Intravenous injection of cycloheximide induces apoptosis and up-regulates p53 and Fas receptor expression in the rat liver in vivo

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 457, Issue 1-2, 2000, Pages 105-111

  Higami, Yoshikazu ^a   Tanaka, Kenji ^a   Tsuchiya, Tomoshi ^a   Shimokawa, Isao ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Apoptosis; Cycloheximide (CHX); Fas receptor; Hepatocytes; P53

Indexed keywords

CELL RECEPTOR; CYCLOHEXIMIDE; FAS RECEPTOR; MESSENGER RNA; PROTEIN P53; PROTEIN SYNTHESIS INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOSE TIME EFFECT RELATION; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN INDUCTION; RAT;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CYCLOHEXIMIDE; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INJECTIONS, INTRAVENOUS; LIVER; MALE; MODELS, BIOLOGICAL; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

ANIMALIA;

EID: 0034695027     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(00)00132-9     Document Type: Article

References (22)

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