C5a in rheumatoid synovial fluids by radioimmunoassay: role of C5a in the acute inflammatory phase. Ann Rheum Dis 49: 747-752. (Pubitemid 20346376)
51. Boldt AB, Messias-Reason IJ, Lell B, Issifou S, Pedroso ML, et al. (2009) Haplotype specific-sequencing reveals MBL2 association with asymptomatic Plasmodium falciparum infection. Malar J 8: 97.
52. Jha AN, Sundaravadivel P, Singh VK, Pati SS, Patra PK, et al. (2014) MBL2 variations and malaria susceptibility in Indian populations. Infect Immun 82: 52-61.
53. Glesse N, Monticielo OA, Mattevi VS, Brenol JC, Xavier RM, et al. (2011) Association of mannose-binding lectin 2 gene polymorphic variants with susceptibility and clinical progression in systemic lupus erythematosus. Clin Exp Rheumatol 29: 983-990.
54. Im CH, Kim J, Lee YJ, Lee EY, Lee EB, et al. (2012) Mannose-binding lectin 2 gene haplotype analysis in Korean patients with ankylosing spondylitis. Rheumatol Int 32: 2251-2255.
55. Sandrin-Garcia P, Brandao LA, Coelho AV, Guimaraes RL, Pancoto JA, et al. (2011) Mannose binding lectin gene (MBL2) functional polymorphisms are associated with systemic lupus erythematosus in southern Brazilians. Hum Immunol 72: 516-521.
56. Saevarsdottir S, Ding B, Steinsson K, Grondal G, Valdimarsson H, et al. (2011) Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers. Arthritis Res Ther 13: R65.
57. van de Geijn FE, Hazes JM, Geleijns K, Emonts M, Jacobs BC, et al. (2008) Mannose-binding lectin polymorphisms are not associated with rheumatoid arthritis-confirmation in two large cohorts. Rheumatology (Oxford) 47: 1168-1171. (Pubitemid 352038221)
58. Xie Q, Wang SC, Bian G, Zhan FL, Xie JK, et al. (2012) Association of MIF-173G/C and MBL2 codon 54 gene polymorphisms with rheumatoid arthritis: a meta-analysis. Hum Immunol 73: 966-971.
59. Troelsen LN, Garred P, Jacobsen S (2010) Mortality and predictors of mortality in rheumatoid arthritis-a role for mannose-binding lectin? J Rheumatol 37: 536-543.
60. Maffei G, Brouwer N, Dolman KM, van d, V, Roos D, et al. (2005) Plasma levels of mannan-binding lectin in relation to periodontitis and smoking. J Periodontol 76: 1881-1889. (Pubitemid 41748977)
61. Ammitzboll CG, Thiel S, Ellingsen T, Deleuran B, Jorgensen A, et al. (2012) Levels of lectin pathway proteins in plasma and synovial fluid of rheumatoid arthritis and osteoarthritis. Rheumatol Int 32: 1457-1463.
62. Swaak AJ, Van RA, Planten O, Han H, Hattink O, et al. (1987) An analysis of the levels of complement components in the synovial fluid in rheumatic diseases. Clin Rheumatol 6: 350-357.
63. Ojurongbe O, Ouf EA, van TH, Toan NL, Song lH, et al. (2012) Reliable and rapid characterization of functional FCN2 gene variants reveals diverse geographical patterns. BMC Med Genet 13: 37.
64. Vander CB, Nuytinck L, Boullart L, Elewaut D, Waegeman W, et al. (2007) Polymorphisms in the ficolin 1 gene (FCN1) are associated with susceptibility to the development of rheumatoid arthritis. Rheumatology (Oxford) 46: 1792-1795.