-
1
-
-
33947593538
-
Composition and three-dimensional em structure of double affinity-purified, human prespliceosomal A complexes
-
Behzadnia, N., Golas, M.M., Hartmuth, K., Sander, B., Kastner, B., Deckert, J., Dube, P., Will, C.L., Urlaub, H., Stark, H. et al. (2007) Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. EMBO J., 26, 1737-1748.
-
(2007)
EMBO J.
, vol.26
, pp. 1737-1748
-
-
Behzadnia, N.1
Golas, M.M.2
Hartmuth, K.3
Sander, B.4
Kastner, B.5
Deckert, J.6
Dube, P.7
Will, C.L.8
Urlaub, H.9
Stark, H.10
-
2
-
-
0031878108
-
A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site
-
Gozani, O., Potashkin, J. and Reed, R. (1998) A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site. Mol. Cell. Biol., 18, 4752-4760.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4752-4760
-
-
Gozani, O.1
Potashkin, J.2
Reed, R.3
-
3
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
Wahl, M.C., Will, C.L. and Luhrmann, R. (2009) The spliceosome: design principles of a dynamic RNP machine. Cell, 136, 701-718.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Luhrmann, R.3
-
4
-
-
77149180424
-
Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing
-
Lardelli, R.M., Thompson, J.X., Yates, J.R. III and Stevens, S.W. (2010) Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing. RNA, 16, 516-528.
-
(2010)
RNA
, vol.16
, pp. 516-528
-
-
Lardelli, R.M.1
Thompson, J.X.2
Yates III, J.R.3
Stevens, S.W.4
-
5
-
-
77954752911
-
Intragenic chromatin modifications: A new layer in alternative splicing regulation
-
Schor, I.E., Allo, M. and Kornblihtt, A.R. (2010) Intragenic chromatin modifications: a new layer in alternative splicing regulation. Epigenetics, 5, 174-179.
-
(2010)
Epigenetics
, vol.5
, pp. 174-179
-
-
Schor, I.E.1
Allo, M.2
Kornblihtt, A.R.3
-
6
-
-
84872373404
-
Transcriptional elongation and alternative splicing
-
Dujardin, G., Lafaille, C., Petrillo, E., Buggiano, V., Gomez Acuna, L.I., Fiszbein, A., Godoy Herz, M.A., Nieto Moreno, N., Munoz, M.J., Allo, M. et al. (2013) Transcriptional elongation and alternative splicing. Biochim. Biophys. Acta., 1829, 134-140.
-
(2013)
Biochim. Biophys. Acta.
, vol.1829
, pp. 134-140
-
-
Dujardin, G.1
Lafaille, C.2
Petrillo, E.3
Buggiano, V.4
Gomez Acuna, L.I.5
Fiszbein, A.6
Godoy Herz, M.A.7
Nieto Moreno, N.8
Munoz, M.J.9
Allo, M.10
-
7
-
-
70349333201
-
Nucleosomes are well positioned in exons and carry characteristic histone modifications
-
Andersson, R., Enroth, S., Rada-Iglesias, A., Wadelius, C. and Komorowski, J. (2009) Nucleosomes are well positioned in exons and carry characteristic histone modifications. Genome Res., 19, 1732-1741.
-
(2009)
Genome Res.
, vol.19
, pp. 1732-1741
-
-
Andersson, R.1
Enroth, S.2
Rada-Iglesias, A.3
Wadelius, C.4
Komorowski, J.5
-
8
-
-
69949132191
-
Chromatin organization marks exon-intron structure
-
Schwartz, S., Meshorer, E. and Ast, G. (2009) Chromatin organization marks exon-intron structure. Nat. Struct. Mol. Biol., 16, 990-995.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 990-995
-
-
Schwartz, S.1
Meshorer, E.2
Ast, G.3
-
9
-
-
36249027156
-
Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing
-
Sims, R.J. III, Millhouse, S., Chen, C.F., Lewis, B.A., Erdjument-Bromage, H., Tempst, P., Manley, J.L. and Reinberg, D. (2007) Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Mol. Cell, 28, 665-676.
-
(2007)
Mol. Cell
, vol.28
, pp. 665-676
-
-
Sims III, R.J.1
Millhouse, S.2
Chen, C.F.3
Lewis, B.A.4
Erdjument-Bromage, H.5
Tempst, P.6
Manley, J.L.7
Reinberg, D.8
-
10
-
-
38849179519
-
Multiple alternative splicing markers for ovarian cancer
-
Klinck, R., Bramard, A., Inkel, L., Dufresne-Martin, G., Gervais-Bird, J., Madden, R., Paquet, E.R., Koh, C., Venables, J.P., Prinos, P. et al. (2008) Multiple alternative splicing markers for ovarian cancer. Cancer Res., 68, 657-663.
-
(2008)
Cancer Res.
, vol.68
, pp. 657-663
-
-
Klinck, R.1
Bramard, A.2
Inkel, L.3
Dufresne-Martin, G.4
Gervais-Bird, J.5
Madden, R.6
Paquet, E.R.7
Koh, C.8
Venables, J.P.9
Prinos, P.10
-
11
-
-
78751700506
-
Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer
-
Misquitta-Ali, C.M., Cheng, E., O'Hanlon, D., Liu, N., McGlade, C.J., Tsao, M.S. and Blencowe, B.J. (2011) Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer. Mol. Cell. Biol., 31, 138-150.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 138-150
-
-
Misquitta-Ali, C.M.1
Cheng, E.2
O'Hanlon, D.3
Liu, N.4
McGlade, C.J.5
Tsao, M.S.6
Blencowe, B.J.7
-
12
-
-
67349097457
-
Cancer-associated regulation of alternative splicing
-
Venables, J.P., Klinck, R., Koh, C., Gervais-Bird, J., Bramard, A., Inkel, L., Durand, M., Couture, S., Froehlich, U., Lapointe, E. et al. (2009) Cancer-associated regulation of alternative splicing. Nat. Struct. Mol. Biol., 16, 670-676.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 670-676
-
-
Venables, J.P.1
Klinck, R.2
Koh, C.3
Gervais-Bird, J.4
Bramard, A.5
Inkel, L.6
Durand, M.7
Couture, S.8
Froehlich, U.9
Lapointe, E.10
-
13
-
-
62449084935
-
Alternative splicing of Cyr61 is regulated by hypoxia and significantly changed in breast cancer
-
Hirschfeld, M., zur Hausen, A., Bettendorf, H., Jager, M. and Stickeler, E. (2009) Alternative splicing of Cyr61 is regulated by hypoxia and significantly changed in breast cancer. Cancer Res., 69, 2082-2090.
-
(2009)
Cancer Res.
, vol.69
, pp. 2082-2090
-
-
Hirschfeld, M.1
Zur Hausen, A.2
Bettendorf, H.3
Jager, M.4
Stickeler, E.5
-
14
-
-
0029837671
-
A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype
-
Collesi, C., Santoro, M.M., Gaudino, G. and Comoglio, P.M. (1996) A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype. Mol. Cell. Biol., 16, 5518-5526.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5518-5526
-
-
Collesi, C.1
Santoro, M.M.2
Gaudino, G.3
Comoglio, P.M.4
-
15
-
-
29144447982
-
Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene
-
Ghigna, C., Giordano, S., Shen, H., Benvenuto, F., Castiglioni, F., Comoglio, P.M., Green, M.R., Riva, S. and Biamonti, G. (2005) Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. Mol. Cell, 20, 881-890.
-
(2005)
Mol. Cell
, vol.20
, pp. 881-890
-
-
Ghigna, C.1
Giordano, S.2
Shen, H.3
Benvenuto, F.4
Castiglioni, F.5
Comoglio, P.M.6
Green, M.R.7
Riva, S.8
Biamonti, G.9
-
16
-
-
4544237763
-
Nuclear structure in cancer cells
-
Zink, D., Fischer, A.H. and Nickerson, J.A. (2004) Nuclear structure in cancer cells. Nat. Rev. Cancer, 4, 677-687.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 677-687
-
-
Zink, D.1
Fischer, A.H.2
Nickerson, J.A.3
-
17
-
-
84869051680
-
Perturbation of chromatin structure globally affects localization and recruitment of splicing factors
-
Schor, I.E., Lleres, D., Risso, G.J., Pawellek, A., Ule, J., Lamond, A.I. and Kornblihtt, A.R. (2012) Perturbation of chromatin structure globally affects localization and recruitment of splicing factors. PloS One, 7, e48084.
-
(2012)
PloS One
, vol.7
-
-
Schor, I.E.1
Lleres, D.2
Risso, G.J.3
Pawellek, A.4
Ule, J.5
Lamond, A.I.6
Kornblihtt, A.R.7
-
18
-
-
0030466895
-
New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action
-
Nakajima, H., Hori, Y., Terano, H., Okuhara, M., Manda, T., Matsumoto, S. and Shimomura, K. (1996) New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J. Antibiot. (Tokyo), 49, 1204-1211.
-
(1996)
J. Antibiot. (Tokyo)
, vol.49
, pp. 1204-1211
-
-
Nakajima, H.1
Hori, Y.2
Terano, H.3
Okuhara, M.4
Manda, T.5
Matsumoto, S.6
Shimomura, K.7
-
19
-
-
34548095157
-
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
-
Kaida, D., Motoyoshi, H., Tashiro, E., Nojima, T., Hagiwara, M., Ishigami, K., Watanabe, H., Kitahara, T., Yoshida, T., Nakajima, H. et al. (2007) Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nat. Chem. Biol., 3, 576-583.
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 576-583
-
-
Kaida, D.1
Motoyoshi, H.2
Tashiro, E.3
Nojima, T.4
Hagiwara, M.5
Ishigami, K.6
Watanabe, H.7
Kitahara, T.8
Yoshida, T.9
Nakajima, H.10
-
20
-
-
78049354837
-
Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation
-
Roybal, G.A. and Jurica, M.S. (2010) Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation. Nucleic Acids Res., 38, 6664-6672.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 6664-6672
-
-
Roybal, G.A.1
Jurica, M.S.2
-
21
-
-
79952220808
-
Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A
-
Corrionero, A., Minana, B. and Valcarcel, J. (2011) Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A. Genes Dev., 25, 445-459.
-
(2011)
Genes Dev.
, vol.25
, pp. 445-459
-
-
Corrionero, A.1
Minana, B.2
Valcarcel, J.3
-
22
-
-
70949100953
-
Synthetic mRNA splicing modulator compounds with in vivo antitumor activity
-
Lagisetti, C., Pourpak, A., Goronga, T., Jiang, Q., Cui, X., Hyle, J., Lahti, J.M., Morris, S.W. and Webb, T.R. (2009) Synthetic mRNA splicing modulator compounds with in vivo antitumor activity. J. Med. Chem., 52, 6979-6990.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 6979-6990
-
-
Lagisetti, C.1
Pourpak, A.2
Goronga, T.3
Jiang, Q.4
Cui, X.5
Hyle, J.6
Lahti, J.M.7
Morris, S.W.8
Webb, T.R.9
-
23
-
-
79961049732
-
Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing
-
Fan, L., Lagisetti, C., Edwards, C.C., Webb, T.R. and Potter, P.M. (2011) Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing. ACS Chem.l Biol., 6, 582-589.
-
(2011)
ACS Chem.l Biol.
, vol.6
, pp. 582-589
-
-
Fan, L.1
Lagisetti, C.2
Edwards, C.C.3
Webb, T.R.4
Potter, P.M.5
-
24
-
-
0033760404
-
Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced apoptosis and highly sensitive to TRAIL-induced apoptosis
-
Petak, I., Douglas, L., Tillman, D.M., Vernes, R. and Houghton, J.A. (2000) Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced apoptosis and highly sensitive to TRAIL-induced apoptosis. Clin. Cancer Res., 6, 4119-4127.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4119-4127
-
-
Petak, I.1
Douglas, L.2
Tillman, D.M.3
Vernes, R.4
Houghton, J.A.5
-
25
-
-
57249116888
-
Cross-hybridization modeling on Affymetrix exon arrays
-
Kapur, K., Jiang, H., Xing, Y. and Wong, W.H. (2008) Cross-hybridization modeling on Affymetrix exon arrays. Bioinformatics, 24, 2887-2893.
-
(2008)
Bioinformatics
, vol.24
, pp. 2887-2893
-
-
Kapur, K.1
Jiang, H.2
Xing, Y.3
Wong, W.H.4
-
26
-
-
84899793713
-
-
Stamm, S., Smith, C. and Luhrmann, L. (eds) Weinheim, Wiley-Blackwell
-
de La Grange, P. (2012) In: Stamm, S., Smith, C. and Luhrmann, L. (eds), Alternative pre-mRNA Splicing: Theory and Protocols. Weinheim, Wiley-Blackwell, pp. 261-267.
-
(2012)
Alternative Pre-mRNA Splicing: Theory and Protocols
, pp. 261-267
-
-
De La Grange, P.1
-
27
-
-
77950490438
-
MADS+: Discovery of differential splicing events from Affymetrix exon junction array data
-
Shen, S., Warzecha, C.C., Carstens, R.P. and Xing, Y. (2010) MADS+: discovery of differential splicing events from Affymetrix exon junction array data. Bioinformatics, 26, 268-269.
-
(2010)
Bioinformatics
, vol.26
, pp. 268-269
-
-
Shen, S.1
Warzecha, C.C.2
Carstens, R.P.3
Xing, Y.4
-
28
-
-
42249093677
-
Isolation of an active step i spliceosome and composition of its RNP core
-
Bessonov, S., Anokhina, M., Will, C.L., Urlaub, H. and Luhrmann, R. (2008) Isolation of an active step I spliceosome and composition of its RNP core. Nature, 452, 846-850.
-
(2008)
Nature
, vol.452
, pp. 846-850
-
-
Bessonov, S.1
Anokhina, M.2
Will, C.L.3
Urlaub, H.4
Luhrmann, R.5
-
29
-
-
0027459936
-
Small nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditions
-
Behrens, S.E., Tyc, K., Kastner, B., Reichelt, J. and Luhrmann, R. (1993) Small nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditions. Mol. Cell. Biol., 13, 307-319.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 307-319
-
-
Behrens, S.E.1
Tyc, K.2
Kastner, B.3
Reichelt, J.4
Luhrmann, R.5
-
30
-
-
84860725581
-
Functional coupling of transcription and splicing
-
Montes, M., Becerra, S., Sanchez-Alvarez, M. and Sune, C. (2012) Functional coupling of transcription and splicing. Gene, 501, 104-117.
-
(2012)
Gene
, vol.501
, pp. 104-117
-
-
Montes, M.1
Becerra, S.2
Sanchez-Alvarez, M.3
Sune, C.4
-
31
-
-
80052445151
-
Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36
-
de Almeida, S.F., Grosso, A.R., Koch, F., Fenouil, R., Carvalho, S., Andrade, J., Levezinho, H., Gut, M., Eick, D., Gut, I. et al. (2011) Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36. Nat. Struct. Mol. Biol., 18, 977-983.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 977-983
-
-
De Almeida, S.F.1
Grosso, A.R.2
Koch, F.3
Fenouil, R.4
Carvalho, S.5
Andrade, J.6
Levezinho, H.7
Gut, M.8
Eick, D.9
Gut, I.10
-
32
-
-
33845799903
-
Polycomb silencing mechanisms and the management of genomic programmes
-
Schwartz, Y.B. and Pirrotta, V. (2007) Polycomb silencing mechanisms and the management of genomic programmes. Nat. Rev. Genet., 8, 9-22.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 9-22
-
-
Schwartz, Y.B.1
Pirrotta, V.2
-
33
-
-
84866077515
-
Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion
-
Girard, C., Will, C.L., Peng, J., Makarov, E.M., Kastner, B., Lemm, I., Urlaub, H., Hartmuth, K. and Luhrmann, R. (2012) Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion. Nat. Commun., 3, 994.
-
(2012)
Nat. Commun.
, vol.3
, pp. 994
-
-
Girard, C.1
Will, C.L.2
Peng, J.3
Makarov, E.M.4
Kastner, B.5
Lemm, I.6
Urlaub, H.7
Hartmuth, K.8
Luhrmann, R.9
-
34
-
-
69949124307
-
Nucleosome positioning as a determinant of exon recognition
-
Tilgner, H., Nikolaou, C., Althammer, S., Sammeth, M., Beato, M., Valcarcel, J. and Guigo, R. (2009) Nucleosome positioning as a determinant of exon recognition. Nat. Struct. Mol. Biol., 16, 996-1001.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 996-1001
-
-
Tilgner, H.1
Nikolaou, C.2
Althammer, S.3
Sammeth, M.4
Beato, M.5
Valcarcel, J.6
Guigo, R.7
-
35
-
-
77149175671
-
Regulation of alternative splicing by histone modifications
-
Luco, R.F., Pan, Q., Tominaga, K., Blencowe, B.J., Pereira-Smith, O.M. and Misteli, T. (2010) Regulation of alternative splicing by histone modifications. Science, 327, 996-1000.
-
(2010)
Science
, vol.327
, pp. 996-1000
-
-
Luco, R.F.1
Pan, Q.2
Tominaga, K.3
Blencowe, B.J.4
Pereira-Smith, O.M.5
Misteli, T.6
-
36
-
-
84893210532
-
Regulation of alternative splicing by local histone modifications: Potential roles for RNA-guided mechanisms
-
Zhou, H.L., Luo, G., Wise, J.A. and Lou, H. (2013) Regulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanisms. Nucleic Acids Res., 42, 701-713.
-
(2013)
Nucleic Acids Res.
, vol.42
, pp. 701-713
-
-
Zhou, H.L.1
Luo, G.2
Wise, J.A.3
Lou, H.4
-
37
-
-
61349098460
-
Differential chromatin marking of introns and expressed exons by H3K36me3
-
Kolasinska-Zwierz, P., Down, T., Latorre, I., Liu, T., Liu, X.S. and Ahringer, J. (2009) Differential chromatin marking of introns and expressed exons by H3K36me3. Nat. Genet., 41, 376-381.
-
(2009)
Nat. Genet.
, vol.41
, pp. 376-381
-
-
Kolasinska-Zwierz, P.1
Down, T.2
Latorre, I.3
Liu, T.4
Liu, X.S.5
Ahringer, J.6
-
38
-
-
84878441552
-
Epigenetic memory in the context of nuclear reprogramming and cancer
-
Halley-Stott, R.P. and Gurdon, J.B. (2013) Epigenetic memory in the context of nuclear reprogramming and cancer. Brief Funct. Genomics, 12, 164-173.
-
(2013)
Brief Funct. Genomics
, vol.12
, pp. 164-173
-
-
Halley-Stott, R.P.1
Gurdon, J.B.2
-
39
-
-
84875537133
-
Epigenetic reprogramming in cancer
-
Suva, M.L., Riggi, N. and Bernstein, B.E. (2013) Epigenetic reprogramming in cancer. Science, 339, 1567-1570.
-
(2013)
Science
, vol.339
, pp. 1567-1570
-
-
Suva, M.L.1
Riggi, N.2
Bernstein, B.E.3
-
40
-
-
35848950003
-
Prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast
-
Boon, K.L., Grainger, R.J., Ehsani, P., Barrass, J.D., Auchynnikava, T., Inglehearn, C.F. and Beggs, J.D. (2007) prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast. Nat. Struct. Mol. Biol., 14, 1077-1083.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 1077-1083
-
-
Boon, K.L.1
Grainger, R.J.2
Ehsani, P.3
Barrass, J.D.4
Auchynnikava, T.5
Inglehearn, C.F.6
Beggs, J.D.7
|