Visualization of acute liver damage induced by cycloheximide in rats using PET with [18F]FEDAC, a radiotracer for translocator protein (18 kDa)

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Hatori, Akiko ^a   Yui, Joji ^a   Xie, Lin ^a   Yamasaki, Tomoteru ^a   Kumata, Katsushi ^a   Fujinaga, Masayuki ^a   Wakizaka, Hidekatsu ^a   Ogawa, Masanao ^a   Nengaki, Nobuki ^a   Kawamura, Kazunori ^a   Zhang, Ming Rong ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; MESSENGER RNA; N BENZYL N METHYL 2 [7,8 DIHYDRO 7 (2 FLUOROETHYL) 8 OXO 2 PHENYL 9H PURIN 9 YL]ACETAMIDE F 18; RECEPTOR PROTEIN; TRACER; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL DEATH; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; DRUG UPTAKE; GENE EXPRESSION; HEPATITIS; INFLAMMATORY CELL; KUPFFER CELL; LIVER CELL; LIVER INJURY; MACROPHAGE; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; RADIOACTIVITY; RAT; SENSITIVITY AND SPECIFICITY; TISSUE SECTION;

ACETAMIDES; ANIMALS; CARRIER PROTEINS; CYCLOHEXIMIDE; DRUG-INDUCED LIVER INJURY; IMMUNOENZYME TECHNIQUES; MALE; POSITRON-EMISSION TOMOGRAPHY; PROTEIN SYNTHESIS INHIBITORS; PROTEIN TRANSPORT; PURINES; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, GABA-A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TISSUE DISTRIBUTION;

EID: 84899835616     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086625     Document Type: Article

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