Translocator protein (18 kDa), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease

Journal of Hepatology

Volumn 57, Issue 5, 2012, Pages 1076-1082

  Xie, Lin ^a   Yui, Joji ^a   Hatori, Akiko ^a   Yamasaki, Tomoteru ^a   Kumata, Katsushi ^a   Wakizaka, Hidekatsu ^a   Yoshida, Yuichiro ^a,b   Fujinaga, Masayuki ^a   Kawamura, Kazunori ^a   Zhang, Ming Rong ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b 141 0032   (Japan)

Author keywords

18F FEDAC; Biomarker; Mitochondria; Molecular imaging; Non alcoholic fatty liver disease; Positron emission tomography; Translocator protein (18 kDa)

Indexed keywords

BENZODIAZEPINE RECEPTOR; BIOLOGICAL MARKER; CARRIER PROTEIN; CHOLINE; METHIONINE; N BENZYL N METHYL 2 [7,8 DIHYDRO 7 (2 FLUOROETHYL) 8 OXO 2 PHENYL 9H PURIN 9 YL]ACETAMIDE F 18; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIAGNOSTIC IMAGING; DISEASE ACTIVITY; DISEASE COURSE; FATTY LIVER; HISTOPATHOLOGY; MACROMOLECULE; MALE; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL MEMBRANE; MOLECULAR IMAGING; MOUSE; NON INVASIVE MEASUREMENT; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SCORING SYSTEM; SIGNAL TRANSDUCTION;

ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FATTY LIVER; FLUORINE RADIOISOTOPES; LIVER; MALE; MICE; MICE, INBRED C57BL; POSITRON-EMISSION TOMOGRAPHY; RECEPTORS, GABA; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84867578801     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.07.002     Document Type: Article

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