Integrated testing strategy (ITS) for bioaccumulation assessment under REACH

Environment International

Volumn 69, Issue , 2014, Pages 40-50

  Lombardo, Anna ^a   Roncaglioni, Alessandra ^a   Benfentati, Emilio ^a   Nendza, Monika ^b   Segner, Helmut ^c   Fernández, Alberto ^d   Kühne, Ralph ^e   Franco, Antonio ^f,g   Pauné, Eduard ^h   Schüürmann, Gerrit ^e,i  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b Analytisches Laboratorium   (Germany)

^c UNIVERSITY OF BERN   (Switzerland)

^d UNIVERSITAT ROVIRA I VIRGILI   (Spain)

^e HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^f TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^g UNILEVER RESEARCH   (United Kingdom)

^h SIMPPLE SL   (Spain)

ⁱ TU BERGAKADEMIE FREIBERG   (Germany)

Author keywords

Alternative methods; Bioaccumulation; In silico methods; Integrated testing strategy; REACH; Reduce animal testing

Indexed keywords

ANIMALS; BIOCHEMISTRY; INDUSTRIAL CHEMICALS; ORGANIC CHEMICALS;

ALTERNATIVE METHODS; ANIMAL TESTING; IN-SILICO; INTEGRATED TESTING STRATEGIES; REACH;

BIOACCUMULATION;

INDUSTRIAL CHEMICAL; ORGANIC COMPOUND;

BIOACCUMULATION; EUROPEAN UNION; HAZARD ASSESSMENT; INTEGRATED APPROACH; ORGANIC COMPOUND;

ARTICLE; BIOACCUMULATION; CALCULATION; CHEMICAL ANALYSIS; COMPUTER MODEL; DEGRADATION; ECOTOXICITY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT ASSESSMENT; ENVIRONMENTAL PROTECTION; INFORMATION PROCESSING; INTEGRATED TESTING STRATEGY; METABOLISM; PHYSICAL CHEMISTRY; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROBABILITY; TOXICITY TESTING;

EUROPE;

ALTERNATIVE METHODS; BIOACCUMULATION; IN SILICO METHODS; INTEGRATED TESTING STRATEGY; REACH; REDUCE ANIMAL TESTING;

ANIMAL TESTING ALTERNATIVES; ANIMALS; EUROPEAN UNION; GOVERNMENT REGULATION; GUIDELINES AS TOPIC; HAZARDOUS SUBSTANCES; HUMANS; MANDATORY REPORTING; ORGANIC CHEMICALS; RISK ASSESSMENT; TOXICITY TESTS;

EID: 84899809733     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2014.04.005     Document Type: Article

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