The association of variant mannose-binding lectin genotypes with radiographic outcome in rheumatoid arthritis

Arthritis and Rheumatism

Volumn 43, Issue 3, 2000, Pages 515-521

  Graudal, Niels A ^a,b   Madsen, Hans O ^b   Tarp, Ulrik ^a   Svejgaard, Arne ^b   Jurik, Anne Grethe ^a   Graudal, Hans K ^c   Garred, Peter ^b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b Rigshospitalet   (Denmark)

^c Department of Clinical Immunology ^*

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; MANNOSE BINDING PROTEIN;

ADOLESCENT; ADULT; ALLELE; ARTHROPATHY; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GENE EXPRESSION; GENOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIOGRAPHY; RHEUMATOID ARTHRITIS; RISK FACTOR; SCORING SYSTEM; TREATMENT OUTCOME;

ADOLESCENT; ADULT; ALLELES; ARTHRITIS, RHEUMATOID; CARRIER PROTEINS; COLLECTINS; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; VARIATION (GENETICS);

EID: 0034096897     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200003)43:3<515::AID-ANR6>3.0.CO;2-T     Document Type: Article

References (60)

1. Ryley NG, Heryet AR, Lu J, Reid KBM, Fleming KA. Mannan-binding protein in human liver. J Immunol Methods 1991;141: 73-9.
2. Matsushita M, Fujita T. Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease. J Exp Med 1992;176:1497-503.
3. Thiel S, Vorup-Jensen T, Stover CM, Schwaeble W, Laursen SB, Poulsen K, et al. A second serine protease associated with mannan-binding lectin that activates complement. Nature 1997; 386:506-10.
4. Kuhlman M, Joiner K, Ezekowitz RAB. The human mannose-binding protein functions as an opsonin. J Exp Med 1989;169: 1733-45.
5. Guo N, Mogues T, Weremovicz S, Morton CC, Sastry KN. The human ortholog of rhesus mannose-binding protein-A gene is an expressed pseudogene that localizes to chromosome 10. Mamm Genome 1998;9:246-9.
6. Madsen HO, Garred P, Thiel S, Kurtzhals JAL, Lamm LU, Ryder LP, et al. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 1995;155:3013-20.
7. Madsen HO, Satz ML, Hogh B, Svejgaard A, Garred P. Different molecular events result in low protein levels of mannan-binding lectin in populations from south east Africa and South America. J Immunol 1998;161:3169-75.
8. Sumiya M, Super M, Tabona P, Levinsky RJ, Arai T, Turner MW, et al. Molecular basis of opsonic defect in immunodeficient children. Lancet 1991;337:1569-70.
9. Summerfield JA, Ryder S, Sumiya M, Thursz M, Gorchein A, Monteil MA, et al. Mannose binding protein gene mutations associated with unusual and severe infections in adults. Lancet 1995;345:886-9.
10. Garred P, Madsen HO, Hofmann B, Svejgaard A. Increased frequency of homozygosity of abnormal mannan-binding protein alleles in patients with suspected immunodeficiency. Lancet 1995; 346:941-3.
11. Garred P, Madsen HO, Balslev U, Hofmann B, Pedersen C, Gerstoft J, et al. Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin. Lancet 1997;349:236-40.
12. Summerfield JA, Sumiya M, Levin M, Turner MW. Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series. BMJ 1997;314:1229-32.
13. Davies EJ, Snowden N, Hillarby MC, Carthy D, Grennan DM, Thomson W, et al. Mannose-binding protein gene polymorphism in systemic lupus erythematosus. Arthritis Rheum 1995;38:110-4.
14. Sullivan KE, Wooten C, Goldman D, Petri M. Mannose-binding protein genetic polymorphisms in black patients with systemic lupus erythematosus. Arthritis Rheum 1996;39:2046-51.
15. Ip WK, Chan SY, Lau CS, Lau YL. Association of systemic lupus erythematosus with promoter polymorphisms of the mannose-binding lectin gene. Arthritis Rheum 1998;41:1663-8.
16. Foster CB, Lehrnbecker T, Mol F, Steinberg SM, Venzon DJ, Walsch TJ, et al. Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease. J Clin Invest 1998;102:2146-55.
17. Garred P, Madsen HO, Halberg P, Petersen J, Kronborg G, Svejgaard A, et al. Mannose-binding lectin polymorphisms and susceptibility to infection in systemic lupus erythematosus. Arthritis Rheum 1999;42:2145-52.
18. Graudal N, Homann C, Madsen HO, Svejgaard A, Jurik AG, Graudal HK, et al. Mannan-binding lectin in rheumatoid arthritis: a longitudinal study. J Rheumatol 1998;25:629-35.
19. Committee of the American Rheumatism Association. 1958 revision of diagnostic criteria for rheumatoid arthritis. Arthritis Rheum 1959;2:16-20.
20. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
21. Larsen A, Dale K, Eek M. Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films. Acta Radiol Diagn 1976;18:481-91.
22. Graudal N, Jurik AG, de Carvalho A, Graudal HK. Radiographic progression in rheumatoid arthritis: a long-term prospective study of 109 patients. Arthritis Rheum 1998;41:1470-80.
23. Garred P, Madsen HO, Kurtzhals JAL, Lamm LU, Thiel S, Hey AS, et al. Diallelic polymorphism may explain variations of blood concentration of mannan-binding protein in Eskimos, but not in black Africans. Eur J Immunogenet 1992;19:403-12.
24. Miller S, Dykes D, Polesky H. A simple salting out procedure for extracting DNA from nucleated cells. Nucleic Acids Res 1988;16: 1215.
25. Garred P, Madsen HO, Svejgaard A. Genetics of human mannan-binding protein. In: Ezekowitz RAB, Sastry K, Reid KMB, editors. Collectin and innate immunity. Austin, Texas: RG Landes; 1996. p. 139-64.
26. Brower AC. Use of the radiograph to measure the course of rheumatoid arthritis: the gold standard versus fool's gold. Arthritis Rheum 1990;33:316-24.
27. Sharp JT. Radiologic assessment as an outcome measure in rheumatoid arthritis. Arthritis Rheum 1989;32:221-9.
28. Graudal N, Tarp U, Jurik AG, Galløe AM, Garred P, Milman N, et al. Inflammatory patterns in rheumatoid arthritis estimated by the number of swollen and tender joints, the erythrocyte sedimentation rate and hemoglobin: the long-term course and the association to the radiographic progression. J Rheumatol. 2000;27:47-55.
29. Vingsbo-Lundberg C, Nordquist N, Olofson P, Sundvall M, Saxne T, Petterson U, et al. Genetic control of arthritis onset, severity and chronicity in a model for rheumatoid arthritis in rats. Nat Genet 1998;20:401-4.
30. Stastny P. Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. N Engl J Med 1978;298:869-71.
31. Young A, Jaraquemada D, Awad J, Festenstein H, Corbett M, Hay FC, et al. Association of HLA-DR4/Dw4 and DR2/Dw2 with radiologic changes in a prospective study of patients with rheumatoid arthritis: preferential relationship with HLA-Dw rather than HLA-DR specificities. Arthritis Rheum 1984;27:20-5.
32. Calin A, Elswood J, Klouda PT. Destructive arthritis, rheumatoid factor, and HLA-DR4: susceptibility versus severity, a case-control study. Arthritis Rheum 1989;32:1221-5.
33. Jaraquemada D, Ollier W, Awad J, Young A, Silman A, Roitt JM, et al. HLA and rheumatoid arthritis: a combined analysis of 440 British patients. Ann Rheum Dis 1986;45:627-36.
34. Olsen NJ, Callahan LF, Brooks RH, Nance EP, Kaye JJ, Stastny P, et al. Associations of HLA-DR4 with rheumatoid factor and radiographic severity in rheumatoid arthritis. Am J Med 1988;84: 257-64.
35. Van Zeben D, Hazes JMW, Zwinderman AH, Cats A, Schreuder GMT, D'Amaro J, et al. Association of HLA-DR4 with a more progressive disease course in patients with rheumatoid arthritis: results of a followup study. Arthritis Rheum 1991;34:822-30.
36. Mottonen TT. Prediction of erosiveness and rate of development of new erosions in early rheumatoid arthritis. Ann Rheum Dis 1988;47:648-53.
37. Westedt ML, Breedveld FC, Schreuder GMTH, D'Amaro J, Cats A, DeVries RRP. Immunogenetic heterogeneity of rheumatoid arthritis. Ann Rheum Dis 1986;45:534-8.
38. Silman AJ, Reeback AJ, Jaraquemada D. HLA-DR4 as predictor of outcome 3 years after onset of rheumatoid arthritis. Rheumatol Int 1986;6:233-5.
39. Stockman A, Emery P, Doyle T, Hopper J, Tait B, Muirden K. Relationship of progression of radiographic changes in hands and wrists, clinical features and HLA-DR antigens in rheumatoid arthritis. J Rheumatol 1991;18:1001-7.
40. Van der Heijde DM, van Riel PL, van Leeuwen MA, van't Hof MA, van Rijswijk MH, van de Putte LB. Prognostic factors for radiographic damage and physical ability in early rheumatoid arthritis: a prospective follow-up study of 147 patients. Br J Rheumatol 1992;31:519-25.
41. Van Zeben D, Hazes JMW, Zwinderman AH, Vandenbroucke JP, Breedveld FC. Factors predicting outcome of rheumatoid arthritis: results of a follow-up study. J Rheumatol 1993;20:1288-96.
42. Garred P, Pressler T, Madsen HO, Fredcriksen B, Svejgaard A, Høiby N, et al. Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. J Clin Invest 1999;104:431-7.
43. Kilpatrick DC. Mannan-binding protein in sera positive for rheumatoid factor. Br J Rheumatol 1997;36:207-9.
44. Stanworth SJ, Donn RP, Hassall A, Dawes P, Ollier W, Snowden N. Absence of an association between mannose-binding lectin polymorphism and rheumatoid arthritis. Br J Rheumatol 1998;37: 186-8.
45. Garred P, Madsen HO, Marquart H, Hansen TM, Sørensen SF, Petersen J, et al. Two edged role of mannose-binding lectin in rheumatoid arthritis: a cross sectional study. J Rheumatol 2000; 27:26-34.
46. Parekh RB, Dwek RA, Sutton BJ, Fernandes DL, Leung A, Stanworth D, et al. Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG. Nature 1985;316:452-7.
47. Rademacher TW, Williams P, Dwek RA. Agalactosyl glycoforms of IgG autoantihodies are pathogenic. Proc Natl Acad Sci U S A 1994;91:6123-7.
48. Parekh RB, Isenberg DA, Ansell BM, Roitt IM, Dwek RA, Rademacher TW. Galactosylation of IgG associated oligosaccharides: reduction in patients with adult and juvenile onset rheumatoid arthritis and relation to disease activity. Lancet 1988;1:966-9.
49. Young A, Sumar N, Bodman K, Goyal S, Sinclair H, Roitt I, et al. Agalactosyl IgG: an aid to differential diagnosis in early synovitis. Arthritis Rheum 1991;34:1425-9.
50. Van Zeben D, Rook GA, Hazes JM, Zwinderman AH, Zhang Y, Ghelani S, et al. Early agalactosylation of IgG is associated with a more progressive disease course in patients with rheumatoid arthritis: results of a follow-up study. Br J Rheumatol 1994;33: 36-43.
51. Bodman-Smith K, Sumar N, Sinclair H, Roitt I, Isenberg D, Young A. Agalactosyl IgG (Gal-0) - an analysis of its clinical utility in the long-term follow-up of patients with rheumatoid arthritis. Br J Rheumatol 1996;35:1063-6.
52. Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, Sim RB. Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via mannose-binding protein. Nat Med 1995;1:237-43.
53. Morgan BP, Walport MJ. Complement deficiency and disease. Immunol Today 1991;12:301-6.
54. Bowness P, Davies KA, Norsworthy PJ, Athanassiou P, Taylor-Wiedeman J, Borysiewicz LK, et al. Hereditary C1q deficiency and systemic lupus erythematosus. QJM 1994;87:455-64.
55. Korb LC, Ahearn JM, C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes. J Immunol 1997; 158:4525-8.
56. Botto M, Agnola CD, Bygrave AE, Thompson EM, Cook HT, Petry F, et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 1998;19:56-9.
57. Turner MW. Mannose-binding lectin in health and disease. Immunobiology 1998;199:327-39.
58. Soell M, Lett E, Holveck F, Schöller M, Wachsmann D, Klein J-P. Activation of human monocytes by streptococcal rhamnose glucose polymers is mediated by CD14 antigen and mannan binding protein inhibits TNF-alpha release. J Immunol 1995;154:851-60.
59. Chaka W, Verheul AFM, Vaishnav VV, Cherniak R, Scharringa JJ, Ver J, et al. Induction of TNF in human peripheral blood mononuclear cells by the mannoprotein of Cryptococcus neoformans involves human mannose binding protein. J Immunol 1997; 159:2979-85.
60. Elliot MJ, Ravinder NM, Feldmann M, Kalden JR, Antoni C, Smolen JS, et al. Randomised double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor alfa (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-10.