Neutralization of iL-10 exacerbates cycloheximide-Induced hepatocellular apoptosis and necrosis

Toxicologic Pathology

Volumn 37, Issue 4, 2009, Pages 536-546

  Kumagai, Kazuyoshi ^a   Ito, Kazumi ^a   Ando, Yosuke ^a   Hakamata, Shinobu ^a   Teranishi, Munehiro ^a   Nakayama, Hiroyuki ^b   Manabe, Sunao ^a  

^a DAIICHI SANKYO CO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; Cycloheximide; Interleukin 10; Liver; Neutralizing antibody

Indexed keywords

CASPASE; CYCLOHEXIMIDE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA; NEUTRALIZING ANTIBODY; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DISEASE EXACERBATION; ENZYME ACTIVITY; ENZYME ASSAY; GENE EXPRESSION; KUPFFER CELL; LIVER CELL; LIVER NECROSIS; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SERODIAGNOSIS; UPREGULATION;

ANIMALS; ANTIBODIES; APOPTOSIS; CASPASES; CYCLOHEXIMIDE; CYTOKINES; DATA INTERPRETATION, STATISTICAL; HEPATOCYTES; INTERLEUKIN-10; LIVER; LIVER DISEASES; MALE; NECROSIS; NEUTRALIZATION TESTS; NEUTROPHIL INFILTRATION; RATS; RATS, INBRED F344; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

CAPRA HIRCUS; RATTUS;

EID: 68649098281     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623309336153     Document Type: Article

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